ketamine has been researched along with Neurodegenerative Diseases in 12 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Rook, Y | 1 |
| Schmidtke, KU | 1 |
| Gaube, F | 1 |
| Schepmann, D | 1 |
| Wünsch, B | 1 |
| Heilmann, J | 1 |
| Lehmann, J | 1 |
| Winckler, T | 1 |
| Huang, TL | 1 |
| Mayence, A | 1 |
| Vanden Eynde, JJ | 1 |
| Gold, ND | 1 |
| Mallard, AJ | 1 |
| Hermann, JC | 1 |
| Zeifman, RJ | 1 |
| Pagni, BA | 1 |
| Bogenschutz, MP | 1 |
| Ross, S | 1 |
| Venkataramaiah, C | 1 |
| Lakshmi Priya, B | 1 |
| Rajendra, W | 1 |
| Koo, E | 1 |
| Oshodi, T | 1 |
| Meschter, C | 1 |
| Ebrahimnejad, A | 1 |
| Dong, G | 1 |
| Yan, J | 1 |
| Huang, Y | 1 |
| Lu, Y | 1 |
| Chen, J | 1 |
| Jiang, H | 1 |
| Xu, K | 1 |
| Lipsky, RH | 1 |
| Ribeiro, PO | 1 |
| Valentim, AM | 1 |
| Rodrigues, P | 1 |
| Olsson, IA | 1 |
| Antunes, LM | 1 |
| Huang, L | 1 |
| Liu, Y | 1 |
| Jin, W | 1 |
| Ji, X | 1 |
| Dong, Z | 1 |
| Fredriksson, A | 1 |
| Pontén, E | 1 |
| Gordh, T | 1 |
| Eriksson, P | 1 |
| Tsai, GE | 1 |
| Brunson, KL | 1 |
| Khanna, A | 1 |
| Cromwell, HC | 1 |
| Cohen, RW | 1 |
3 reviews available for ketamine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Some non-conventional biomolecular targets for diamidines. A short survey.
Topics: Amidines; Animals; Diabetes Mellitus, Type 2; DNA; Enzymes; Humans; Hypertension; Ion Channels; Myot | 2014 |
Exploring the Potential Utility of Psychedelic Therapy for Patients With Amyotrophic Lateral Sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Hallucinogens; Humans; Ketamine; Motor Neuron Disease; Neurodegenerat | 2023 |
Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans.
Topics: Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genetic Predisposition to Disease; Hu | 2015 |
9 other studies available for ketamine and Neurodegenerative Diseases
| Article | Year |
|---|---|
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
Topics: Alzheimer Disease; Butyrylcholinesterase; Carbolines; Cholinesterase Inhibitors; Excitatory Amino Ac | 2010 |
Perturbations in the catecholamine metabolism and protective effect of "3-(3, 4-dimethoxy phenyl)-1-4(methoxy phenyl) prop-2-en-1-one" during ketamine-induced schizophrenia: an
Topics: Computer Simulation; Dopamine; Humans; Ketamine; Neurodegenerative Diseases; Schizophrenia | 2021 |
Neurotoxic effects of dexmedetomidine in fetal cynomolgus monkey brains.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Brain; Caspase 3; Dexmedetomidine; Dose-Re | 2014 |
Repeated administration of ketamine can induce hippocampal neurodegeneration and long-term cognitive impairment via the ROS/HIF-1α pathway in developing rats.
Topics: Analgesics; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium Channel Blockers; Carni | 2014 |
Apoptotic neurodegeneration and spatial memory are not affected by sedative and anaesthetics doses of ketamine/medetomidine combinations in adult mice.
Topics: Anesthetics, Combined; Anesthetics, Dissociative; Animals; Apoptosis; Behavior, Animal; Brain; Disea | 2012 |
Ketamine potentiates hippocampal neurodegeneration and persistent learning and memory impairment through the PKCγ-ERK signaling pathway in the developing brain.
Topics: Analgesics; Analysis of Variance; Animals; Animals, Newborn; Brain; Disease Models, Animal; Enzyme I | 2012 |
Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Animals, Newborn; Anti-Anxiety | 2007 |
Searching for rational anti N-methyl-D-aspartate treatment for depression.
Topics: Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Met | 2007 |
Effect of the noncompetitive NMDA antagonists MK-801 and ketamine on the spastic Han-Wistar mutant: a rat model of excitotoxicity.
Topics: Animals; Cell Survival; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippo | 2001 |