Page last updated: 2024-10-29

ketamine and Myoclonic Jerk

ketamine has been researched along with Myoclonic Jerk in 7 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"We report the successful use of low-dose ketamine infusion for treating a severe episode of painful myoclonus in the lower extremities, associated with opioid-induced hyperalgesia (OIH), in a patient who was receiving long-term, high dose intrathecal hydromorphone therapy."3.78Successful reversal of hyperalgesia/myoclonus complex with low-dose ketamine infusion. ( Chan, PS; Forero, M; Restrepo-Garces, CE, 2012)
"The incidence and severity of myoclonus were assessed for 2 minutes after administration of etomidate."2.82Low-Dose Ketamine Pretreatment Reduces the Incidence and Severity of Myoclonus Induced by Etomidate: A Randomized, Double-Blinded, Controlled Clinical Trial. ( Liu, FF; Wu, GN; Wu, X; Xu, HJ; Zhou, H, 2016)
"Ketamine was associated with vomiting (14."2.68Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures. ( Barst, SM; McDowall, RH; Scher, CS, 1995)
"at pressure only prevented tremor and myoclonus at 'anaesthetizing' concentrations."1.28The effects of non-competitive NMDA receptor antagonists on rats exposed to hyperbaric pressure. ( Wann, KT; Wardley-Smith, B, 1989)
"The "spontaneous" myoclonus which followed vermisectomy (MV) was "massive", but involved firstly the trunk and secondarily the face and limbs; no ECoG paraoxysm accompanied this myoclonus, but we observed a parietal evoked potential of small amplitude, 10--15 msec after its onset."1.26Myoclonus developing after vermisectomy in photosensitive Papio papio. ( Brailowsky, S; Menini, C; Naquet, R, 1978)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, GN1
Xu, HJ1
Liu, FF1
Wu, X1
Zhou, H1
Forero, M1
Chan, PS1
Restrepo-Garces, CE1
Guler, A1
Satilmis, T1
Akinci, SB1
Celebioglu, B1
Kanbak, M1
Burrows, FA1
Seeman, RG1
McDowall, RH1
Scher, CS1
Barst, SM1
Brailowsky, S1
Menini, C1
Naquet, R1
Wardley-Smith, B1
Wann, KT1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus[NCT04921046]Phase 4224 participants (Actual)Interventional2015-01-01Completed
Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia: Pretreatment With Low-dose Ketamine Can Reduce the Dose of Etomidate. A Randomized Clinical Trial.[NCT04857450]60 participants (Anticipated)Interventional2020-11-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for ketamine and Myoclonic Jerk

ArticleYear
Low-Dose Ketamine Pretreatment Reduces the Incidence and Severity of Myoclonus Induced by Etomidate: A Randomized, Double-Blinded, Controlled Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; D

2016
Low-Dose Ketamine Pretreatment Reduces the Incidence and Severity of Myoclonus Induced by Etomidate: A Randomized, Double-Blinded, Controlled Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; D

2016
Low-Dose Ketamine Pretreatment Reduces the Incidence and Severity of Myoclonus Induced by Etomidate: A Randomized, Double-Blinded, Controlled Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; D

2016
Low-Dose Ketamine Pretreatment Reduces the Incidence and Severity of Myoclonus Induced by Etomidate: A Randomized, Double-Blinded, Controlled Clinical Trial.
    Medicine, 2016, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; D

2016
Magnesium sulfate pretreatment reduces myoclonus after etomidate.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Anticonvulsants; Depression, Chemical; Dou

2005
Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures.
    Journal of clinical anesthesia, 1995, Volume: 7, Issue:4

    Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Child; Child, Preschool; Etomid

1995

Other Studies

4 other studies available for ketamine and Myoclonic Jerk

ArticleYear
Successful reversal of hyperalgesia/myoclonus complex with low-dose ketamine infusion.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:2

    Topics: Analgesics, Opioid; Humans; Hydromorphone; Hyperalgesia; Infusions, Intravenous; Ketamine; Male; Mid

2012
Ketamine and myoclonic encephalopathy of infants (Kinsbourne syndrome).
    Anesthesia and analgesia, 1982, Volume: 61, Issue:10

    Topics: Anesthesia; Brain Diseases; Humans; Infant; Infant, Newborn; Ketamine; Male; Myoclonus; Syndrome; Th

1982
Myoclonus developing after vermisectomy in photosensitive Papio papio.
    Electroencephalography and clinical neurophysiology, 1978, Volume: 45, Issue:1

    Topics: Animals; Cerebellum; Diazepam; Disease Models, Animal; Electroencephalography; Haplorhini; Ketamine;

1978
The effects of non-competitive NMDA receptor antagonists on rats exposed to hyperbaric pressure.
    European journal of pharmacology, 1989, Jun-08, Volume: 165, Issue:1

    Topics: Animals; Binding, Competitive; Dibenzocycloheptenes; Dizocilpine Maleate; Hyperbaric Oxygenation; Ke

1989