Page last updated: 2024-10-29

ketamine and Morphine Abuse

ketamine has been researched along with Morphine Abuse in 7 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Ketamine could suppress not only the place preference but also the phosphorylation of CREB produced by morphine, F9202 and F9204."1.32Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm. ( Che, LW; Chen, J; Chi, ZQ; Gao, C; Xu, XJ, 2003)
"Morphine was administered in a single dose (300 mg/kg) of a slow release preparation."1.30Decrease of tolerance to, and physical dependence on morphine by, glutamate receptor antagonists. ( Cabello, P; Contreras, E; Germany, A; González, P; Norris, B, 1997)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Witkin, JM1
Kranzler, J1
Kaniecki, K1
Popik, P1
Smith, JL1
Hashimoto, K1
Sporn, J1
Hales, TG1
Gao, C1
Che, LW1
Chen, J1
Xu, XJ1
Chi, ZQ1
Narita, M1
Kato, H1
Miyoshi, K1
Aoki, T1
Yajima, Y1
Suzuki, T1
González, P1
Cabello, P1
Germany, A1
Norris, B1
Contreras, E1
Streel, E1
Dan, B1
Bredas, P1
Clement, B1
Pelc, I1
Verbanck, P1
Koyuncuoğlu, H1
Dizdar, Y1
Aricioğlu, F1
Sayin, U1

Reviews

1 review available for ketamine and Morphine Abuse

ArticleYear
Treatment for psychological dependence on morphine: usefulness of inhibiting NMDA receptor and its associated protein kinase in the nucleus accumbens.
    Life sciences, 2005, Sep-16, Volume: 77, Issue:18

    Topics: Animals; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Huma

2005

Other Studies

6 other studies available for ketamine and Morphine Abuse

ArticleYear
R-(-)-ketamine modifies behavioral effects of morphine predicting efficacy as a novel therapy for opioid use disorder
    Pharmacology, biochemistry, and behavior, 2020, Volume: 194

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Humans; Ketami

2020
Arresting the development of morphine tolerance and dependence.
    British journal of anaesthesia, 2011, Volume: 107, Issue:5

    Topics: Analgesics; Animals; Drug Tolerance; Humans; Ketamine; Morphine Dependence; Naltrexone; Narcotic Ant

2011
Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm.
    Cell research, 2003, Volume: 13, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Conditioning, Psychological; Cyclic AMP Response Element-Bind

2003
Decrease of tolerance to, and physical dependence on morphine by, glutamate receptor antagonists.
    European journal of pharmacology, 1997, Aug-13, Volume: 332, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Ant

1997
Interference with withdrawal signs of naloxone-induced opiate withdrawal under anesthesia is anesthetic-specific in opiate-dependent rats.
    Life sciences, 2001, Dec-21, Volume: 70, Issue:5

    Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Defecation; Dose-Response Relationship, Dru

2001
Effects of MK 801 on morphine physical dependence: attenuation and intensification.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Animals; Dextromethorphan; Dizocilpine Maleate; Ketamine; Male; Morphine; Morphine Dependence; Rats;

1992