ketamine has been researched along with Musculoskeletal Pain in 4 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Musculoskeletal Pain: Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ketamine has potential advantages over morphine for musculoskeletal pain relief." | 9.51 | Non-inferiority of intranasal ketamine compared to intravenous morphine for musculoskeletal pain relief among older adults in an emergency department: a randomised controlled trial. ( Paksophis, T; Sri-On, J; Thong-On, K; Tongbua, S, 2022) |
| "The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain." | 9.51 | Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022) |
| "ketamine has potential advantages over morphine for musculoskeletal pain relief." | 5.51 | Non-inferiority of intranasal ketamine compared to intravenous morphine for musculoskeletal pain relief among older adults in an emergency department: a randomised controlled trial. ( Paksophis, T; Sri-On, J; Thong-On, K; Tongbua, S, 2022) |
| "The purpose of this study is to investigate if an orally administered combination of aspirin and ketamine will provide better analgesia than a ketamine alone in adult patients presenting to the Emergency Department (ED) with acute musculoskeletal pain." | 5.51 | Oral Aspirin/ketamine versus oral ketamine for emergency department patients with acute musculoskeletal pain. ( Barberan, C; Correa Bravo, S; Davis, A; Drapkin, J; Fassassi, C; Gerges, L; Gohel, A; Hossain, R; Likourezos, A; Motov, S; Niceforo, P; Silver, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tongbua, S | 1 |
| Sri-On, J | 1 |
| Thong-On, K | 1 |
| Paksophis, T | 1 |
| Davis, A | 2 |
| Fassassi, C | 2 |
| Dove, D | 1 |
| Drapkin, J | 2 |
| Likourezos, A | 2 |
| Gohel, A | 2 |
| Favale, P | 1 |
| Hossain, R | 2 |
| Butt, M | 1 |
| Gerges, L | 2 |
| Motov, S | 2 |
| Barberan, C | 1 |
| Correa Bravo, S | 1 |
| Silver, M | 1 |
| Niceforo, P | 1 |
| Graudins, A | 1 |
| Meek, R | 1 |
| Egerton-Warburton, D | 1 |
| Seith, R | 1 |
| Furness, T | 1 |
| Chapman, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Orally Administered VTS-K (Liquid Oral Ketamine Taken Simultaneously With VTS-Aspirin) for Pain Management of Adult ED Patients Presenting to the ED With Acute Musculoskeletal Pain[NCT04702555] | 25 participants (Actual) | Observational | 2021-01-08 | Completed | |||
| A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone in Adult Patients Presenting to the ED With Acute Musculoskeletal Pain: Prospective, Randomized, Open-Label, Clinical Trial.[NCT04860804] | Phase 4 | 60 participants (Actual) | Interventional | 2021-04-22 | Completed | ||
| Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321] | Phase 4 | 22 participants (Actual) | Interventional | 2015-05-01 | Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reduction of pain scores on numeric rating pain scale (NRS) at 60 minutes mark form the baseline. The NRS is an 11 item Likert Scale ranging from 0 (no pain) to 10 (very severe pain) with 5 indicating moderate pain. (NCT04860804)
Timeframe: 60 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| AOK Group | 2.18 |
| OK Group | 4.01 |
The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 0 |
| Fentanyl | 0 |
An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.36 |
| Fentanyl | 2.09 |
3 trials available for ketamine and Musculoskeletal Pain
1 other study available for ketamine and Musculoskeletal Pain
| Article | Year |
|---|---|
Analgesic Efficacy of Oral Aspirin/Ketamine Combination for Management of Acute Musculoskeletal Pain in the Emergency Department - A Proof of Concept Pilot Study.
Topics: Acute Pain; Adult; Analgesics; Aspirin; Double-Blind Method; Emergency Service, Hospital; Humans; Ke | 2022 |