Page last updated: 2024-10-29

ketamine and Intellectual Disability

ketamine has been researched along with Intellectual Disability in 13 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"Watson's syndrome is an uncommon genetic disorder whose features include mental retardation and pulmonary valvular stenosis."1.29Anaesthesia for caesarean section in a patient with Watson's syndrome. ( Conway, JB; Posner, M, 1994)
"Indications for this were mental retardation and dental fear."1.28General anaesthesia of out-patients in pedodontics. ( Dénes, J; Mikecz, G; Tarján, I, 1990)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's6 (46.15)18.2507
2000's0 (0.00)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horacek, J1
Palenicek, T1
Malek, J1
Scigel, V1
Kurzova, A1
Hess, L1
Malaquin, JM1
Reroń, E1
Popielski, L1
Conway, JB1
Posner, M1
Rashiq, S1
Guenther, C1
Naunton, RF1
Zerlin, S1
Kaplan, S1
Hirschowitz, AS1
Brown, D1
Rosen, D1
Elkins, TE1
Petros, AJ1
Hausler, R1
Cao, M1
Magnin, C1
Mulette, P1
Tarján, I2
Mikecz, G2
Dénes, J2
Lyons, GD1
Berlin, CI1
Lousteau, RJ1
Ellis, MS1
Yarbrough, WM1

Trials

2 trials available for ketamine and Intellectual Disability

ArticleYear
The influence of clonidine on oral ketamine-midazolam premedication in intellectually disabled patients indicated for dental procedures: double-blind comparison of two sedation regimes.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:4

    Topics: Adult; Anesthesia, Dental; Clinical Protocols; Clonidine; Dental Care for Disabled; Disabled Persons

2012
[Clinical experiences with Ketalar used for evoked response audiometry in children (author's transl)].
    Otolaryngologia polska = The Polish otolaryngology, 1981, Volume: 35, Issue:4-6

    Topics: Aphasia, Broca; Audiometry; Audiometry, Evoked Response; Child; Child, Preschool; Clinical Trials as

1981

Other Studies

11 other studies available for ketamine and Intellectual Disability

ArticleYear
[Ketamine via rectal route for the induction of pediatric anesthesia].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:5

    Topics: Adolescent; Anesthesia, Intravenous; Anesthesia, Rectal; Cardiac Catheterization; Child; Child, Pres

1984
Anaesthesia for caesarean section in a patient with Watson's syndrome.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:11

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; B

1994
Dental restoration using oral ketamine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:9

    Topics: Administration, Oral; Adult; Anesthesia, Dental; Anesthesia, General; Anesthesia, Inhalation; Anesth

1993
The evaluation of peripheral auditory function in infants and children.
    Otolaryngologic clinics of North America, 1977, Volume: 10, Issue:1

    Topics: Action Potentials; Anesthesia, General; Anesthesia, Intravenous; Child, Preschool; Cochlea; Deafness

1977
The dental treatment of problem children under ketamine analgesia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Mar-01, Volume: 49, Issue:9

    Topics: Adolescent; Analgesia; Anesthesia, Dental; Anxiety; Child; Child, Preschool; Hemophilia A; Humans; I

1975
Sedating women with mental retardation for routine gynecologic examination: an ethical analysis.
    The Journal of clinical ethics, 1992,Spring, Volume: 3, Issue:1

    Topics: Adult; Anesthesia, Conduction; Beneficence; Dehumanization; Ethical Analysis; Ethics, Medical; Femal

1992
Oral ketamine. Its use for mentally retarded adults requiring day care dental treatment.
    Anaesthesia, 1991, Volume: 46, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anesthesia Recovery Period; Anesthesia, De

1991
Low frequency hearing threshold determination in newborns, infants and mentally retarded children by middle latency responses.
    Acta oto-laryngologica. Supplementum, 1991, Volume: 482

    Topics: Acoustic Stimulation; Audiometry, Evoked Response; Audiometry, Pure-Tone; Auditory Threshold; Brain

1991
General anaesthesia of out-patients in pedodontics.
    Journal of the International Association of Dentistry for Children, 1990, Volume: 20, Issue:2

    Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Atropine; Child

1990
[Ambulatory anesthesia in pediatric dentistry].
    Fogorvosi szemle, 1989, Volume: 82, Issue:2

    Topics: Ambulatory Care; Anesthesia, Dental; Anesthesia, General; Atropine; Child; Child, Preschool; Dental

1989
Electrocochleography with retardates.
    The Laryngoscope, 1974, Volume: 84, Issue:6

    Topics: Acoustic Stimulation; Action Potentials; Adult; Anesthesia; Audiometry; Child; Cochlea; Electrodes,

1974