Page last updated: 2024-10-29

ketamine and Myelopathy

ketamine has been researched along with Myelopathy in 10 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"This 60-year-old man with cervical spondylosis experienced bilateral arm pain and weakness."5.36[Ketamine treatment for severe neuropathic pain with cervical spondylotic myelopathy. A case report]. ( Hamauchi, S; Isobe, M; Isu, T; Kim, K; Kyongsong, K; Matsumoto, R; Morimoto, D; Shimoda, Y, 2010)
"This 60-year-old man with cervical spondylosis experienced bilateral arm pain and weakness."1.36[Ketamine treatment for severe neuropathic pain with cervical spondylotic myelopathy. A case report]. ( Hamauchi, S; Isobe, M; Isu, T; Kim, K; Kyongsong, K; Matsumoto, R; Morimoto, D; Shimoda, Y, 2010)
"The authors conclude that repeated intrathecal administration of preservative-free S(+)-ketamine in a clinically relevant concentration and dosage has, considering the extent and severity of the lesions, a toxic effect on the central nervous system of rabbits."1.33Severe toxic damage to the rabbit spinal cord after intrathecal administration of preservative-free S(+)-ketamine. ( de Haan, P; Dijkgraaf, MG; Hollmann, MW; Pennings, FA; Troost, D; van der Vegt, MH; Vranken, JH, 2006)
" The rationale for this treatment, along with dosing guidelines and possible drawbacks, is discussed."1.32Ketamine patient-controlled analgesia for dysesthetic central pain. ( Cohen, SP; DeJesus, M, 2004)
"Ketamine has been reported to have little effect on MEPs but may produce adverse effects such as psychedelic effect and hypertension."1.31Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials. ( Furuya, H; Inoue, S; Kakimoto, M; Kawaguchi, M; Morimoto, T; Sakaki, T; Sakamoto, T, 2000)
"Ketamine is an injectable anesthetic induction agent that has been reported to have analgesic activity in pain from a variety of mechanisms, but predominantly in neuralgic and dysesthetic neuropathic pain."1.30Analgesic effect of oral ketamine in chronic neuropathic pain of spinal origin: a case report. ( Fisher, K; Hagen, NA, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamauchi, S1
Kim, K1
Kyongsong, K1
Morimoto, D1
Isu, T1
Shimoda, Y1
Matsumoto, R1
Isobe, M1
Cohen, SP1
DeJesus, M1
Prommer, E1
Vranken, JH1
Troost, D1
de Haan, P2
Pennings, FA1
van der Vegt, MH1
Dijkgraaf, MG1
Hollmann, MW1
Malinovsky, JM1
Lepage, JY1
Cozian, A1
Mussini, JM1
Pinaudt, M1
Souron, R1
Karpinski, N1
Dunn, J1
Hansen, L1
Masliah, E1
Kalkman, CJ1
Vanicky, I1
Jacobs, MJ1
Drummond, JC1
Fisher, K1
Hagen, NA1
Errando, CL1
Kawaguchi, M1
Sakamoto, T1
Inoue, S1
Kakimoto, M1
Furuya, H1
Morimoto, T1
Sakaki, T1

Other Studies

10 other studies available for ketamine and Myelopathy

ArticleYear
[Ketamine treatment for severe neuropathic pain with cervical spondylotic myelopathy. A case report].
    No shinkei geka. Neurological surgery, 2010, Volume: 38, Issue:12

    Topics: Humans; Ketamine; Male; Middle Aged; Neuralgia; Spinal Cord Diseases; Spondylosis

2010
Ketamine patient-controlled analgesia for dysesthetic central pain.
    Spinal cord, 2004, Volume: 42, Issue:7

    Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Female; Humans; Infusions, Intravenous; Ketamine;

2004
Ketamine and HTLV-1 myelopathy: NMDA blockade and immunomodulation?
    Journal of pain and symptom management, 2006, Volume: 31, Issue:5

    Topics: Excitatory Amino Acid Antagonists; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Immunolo

2006
Severe toxic damage to the rabbit spinal cord after intrathecal administration of preservative-free S(+)-ketamine.
    Anesthesiology, 2006, Volume: 105, Issue:4

    Topics: Anesthesia, Spinal; Anesthetics, Dissociative; Animals; Excitatory Amino Acid Antagonists; Female; I

2006
Is ketamine or its preservative responsible for neurotoxicity in the rabbit?
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Animals; Chlorobutanol; Injections, Spinal; Ketamine; Preservatives, Pharmaceutical; Rabbits; Spinal

1993
Subpial vacuolar myelopathy after intrathecal ketamine: report of a case.
    Pain, 1997, Volume: 73, Issue:1

    Topics: Anesthetics, Intravenous; Carcinoid Tumor; Chronic Disease; Fatal Outcome; Humans; Injections, Spina

1997
Effect of mild hypothermia and the 21-aminosteroid U-74389G on neurologic and histopathologic outcome after transient spinal cord ischemia in the rabbit.
    Journal of neurosurgical anesthesiology, 1998, Volume: 10, Issue:2

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Body Temperature; Bo

1998
Analgesic effect of oral ketamine in chronic neuropathic pain of spinal origin: a case report.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:1

    Topics: Administration, Oral; Adult; Analgesics; Chronic Disease; Humans; Ketamine; Male; Neuralgia; Spinal

1999
Spinal toxicity of drugs: some specifications about ketamine.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:1

    Topics: Anesthetics, Dissociative; Animals; Injections, Spinal; Ketamine; Spinal Cord Diseases; Swine

2000
Low dose propofol as a supplement to ketamine-based anesthesia during intraoperative monitoring of motor-evoked potentials.
    Spine, 2000, Apr-15, Volume: 25, Issue:8

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Bra

2000