Page last updated: 2024-10-29

ketamine and Migraine with Aura

ketamine has been researched along with Migraine with Aura in 3 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Migraine with Aura: A subtype of migraine disorder, characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred VISION; HALLUCINATIONS; VERTIGO; NUMBNESS; and difficulty in concentrating and speaking. Aura is usually followed by features of the COMMON MIGRAINE, such as PHOTOPHOBIA; PHONOPHOBIA; and NAUSEA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Migraine aura is probably caused by cortical-spreading depression."5.31Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine. ( Dichgans, M; Diener, HC; Herzog, J; Kaube, H; Käufer, T, 2000)
"We review the published literature on migraine with prolonged aura (PA), specifically with regards to the phenotype and treatment options."2.58Migraine with prolonged aura: phenotype and treatment. ( Afridi, S; Viana, M, 2018)
"Migraine aura is probably caused by cortical-spreading depression."1.31Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine. ( Dichgans, M; Diener, HC; Herzog, J; Kaube, H; Käufer, T, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Viana, M1
Afridi, S1
Afridi, SK1
Giffin, NJ1
Kaube, H2
Goadsby, PJ1
Herzog, J1
Käufer, T1
Dichgans, M1
Diener, HC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketamine for Refractory Chronic Migraine: a Pilot Study[NCT03896256]Early Phase 16 participants (Actual)Interventional2019-03-22Completed
Intranasal Ketamine Versus Intranasal Midazolam Plus Fentanyl in Treating Pain Associated With Incision and Drainage of Abscesses in the Pediatric Emergency Department: A Randomized Controlled Trial[NCT02635282]Phase 419 participants (Actual)Interventional2016-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ketamine and Migraine with Aura

ArticleYear
Migraine with prolonged aura: phenotype and treatment.
    Naunyn-Schmiedeberg's archives of pharmacology, 2018, Volume: 391, Issue:1

    Topics: Humans; Ketamine; Lamotrigine; Migraine with Aura; Phenotype; Pilot Projects; Randomized Controlled

2018

Trials

1 trial available for ketamine and Migraine with Aura

ArticleYear
A randomized controlled trial of intranasal ketamine in migraine with prolonged aura.
    Neurology, 2013, Feb-12, Volume: 80, Issue:7

    Topics: Administration, Intranasal; Adult; Analgesics; Double-Blind Method; Female; Humans; Inpatients; Keta

2013
A randomized controlled trial of intranasal ketamine in migraine with prolonged aura.
    Neurology, 2013, Feb-12, Volume: 80, Issue:7

    Topics: Administration, Intranasal; Adult; Analgesics; Double-Blind Method; Female; Humans; Inpatients; Keta

2013
A randomized controlled trial of intranasal ketamine in migraine with prolonged aura.
    Neurology, 2013, Feb-12, Volume: 80, Issue:7

    Topics: Administration, Intranasal; Adult; Analgesics; Double-Blind Method; Female; Humans; Inpatients; Keta

2013
A randomized controlled trial of intranasal ketamine in migraine with prolonged aura.
    Neurology, 2013, Feb-12, Volume: 80, Issue:7

    Topics: Administration, Intranasal; Adult; Analgesics; Double-Blind Method; Female; Humans; Inpatients; Keta

2013

Other Studies

1 other study available for ketamine and Migraine with Aura

ArticleYear
Aura in some patients with familial hemiplegic migraine can be stopped by intranasal ketamine.
    Neurology, 2000, Jul-12, Volume: 55, Issue:1

    Topics: Administration, Intranasal; Adult; Calcium Channels, P-Type; Calcium Channels, Q-Type; Epilepsy; Exc

2000