ketamine has been researched along with MS (Multiple Sclerosis) in 4 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proposed study is a single-center, phase II, randomized, double-blind, parallel-group, active-placebo-controlled trial of intravenous low-dose ketamine in patients with MS fatigue." | 9.69 | Low-dose ketamine infusion for the treatment of multiple sclerosis fatigue (INKLING-MS): Study protocol for a randomized, double-blind, active placebo-controlled phase II trial. ( Ghajarzadeh, M; Nourbakhsh, B; Roman, S; Vega, L, 2023) |
| "To determine the tolerability, safety, and efficacy of low-dose ketamine infusion for MS-related fatigue." | 9.41 | Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigue. ( Balshi, A; Fitzgerald, KC; Kaplin, A; Maher, D; Morris, B; Nourbakhsh, B; Soroosh, A, 2021) |
| "The proposed study is a single-center, phase II, randomized, double-blind, parallel-group, active-placebo-controlled trial of intravenous low-dose ketamine in patients with MS fatigue." | 5.69 | Low-dose ketamine infusion for the treatment of multiple sclerosis fatigue (INKLING-MS): Study protocol for a randomized, double-blind, active placebo-controlled phase II trial. ( Ghajarzadeh, M; Nourbakhsh, B; Roman, S; Vega, L, 2023) |
| "To determine the tolerability, safety, and efficacy of low-dose ketamine infusion for MS-related fatigue." | 5.41 | Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigue. ( Balshi, A; Fitzgerald, KC; Kaplin, A; Maher, D; Morris, B; Nourbakhsh, B; Soroosh, A, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Chang, L | 1 |
| Tan, Y | 1 |
| Qu, Y | 1 |
| Shan, J | 1 |
| Hashimoto, K | 1 |
| Ghajarzadeh, M | 1 |
| Roman, S | 1 |
| Vega, L | 1 |
| Nourbakhsh, B | 2 |
| Fitzgerald, KC | 1 |
| Morris, B | 1 |
| Soroosh, A | 1 |
| Balshi, A | 1 |
| Maher, D | 1 |
| Kaplin, A | 1 |
| Losada de Azpiazu, FJ | 1 |
| Sánchez Del Mazo, T | 1 |
| Rodríguez Alvarez, E | 1 |
| Villar Mirabal, I | 1 |
| Fraga García, M | 1 |
| Pose Cambeiro, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A PILOT STUDY OF INTRAVENOUS, SUBANESTHETIC DOSE OF KETAMINE VS PLACEBO, A CROSSOVER DESIGN, FOR MULTIPLE SCLEROSIS RELATED FATIGUE[NCT06064162] | Early Phase 1 | 20 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ketamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Low-dose ketamine infusion for the treatment of multiple sclerosis fatigue (INKLING-MS): Study protocol for a randomized, double-blind, active placebo-controlled phase II trial.
Topics: Adult; Clinical Trials, Phase II as Topic; Double-Blind Method; Fatigue; Humans; Ketamine; Midazolam | 2023 |
Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis-related fatigue.
Topics: Double-Blind Method; Fatigue; Humans; Ketamine; Multiple Sclerosis; Pilot Projects; Treatment Outcom | 2021 |
2 other studies available for ketamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
(R)-ketamine ameliorates the progression of experimental autoimmune encephalomyelitis in mice.
Topics: Animals; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Humans; Ketamine; Mice | 2021 |
[Anesthesia in multiple sclerosis patients: a proso of a clinical case].
Topics: Adult; Anesthesia; Diazepam; Epinephrine; Humans; Ketamine; Male; Multiple Sclerosis; Urinary Bladde | 1982 |