ketamine has been researched along with Laryngismus in 28 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Laryngismus: A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coughing and laryngospasm are undesirable consequences occurring when patients awaken from general anaesthesia." | 7.11 | Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial. ( Chungsamarnyart, Y; Munjupong, S; Pairart, J, 2022) |
| "4%: airway malalignment (n = 7), laryngospasm (n = 4), apnea (n = 2), and respiratory depression (n = 1)." | 3.70 | Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases. ( Garrett, W; Green, SM; Harris, T; Hestdalen, R; Ho, M; Hopkins, GA; Lynch, EL; Rothrock, SG; Westcott, K, 1998) |
| "Coughing and laryngospasm are undesirable consequences occurring when patients awaken from general anaesthesia." | 3.11 | Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial. ( Chungsamarnyart, Y; Munjupong, S; Pairart, J, 2022) |
| "Laryngospasm was observed in 6 patients without statistical difference between the 2 groups." | 2.77 | Ketamine with and without midazolam for gastrointestinal endoscopies in children. ( Brecelj, J; Orel, R; Trop, TK, 2012) |
| "Such laryngospasm seems to be idiosyncratic, and accordingly, clinicians administering ketamine must be prepared for its rapid identification and management." | 2.46 | Laryngospasm during emergency department ketamine sedation: a case-control study. ( Green, SM; Krauss, B; Roback, MG, 2010) |
| "The primary outcome was laryngospasm." | 1.72 | Predictors of Laryngospasm During 276,832 Episodes of Pediatric Procedural Sedation. ( Cosgrove, P; Cravero, JP; Fleegler, EW; Krauss, BS, 2022) |
| "We report a case of severe laryngospasm following rapid sequence induction in an adult requiring an emergency neurosurgical procedure." | 1.62 | Refractory Severe Laryngospam During Rapid Sequence Induction: A Case Report. ( Maqueda, B; Rousseau, L, 2021) |
| "Upper gastrointestinal endoscopies (UGEs) performed under ketamine sedation may increase the risk of respiratory adverse events (RAEs) due to pharyngeal stimulation." | 1.51 | Topical Pharyngeal Lidocaine Reduces Respiratory Adverse Events During Upper Gastrointestinal Endoscopies Under Ketamine Sedation in Children. ( Estalella-Mendoza, A; Flores-González, JC; Lechuga-Sancho, AM; Rodríguez-Campoy, P; Saldaña-Valderas, M, 2019) |
| "Three patients experienced cardiac arrest without death, all associated with laryngospasm." | 1.43 | Procedural Sedation Outside of the Operating Room Using Ketamine in 22,645 Children: A Report From the Pediatric Sedation Research Consortium. ( Chumpitazi, CE; Grunwell, JR; Kamat, PP; McCracken, CE; Roback, MG; Scherrer, PD; Stockwell, JA; Stormorken, AG; Travers, C, 2016) |
| "Compare the frequency of respiratory adverse events between patients who received intramuscular (IM) versus intravenous ketamine." | 1.35 | Serious adverse events during procedural sedation with ketamine. ( Bachur, R; Melendez, E, 2009) |
| " We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events." | 1.32 | Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003) |
| "Adverse effects included transient laryngospasm (8." | 1.31 | Ketamine sedation for pediatric gastroenterology procedures. ( Green, SM; Harris, T; Klooster, M; Lynch, EL; Rothrock, SG, 2001) |
| "In no case was laryngospasm or total airway obstruction observed." | 1.31 | Additional clinical observations utilizing bispectral analysis. ( Sandler, NA, 2000) |
| "Adverse effects included transient laryngospasm (n = 9), transient partial airway obstruction (n = 5), apnea with bradycardia (n = 1), emesis during the procedure (n = 2), emesis during recovery (n = 9), mild recovery agitation (n = 10), moderate-to-severe recovery agitation (n = 1), and excessive salivation (n = 4)." | 1.31 | Ketamine sedation for pediatric critical care procedures. ( Abd Allah, S; Cline, J; Denmark, TK; Green, SM; Roghair, C; Rothrock, SG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (25.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Cosgrove, P | 1 |
| Krauss, BS | 1 |
| Cravero, JP | 1 |
| Fleegler, EW | 1 |
| Chungsamarnyart, Y | 1 |
| Pairart, J | 1 |
| Munjupong, S | 1 |
| Maqueda, B | 1 |
| Rousseau, L | 1 |
| Flores-González, JC | 1 |
| Estalella-Mendoza, A | 1 |
| Rodríguez-Campoy, P | 1 |
| Saldaña-Valderas, M | 1 |
| Lechuga-Sancho, AM | 1 |
| Jalili, S | 1 |
| Esmaeeili, A | 1 |
| Kamali, K | 1 |
| Rashtchi, V | 1 |
| Grunwell, JR | 1 |
| Travers, C | 1 |
| McCracken, CE | 1 |
| Scherrer, PD | 1 |
| Stormorken, AG | 1 |
| Chumpitazi, CE | 1 |
| Roback, MG | 2 |
| Stockwell, JA | 1 |
| Kamat, PP | 1 |
| Xue, FS | 1 |
| Liao, X | 1 |
| Xu, YC | 1 |
| Yang, QY | 1 |
| Melendez, E | 1 |
| Bachur, R | 1 |
| Green, SM | 5 |
| Krauss, B | 3 |
| Brecelj, J | 1 |
| Trop, TK | 1 |
| Orel, R | 1 |
| Erdogan Kayhan, G | 1 |
| Yucel, A | 1 |
| Colak, YZ | 1 |
| Ozgul, U | 1 |
| Yologlu, S | 1 |
| Karlıdag, R | 1 |
| Ersoy, MO | 1 |
| Betemariam, K | 1 |
| Agrawal, D | 1 |
| Manzi, SF | 1 |
| Gupta, R | 1 |
| Cohen, VG | 1 |
| Liu, CM | 1 |
| Huang, CH | 1 |
| Lau, HP | 1 |
| Yeh, HM | 1 |
| Lassiter, HA | 1 |
| Rothrock, SG | 4 |
| Lynch, EL | 2 |
| Ho, M | 1 |
| Harris, T | 2 |
| Hestdalen, R | 1 |
| Hopkins, GA | 1 |
| Garrett, W | 1 |
| Westcott, K | 1 |
| Klooster, M | 1 |
| Sandler, NA | 1 |
| Denmark, TK | 1 |
| Cline, J | 1 |
| Roghair, C | 1 |
| Abd Allah, S | 1 |
| Lanning, CF | 1 |
| Harmel, MH | 1 |
| Nakamura, R | 1 |
| Johnson, NE | 2 |
| Karayan, J | 1 |
| Lacoste, L | 1 |
| Breuil, K | 1 |
| Abaliev, MS | 1 |
| Jensen, AH | 1 |
| Dalsgård, M | 1 |
| Thorshauge, C | 1 |
| Chüden, HG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inonu University Faculty of Medicine Department of Anesthesiology and Reanimation[NCT02819375] | Phase 4 | 45 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638] | 240 participants (Anticipated) | Interventional | 2015-10-31 | Not yet recruiting | |||
| Music in Urgent and Emergent Settings (MUES) Trial: Phase Two[NCT02363179] | 1,107 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ketamine and Laryngismus
| Article | Year |
|---|---|
Laryngospasm during emergency department ketamine sedation: a case-control study.
Topics: Anesthetics, Dissociative; Case-Control Studies; Chi-Square Distribution; Emergency Service, Hospita | 2010 |
Ketamine anesthesia.
Topics: Anesthesia, General; Animals; Blood Pressure; Bronchial Spasm; Central Nervous System; Central Venou | 1975 |
4 trials available for ketamine and Laryngismus
| Article | Year |
|---|---|
Comparison of the effects of intravenous propofol and propofol with low-dose ketamine on preventing postextubation cough and laryngospasm among patients awakening from general anaesthesia: A prospective randomised clinical trial.
Topics: Anesthesia, General; Anesthetics, Intravenous; Cough; Humans; Ketamine; Laryngismus; Propofol; Prosp | 2022 |
Comparison of effects of propofol and ketofol (Ketamine-Propofol mixture) on emergence agitation in children undergoing tonsillectomy.
Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Bronchial Spasm; Child; Child, Pres | 2019 |
Ketamine with and without midazolam for gastrointestinal endoscopies in children.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Drug Administrat | 2012 |
Ketofol (mixture of ketamine and propofol) administration in electroconvulsive therapy.
Topics: Adult; Anesthesia; Anesthetics, Dissociative; Anesthetics, Intravenous; Blood Pressure; Double-Blind | 2012 |
22 other studies available for ketamine and Laryngismus
| Article | Year |
|---|---|
Predictors of Laryngospasm During 276,832 Episodes of Pediatric Procedural Sedation.
Topics: Anesthesia; Child; Humans; Ketamine; Laryngismus; Prevalence; Propofol | 2022 |
Refractory Severe Laryngospam During Rapid Sequence Induction: A Case Report.
Topics: Adult; Humans; Ketamine; Laryngismus; Rapid Sequence Induction and Intubation; Succinylcholine | 2021 |
Topical Pharyngeal Lidocaine Reduces Respiratory Adverse Events During Upper Gastrointestinal Endoscopies Under Ketamine Sedation in Children.
Topics: Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Local; Child; Child, Preschool; Conscious | 2019 |
Procedural Sedation Outside of the Operating Room Using Ketamine in 22,645 Children: A Report From the Pediatric Sedation Research Consortium.
Topics: Adolescent; Child; Child, Preschool; Emergency Service, Hospital; Female; Heart Arrest; Hospitals, G | 2016 |
Sedation and anesthesia for fiberoptic intubation in management of pediatric difficult airways.
Topics: Adolescent; Anesthesia, Inhalation; Anesthetics, Dissociative; Anesthetics, Inhalation; Apnea; Child | 2008 |
Serious adverse events during procedural sedation with ketamine.
Topics: Boston; Case-Control Studies; Child; Child, Preschool; Deep Sedation; Emergency Service, Hospital; F | 2009 |
Experience in the use of laryngeal mask airway in Tikur Anbessa Hospital.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Dissociative; An | 2002 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C | 2003 |
Recurrent episodes of intractable laryngospasm during dissociative sedation with intramuscular ketamine.
Topics: Anesthetics, Dissociative; Child, Preschool; Facial Injuries; Female; Humans; Injections, Intramuscu | 2006 |
Anesthetic management for two infants undergoing surgery for tension pneumatoceles.
Topics: Analgesics; Anesthesia; Blood Pressure; Cysts; Heart Rate; Humans; Infant; Infant, Newborn; Intubati | 2007 |
Epiglottitis: laryngospasm at intubation.
Topics: Child, Preschool; Epiglottis; Humans; Intubation, Intratracheal; Ketamine; Laryngismus; Laryngitis; | 1982 |
Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases.
Topics: Adolescent; Affective Symptoms; Anesthetics, Dissociative; Apnea; Child; Child, Preschool; Conscious | 1998 |
Ketamine sedation for pediatric gastroenterology procedures.
Topics: Adolescent; Adult; Age Factors; Anesthetics, Dissociative; Child; Child, Preschool; Gastroenterology | 2001 |
Additional clinical observations utilizing bispectral analysis.
Topics: Airway Obstruction; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthe | 2000 |
Ketamine sedation for pediatric critical care procedures.
Topics: Adolescent; Adult; Anesthesia; Anesthetics, Dissociative; Child; Child, Preschool; Critical Care; Fe | 2001 |
Ketamine sedation for pediatric procedures: Part 1, A prospective series.
Topics: Adolescent; Anxiety; Child; Child, Preschool; Drug Evaluation; Emergency Medicine; Female; Humans; H | 1990 |
[Allergy to ketamine].
Topics: Adult; Drug Hypersensitivity; Erythema; Female; Humans; Ketamine; Laryngismus; Skin Tests | 1990 |
Pain management in the pediatric emergency department.
Topics: Child; Emergency Service, Hospital; Humans; Injections, Intramuscular; Ketamine; Laryngismus; Pain | 1989 |
[Total laryngospasm in kalipsol anesthesia].
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anesthetics; Cesarean Section; Female; Huma | 1985 |
[200+200 anaesthesias with Ketalar--a comparison].
Topics: Adolescent; Anesthetics; Blood Pressure; Child; Child, Preschool; Cyclohexanes; Diazepam; Hallucinat | 1971 |
[Experience with Ketalar anesthesia].
Topics: Anesthetics; Blood Pressure; Child; Cyclohexanes; Cyclopropanes; Female; Halothane; Humans; Hyperten | 1971 |
[Clinical experiences with ketamine in adeno-tonsillectmies].
Topics: Adenoids; Adolescent; Adult; Aged; Analgesics; Anesthesia, Intravenous; Child; Child, Preschool; Cyc | 1971 |