Page last updated: 2024-10-29

ketamine and Muscle Contraction

ketamine has been researched along with Muscle Contraction in 82 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Neostigmine causes airway smooth muscle contraction through the direct stimulation of muscarinic receptors and the activation of phosphatidylinositol (PI) responses."3.72Effects of ketamine on neostigmine-induced contractile and phosphatidylinositol responses of the rat trachea. ( Makita, T; Miyoshi, H; Saito, M; Shibata, O; Sumikawa, K; Yamaguchi, M, 2003)
"Pain was analyzed in patients with fibromyalgia (FM) in a randomized, double blind, crossover study using intravenous (i."2.68Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs. ( Ahlner, J; Bengtsson, A; Bengtsson, M; Ekselius, L; Henriksson, KG; Sörensen, J, 1997)
"The dose-response curves of vecuronium and pancuronium were compared during ketamine anaesthesia in 60 patients (ASA I)."2.65Dose-response relationships and neuromuscular blocking effects of vecuronium pancuronium during ketamine anaesthesia. ( Engbaek, J; Ording, H; Pedersen, T; Viby-Mogensen, J, 1984)
"Ketamine, which is a general anaesthetic that induces a dissociative anaesthesia, acts by blocking the N-methyl-D-aspartate receptor (NMDAr) in the brain."1.35The vasodilatory effect of ketamine is independent of the N-methyl-D-aspartate receptor: lack of functional N-methyl-D-aspartate receptors in rat mesenteric artery smooth muscle. ( Bae, YM; Cho, SI; Kim, B; Kim, JG; Kim, SH; Kim, YS; Noh, HJ; Park, SH; Woo, NS, 2009)
"1."1.30Stereospecific effects of ketamine enantiomers on canine tracheal smooth muscle. ( Jones, KA; Lindahl, SG; Pabelick, CM; Rehder, K; Shumway, R; Warner, DO, 1997)
" Ketamine-fentanyl-propofol combination at a dosage of 30-0."1.29Comparison of anesthesia induced by ketamine-fentanyl combination and maintained by propofol or etomidate in New Zealand white rabbits. ( Griffith, JW; Lang, CM; Luo, Y; Russell, GB, 1995)
"The fall in the time tension index as respiratory failure approached was due primarily to a fall in inspiratory time and duty cycle."1.29Respiratory failure due to altered central drive during inspiratory loading in rabbits. ( Ferguson, GT, 1995)
"Ketamine is a potent bronchodilator, but its mode of action is unclear."1.29Mechanisms of the relaxant action of ketamine on isolated porcine trachealis muscle. ( Hatch, DJ; Rehder, K; Wilson, LE, 1993)
" With increasing ketamine concentration (5 x 10(-5)-10(-3) mol l-1), the amplitude of glutamate potentials was reduced and dose-response curves for ionophoresis of L-glutamate were shifted to the right, particularly after concanavalin A treatment."1.28Enhancement of desensitization of quisqualate-type glutamate receptor by the dissociative anaesthetic ketamine. ( Ashford, ML; Boden, P; Ramsey, RL; Usherwood, PN, 1989)
" Ketamine, 3 X 10(-4) M, produced a shift to the right of the dose-response curve without altering the maximum contractile responses to carbachol, but had no effect on dose-response curves to substance P, the putative noncholinergic transmitter in these bronchial segments."1.27Differential effect of ketamine on cholinergic- and noncholinergic-induced contractions of isolated guinea-pig bronchi. ( Brunson, DB; Buckner, CK; Laravuso, RB; Leblanc, PH; Will, JA, 1987)

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-199046 (56.10)18.7374
1990's28 (34.15)18.2507
2000's4 (4.88)29.6817
2010's3 (3.66)24.3611
2020's1 (1.22)2.80

Authors

AuthorsStudies
Yang, SS1
Chang, HH1
Chang, SJ1
Tang, HC1
Lam, WP1
Zhang, X1
Leung, PC1
Yew, DT1
Liang, W1
Keshtgar, AS1
Choudhry, MS1
Kufeji, D1
Ward, HC1
Clayden, GS1
Noh, HJ1
Bae, YM1
Park, SH1
Kim, JG1
Kim, B1
Kim, YS1
Kim, SH1
Cho, SI1
Woo, NS1
Toyosato, A1
Begum, M1
Sugiyama, K1
Someya, G1
Saito, M2
Shibata, O3
Yamaguchi, M2
Miyoshi, H1
Makita, T3
Sumikawa, K3
Kevin, LG1
Yoshimura, M1
Nishioka, K1
Little, HJ1
Alexander, KL1
Gargan, MF1
Widdison, AL1
Engbaek, J1
Ording, H1
Pedersen, T1
Viby-Mogensen, J1
Mahmoodi, V1
Byrne, AJ1
Healy, TE1
Hussain, SZ1
Finck, AD1
Ngai, SH1
Smith, DJ1
Westfall, DP1
Adams, JD1
Savage, AO1
Sanya, IO1
Rydqvist, B1
Faijerson, B1
Marwaha, J1
Maleque, MA1
Warnick, JE1
Albuquerque, EX1
Juang, MS1
Yonemura, K1
Morioka, T1
Tanaka, I1
Lundy, PM4
Frew, R3
Altura, BM1
Altura, BT1
Carella, A1
Hirota, K4
Zsigmond, EK5
Matsuki, A5
Rabito, SF5
Luo, Y1
Russell, GB1
Griffith, JW1
Lang, CM1
Miyawaki, I1
Nakamura, K1
Terasako, K1
Toda, H1
Kakuyama, M1
Mori, K1
Hodgson, PE1
Rehder, K3
Hatch, DJ2
Ratz, PH1
Callahan, PE1
Lattanzio, FA1
Ferguson, GT1
Richard, BM1
Donaldson, MD1
Kounenis, G1
Koutsoviti-Papadopoulou, M1
Elezoglou, V1
Krissel, J1
Dick, WF1
Leyser, KH1
Gervais, H1
Brockerhoff, P1
Schranz, D1
Wilson, LE1
Abdalla, SS1
Laravuso, RB2
Will, JA2
Kanmura, Y2
Kajikuri, J1
Itoh, T1
Yoshitake, J2
Hildebrand, SV1
Hill, T1
Sato, T4
Hustveit, O1
Maurset, A1
Oye, I1
Sakube, Y1
Ando, H1
Kagawa, H1
Tsujita, T1
Iwanaga, S1
Nakamura, H1
Fukusaki, M1
Pabelick, CM1
Jones, KA1
Shumway, R1
Lindahl, SG1
Warner, DO1
Sörensen, J1
Bengtsson, A1
Ahlner, J1
Henriksson, KG1
Ekselius, L1
Bengtsson, M1
Lapointe, BM1
Côté, CH1
Barmack, NH1
Clanachan, AS2
McGrath, JC2
Rossi, G1
Poggiali, C1
Gowdey, CW2
Colhoun, EH2
Coughlan, MG1
Flynn, NM1
Kenny, D1
Warltier, DC1
Kampine, JP1
Marco, LA2
Joshi, RS1
Cepeda, NJ1
Rhyne, DB1
Ulker, S1
Tok, D1
Kosay, S1
Oyman, S1
Kang, BS1
Lee, YH1
Nam, TS1
Yeon, DS1
Hwang, SK1
Park, KS1
Wong, KK1
Leblanc, PH1
Buckner, CK1
Brunson, DB1
Ashford, ML1
Boden, P1
Ramsey, RL1
Usherwood, PN1
Hackl, W1
Winkler, M1
Mauritz, W1
Steinbereithner, K1
Tsai, SK1
Lee, CM1
Tran, B1
Thor, KB1
Blais, DP1
de Groat, WC1
Casteels, R1
Reed, TF1
Aldes, LD1
Chronister, RB1
Brown, CB1
White, LE1
Yamazaki, M1
Ito, Y1
Momose, Y1
Clinton, ME1
Misulis, KE1
Dettbarn, WD1
Baneux, PJ1
Garner, D1
McIntyre, HB1
Holshuh, HJ1
Gverzdys, S1
Lockwood, PA1
Thompson, G1
Bogdan, LG1
Glisson, SN1
El-Etr, AA1
Tang, AH1
Schroeder, LA1
Gergis, SD1
Dretchen, KL1
Sokoll, MD1
Long, JP1
Schöning, B1
von Bazan, UB1
Koch, H1
Lundy, P1
Foti, F1
Gal, TJ1
Malit, LA1
Kumazawa, T2
Kanda, F2
Yasuda, K2
Sawa, T1
Sunamori, M1
Oliver, JE1
Young, WO1
Santafé, J1
Ortis, J1
Vila, J1
Segarra-Doménech, J1
Espluges, J1
Nedergaard, OA1
Ishikawa, M1
Shimizu, T1
Matsuda, S1
Yamanaka, I1
Dowdy, EG1
Freuchen, I1
Ostergård, J1
Dalsgård, M1
Thorshauge, C1
Maritano, M1
Zaccagna, CA1
Vergano, F1
Musto, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Naloxone Block of Low-dose (Analgetic Dose) Ketamine[NCT00921765]Phase 43 participants (Actual)Interventional2009-12-31Terminated (stopped due to Problems with patient recruitment)
Nitrous Oxide as Treatment for Fibromyalgia[NCT05357066]Phase 250 participants (Anticipated)Interventional2021-11-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for ketamine and Muscle Contraction

ArticleYear
Modulation of exteroceptive suppression periods in human jaw-closing muscles by subanaesthetic dose of propofol.
    Journal of oral rehabilitation, 2011, Volume: 38, Issue:2

    Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Bite Force; Dose-Response Relationship, Drug;

2011
Dose-response relationships and neuromuscular blocking effects of vecuronium pancuronium during ketamine anaesthesia.
    British journal of anaesthesia, 1984, Volume: 56, Issue:9

    Topics: Adult; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Female; Humans; Ketamine; Muscle C

1984
Thiopentone, thiopentone/ketamine, and ketamine for induction of anaesthesia in caesarean section.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apgar Score; Arrhythmias, Cardiac; Awarenes

1994
Fibromyalgia--are there different mechanisms in the processing of pain? A double blind crossover comparison of analgesic drugs.
    The Journal of rheumatology, 1997, Volume: 24, Issue:8

    Topics: Adult; Anesthetics, Dissociative; Area Under Curve; Cross-Over Studies; Double-Blind Method; Drug Th

1997
[Ketamine and diazepam for anaesthesia in infantile cerebral palsy (author's transl)].
    Der Anaesthesist, 1974, Volume: 23, Issue:1

    Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Dissociative; Cerebral Palsy; Child; Child, Presch

1974
[Clinical report on Ketalar (CI-581)].
    Minerva anestesiologica, 1972, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Blood Pressure; Chemical Phenomena; Chemistry; Child; Ch

1972
The influence of ketamine induction on potassium changes and fasciculations following suxamethonium.
    British journal of anaesthesia, 1972, Volume: 44, Issue:10

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Blood; Blood Glucose; Carbon Dioxide; Colorimetry; Hum

1972

Other Studies

75 other studies available for ketamine and Muscle Contraction

ArticleYear
Does ketamine ameliorate the social stress-related bladder dysfunction in mice?
    Neurourology and urodynamics, 2020, Volume: 39, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice;

2020
Chronic ketamine treatment-induced changes in contractility characteristics of the mouse detrusor.
    International urology and nephrology, 2014, Volume: 46, Issue:8

    Topics: Analgesics; Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Ketamine; Male; Mice; Mic

2014
Anorectal manometry with and without ketamine for evaluation of defecation disorders in children.
    Journal of pediatric surgery, 2015, Volume: 50, Issue:3

    Topics: Adolescent; Anal Canal; Analgesics; Biofeedback, Psychology; Child; Child, Preschool; Constipation;

2015
The vasodilatory effect of ketamine is independent of the N-methyl-D-aspartate receptor: lack of functional N-methyl-D-aspartate receptors in rat mesenteric artery smooth muscle.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Dissociative; Animals; Excitatory Amino Acid Antagonists;

2009
Effects of ketamine on neostigmine-induced contractile and phosphatidylinositol responses of the rat trachea.
    Journal of anesthesia, 2003, Volume: 17, Issue:2

    Topics: Aluminum Compounds; Anesthetics, Intravenous; Animals; Cholinesterase Inhibitors; Dose-Response Rela

2003
Comment on "Effects of short vs. prolonged mechanical ventilation on antioxidant systems in piglet diaphragm" by Jaber et al.
    Intensive care medicine, 2006, Volume: 32, Issue:9

    Topics: Animals; Blood Gas Analysis; Blood Pressure; Diaphragm; Ketamine; Muscle Contraction; Oxidative Stre

2006
Effects of propofol and ketamine on ATP-induced contraction of the rat trachea.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Adenosine Triphosphate; Analgesics; Anesthetics, Intravenous; Animals; Binding, Competitive; Dose-Re

2007
Ketamine and the guinea-pig ileum: possible opiate agonist and antagonist actions and effects of peptidase inhibition.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:1

    Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Dose-Response Rel

1983
Effect of ketamine on transmission in sympathetic ganglia.
    British journal of anaesthesia, 1980, Volume: 52, Issue:4

    Topics: Abdominal Muscles; Animals; Anura; Carbachol; Dose-Response Relationship, Drug; Ganglia, Sympathetic

1980
Opiate receptor mediation of ketamine analgesia.
    Anesthesiology, 1982, Volume: 56, Issue:4

    Topics: Analgesics; Animals; Binding, Competitive; Brain; Dextrorphan; Etorphine; Guinea Pigs; In Vitro Tech

1982
Assessment of the potential agonistic and antagonistic properties of ketamine at opiate receptors in the guinea-pig ileum.
    Neuropharmacology, 1982, Volume: 21, Issue:7

    Topics: Acetylcholine; Animals; Electric Stimulation; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Ke

1982
Effect of ketamine on cholinergic transmission in the isolated guinea-pig ileum preparation.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 263, Issue:1

    Topics: Animals; Calcium; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques;

1983
Ketamine: effects on the mechanical properties of the frog sartorius muscle.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:1

    Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Ketamine; Muscle

1983
Some mechanisms underlying actions of ketamine on electromechanical coupling in skeletal muscle.
    Journal of neuroscience research, 1980, Volume: 5, Issue:1

    Topics: Animals; Anura; Dose-Response Relationship, Drug; Electric Stimulation; Ketamine; Membrane Potential

1980
The mechanism and site of action of ketamine on skeletal muscle.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Female; In Vitro Techniques; Ketamine; Membrane Potential

1981
Ketamine acts on the peripheral sympathetic nervous system of guinea pigs.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:1

    Topics: Animals; Electric Stimulation; Guinea Pigs; Hypogastric Plexus; Ketamine; Male; Muscle Contraction;

1980
Ketamine potentiates catecholamine responses of vascular smooth muscle by inhibition of extraneuronal uptake.
    Canadian journal of physiology and pharmacology, 1981, Volume: 59, Issue:6

    Topics: Animals; Aorta; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Ketamine; Muscle

1981
Effects of ketamine on vascular smooth muscle function.
    British journal of pharmacology, 1980, Volume: 70, Issue:2

    Topics: Animals; Aorta, Thoracic; Calcium; Drug Interactions; In Vitro Techniques; Ketamine; Male; Muscle Co

1980
Ketamine inhibits contractile responses of intestinal smooth muscle by decreasing the influx of calcium through the L-type calcium channel.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Comparison of anesthesia induced by ketamine-fentanyl combination and maintained by propofol or etomidate in New Zealand white rabbits.
    Laboratory animal science, 1995, Volume: 45, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Blood Gas Analysis; Body Temperature; Drug Combinations; Etomidate

1995
Modification of endothelium-dependent relaxation by propofol, ketamine, and midazolam.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:3

    Topics: Acetylcholine; Anesthetics, Intravenous; Animals; Binding Sites; Cyclic GMP; Endothelium, Vascular;

1995
Comparison of the pharmacodynamics of ketamine in the isolated neonatal and adult porcine airway.
    British journal of anaesthesia, 1995, Volume: 75, Issue:1

    Topics: Acetylcholine; Age Factors; Animals; Culture Techniques; Dimethylphenylpiperazinium Iodide; Dose-Res

1995
Ketamine relaxes rabbit femoral arteries by reducing [Ca2+]i and phospholipase C activity.
    European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Respiratory failure due to altered central drive during inspiratory loading in rabbits.
    Respiration physiology, 1995, Volume: 99, Issue:1

    Topics: Animals; Diaphragm; Inspiratory Capacity; Ketamine; Male; Muscle Contraction; Muscle Fatigue; Phreni

1995
Ketamine and muscle spasm.
    British journal of anaesthesia, 1994, Volume: 73, Issue:3

    Topics: Child; Humans; Ketamine; Male; Muscle Contraction; Paralysis; Peripheral Nervous System Diseases; Ra

1994
Ketamine inhibits the anticholinesterase activity of ranitidine and physostigmine.
    General pharmacology, 1994, Volume: 25, Issue:4

    Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Guinea

1994
Mechanisms of the relaxant action of ketamine on isolated porcine trachealis muscle.
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro T

1993
Mechanisms of the inhibitory effect of ketamine on guinea pig isolated main pulmonary artery.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:1

    Topics: Animals; Buffers; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Carrier Proteins; Cell Me

1994
Effects of ketamine on contraction and synthesis of inositol 1,4,5-trisphosphate in smooth muscle of the rabbit mesenteric artery.
    Anesthesiology, 1993, Volume: 79, Issue:3

    Topics: Animals; Inositol 1,4,5-Trisphosphate; Ketamine; Male; Mesenteric Arteries; Muscle Contraction; Musc

1993
Neuromuscular blockade by use of atracurium in anesthetized llamas.
    American journal of veterinary research, 1993, Volume: 54, Issue:3

    Topics: Analysis of Variance; Anesthesia, General; Animals; Atracurium; Blood Pressure; Camelids, New World;

1993
Relaxant effect of ketamine and its isomers on histamine-induced contraction of tracheal smooth muscle.
    British journal of anaesthesia, 1996, Volume: 76, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Interaction of the chiral forms of ketamine with opioid, phencyclidine, sigma and muscarinic receptors.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:6

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Binding Sites; Dose-Response Relations

1995
Ketamine relaxes airway smooth muscle contracted by endothelin.
    Anesthesia and analgesia, 1997, Volume: 84, Issue:4

    Topics: Anesthetics, Dissociative; Animals; Calcium; Calcium Channels; Carbachol; Egtazic Acid; Endothelin-1

1997
An abnormal ketamine response in mutants defective in the ryanodine receptor gene ryr-1 (unc-68) of Caenorhabditis elegans.
    Journal of molecular biology, 1997, Apr-11, Volume: 267, Issue:4

    Topics: Amino Acid Sequence; Anesthetics, Dissociative; Animals; Animals, Genetically Modified; Aspartic Aci

1997
Effects of intravenous anesthetics on the contraction and response of rat trachea to phosphatidylinositol.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:3

    Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Carbachol; Fentanyl; Ketamine; Male; Midazo

1997
Stereospecific effects of ketamine enantiomers on canine tracheal smooth muscle.
    British journal of pharmacology, 1997, Volume: 121, Issue:7

    Topics: Acetylcholine; Animals; Bronchodilator Agents; Dogs; Female; Humans; In Vitro Techniques; Ketamine;

1997
Ketamine inhibits the tonic response to carbachol and histamine in the guinea pig trachea.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:4

    Topics: Anesthetics, Dissociative; Animals; Bronchoconstrictor Agents; Buffers; Calcium; Carbachol; Chelatin

1998
The role of the N-methyl-D-aspartic acid receptor in the relaxant effect of ketamine on tracheal smooth muscle.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:6

    Topics: Animals; Bronchodilator Agents; Chlorides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fe

1998
Anesthetics can alter subsequent in vitro assessment of contractility in slow and fast skeletal muscles of rat.
    The American journal of physiology, 1999, Volume: 277, Issue:3

    Topics: Anesthetics; Animals; Female; Ketamine; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fiber

1999
Recruitment and suprathreshold frequency modulation of single extraocular muscle fibers in the rabbit.
    Journal of neurophysiology, 1977, Volume: 40, Issue:4

    Topics: Animals; Evoked Potentials; Ketamine; Motor Neurons; Muscle Contraction; Muscle Tonus; Neural Conduc

1977
Effects of ketamine on the peripheral autonomic nervous system of the rat.
    British journal of pharmacology, 1976, Volume: 58, Issue:2

    Topics: Animals; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Autonomic Nervous System

1976
[Fasciculation due to succinylcholine. Comparative statistical study between barbiturates and ketamine].
    Minerva anestesiologica, 1975, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Humans; Ketamine; Middle Aged; Muscle Contraction; Neuromuscular Jun

1975
Further experimental evidence for a smooth muscle depressant effect of ketamine.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:1

    Topics: Acetylcholine; Animals; Barium; Carbachol; Depression, Chemical; Female; Guinea Pigs; Histamine; Ile

1975
Proceedings: Effects of ketamine on the peripheral sympathetic nervous system of the rat.
    British journal of pharmacology, 1975, Volume: 55, Issue:2

    Topics: Animals; Blood Pressure; Drug Synergism; Ketamine; Muscle Contraction; Muscle, Smooth; Norepinephrin

1975
Differential relaxant effect of high concentrations of intravenous anesthetics on endothelin-constricted proximal and distal canine coronary arteries.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:3

    Topics: Anesthetics; Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelins; Female;

1992
Unitary correlates of linguo-pharyngeal events in a dyskinetic rat model.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3

    Topics: Animals; Deglutition; Dyskinesia, Drug-Induced; Electric Stimulation; Hypoglossal Nerve; Ketamine; L

1991
Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro.
    International journal of experimental pathology, 1991, Volume: 72, Issue:5

    Topics: Animals; Caffeine; Diaphragm; Drug Synergism; Female; Halothane; In Vitro Techniques; Ketamine; Male

1991
Effects of ketamine on contractile responses in vascular smooth muscle.
    Yonsei medical journal, 1990, Volume: 31, Issue:4

    Topics: Animals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug; Female; Histamine; Isometric Co

1990
Potentiated depression of indirectly evoked twitch tension of rat soleus muscle following arterial blood occlusion in the presence of ketamine.
    The Chinese journal of physiology, 1990, Volume: 33, Issue:4

    Topics: Animals; Ketamine; Male; Muscle Contraction; Muscles; Pentobarbital; Rats; Rats, Inbred Strains

1990
Differential effect of ketamine on cholinergic- and noncholinergic-induced contractions of isolated guinea-pig bronchi.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 287, Issue:1

    Topics: Animals; Bronchi; Carbachol; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ketamine; Muscl

1987
Enhancement of desensitization of quisqualate-type glutamate receptor by the dissociative anaesthetic ketamine.
    The Journal of experimental biology, 1989, Volume: 141

    Topics: Action Potentials; Animals; Concanavalin A; Dose-Response Relationship, Drug; Glutamates; Glutamic A

1989
[The action of ketamine on muscle contractile behavior. In vitro studies on the musculature of subjects susceptible to malignant hyperthermia].
    Der Anaesthesist, 1989, Volume: 38, Issue:12

    Topics: Caffeine; Disease Susceptibility; Halothane; In Vitro Techniques; Ketamine; Malignant Hyperthermia;

1989
Ketamine enhances phase I and phase II neuromuscular block of succinylcholine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:2

    Topics: Anesthesia, Inhalation; Animals; Drug Synergism; Electric Stimulation; Ketamine; Macaca; Male; Muscl

1989
Behavioral analysis of the postnatal development of micturition in kittens.
    Brain research. Developmental brain research, 1989, Mar-01, Volume: 46, Issue:1

    Topics: Animals; Cats; Female; Ketamine; Maternal Deprivation; Muscle Contraction; Reflex; Urinary Bladder;

1989
Ketamine-induced relaxation in intact and skinned smooth muscles of the rabbit ear artery.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Animals; Arteries; Caffeine; Ear; Female; In Vitro Techniques; Ketamine; Male; Muscle Contraction; M

1989
Cortical control of tongue contractility in the rat under ketamine anaesthesia.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:5

    Topics: Anesthesia; Animals; Cerebral Cortex; Electric Stimulation; Evoked Potentials; Haloperidol; Ketamine

1989
[Effects of ketamine on K+-contracture in isolated vascular smooth muscle from rabbit].
    Masui. The Japanese journal of anesthesiology, 1989, Volume: 38, Issue:6

    Topics: Animals; In Vitro Techniques; Ketamine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassiu

1989
Effects of phenytoin, ketamine, and atropine methyl nitrate in preventing neuromuscular toxicity of acetylcholinesterase inhibitors soman and diisopropylphosphorofluoridate.
    Journal of toxicology and environmental health, 1988, Volume: 24, Issue:4

    Topics: Animals; Atropine Derivatives; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate

1988
Euthanasia of rabbits by intravenous administration of ketamine.
    Journal of the American Veterinary Medical Association, 1986, Nov-01, Volume: 189, Issue:9

    Topics: Animals; Blood Pressure; Euthanasia; Female; Heart Rate; Injections, Intravenous; Ketamine; Male; Mu

1986
Ketamine: evidence of tissue specific inhibition of neuronal and extraneuronal catecholamine uptake processes.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:4

    Topics: Animals; Aorta; Epinephrine; Hydrocortisone; Hydroxydopamines; In Vitro Techniques; Ketamine; Male;

1985
Differential effects of ketamine isomers on neuronal and extraneuronal catecholamine uptake mechanisms.
    Anesthesiology, 1986, Volume: 64, Issue:3

    Topics: Animals; Aorta; Catecholamines; Cocaine; Hydrocortisone; In Vitro Techniques; Ketamine; Muscle Contr

1986
The effect of ketamine upon depolarizing and non-depolarizing neuromuscular blockade in rabbit.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:3

    Topics: Animals; Drug Interactions; Electric Stimulation; Ketamine; Male; Muscle Contraction; Neuromuscular

1974
Spinal-cord depressant effects of ketamine and etoxadrol in the cat and the rat.
    Anesthesiology, 1973, Volume: 39, Issue:1

    Topics: Abdominal Muscles; Anesthesia; Animals; Blood Pressure; Cats; Depression, Chemical; Dioxoles; Dose-R

1973
Effect of anesthetics on acetylcholine release from the myoneural junction.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Acetylcholine; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Anura; Ethyl E

1972
Pressor responses of ketamine and circulating biogenic amines.
    Nature: New biology, 1973, Jan-17, Volume: 241, Issue:107

    Topics: Animals; Aorta; Biological Assay; Blood Pressure; Catecholamines; Dogs; Heart Rate; In Vitro Techniq

1973
[Effect of various drugs on papillary muscle contraction of the right ventricle of cats. 1. Ketamine hydrochloride].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:6

    Topics: Animals; Benperidol; Cats; Fentanyl; In Vitro Techniques; Ketamine; Muscle Contraction; Papillary Mu

1972
Evaluation of pharmacologic agents for restraint in cystometry in the dog and cat.
    American journal of veterinary research, 1973, Volume: 34, Issue:5

    Topics: Acepromazine; Air; Anesthesia; Aniline Compounds; Animals; Cats; Dogs; Droperidol; Female; Fentanyl;

1973
[Action on uterine smooth muscle of a nonbarbituate intravenous anesthetic: ketamine].
    Revista espanola de anestesiologia y reanimacion, 1973, Volume: 20, Issue:2

    Topics: Anesthesia, Intravenous; Female; Humans; Injections, Intravenous; Ketamine; Muscle Contraction; Musc

1973
Cocaine-like effect of ketamine on vascular adrenergic neurones.
    European journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Animals; Aorta; Bretylium Compounds; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation

1973
The effects of obstetric anesthetic agents on the uterine contractility with special reference to intrauterine pressure.
    Acta obstetrica et gynaecologica Japonica, 1973, Volume: 20, Issue:2

    Topics: Anesthesia, Obstetrical; Female; Humans; Ketamine; Methoxyflurane; Muscle Contraction; Pregnancy; Pr

1973
The effects of ketamine on spiral-cut strips of rabbit aorta.
    Anesthesiology, 1974, Volume: 40, Issue:3

    Topics: Animals; Aorta; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Ketamin

1974
[Ketalar anesthesia--a preliminary report].
    Nordisk medicin, 1971, Dec-02, Volume: 86, Issue:48

    Topics: Adolescent; Adult; Aged; Anesthetics; Blood Pressure; Child; Cyclohexanes; Female; Humans; Ketamine;

1971
[Experience with Ketalar anesthesia].
    Nordisk medicin, 1971, Dec-02, Volume: 86, Issue:48

    Topics: Anesthetics; Blood Pressure; Child; Cyclohexanes; Cyclopropanes; Female; Halothane; Humans; Hyperten

1971
[Effect of ketamine chloride on muscle contraction of the papillary muscle of the isolated right ventricle of cats].
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:10

    Topics: Anesthetics; Animals; Cats; Cyclohexanes; Heart Ventricles; In Vitro Techniques; Ketamine; Muscle Co

1971
[Striated muscle fibers and CI-581].
    Minerva anestesiologica, 1969, Volume: 35, Issue:1

    Topics: Action Potentials; Adult; Anesthesia, Intravenous; Anesthetics; Cyclohexanes; Electromyography; Huma

1969