ketamine has been researched along with Mucositis, Oral in 5 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ketamine mouthwashes have been used for pain relief, but supporting evidence is limited." | 9.24 | Treatment of severe mucositis pain with oral ketamine mouthwash. ( Craig, M; Cumpston, A; Hamadani, M; Kanate, AS; Shillingburg, A; Wen, S, 2017) |
| " Ketamine mouthwashes have been used for pain relief, but supporting evidence is limited." | 5.24 | Treatment of severe mucositis pain with oral ketamine mouthwash. ( Craig, M; Cumpston, A; Hamadani, M; Kanate, AS; Shillingburg, A; Wen, S, 2017) |
| "Ketamine oral rinse has shown promising results in a few studies in adults." | 2.94 | Ketamine mouthwash versus placebo in the treatment of severe oral mucositis pain in children with cancer: A randomized double-blind placebo-controlled trial. ( Bakhshi, S; Gupta, AK; Meena, JP; Pandey, RM; Prakash, S; Seth, R; Velpandian, T, 2020) |
| "Pain is a significant side effect of disease, surgery and treatments including chemotherapy." | 1.43 | Pain management for chemotherapy-induced oral mucositis. ( Bennett, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prakash, S | 1 |
| Meena, JP | 1 |
| Gupta, AK | 1 |
| Bakhshi, S | 1 |
| Velpandian, T | 1 |
| Pandey, RM | 1 |
| Seth, R | 1 |
| Higgins, EA | 1 |
| West, JA | 1 |
| Bennett, M | 1 |
| Shillingburg, A | 1 |
| Kanate, AS | 1 |
| Hamadani, M | 1 |
| Wen, S | 1 |
| Craig, M | 1 |
| Cumpston, A | 1 |
| Baas, EJ | 1 |
| Potkay, S | 1 |
| Bacher, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash[NCT01566448] | Phase 2 | 30 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in pain score as reported at baseline and after the use of ketamine mouthwash on a numeric scale from 0 to 10, with 0 representing no pain and 10 representing the worst pain. (NCT01566448)
Timeframe: 1 hour after baseline
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 2 |
Sleep quality, as reported by the subject on a numeric scale (1-10) will be used as a surrogate marker of quality of life with 0 indicating no sleep and 10 indicating the best sleep you have had. (NCT01566448)
Timeframe: Day 1 after start of ketamine mouthwashes
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 1 |
Change of topical lidocaine uses in 24 hour period (NCT01566448)
Timeframe: Days 1 after start of ketamine mouthwashes
| Intervention | lidocaine doses per day (Median) |
|---|---|
| Ketamine | 1 |
Change in IV morphine equivalents of opioid requirements (NCT01566448)
Timeframe: Days 1 after start of ketamine mouthwashes
| Intervention | IV morphine equivalents (Median) |
|---|---|
| Ketamine | 12 |
1 review available for ketamine and Mucositis, Oral
| Article | Year |
|---|---|
The agouti (Dasyprocta sp) in biomedical research and captivity.
Topics: Anesthesia; Animals; Animals, Laboratory; Blood Specimen Collection; Coccidiosis; Diet; Female; Hous | 1976 |
2 trials available for ketamine and Mucositis, Oral
| Article | Year |
|---|---|
Ketamine mouthwash versus placebo in the treatment of severe oral mucositis pain in children with cancer: A randomized double-blind placebo-controlled trial.
Topics: Adolescent; Analgesics; Antineoplastic Combined Chemotherapy Protocols; Cancer Pain; Child; Double-B | 2020 |
Treatment of severe mucositis pain with oral ketamine mouthwash.
Topics: Adult; Aged; Female; Hematopoietic Stem Cell Transplantation; Humans; Ketamine; Male; Middle Aged; M | 2017 |
2 other studies available for ketamine and Mucositis, Oral
| Article | Year |
|---|---|
A Novel Use of Topical Ketamine for the Treatment of Oral Pemphigus: A Case Report.
Topics: Humans; Ketamine; Male; Middle Aged; Paraneoplastic Syndromes; Pemphigus; Stomatitis | 2021 |
Pain management for chemotherapy-induced oral mucositis.
Topics: Administration, Intravenous; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Cancer Pain; Chi | 2016 |