ketamine has been researched along with Learning Disabilities in 8 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3 mg/kg ketamine and then underwent ECT under propofol anesthesia, and a control group, which received isovolumetric placebo (normal saline) and then underwent ECT under propofol anesthesia." | 5.24 | Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study. ( Chen, J; Chen, Q; Hao, X; Li, X; Luo, Q; Meng, H; Min, S; Peng, L, 2017) |
| "While the effects of varenicline across the different behavioral tasks were modest, these data suggest that varenicline may have potential as a repurposed drug for disorders of cognition associated with aging (e." | 3.83 | Effects of the nicotinic agonist varenicline on the performance of tasks of cognition in aged and middle-aged rhesus and pigtail monkeys. ( Callahan, PM; Plagenhoef, M; Terry, AV, 2016) |
| "Demyelination was assessed by luxol fast blue staining, and immunohistological staining of myelin-binding protein (MBP)." | 1.39 | Kindling-induced learning deficiency and possible cellular and molecular involved mechanisms. ( Ahmad-Molaei, L; Ghasemi, R; Hosseini, A; Motamedi, F; Naderi, N; Nejadhoseynian, M; Ronaghi, A; Sherafat, MA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanku, RKK | 1 |
| John, JS | 1 |
| Salkovitz, M | 1 |
| Ilies, MA | 1 |
| Walker, EA | 1 |
| Huang, S | 1 |
| Dai, Y | 1 |
| Zhang, Z | 1 |
| Hao, W | 1 |
| Chen, H | 1 |
| Terry, AV | 1 |
| Plagenhoef, M | 1 |
| Callahan, PM | 1 |
| Niquet, J | 1 |
| Baldwin, R | 1 |
| Norman, K | 1 |
| Suchomelova, L | 1 |
| Lumley, L | 1 |
| Wasterlain, CG | 1 |
| Chen, Q | 1 |
| Min, S | 1 |
| Hao, X | 1 |
| Peng, L | 1 |
| Meng, H | 1 |
| Luo, Q | 1 |
| Chen, J | 1 |
| Li, X | 1 |
| Bolton, MM | 1 |
| Heaney, CF | 1 |
| Sabbagh, JJ | 1 |
| Murtishaw, AS | 1 |
| Magcalas, CM | 1 |
| Kinney, JW | 1 |
| Sherafat, MA | 1 |
| Ronaghi, A | 1 |
| Ahmad-Molaei, L | 1 |
| Nejadhoseynian, M | 1 |
| Ghasemi, R | 1 |
| Hosseini, A | 1 |
| Naderi, N | 1 |
| Motamedi, F | 1 |
| Huang, L | 1 |
| Liu, Y | 1 |
| Jin, W | 1 |
| Ji, X | 1 |
| Dong, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Combined Ketamine and Midazolam for Treatment of Generalized Convulsive Status Epilepticus in Children .[NCT05779657] | Phase 2/Phase 3 | 144 participants (Anticipated) | Interventional | 2023-03-21 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ketamine and Learning Disabilities
| Article | Year |
|---|---|
Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study.
Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Intravenous; Asian People; Depressive Disorder, Ma | 2017 |
7 other studies available for ketamine and Learning Disabilities
| Article | Year |
|---|---|
Potential learning and memory disruptors and enhancers in a simple, 1-day operant task in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adjuvants, Anesthesia; Animals; Conditioning, Operant; Disea | 2018 |
Docosahexaenoic acid intake ameliorates ketamine-induced impairment of spatial cognition and learning ability in ICR mice.
Topics: Animals; Cognition; Cognition Disorders; Docosahexaenoic Acids; gamma-Aminobutyric Acid; Hippocampus | 2014 |
Effects of the nicotinic agonist varenicline on the performance of tasks of cognition in aged and middle-aged rhesus and pigtail monkeys.
Topics: Aging; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition; Drug Repositioning; Excitatory A | 2016 |
Midazolam-ketamine dual therapy stops cholinergic status epilepticus and reduces Morris water maze deficits.
Topics: Animals; Anticonvulsants; Brain; Cholinergic Agents; Disease Models, Animal; Drug Synergism; Drug Th | 2016 |
Deficits in emotional learning and memory in an animal model of schizophrenia.
Topics: Analysis of Variance; Animals; Brain; Conditioning, Classical; Disease Models, Animal; Excitatory Am | 2012 |
Kindling-induced learning deficiency and possible cellular and molecular involved mechanisms.
Topics: Animals; Apoptosis; Avoidance Learning; Demyelinating Diseases; Disease Models, Animal; Electron Tra | 2013 |
Ketamine potentiates hippocampal neurodegeneration and persistent learning and memory impairment through the PKCĪ³-ERK signaling pathway in the developing brain.
Topics: Analgesics; Analysis of Variance; Animals; Animals, Newborn; Brain; Disease Models, Animal; Enzyme I | 2012 |