Page last updated: 2024-10-29

ketamine and Nociceptive Pain

ketamine has been researched along with Nociceptive Pain in 10 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.

Research Excerpts

ExcerptRelevanceReference
"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics."7.96Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020)
"Managing severe acute nociceptive pain in buprenorphine-maintained individuals for opioid use disorder management is challenging owing to the high affinity and very slow dissociation of buprenorphine from μ-opioid receptors that hinders the use of full agonist opioid analgesics."3.96Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia. ( Bounes, V; Coutens, B; Derreumaux, C; Frances, B; Guiard, BP; Labaste, F; Minville, V; Moulédous, L; Roussin, A, 2020)
"Mepivacaine horses were given mepivacaine 2% (3."2.87Local mepivacaine before castration of horses under medetomidine isoflurane balanced anaesthesia is effective to reduce perioperative nociception and cytokine release. ( Abass, M; Bettschart-Wolfensberger, R; Garzón, JFG; Kühnle, C; Picek, S; Zaghlou, A, 2018)
" We studied whether 6-hydroxynorketamine could affect nociception or the effects of morphine in acute or chronic administration settings."1.48Interactions of (2S,6S;2R,6R)-Hydroxynorketamine, a Secondary Metabolite of (R,S)-Ketamine, with Morphine. ( Jokinen, V; Kalso, EA; Lilius, TO; Niemi, M; Rauhala, PV; Viisanen, H, 2018)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Li, A1
Liu, Y1
Zhang, Q1
Friesner, I1
Jee, HJ1
Chen, ZS1
Wang, J1
Coutens, B1
Derreumaux, C1
Labaste, F1
Minville, V1
Guiard, BP1
Moulédous, L1
Bounes, V1
Roussin, A1
Frances, B1
Lilius, TO1
Viisanen, H1
Jokinen, V1
Niemi, M1
Kalso, EA1
Rauhala, PV1
Abass, M1
Picek, S1
Garzón, JFG1
Kühnle, C1
Zaghlou, A1
Bettschart-Wolfensberger, R1
Davison, SN1
Ebrahimi-Ghiri, M1
Shahini, F1
Khakpai, F1
Zarrindast, MR1
Hardy, J1
Quinn, S1
Fazekas, B1
Agar, M1
Currow, D1
Pacheco, Dda F1
Romero, TR1
Duarte, ID1
Bollag, L1
Ortner, CM1
Jelacic, S1
Rivat, C1
Landau, R1
Richebé, P1
Hussain, AM1
Khan, MA1

Trials

1 trial available for ketamine and Nociceptive Pain

ArticleYear
Local mepivacaine before castration of horses under medetomidine isoflurane balanced anaesthesia is effective to reduce perioperative nociception and cytokine release.
    Equine veterinary journal, 2018, Volume: 50, Issue:6

    Topics: Analgesics; Anesthesia; Anesthetics, Local; Animals; Arterial Pressure; Cardiotonic Agents; Clonixin

2018

Other Studies

9 other studies available for ketamine and Nociceptive Pain

ArticleYear
Disrupted population coding in the prefrontal cortex underlies pain aversion.
    Cell reports, 2021, 11-09, Volume: 37, Issue:6

    Topics: Animals; Aversive Agents; Excitatory Amino Acid Antagonists; Inflammation; Ketamine; Male; Neural Pa

2021
Efficacy of multimodal analgesic treatment of severe traumatic acute pain in mice pretreated with chronic high dose of buprenorphine inducing mechanical allodynia.
    European journal of pharmacology, 2020, May-15, Volume: 875

    Topics: Acute Pain; Analgesics; Animals; Buprenorphine; Dose-Response Relationship, Drug; Drug Therapy, Comb

2020
Interactions of (2S,6S;2R,6R)-Hydroxynorketamine, a Secondary Metabolite of (R,S)-Ketamine, with Morphine.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:5

    Topics: Analgesics, Opioid; Anesthetics, Dissociative; Animals; Behavior, Animal; Brain; Disease Models, Ani

2018
Clinical Pharmacology Considerations in Pain Management in Patients with Advanced Kidney Failure.
    Clinical journal of the American Society of Nephrology : CJASN, 2019, 06-07, Volume: 14, Issue:6

    Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Chronic Pain

2019
Antinociceptive and antidepressive efficacies of the combined ineffective doses of S-ketamine and URB597.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:11

    Topics: Amidohydrolases; Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Carbamate

2019
Can the LANSS scale be used to classify pain in chronic cancer pain trials?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013, Volume: 21, Issue:12

    Topics: Aged; Analgesics; Female; Humans; Ketamine; Male; Middle Aged; Neoplasms; Neuralgia; Nociceptive Pai

2013
Central antinociception induced by ketamine is mediated by endogenous opioids and μ- and δ-opioid receptors.
    Brain research, 2014, May-08, Volume: 1562

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Cinnamates; Dose-Response Relationship, Drug; Enzyme In

2014
The effects of low-dose ketamine on the analgesia nociception index (ANI) measured with the novel PhysioDoloris™ analgesia monitor: a pilot study.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:2

    Topics: Algorithms; Dose-Response Relationship, Drug; Electrocardiography; Equipment Design; Equipment Failu

2015
Pain management after traumatic spinal cord injury.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:4

    Topics: Adult; Analgesics; Anesthetics, Local; Dose-Response Relationship, Drug; Follow-Up Studies; Humans;

2012