Page last updated: 2024-10-29

ketamine and Liver Dysfunction

ketamine has been researched along with Liver Dysfunction in 10 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Ketamine has hepatoprotective effects, while isoflurane does not."5.33Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2. ( Gonzalez, EA; Helmer, KS; Mercer, DW; Robinson, EK; Suliburk, JW, 2005)
"The ketamine-treated rats were injected with 100 mg/kg of ketamine intramuscularly 30 min before LPS (0."5.29Ketamine suppresses tumor necrosis factor-alpha activity and mortality in carrageenan-sensitized endotoxin shock model. ( Koga, K; Matsumoto, T; Ogata, M; Shigematsu, A; Takenaka, I, 1994)
"Ketamine has been shown to prevent these effects."1.35Ketamine-induced hepatoprotection: the role of heme oxygenase-1. ( Adams, SD; Helmer, KS; Mercer, DW; Suliburk, JW; Ward, JL; Zuckerbraun, BS, 2009)
"Ketamine has hepatoprotective effects, while isoflurane does not."1.33Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2. ( Gonzalez, EA; Helmer, KS; Mercer, DW; Robinson, EK; Suliburk, JW, 2005)
"The ketamine-treated rats were injected with 100 mg/kg of ketamine intramuscularly 30 min before LPS (0."1.29Ketamine suppresses tumor necrosis factor-alpha activity and mortality in carrageenan-sensitized endotoxin shock model. ( Koga, K; Matsumoto, T; Ogata, M; Shigematsu, A; Takenaka, I, 1994)
"Ketamine is a safe anesthetic to use for open liver biopsy in patients with underlying liver disease, although poor muscle relaxation and nightmares may be significant side effects."1.27Ketamine hydrochloride as sole anesthetic for open liver biopsy. ( Abu Khalaf, A; Abu Khalaf, M; Amr, S; Takrouri, M; Toukan, A, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suliburk, JW2
Ward, JL1
Helmer, KS2
Adams, SD1
Zuckerbraun, BS1
Mercer, DW2
Mason, KP1
Padua, H1
Fontaine, PJ1
Zurakowski, D1
Sornsakrin, M1
Helmke, K1
Briem-Richter, A1
Ganschow, R1
Ismaĭlov, IS1
Mamedov, II1
Rashidova, MA1
Gonzalez, EA1
Robinson, EK1
Kamiyama, Y1
Kashiwagi, S1
Satoyoshi, M1
Koga, K1
Ogata, M1
Takenaka, I1
Matsumoto, T1
Shigematsu, A1
Schaps, D1
Hauenschild, E1
Abu Khalaf, A1
Takrouri, M1
Toukan, A1
Abu Khalaf, M1
Amr, S1
Briciu, RM1
Filipescu, Z1

Other Studies

10 other studies available for ketamine and Liver Dysfunction

ArticleYear
Ketamine-induced hepatoprotection: the role of heme oxygenase-1.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:6

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Chemical an

2009
Radiologist-supervised ketamine sedation for solid organ biopsies in children and adolescents.
    AJR. American journal of roentgenology, 2009, Volume: 192, Issue:5

    Topics: Adolescent; Anesthetics, Dissociative; Biopsy; Child; Child, Preschool; Confidence Intervals; Female

2009
Value of ultrasound-guided percutaneous liver biopsy in children following liver transplantation.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 51, Issue:5

    Topics: Adolescent; Biopsy, Needle; Child; Child, Preschool; Female; Humans; Incidence; Infant; Ketamine; Li

2010
[Evaluation of efficacy and safety of optimized based on the ketamine modified neuroleptanalgesia during operations on the biliary tract and liver].
    Khirurgiia, 2010, Issue:10

    Topics: Aged; Analgesics; Anesthesia, General; Biliary Tract Diseases; Female; Humans; Ketamine; Liver Disea

2010
Ketamine attenuates liver injury attributed to endotoxemia: role of cyclooxygenase-2.
    Surgery, 2005, Volume: 138, Issue:2

    Topics: Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhi

2005
[Caudal anesthesia for upper abdominal surgery in poor risk infants and children. I. Comparative studies with "Liverpool technique" (author's transl)].
    Masui. The Japanese journal of anesthesiology, 1980, Volume: 29, Issue:2

    Topics: Abdomen; Anesthesia, Caudal; Anesthesia, Epidural; Bupivacaine; Child; Child, Preschool; Humans; Inf

1980
Ketamine suppresses tumor necrosis factor-alpha activity and mortality in carrageenan-sensitized endotoxin shock model.
    Circulatory shock, 1994, Volume: 44, Issue:3

    Topics: Acidosis; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Carrageenan; Endotoxins; Hydrogen-

1994
[The use of ketamine in patients with liver damage (author's transl)].
    Der Anaesthesist, 1977, Volume: 26, Issue:4

    Topics: Anesthesia; Blood Pressure; Droperidol; Fatty Liver; Heart Rate; Hepatitis; Humans; Jaundice; Ketami

1977
Ketamine hydrochloride as sole anesthetic for open liver biopsy.
    Middle East journal of anaesthesiology, 1988, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Biopsy; Child; Female; Humans; Ketamine; Liver; Liver Di

1988
[Dissociated anesthesia].
    Chirurgia, 1974, Volume: 23, Issue:6

    Topics: Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Female; Gastrointestinal Diseases; Huma

1974