ketamine has been researched along with Myocardial Ischemia in 11 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have investigated the effects of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate (MK801), a non-competitive N-methyl-D-aspartate (NMDA) ionotropic excitatory amino acid receptor antagonist, and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), a non-NMDA ionotropic excitatory amino acid receptor antagonist, ketamine and memantine, NMDA receptor channel blockers, on ventricular arrhythmias induced by myocardial ischaemia and myocardial ischaemia-reperfusion." | 3.70 | Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists. ( D'Amico, M; Di Filippo, C; Rossi, F, 1999) |
| "In this study, we demonstrated stereoselective differences in the biologic action of the two ketamine isomers in an animal model of myocardial ischemia." | 3.70 | S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts. ( Becker, BF; Conzen, PF; Heindl, B; Szekely, A; Zahler, S, 1999) |
| "Ketamine is a dissociative anesthetic agent that has an increased frequency of usage in the last years particularly in emergency departments." | 1.42 | Ketamine may be related to minor troponin elevations in children undergoing minor procedures in the ED. ( Eken, C; Serinken, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Serinken, M | 1 |
| Eken, C | 1 |
| Jakobsen, CJ | 1 |
| Torp, P | 1 |
| Vester, AE | 1 |
| Folkersen, L | 1 |
| Thougaard, A | 1 |
| Sloth, E | 1 |
| Ferrera, R | 1 |
| Michel, P | 1 |
| Luo, B | 1 |
| Xiang, L | 1 |
| Jiang, DH | 1 |
| Kong, XP | 1 |
| Zhang, NP | 1 |
| He, Y | 1 |
| Zhang, B | 1 |
| Yang, Y | 1 |
| Cheng, LX | 1 |
| Walsh, RS | 1 |
| Tsuchida, A | 1 |
| Daly, JJ | 1 |
| Thornton, JD | 1 |
| Cohen, MV | 1 |
| Downey, JM | 1 |
| Haessler, R | 1 |
| Kuzume, K | 1 |
| Chien, GL | 1 |
| Wolff, RA | 1 |
| Davis, RF | 1 |
| Van Winkle, DM | 1 |
| Morita, Y | 1 |
| Murakami, T | 1 |
| Iwase, T | 1 |
| Nagai, K | 1 |
| Nawada, R | 1 |
| Kouchi, I | 1 |
| Akao, M | 1 |
| Sasayama, S | 1 |
| D'Amico, M | 1 |
| Di Filippo, C | 1 |
| Rossi, F | 2 |
| Szekely, A | 1 |
| Heindl, B | 1 |
| Zahler, S | 1 |
| Conzen, PF | 1 |
| Becker, BF | 1 |
| Kitagawa, H | 2 |
| Yamazaki, T | 2 |
| Akiyama, T | 2 |
| Mori, H | 2 |
| Sunagawa, K | 2 |
| Yahagi, N | 1 |
| Kawada, T | 1 |
11 other studies available for ketamine and Myocardial Ischemia
| Article | Year |
|---|---|
Ketamine may be related to minor troponin elevations in children undergoing minor procedures in the ED.
Topics: Anesthetics, Dissociative; Child, Preschool; Conscious Sedation; Electrocardiography; Emergency Serv | 2015 |
Ketamine reduce left ventricular systolic and diastolic function in patients with ischaemic heart disease.
Topics: Aged; Diastole; Humans; Ketamine; Male; Middle Aged; Myocardial Ischemia; Prospective Studies; Systo | 2010 |
Protection of the ischemic heart during reperfusion: role of the low flow to avoid calcium overload into the myocardium in a pig model.
Topics: Animals; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Heart Arrest; Ketamine; | 2002 |
[Improved method of acute myocardial ischemic rat model].
Topics: Acute Disease; Anesthesia, General; Animals; Coronary Vessels; Disease Models, Animal; Intubation, I | 2006 |
Ketamine-xylazine anaesthesia permits a KATP channel antagonist to attenuate preconditioning in rabbit myocardium.
Topics: Animals; Glyburide; Guanidines; Ketamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Pi | 1994 |
Anaesthetics alter the magnitude of infarct limitation by ischaemic preconditioning.
Topics: Anesthetics; Animals; Blood Glucose; Constriction; Coronary Vessels; Heart; Isoflurane; Ketamine; My | 1994 |
K(ATP) channels contribute to the cardioprotection of preconditioning independent of anaesthetics in rabbit hearts.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Anesthetics; Animals; Cardiotonic Agents; Female; Hemodyn | 1997 |
Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arrhythmias, Cardiac; Blood Pressure; Dizocilpine Mal | 1999 |
S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts.
Topics: Anesthetics, Dissociative; Animals; Cell Adhesion; Coronary Vessels; Guinea Pigs; Humans; Ketamine; | 1999 |
Effects of ketamine on in vivo cardiac sympathetic nerve endings.
Topics: Animals; Cats; Coronary Disease; Dialysis; Dialysis Solutions; Excitatory Amino Acid Agonists; Femal | 2001 |
Modulatory effects of ketamine on catecholamine efflux from in vivo cardiac sympathetic nerve endings in cats.
Topics: Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Catecholamines; Cats; Coronary Arte | 2002 |