ketamine has been researched along with Innate Inflammatory Response in 93 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study applies free-water imaging to investigate the relationship between altered peripheral inflammation and WM microstructure and their predictive value in determining response to ketamine treatment in MDD." | 9.51 | Association between peripheral inflammation and free-water imaging in Major Depressive Disorder before and after ketamine treatment - A pilot study. ( Cetin-Karayumak, S; Chunga, N; Espinoza, RT; Kubicki, A; Kubicki, M; Langhein, M; Lyall, AE; Mulert, C; Narr, KL; Pasternak, O; Seitz-Holland, J, 2022) |
| "Despite a burgeoning body of literature demonstrating that inflammation is linked to TRD, there is still a lack of comprehensive research on the relationship between proinflammatory biomarkers and ketamine's antidepressant effect on TRD patients." | 9.22 | Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review. ( Gu, J; Sukhram, SD; Yilmaz, G, 2022) |
| "These findings suggest that the routine use of a single dose of ketamine prior to chest wall incision is not effective at reducing pain or inflammation in thoracic surgery patients at 24 h postoperatively." | 9.15 | A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery. ( Bennett-Guerrero, E; D'Alonzo, RC; D'Amico, TA; Harpole, DH; Podgoreanu, M; Shaw, AD, 2011) |
| "Ketamine infiltration had brief local analgesic effects, but several measures of pain and hyperalgesia were unaffected." | 9.08 | Peripheral analgesic effects of ketamine in acute inflammatory pain. ( Galle, TS; Kehlet, H; Pedersen, JL, 1998) |
| "This review discusses the place of the old anesthetic ketamine in pediatric anesthesia." | 8.84 | Something new about ketamine for pediatric anesthesia? ( De Kock, M; Lois, F, 2008) |
| " Recently, we reported that the nuclear factor of activated T cells 4 (NFATc4) signaling might contribute to sustained prophylactic effects of new antidepressant (R)-ketamine in lipopolysaccharide (LPS)-treated inflammation model of depression." | 8.12 | A role of microRNA-149 in the prefrontal cortex for prophylactic actions of (R)-ketamine in inflammation model. ( Chang, L; Fujita, Y; Hashimoto, K; Ma, L; Qu, Y; Shan, J; Wang, L; Wang, X, 2022) |
| "The study concluded that ketamine reduced oxidative stress and attenuated asthmatic symptoms (neutrophilic airway inflammation) by activating the Nrf2-Keap1 pathway, with 75 mg/kg ketamine showing the best results." | 8.12 | Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model. ( Wang, Q; Xiao, S; Yang, D; Zhou, Y, 2022) |
| "The present study evaluated the effects of systemically administered ketamine treatment in a lipopolysaccharide (LPS)-induced mouse model of depression." | 7.91 | Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression. ( Hua, D; Hua, F; Huang, N; Jiang, R; Li, S; Luo, A; Wang, Y; Wu, Y; Yang, C; Yang, L; Yu, F; Zhan, G; Zhu, B, 2019) |
| "Ketamine-induced ulcerative cystitis (KIC) initially damaged the bladder mucosa and induced contracted bladder thereafter." | 7.85 | Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model. ( Chuang, SM; Ho, WT; Juan, YS; Lee, YC; Lee, YL; Lin, KL; Lu, MC; Wu, BN; Wu, WJ; Yuan, SF, 2017) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 7.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| "To explore the effects of ketamine on hemo-dynamics, plasma proinflammatory cytokine (TNF-alpha and IL-6) levels and nuclear factor kappa B (NF-kappaB) activation during polymicrobial sepsis." | 7.73 | Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats. ( Du, ZH; Jia, BH; Ke, JJ; Li, JG; Song, XM; Wang, YL; Zhou, Q, 2006) |
| "These results demonstrated that ketamine produced antinociceptive effects through an activation of the monoaminergic descending inhibitory system, whereas, in a unilateral peripheral inflammation-induced hyperalgesic state, the monoaminergic system did not contribute to the antihyperalgesic effects of ketamine." | 7.70 | Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation. ( Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Sonoda, H, 2000) |
| "Ketamine is a novel rapid-acting antidepressant with high efficacy in treatment-resistant patients." | 6.72 | Ketamine's effect on inflammation and kynurenine pathway in depression: A systematic review. ( Kopra, E; Mondelli, V; Nikkheslat, N; Pariante, C, 2021) |
| "Depression is a worldwide illness with a significant impact on both family and society." | 6.61 | Crosstalk Between Inflammation and Glutamate System in Depression: Signaling Pathway and Molecular Biomarkers for Ketamine's Antidepressant Effect. ( Cui, W; Hong, W; Li, MD; Liu, Z; Ning, Y; Wang, J, 2019) |
| "Esketamine and ketamine have been shown to decrease inflammation in numerous ways principally through reducing pro-inflammatory cytokines (e." | 5.91 | The Glutamatergic System in Treatment-Resistant Depression and Comparative Effectiveness of Ketamine and Esketamine: Role of Inflammation? ( Cook, J; Halaris, A, 2023) |
| "Moreover, fentany-linduced-hyperalgesia and changes in the expression of the aforementioned proteins can be attenuated by TAK-242, an inhibitor of TLR4, as well as ketamine." | 5.91 | A single dose of ketamine relieves fentanyl-induced-hyperalgesia by reducing inflammation initiated by the TLR4/NF-κB pathway in rat spinal cord neurons. ( Chang, L; Chen, J; Li, Q; Liu, P; Luo, Q; Shu, H; Wang, L; Wu, G; Xiong, Y; Zhou, X, 2023) |
| "Ketamine is an anesthetic drug that is widely used in human and veterinary medicine." | 5.72 | Downregulation of the NLRP3/Caspse-1 Pathway Ameliorates Ketamine-Induced Liver Injury and Inflammation in Developing Rats. ( Chen, X; Gao, L; Li, S; Ma, X; Qiu, D; Shen, M; Zhang, Z, 2022) |
| "Ketamine was reported to attenuate oxidative stress in many cases." | 5.56 | Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells. ( Duan, W; Hou, Y; Liu, Y; Meng, F; Wang, T; Zhu, H, 2020) |
| " The present study applies free-water imaging to investigate the relationship between altered peripheral inflammation and WM microstructure and their predictive value in determining response to ketamine treatment in MDD." | 5.51 | Association between peripheral inflammation and free-water imaging in Major Depressive Disorder before and after ketamine treatment - A pilot study. ( Cetin-Karayumak, S; Chunga, N; Espinoza, RT; Kubicki, A; Kubicki, M; Langhein, M; Lyall, AE; Mulert, C; Narr, KL; Pasternak, O; Seitz-Holland, J, 2022) |
| "Ketamine pretreatment was administered by intraperitoneal injections at doses of 100, 50, 12." | 5.36 | Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-De La Garza, FJ, 2010) |
| "Premature infants experience untreated repetitive pain that may alter their brain development." | 5.34 | Ketamine reduces the cell death following inflammatory pain in newborn rat brain. ( Anand, KJ; Bhutta, AT; Garg, S; Hall, RW; Narsinghani, U; Rovnaghi, CR, 2007) |
| "Despite a burgeoning body of literature demonstrating that inflammation is linked to TRD, there is still a lack of comprehensive research on the relationship between proinflammatory biomarkers and ketamine's antidepressant effect on TRD patients." | 5.22 | Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review. ( Gu, J; Sukhram, SD; Yilmaz, G, 2022) |
| "These findings suggest that the routine use of a single dose of ketamine prior to chest wall incision is not effective at reducing pain or inflammation in thoracic surgery patients at 24 h postoperatively." | 5.15 | A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery. ( Bennett-Guerrero, E; D'Alonzo, RC; D'Amico, TA; Harpole, DH; Podgoreanu, M; Shaw, AD, 2011) |
| "To determine whether ketamine administration affects markers of inflammation in cardiac surgery with cardiopulmonary bypass (CPB) and to investigate differences between 2 low-dose ketamine regimens." | 5.12 | A randomized, double-blind, placebo-controlled study assessing the anti-inflammatory effects of ketamine in cardiac surgical patients. ( Bartoc, C; Bennett-Guerrero, E; Du, E; Frumento, RJ; Jalbout, M; Nishanian, E, 2006) |
| "Ketamine infiltration had brief local analgesic effects, but several measures of pain and hyperalgesia were unaffected." | 5.08 | Peripheral analgesic effects of ketamine in acute inflammatory pain. ( Galle, TS; Kehlet, H; Pedersen, JL, 1998) |
| "Subanesthetic ketamine doses rapidly, albeit transiently decrease suicidal ideation, with effects emerging within an hour and persisting up to a week." | 5.01 | Suicide Has Many Faces, So Does Ketamine: a Narrative Review on Ketamine's Antisuicidal Actions. ( Courtet, P; Lengvenyte, A; Olié, E, 2019) |
| "This review discusses the place of the old anesthetic ketamine in pediatric anesthesia." | 4.84 | Something new about ketamine for pediatric anesthesia? ( De Kock, M; Lois, F, 2008) |
| " Recently, we reported that the nuclear factor of activated T cells 4 (NFATc4) signaling might contribute to sustained prophylactic effects of new antidepressant (R)-ketamine in lipopolysaccharide (LPS)-treated inflammation model of depression." | 4.12 | A role of microRNA-149 in the prefrontal cortex for prophylactic actions of (R)-ketamine in inflammation model. ( Chang, L; Fujita, Y; Hashimoto, K; Ma, L; Qu, Y; Shan, J; Wang, L; Wang, X, 2022) |
| "The study concluded that ketamine reduced oxidative stress and attenuated asthmatic symptoms (neutrophilic airway inflammation) by activating the Nrf2-Keap1 pathway, with 75 mg/kg ketamine showing the best results." | 4.12 | Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model. ( Wang, Q; Xiao, S; Yang, D; Zhou, Y, 2022) |
| "Combined prophylactic and therapeutic use of (R)-ketamine could attenuate systemic inflammation and inflammatory multi-organ injury in mice after CLP-induced lethal sepsis." | 4.02 | (R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture. ( Hashimoto, K; Hashimoto, Y; Ma, L; Qu, Y; Shan, J; Wan, X; Zhang, J, 2021) |
| "To explore the effects of GLP-1 agonist, liraglutide, on ketamine-induced hyper-locomotion and cognitive dysfunction and the associated inflammation and oxidative stress in normoglycemic and diabetic rats." | 4.02 | Reduction in TNF alpha and oxidative stress by liraglutide: Impact on ketamine-induced cognitive dysfunction and hyperlocomotion in rats. ( Magdy, Y; Sedky, AA, 2021) |
| "The present study evaluated the effects of systemically administered ketamine treatment in a lipopolysaccharide (LPS)-induced mouse model of depression." | 3.91 | Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression. ( Hua, D; Hua, F; Huang, N; Jiang, R; Li, S; Luo, A; Wang, Y; Wu, Y; Yang, C; Yang, L; Yu, F; Zhan, G; Zhu, B, 2019) |
| " These behavioral effects are associated with i/ a reversal of anxiety and reduced self-care, ii/ a decrease in parenchymal cytokine production, iii/ a modulation of the microglial reactivity and iv/ a decrease in microglial quinolinic acid production that is correlated with plasmatic peripheral production." | 3.91 | Microglial production of quinolinic acid as a target and a biomarker of the antidepressant effect of ketamine. ( Abdel-Ahad, P; Blatzer, M; Callebert, J; Chrétien, F; Danckaert, A; de Maricourt, P; De Medeiros, GF; Gaillard, R; Jouvion, G; Langeron, O; Launay, JM; Maignan, A; Petit, AC; Sharshar, T; Van Steenwinckel, J; Verdonk, F; Vinckier, F, 2019) |
| "Submucosal bladder inflammation was seen in 67% of the rats fed with 300 mg/kg illicit ketamine." | 3.85 | Oral ketamine induced pathological changes of the urinary tract in a rat model. ( Ali Mohd, M; Hasan, MS; Mohamad Wali, HA; Mun, KS; Ong, TA; Rajandram, R; Razack, AHA; Yap, NY, 2017) |
| "Ketamine-induced ulcerative cystitis (KIC) initially damaged the bladder mucosa and induced contracted bladder thereafter." | 3.85 | Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model. ( Chuang, SM; Ho, WT; Juan, YS; Lee, YC; Lee, YL; Lin, KL; Lu, MC; Wu, BN; Wu, WJ; Yuan, SF, 2017) |
| " Ketamine, an anesthetic agent with sedative and analgesic properties, has been shown to have potent anti-inflammatory effects in a variety of models of systemic inflammation." | 3.83 | Ketamine attenuates high mobility group box-1-induced inflammatory responses in endothelial cells. ( Han, G; Huang, L; Jiang, J; Li, S; Liu, Z; Wang, Z, 2016) |
| " In contrast to ketamine/xylazine, this represents a more physiological, translatable strategy for suppression of cardiomyocyte (18)F-FDG uptake when targeting myocardial inflammation." | 3.81 | Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice. ( Bankstahl, JP; Bengel, FM; Thackeray, JT; Wang, Y; Wollert, KC, 2015) |
| "5h) revealed anesthesia associated IFNγ-expression and lymphocyte activation which were not observed when animals were treated with ketamine/xylazine (p<0." | 3.78 | Inflammatory immune responses in a reproducible mouse brain death model. ( Floerchinger, B; Ge, X; Jurisch, A; Lee, YL; Schmid, C; Timsit, MO; Tullius, SG; Yuan, X, 2012) |
| " We hypothesized that the volatile anesthetic sevoflurane (SEVO) attenuates lung inflammation through activation of lung epithelial GABA(A) receptors." | 3.78 | Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. ( Fortis, S; Haitsma, JJ; Lu, WY; Mazer, CD; Parotto, M; Slutsky, AS; Spieth, PM; Zhang, H; Zhong, N, 2012) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 3.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| "To explore the effects of ketamine on hemo-dynamics, plasma proinflammatory cytokine (TNF-alpha and IL-6) levels and nuclear factor kappa B (NF-kappaB) activation during polymicrobial sepsis." | 3.73 | Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats. ( Du, ZH; Jia, BH; Ke, JJ; Li, JG; Song, XM; Wang, YL; Zhou, Q, 2006) |
| "Ketamine, only at a supra-anesthetic dosage, could inhibit endotoxin-induced pulmonary inflammation in vivo." | 3.73 | Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats. ( Duan, M; Li, W; Lin, N; Sun, J; Wang, Z; Xu, J; Yang, J; Zhou, Z, 2005) |
| "The results support the hypothesis that histaminergic system activation leads to mobilisation of compensatory mechanisms in haemorrhagic hypotension." | 3.72 | Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats. ( Jochem, J, 2004) |
| "These results demonstrated that ketamine produced antinociceptive effects through an activation of the monoaminergic descending inhibitory system, whereas, in a unilateral peripheral inflammation-induced hyperalgesic state, the monoaminergic system did not contribute to the antihyperalgesic effects of ketamine." | 3.70 | Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation. ( Kawamata, M; Kawamata, T; Namiki, A; Omote, K; Sonoda, H, 2000) |
| "05), 24 h dosage of analgesia were significantly less (P < 0." | 2.80 | Preoperative and postoperative analgesic techniques in the treatment of patients undergoing transabdominal hysterectomy: a preliminary randomized trial. ( Chen, JQ; Hu, YM; Miao, JZ; Wen, LY; Wu, Z; Xue, R, 2015) |
| "Ketamine is a novel rapid-acting antidepressant with high efficacy in treatment-resistant patients." | 2.72 | Ketamine's effect on inflammation and kynurenine pathway in depression: A systematic review. ( Kopra, E; Mondelli, V; Nikkheslat, N; Pariante, C, 2021) |
| "Depression is a worldwide illness with a significant impact on both family and society." | 2.61 | Crosstalk Between Inflammation and Glutamate System in Depression: Signaling Pathway and Molecular Biomarkers for Ketamine's Antidepressant Effect. ( Cui, W; Hong, W; Li, MD; Liu, Z; Ning, Y; Wang, J, 2019) |
| " Future studies should further examine the anti-inflammatory effect of ketamine during major surgery, determine whether ketamine treatment alters functional outcomes, elucidate the mechanisms of its anti-inflammatory effect, and suggest an appropriate dosing regimen." | 2.48 | Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis. ( Dale, O; Li, Y; Shavit, Y; Somogyi, AA; Sullivan, T, 2012) |
| "Esketamine and ketamine have been shown to decrease inflammation in numerous ways principally through reducing pro-inflammatory cytokines (e." | 1.91 | The Glutamatergic System in Treatment-Resistant Depression and Comparative Effectiveness of Ketamine and Esketamine: Role of Inflammation? ( Cook, J; Halaris, A, 2023) |
| "Moreover, fentany-linduced-hyperalgesia and changes in the expression of the aforementioned proteins can be attenuated by TAK-242, an inhibitor of TLR4, as well as ketamine." | 1.91 | A single dose of ketamine relieves fentanyl-induced-hyperalgesia by reducing inflammation initiated by the TLR4/NF-κB pathway in rat spinal cord neurons. ( Chang, L; Chen, J; Li, Q; Liu, P; Luo, Q; Shu, H; Wang, L; Wu, G; Xiong, Y; Zhou, X, 2023) |
| "Ketamine is an anesthetic drug that is widely used in human and veterinary medicine." | 1.72 | Downregulation of the NLRP3/Caspse-1 Pathway Ameliorates Ketamine-Induced Liver Injury and Inflammation in Developing Rats. ( Chen, X; Gao, L; Li, S; Ma, X; Qiu, D; Shen, M; Zhang, Z, 2022) |
| "Ketamine was reported to attenuate oxidative stress in many cases." | 1.56 | Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells. ( Duan, W; Hou, Y; Liu, Y; Meng, F; Wang, T; Zhu, H, 2020) |
| "Acute fetal hypoxia is a form of fetal stress that stimulates renal vasoconstriction and ischaemia as a consequence of the physiological redistribution of combined ventricular output." | 1.43 | Ketamine suppresses hypoxia-induced inflammatory responses in the late-gestation ovine fetal kidney cortex. ( Chang, EI; Keller-Wood, M; Rabaglino, MB; Richards, EM; Wood, CE; Zárate, MA, 2016) |
| " Although current antidepressants, such as serotonin-reuptake inhibitors, produce subtle changes that take effect in weeks or months, it has recently been shown that treatment with new agents results in an improvement in mood ratings within hours of dosing patients who are resistant to typical antidepressants." | 1.43 | Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. ( Aghajanian, GK; Duman, RS; Krystal, JH; Sanacora, G, 2016) |
| "The pentobarbital effect was significant within 3 days of surgery and persisted through the remainder of the testing period." | 1.37 | Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation. ( Boegel, K; Gold, MS; Gyulai, FE; Moore, KK, 2011) |
| "In prestressed rats, fULD-induced hyperalgesia and the exaggerated inflammatory hyperalgesia were prevented NMDA receptor antagonists." | 1.37 | Endogenous opioids released during non-nociceptive environmental stress induce latent pain sensitization Via a NMDA-dependent process. ( Chateauraynaud, J; Gavello-Baudy, S; Laboureyras, E; Laulin, JP; Le Roy, C; Simonnet, G, 2011) |
| "Ketamine pretreatment was administered by intraperitoneal injections at doses of 100, 50, 12." | 1.36 | Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats. ( Alarcón-Galván, G; Ballesteros-Elizondo, RG; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-De La Garza, FJ, 2010) |
| "Premature infants experience untreated repetitive pain that may alter their brain development." | 1.34 | Ketamine reduces the cell death following inflammatory pain in newborn rat brain. ( Anand, KJ; Bhutta, AT; Garg, S; Hall, RW; Narsinghani, U; Rovnaghi, CR, 2007) |
| "Inflammation was induced with a unilateral subcutaneous injection of Car in a plantar hindpaw in rats fed without (control group) or with (deficiency group) a polyamine-deficient diet." | 1.33 | An evaluation of a polyamine-deficient diet for the treatment of inflammatory pain. ( Ecoffey, C; Estebe, JP; Gentili, M; Leduc, C; Legay, F; Moulinoux, JP; Wodey, E, 2006) |
| "Pretreatment with ketamine caused a significant (P < 0." | 1.30 | Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. ( Anderson, JL; Hill, GE; Lyden, ER, 1998) |
| "Ketamine is a widely used general anaesthetic, which has been reported to inhibit neutrophil function and neutrophil-endothelial interaction." | 1.30 | Ketamine does not inhibit inflammatory responses of cultured human endothelial cells but reduces chemotactic activation of neutrophils. ( Becker, BF; Heindl, B; Zahler, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.23) | 18.7374 |
| 1990's | 4 (4.30) | 18.2507 |
| 2000's | 12 (12.90) | 29.6817 |
| 2010's | 50 (53.76) | 24.3611 |
| 2020's | 24 (25.81) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 3 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Li, M | 2 |
| Xue, Y | 1 |
| Li, A | 1 |
| Liu, Y | 9 |
| Zhang, Q | 5 |
| Friesner, I | 1 |
| Jee, HJ | 1 |
| Chen, ZS | 1 |
| Wang, J | 10 |
| Abelaira, HM | 2 |
| Rosa, T | 1 |
| de Moura, AB | 2 |
| Andrade, NM | 1 |
| Martinello, NS | 1 |
| Maciel, LR | 1 |
| Botelho, MEM | 1 |
| Borba, LA | 1 |
| Chede, BC | 1 |
| Arent, CO | 1 |
| Joaquim, L | 1 |
| Bonfante, S | 1 |
| Danielski, LG | 2 |
| Tuon, T | 1 |
| Petronilho, F | 3 |
| Quevedo, J | 2 |
| Réus, GZ | 3 |
| Chen, X | 4 |
| Zhang, Z | 4 |
| Shen, M | 1 |
| Ma, X | 2 |
| Qiu, D | 1 |
| Li, S | 8 |
| Gao, L | 1 |
| Langhein, M | 1 |
| Seitz-Holland, J | 1 |
| Lyall, AE | 1 |
| Pasternak, O | 1 |
| Chunga, N | 1 |
| Cetin-Karayumak, S | 1 |
| Kubicki, A | 1 |
| Mulert, C | 1 |
| Espinoza, RT | 1 |
| Narr, KL | 1 |
| Kubicki, M | 1 |
| Ma, L | 3 |
| Wang, L | 5 |
| Chang, L | 4 |
| Shan, J | 2 |
| Qu, Y | 5 |
| Wang, X | 5 |
| Fujita, Y | 3 |
| Hashimoto, K | 9 |
| Sukhram, SD | 1 |
| Yilmaz, G | 1 |
| Gu, J | 1 |
| Yost, JG | 1 |
| Browne, CA | 1 |
| Lucki, I | 1 |
| Xiao, S | 1 |
| Zhou, Y | 4 |
| Wang, Q | 4 |
| Yang, D | 2 |
| Johnston, JN | 1 |
| Greenwald, MS | 1 |
| Henter, ID | 1 |
| Kraus, C | 1 |
| Mkrtchian, A | 1 |
| Clark, NG | 1 |
| Park, LT | 1 |
| Gold, P | 1 |
| Zarate, CA | 1 |
| Kadriu, B | 1 |
| Halaris, A | 1 |
| Cook, J | 1 |
| Subramanian, S | 1 |
| Oughli, HA | 1 |
| Gebara, MA | 1 |
| Palanca, BJA | 1 |
| Lenze, EJ | 1 |
| Zhou, X | 2 |
| Li, Q | 1 |
| Luo, Q | 1 |
| Chen, J | 5 |
| Xiong, Y | 1 |
| Wu, G | 3 |
| Liu, P | 1 |
| Shu, H | 1 |
| Olié, E | 2 |
| Lengvenyte, A | 2 |
| Courtet, P | 2 |
| Mastrodonato, A | 1 |
| Cohensedgh, O | 1 |
| LaGamma, CT | 1 |
| McGowan, JC | 1 |
| Hunsberger, HC | 1 |
| Denny, CA | 1 |
| Ji, MH | 1 |
| Zhang, L | 4 |
| Mao, MJ | 1 |
| Zhang, H | 3 |
| Yang, JJ | 2 |
| Qiu, LL | 1 |
| Wang, T | 3 |
| Zhu, H | 1 |
| Hou, Y | 1 |
| Duan, W | 2 |
| Meng, F | 1 |
| Wang, Z | 5 |
| Xu, Z | 1 |
| Wu, Y | 4 |
| Li, X | 5 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 2 |
| Zhao, Y | 3 |
| Huang, L | 3 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Wang, B | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 4 |
| Sun, Q | 2 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 5 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 7 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 4 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 10 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 2 |
| Huang, X | 2 |
| Xu, H | 3 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 3 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 2 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
| Tang, LF | 1 |
| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
| Wang, LF | 1 |
| Qiu, SW | 1 |
| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 4 |
| Chu, S | 1 |
| Pan, Q | 1 |
| Li, D | 2 |
| Zheng, S | 2 |
| Hu, T | 1 |
| Wang, F | 1 |
| Han, Z | 1 |
| Yin, Z | 1 |
| Ge, X | 2 |
| Xie, K | 1 |
| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
| Benjelloun, M | 1 |
| Errachidi, F | 1 |
| Cassar, M | 1 |
| Law, AD | 1 |
| Chow, ES | 1 |
| Giebultowicz, JM | 1 |
| Kretzschmar, D | 1 |
| Salonurmi, T | 1 |
| Nabil, H | 1 |
| Ronkainen, J | 1 |
| Hyötyläinen, T | 1 |
| Hautajärvi, H | 1 |
| Savolainen, MJ | 1 |
| Tolonen, A | 1 |
| Orešič, M | 1 |
| Känsäkoski, P | 1 |
| Rysä, J | 1 |
| Hakkola, J | 1 |
| Hukkanen, J | 1 |
| Zhu, N | 1 |
| Li, Y | 5 |
| Du, Q | 1 |
| Hao, P | 1 |
| Cao, X | 1 |
| Li, CX | 1 |
| Zhao, S | 1 |
| Luo, XM | 1 |
| Feng, JX | 1 |
| Gonzalez-Cotto, M | 1 |
| Guo, L | 1 |
| Karwan, M | 1 |
| Sen, SK | 1 |
| Barb, J | 1 |
| Collado, CJ | 1 |
| Elloumi, F | 1 |
| Palmieri, EM | 1 |
| Boelte, K | 1 |
| Kolodgie, FD | 1 |
| Finn, AV | 1 |
| Biesecker, LG | 1 |
| McVicar, DW | 1 |
| Qu, F | 1 |
| Deng, Z | 1 |
| Xie, Y | 2 |
| Tang, J | 3 |
| Chen, Z | 2 |
| Luo, W | 1 |
| Xiong, D | 1 |
| Zhao, D | 1 |
| Fang, J | 1 |
| Zhou, Z | 2 |
| Niu, PP | 1 |
| Song, B | 1 |
| Xu, YM | 1 |
| Qiu, N | 1 |
| Yin, J | 1 |
| Zhang, J | 4 |
| Guo, W | 1 |
| Liu, M | 2 |
| Liu, T | 2 |
| Chen, D | 5 |
| Luo, K | 1 |
| He, Z | 2 |
| Zheng, G | 1 |
| Xu, F | 1 |
| Sun, W | 1 |
| Yin, F | 1 |
| van Hest, JCM | 1 |
| Du, L | 2 |
| Shi, X | 1 |
| Kang, S | 1 |
| Zhang, S | 2 |
| Feng, J | 3 |
| Qi, N | 1 |
| Shen, G | 1 |
| Ren, H | 1 |
| Shang, Q | 1 |
| Zhao, W | 2 |
| Yang, Z | 2 |
| Jiang, X | 2 |
| Alame, M | 1 |
| Cornillot, E | 1 |
| Cacheux, V | 1 |
| Tosato, G | 1 |
| Four, M | 1 |
| De Oliveira, L | 1 |
| Gofflot, S | 1 |
| Delvenne, P | 1 |
| Turtoi, E | 1 |
| Cabello-Aguilar, S | 1 |
| Nishiyama, M | 1 |
| Turtoi, A | 1 |
| Costes-Martineau, V | 1 |
| Colinge, J | 1 |
| Guo, Q | 1 |
| Quan, M | 1 |
| Dong, J | 1 |
| Bai, J | 1 |
| Han, R | 1 |
| Cai, Y | 1 |
| Lv, YQ | 1 |
| Chen, Q | 1 |
| Lyu, HD | 1 |
| Deng, L | 1 |
| Zhou, D | 1 |
| Xiao, X | 1 |
| De Langhe, S | 1 |
| Billadeau, DD | 1 |
| Lou, Z | 1 |
| Zhang, JS | 1 |
| Xue, Z | 1 |
| Shen, XD | 1 |
| Gao, F | 1 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Ji, H | 1 |
| Otano, I | 1 |
| Alvarez, M | 1 |
| Minute, L | 1 |
| Ochoa, MC | 1 |
| Migueliz, I | 1 |
| Molina, C | 1 |
| Azpilikueta, A | 1 |
| de Andrea, CE | 1 |
| Etxeberria, I | 1 |
| Sanmamed, MF | 1 |
| Teijeira, Á | 1 |
| Berraondo, P | 1 |
| Melero, I | 1 |
| Zhong, Z | 1 |
| Xie, X | 1 |
| Yu, Q | 1 |
| Zhou, C | 1 |
| Liu, C | 3 |
| Liu, W | 1 |
| Chen, W | 1 |
| Yin, Y | 1 |
| Li, CW | 1 |
| Hsu, JL | 1 |
| Zhou, Q | 2 |
| Hu, B | 1 |
| Fu, P | 1 |
| Atyah, M | 1 |
| Ma, Q | 2 |
| Xu, Y | 1 |
| Dong, Q | 1 |
| Hung, MC | 1 |
| Ren, N | 1 |
| Huang, P | 1 |
| Liao, R | 1 |
| Cao, Q | 1 |
| Yuan, X | 2 |
| Nie, W | 1 |
| Yang, J | 3 |
| Shao, B | 1 |
| Bi, Z | 1 |
| Liang, X | 1 |
| Tie, Y | 1 |
| Mo, F | 1 |
| Xie, D | 1 |
| Wei, Y | 1 |
| Wei, X | 2 |
| Dokla, EME | 1 |
| Fang, CS | 1 |
| Chu, PC | 1 |
| Chang, CS | 1 |
| Abouzid, KAM | 1 |
| Chen, CS | 1 |
| Blaszczyk, R | 1 |
| Brzezinska, J | 1 |
| Dymek, B | 1 |
| Stanczak, PS | 1 |
| Mazurkiewicz, M | 1 |
| Olczak, J | 1 |
| Nowicka, J | 1 |
| Dzwonek, K | 1 |
| Zagozdzon, A | 1 |
| Golab, J | 1 |
| Golebiowski, A | 1 |
| Xin, Z | 1 |
| Himmelbauer, MK | 1 |
| Jones, JH | 1 |
| Enyedy, I | 1 |
| Gilfillan, R | 1 |
| Hesson, T | 1 |
| King, K | 1 |
| Marcotte, DJ | 1 |
| Murugan, P | 1 |
| Santoro, JC | 1 |
| Gonzalez-Lopez de Turiso, F | 1 |
| Pedron, J | 1 |
| Boudot, C | 1 |
| Brossas, JY | 1 |
| Pinault, E | 1 |
| Bourgeade-Delmas, S | 1 |
| Sournia-Saquet, A | 1 |
| Boutet-Robinet, E | 1 |
| Destere, A | 1 |
| Tronnet, A | 1 |
| Bergé, J | 1 |
| Bonduelle, C | 1 |
| Deraeve, C | 1 |
| Pratviel, G | 1 |
| Stigliani, JL | 1 |
| Paris, L | 1 |
| Mazier, D | 1 |
| Corvaisier, S | 1 |
| Since, M | 1 |
| Malzert-Fréon, A | 1 |
| Wyllie, S | 1 |
| Milne, R | 1 |
| Fairlamb, AH | 1 |
| Valentin, A | 1 |
| Courtioux, B | 1 |
| Verhaeghe, P | 1 |
| Fang, X | 1 |
| Gao, M | 1 |
| Gao, H | 1 |
| Bi, W | 1 |
| Tang, H | 1 |
| Cui, Y | 1 |
| Fan, H | 1 |
| Yu, H | 1 |
| Mathison, CJN | 1 |
| Chianelli, D | 1 |
| Rucker, PV | 1 |
| Nelson, J | 1 |
| Roland, J | 1 |
| Huang, Z | 2 |
| Xie, YF | 1 |
| Epple, R | 1 |
| Bursulaya, B | 1 |
| Lee, C | 1 |
| Gao, MY | 1 |
| Shaffer, J | 1 |
| Briones, S | 1 |
| Sarkisova, Y | 1 |
| Galkin, A | 1 |
| Li, N | 1 |
| Li, C | 2 |
| Hua, S | 1 |
| Kasibhatla, S | 1 |
| Kinyamu-Akunda, J | 1 |
| Kikkawa, R | 1 |
| Molteni, V | 1 |
| Tellew, JE | 1 |
| Jin, X | 1 |
| Pang, B | 1 |
| Liu, Q | 2 |
| Liu, X | 3 |
| Huang, Y | 2 |
| Josephine Fauci, A | 1 |
| Ma, Y | 1 |
| Soo Lee, M | 1 |
| Yuan, W | 1 |
| Gao, R | 1 |
| Qi, H | 1 |
| Zheng, W | 1 |
| Yang, F | 2 |
| Chua, H | 1 |
| Wang, K | 1 |
| Ou, Y | 1 |
| Huang, M | 1 |
| Zhu, Y | 1 |
| Yu, J | 1 |
| Tian, J | 1 |
| Zhao, M | 1 |
| Hu, J | 1 |
| Yao, C | 1 |
| Zhang, B | 1 |
| Usawachintachit, M | 1 |
| Tzou, DT | 1 |
| Washington, SL | 1 |
| Hu, W | 1 |
| Chi, T | 1 |
| Sorensen, MD | 1 |
| Bailey, MR | 1 |
| Hsi, RS | 1 |
| Cunitz, BW | 1 |
| Simon, J | 1 |
| Wang, YN | 1 |
| Dunmire, BL | 1 |
| Paun, M | 1 |
| Starr, F | 1 |
| Lu, W | 1 |
| Evan, AP | 1 |
| Harper, JD | 1 |
| Han, G | 2 |
| Rodrigues, AE | 1 |
| Fouladvand, F | 1 |
| Falahi, E | 1 |
| Asbaghi, O | 1 |
| Abbasnezhad, A | 1 |
| Anigboro, AA | 1 |
| Avwioroko, OJ | 1 |
| Cholu, CO | 1 |
| Sonei, A | 1 |
| Fazelipour, S | 1 |
| Kanaani, L | 1 |
| Jahromy, MH | 1 |
| Jo, K | 1 |
| Hong, KB | 1 |
| Suh, HJ | 1 |
| Park, JH | 1 |
| Shin, E | 1 |
| Park, E | 1 |
| Kouakou-Kouamé, CA | 1 |
| N'guessan, FK | 1 |
| Montet, D | 1 |
| Djè, MK | 1 |
| Kim, GD | 1 |
| González-Fernández, D | 1 |
| Pons, EDC | 1 |
| Rueda, D | 1 |
| Sinisterra, OT | 1 |
| Murillo, E | 1 |
| Scott, ME | 1 |
| Koski, KG | 1 |
| Shete, PB | 1 |
| Gonzales, R | 1 |
| Ackerman, S | 1 |
| Cattamanchi, A | 1 |
| Handley, MA | 1 |
| Li, XX | 1 |
| Xiao, SZ | 1 |
| Gu, FF | 1 |
| He, WP | 1 |
| Ni, YX | 1 |
| Han, LZ | 1 |
| Heffernan, JK | 1 |
| Valgepea, K | 1 |
| de Souza Pinto Lemgruber, R | 1 |
| Casini, I | 1 |
| Plan, M | 1 |
| Tappel, R | 1 |
| Simpson, SD | 1 |
| Köpke, M | 1 |
| Nielsen, LK | 1 |
| Marcellin, E | 1 |
| Cen, YK | 1 |
| Lin, JG | 1 |
| Wang, YL | 2 |
| Wang, JY | 1 |
| Liu, ZQ | 1 |
| Zheng, YG | 1 |
| Spirk, D | 1 |
| Noll, S | 1 |
| Burnier, M | 1 |
| Rimoldi, S | 1 |
| Noll, G | 1 |
| Sudano, I | 1 |
| Penzhorn, BL | 1 |
| Oosthuizen, MC | 1 |
| Kobos, LM | 1 |
| Alqatani, S | 1 |
| Ferreira, CR | 1 |
| Aryal, UK | 1 |
| Hedrick, V | 1 |
| Sobreira, TJP | 1 |
| Shannahan, JH | 1 |
| Gale, P | 1 |
| Singhroy, DN | 1 |
| MacLean, E | 1 |
| Kohli, M | 1 |
| Lessem, E | 1 |
| Branigan, D | 1 |
| England, K | 1 |
| Suleiman, K | 1 |
| Drain, PK | 1 |
| Ruhwald, M | 1 |
| Schumacher, S | 1 |
| Denkinger, CM | 1 |
| Waning, B | 1 |
| Van Gemert, W | 1 |
| Pai, M | 1 |
| Myers, RK | 1 |
| Bonsu, JM | 1 |
| Carey, ME | 1 |
| Yerys, BE | 1 |
| Mollen, CJ | 1 |
| Curry, AE | 1 |
| Douglas, TA | 1 |
| Alinezhadbalalami, N | 1 |
| Balani, N | 1 |
| Schmelz, EM | 1 |
| Davalos, RV | 1 |
| Kamaldinov, T | 1 |
| Erndt-Marino, J | 1 |
| Levin, M | 1 |
| Kaplan, DL | 1 |
| Hahn, MS | 1 |
| Heidarimoghadam, R | 1 |
| Farmany, A | 1 |
| Lee, JJ | 1 |
| Kang, J | 1 |
| Park, S | 1 |
| Cho, JH | 1 |
| Oh, S | 1 |
| Park, DJ | 1 |
| Perez-Maldonado, R | 1 |
| Cho, JY | 1 |
| Park, IH | 1 |
| Kim, HB | 1 |
| Song, M | 1 |
| Mfarrej, B | 1 |
| Jofra, T | 1 |
| Morsiani, C | 1 |
| Gagliani, N | 1 |
| Fousteri, G | 1 |
| Battaglia, M | 1 |
| Giuliano, C | 1 |
| Levinger, I | 1 |
| Vogrin, S | 1 |
| Neil, CJ | 1 |
| Allen, JD | 1 |
| Lv, Y | 1 |
| Yuan, R | 1 |
| Cai, B | 1 |
| Bahrami, B | 1 |
| Chowdhury, AH | 1 |
| Yang, C | 8 |
| Qiao, Q | 1 |
| Liu, SF | 1 |
| Zhang, WH | 1 |
| Kolano, L | 1 |
| Knappe, D | 1 |
| Volke, D | 1 |
| Sträter, N | 1 |
| Hoffmann, R | 1 |
| Coussens, M | 1 |
| Calders, P | 1 |
| Lapauw, B | 1 |
| Celie, B | 1 |
| Banica, T | 1 |
| De Wandele, I | 1 |
| Pacey, V | 1 |
| Malfait, F | 1 |
| Rombaut, L | 1 |
| Vieira, D | 1 |
| Angel, S | 1 |
| Honjol, Y | 1 |
| Gruenheid, S | 1 |
| Gbureck, U | 1 |
| Harvey, E | 1 |
| Merle, G | 1 |
| Seo, G | 1 |
| Lee, G | 1 |
| Kim, MJ | 1 |
| Baek, SH | 1 |
| Choi, M | 1 |
| Ku, KB | 1 |
| Lee, CS | 1 |
| Jun, S | 1 |
| Park, D | 1 |
| Kim, HG | 1 |
| Kim, SJ | 1 |
| Lee, JO | 1 |
| Kim, BT | 1 |
| Park, EC | 1 |
| Kim, SI | 1 |
| Ende, M | 1 |
| Kirkkala, T | 1 |
| Loitzenbauer, M | 1 |
| Talla, D | 1 |
| Wildner, M | 1 |
| Miletich, R | 1 |
| Criado, A | 1 |
| Lavela, P | 1 |
| Tirado, JL | 1 |
| Pérez-Vicente, C | 1 |
| Kang, D | 1 |
| Feng, D | 2 |
| Fang, Z | 1 |
| Wei, F | 1 |
| De Clercq, E | 1 |
| Pannecouque, C | 1 |
| Zhan, P | 1 |
| Guo, Y | 1 |
| Shen, Y | 1 |
| Kawazoe, Y | 1 |
| Jena, P | 1 |
| Sun, Z | 1 |
| Li, Z | 2 |
| Liang, H | 1 |
| Xu, X | 1 |
| Ma, G | 1 |
| Huo, X | 1 |
| Church, JS | 1 |
| Chace-Donahue, F | 1 |
| Blum, JL | 1 |
| Ratner, JR | 1 |
| Zelikoff, JT | 1 |
| Schwartzer, JJ | 1 |
| Fiseha, T | 1 |
| Tamir, Z | 1 |
| Yao, W | 1 |
| Wang, P | 1 |
| Mi, K | 1 |
| Cheng, J | 1 |
| Gu, C | 1 |
| Huang, J | 2 |
| Sun, HB | 1 |
| Xing, WQ | 1 |
| Liu, XB | 1 |
| Zheng, Y | 1 |
| Yang, SJ | 1 |
| Wang, ZF | 1 |
| Liu, SL | 1 |
| Ba, YF | 1 |
| Zhang, RX | 1 |
| Liu, BX | 1 |
| Fan, CC | 1 |
| Chen, PN | 1 |
| Liang, GH | 1 |
| Yu, YK | 1 |
| Wang, HR | 1 |
| Li, HM | 1 |
| Li, ZX | 1 |
| Lalani, SS | 1 |
| Anasir, MI | 1 |
| Poh, CL | 1 |
| Khan, IT | 1 |
| Nadeem, M | 1 |
| Imran, M | 1 |
| Khalique, A | 1 |
| Raspini, B | 1 |
| Porri, D | 1 |
| De Giuseppe, R | 1 |
| Chieppa, M | 1 |
| Liso, M | 1 |
| Cerbo, RM | 1 |
| Civardi, E | 1 |
| Garofoli, F | 1 |
| Monti, MC | 1 |
| Vacca, M | 1 |
| De Angelis, M | 1 |
| Cena, H | 1 |
| Kong, D | 1 |
| Han, X | 1 |
| Xue, H | 1 |
| Zhang, W | 2 |
| Ruan, Z | 1 |
| Noer, PR | 1 |
| Kjaer-Sorensen, K | 1 |
| Juhl, AK | 1 |
| Goldstein, A | 1 |
| Ke, C | 1 |
| Oxvig, C | 1 |
| Duan, C | 1 |
| Kong, F | 1 |
| Lin, S | 1 |
| Bhattacharya, R | 1 |
| Mazumder, D | 1 |
| Yan, X | 1 |
| Ma, C | 1 |
| Tang, Y | 1 |
| Kong, X | 1 |
| Lu, J | 1 |
| Zhang, M | 1 |
| Vital-Jacome, M | 1 |
| Cazares-Granillo, M | 1 |
| Carrillo-Reyes, J | 1 |
| Buitron, G | 1 |
| Jacob, SI | 1 |
| Douair, I | 1 |
| Maron, L | 1 |
| Ménard, G | 1 |
| Rusjan, P | 1 |
| Sabioni, P | 1 |
| Di Ciano, P | 1 |
| Mansouri, E | 1 |
| Boileau, I | 1 |
| Laveillé, A | 1 |
| Capet, M | 1 |
| Duvauchelle, T | 1 |
| Schwartz, JC | 1 |
| Robert, P | 1 |
| Le Foll, B | 1 |
| Xia, Y | 1 |
| Chen, S | 1 |
| Luo, M | 1 |
| Wu, J | 1 |
| Cai, S | 1 |
| He, Y | 2 |
| Garbacz, P | 1 |
| Misiak, M | 1 |
| Jackowski, K | 1 |
| Yuan, Q | 1 |
| Sherrell, PC | 1 |
| Bi, X | 1 |
| Nutho, B | 1 |
| Mahalapbutr, P | 1 |
| Hengphasatporn, K | 1 |
| Pattaranggoon, NC | 1 |
| Simanon, N | 1 |
| Shigeta, Y | 1 |
| Hannongbua, S | 1 |
| Rungrotmongkol, T | 1 |
| Caffrey, PJ | 1 |
| Kher, R | 1 |
| Bian, K | 1 |
| Delaney, S | 1 |
| Xue, J | 1 |
| Wu, P | 2 |
| Xu, L | 1 |
| Yuan, Y | 1 |
| Luo, J | 2 |
| Ye, S | 1 |
| Ustriyana, P | 1 |
| Wei, B | 1 |
| Raee, E | 1 |
| Hu, Y | 1 |
| Wesdemiotis, C | 1 |
| Sahai, N | 1 |
| Kaur, A | 1 |
| Nigam, K | 1 |
| Srivastava, S | 1 |
| Tyagi, A | 1 |
| Dang, S | 1 |
| Millar, JE | 1 |
| Bartnikowski, N | 1 |
| Passmore, MR | 1 |
| Obonyo, NG | 1 |
| Malfertheiner, MV | 1 |
| von Bahr, V | 1 |
| Redd, MA | 1 |
| See Hoe, L | 1 |
| Ki, KK | 1 |
| Pedersen, S | 1 |
| Boyle, AJ | 1 |
| Baillie, JK | 1 |
| Shekar, K | 1 |
| Palpant, N | 1 |
| Suen, JY | 1 |
| Matthay, MA | 1 |
| McAuley, DF | 1 |
| Fraser, JF | 1 |
| Settles, JA | 1 |
| Gerety, GF | 1 |
| Spaepen, E | 1 |
| Suico, JG | 1 |
| Child, CJ | 1 |
| Oh, BL | 1 |
| Lee, JS | 1 |
| Lee, EY | 1 |
| Lee, HY | 1 |
| Yu, HG | 1 |
| Leslie, I | 1 |
| Boos, LA | 1 |
| Larkin, J | 1 |
| Pickering, L | 1 |
| Lima, HK | 1 |
| Vogel, K | 1 |
| Hampel, D | 1 |
| Wagner-Gillespie, M | 1 |
| Fogleman, AD | 1 |
| Ferraz, SL | 1 |
| O'Connor, M | 1 |
| Mazzucchelli, TG | 1 |
| Kajiyama, H | 1 |
| Suzuki, S | 1 |
| Shimbo, A | 1 |
| Utsumi, F | 1 |
| Yoshikawa, N | 1 |
| Kikkawa, F | 1 |
| Javvaji, PK | 1 |
| Dhali, A | 1 |
| Francis, JR | 1 |
| Kolte, AP | 1 |
| Roy, SC | 1 |
| Selvaraju, S | 1 |
| Mech, A | 1 |
| Sejian, V | 1 |
| DeSilva, S | 1 |
| Vaidya, SS | 1 |
| Mao, C | 1 |
| Akhatayeva, Z | 1 |
| Cheng, H | 1 |
| Zhang, G | 2 |
| Jiang, F | 1 |
| Meng, X | 1 |
| Elnour, IE | 1 |
| Lan, X | 1 |
| Song, E | 1 |
| Rohde, S | 1 |
| Antonides, CFJ | 1 |
| Muslem, R | 1 |
| de Woestijne, PCV | 1 |
| der Meulen, MHV | 1 |
| Kraemer, US | 1 |
| Dalinghaus, M | 1 |
| Bogers, AJJC | 1 |
| Pourmand, A | 1 |
| Ghassemi, M | 1 |
| Sumon, K | 1 |
| Amini, SB | 1 |
| Hood, C | 1 |
| Sikka, N | 1 |
| Duan, H | 1 |
| Chen, WP | 1 |
| Fan, M | 1 |
| Wang, WP | 1 |
| Yu, L | 1 |
| Tan, SJ | 1 |
| Xin, S | 1 |
| Wan, LJ | 1 |
| Guo, YG | 1 |
| Tanda, S | 1 |
| Gingl, K | 1 |
| Ličbinský, R | 1 |
| Hegrová, J | 1 |
| Goessler, W | 1 |
| Li, ZL | 1 |
| Zhou, YL | 1 |
| Yan, W | 1 |
| Luo, L | 1 |
| Su, ZZ | 1 |
| Fan, MZ | 1 |
| Wang, SR | 1 |
| Zhao, WG | 1 |
| Xu, D | 1 |
| Hassan, HM | 1 |
| Jiang, Z | 1 |
| Bachmann, KF | 1 |
| Haenggi, M | 1 |
| Jakob, SM | 1 |
| Takala, J | 1 |
| Gattinoni, L | 1 |
| Berger, D | 1 |
| Bentley, RF | 1 |
| Vecchiarelli, E | 1 |
| Banks, L | 1 |
| Gonçalves, PEO | 1 |
| Thomas, SG | 1 |
| Goodman, JM | 1 |
| Mather, K | 1 |
| Boachie, R | 1 |
| Anini, Y | 1 |
| Panahi, S | 1 |
| Anderson, GH | 1 |
| Luhovyy, BL | 1 |
| Nafie, MS | 1 |
| Arafa, K | 1 |
| Sedky, NK | 1 |
| Alakhdar, AA | 1 |
| Arafa, RK | 1 |
| Fan, S | 1 |
| Hu, H | 1 |
| Liang, J | 1 |
| Hu, BC | 1 |
| Wen, Z | 1 |
| Hu, D | 1 |
| Liu, YY | 1 |
| Chu, Q | 1 |
| Wu, MC | 1 |
| Lu, X | 1 |
| Wang, D | 1 |
| Hu, M | 1 |
| Shen, H | 1 |
| Yao, M | 1 |
| Dahlgren, RA | 1 |
| Vysloužil, J | 1 |
| Kulich, P | 1 |
| Zeman, T | 1 |
| Vaculovič, T | 1 |
| Tvrdoňová, M | 1 |
| Mikuška, P | 1 |
| Večeřa, Z | 1 |
| Stráská, J | 1 |
| Moravec, P | 1 |
| Balcar, VJ | 1 |
| Šerý, O | 1 |
| Qiao, L | 1 |
| Xiong, X | 1 |
| Peng, X | 1 |
| Zheng, J | 1 |
| Duan, J | 1 |
| Xiao, W | 1 |
| Zhou, HY | 1 |
| Sui, ZY | 1 |
| Zhao, FL | 1 |
| Sun, YN | 1 |
| Wang, HY | 1 |
| Han, BH | 1 |
| Jintao, X | 1 |
| Shasha, Y | 1 |
| Jincai, W | 1 |
| Chunyan, L | 1 |
| Mengya, Y | 1 |
| Yongli, S | 1 |
| Rasoanirina, BNV | 1 |
| Lassoued, MA | 1 |
| Miladi, K | 1 |
| Razafindrakoto, Z | 1 |
| Chaâbane-Banaoues, R | 1 |
| Ramanitrahasimbola, D | 1 |
| Cornet, M | 1 |
| Sfar, S | 1 |
| Liang, C | 1 |
| Xing, Q | 1 |
| Yi, JL | 1 |
| Zhang, YQ | 1 |
| Li, CY | 1 |
| Tang, SJ | 1 |
| Gao, C | 1 |
| Sun, X | 1 |
| Peng, M | 1 |
| Sun, XF | 1 |
| Zhang, T | 1 |
| Shi, JH | 1 |
| Liao, CX | 1 |
| Gao, WJ | 1 |
| Sun, LL | 1 |
| Gao, Y | 1 |
| Cao, WH | 1 |
| Lyu, J | 1 |
| Yu, CQ | 1 |
| Wang, SF | 1 |
| Pang, ZC | 1 |
| Cong, LM | 1 |
| Dong, Z | 1 |
| Wu, F | 1 |
| Wu, XP | 1 |
| Jiang, GH | 1 |
| Wang, XJ | 1 |
| Wang, BY | 1 |
| Li, LM | 1 |
| Pan, L | 1 |
| Wan, SP | 1 |
| Yi, HWL | 1 |
| He, HJ | 1 |
| Yong, ZP | 1 |
| Shan, GL | 1 |
| Weng, TT | 1 |
| Yan, SQ | 1 |
| Gao, GP | 1 |
| Wei, C | 1 |
| Tao, FB | 1 |
| Shao, ZH | 1 |
| Yao, T | 1 |
| Dong, S | 1 |
| Shi, S | 1 |
| Feng, YL | 1 |
| Zhang, YW | 1 |
| Wang, SP | 1 |
| Shi, AX | 1 |
| Operario, D | 1 |
| Zhang, ZH | 1 |
| Zhu, XF | 1 |
| Zaller, N | 1 |
| Gao, P | 1 |
| Sun, YH | 1 |
| Zhang, HB | 1 |
| Alqahtani, F | 1 |
| Assiri, MA | 1 |
| Mohany, M | 1 |
| Imran, I | 1 |
| Javaid, S | 1 |
| Rasool, MF | 1 |
| Shakeel, W | 1 |
| Sivandzade, F | 1 |
| Alanazi, AZ | 1 |
| Al-Rejaie, SS | 1 |
| Alshammari, MA | 1 |
| Alasmari, F | 1 |
| Alanazi, MM | 1 |
| Alamri, FF | 1 |
| Sedky, AA | 1 |
| Magdy, Y | 1 |
| Kopra, E | 1 |
| Mondelli, V | 1 |
| Pariante, C | 1 |
| Nikkheslat, N | 1 |
| Jiang, R | 3 |
| Wu, Z | 2 |
| Huang, C | 1 |
| Yang, L | 3 |
| Zhu, B | 4 |
| Yan, E | 1 |
| Hashimoto, Y | 1 |
| Wan, X | 1 |
| Kiraly, DD | 1 |
| Horn, SR | 1 |
| Van Dam, NT | 1 |
| Costi, S | 1 |
| Schwartz, J | 1 |
| Kim-Schulze, S | 1 |
| Patel, M | 1 |
| Hodes, GE | 1 |
| Russo, SJ | 1 |
| Merad, M | 1 |
| Iosifescu, DV | 1 |
| Charney, DS | 1 |
| Murrough, JW | 1 |
| Rajandram, R | 1 |
| Yap, NY | 1 |
| Ong, TA | 1 |
| Mun, KS | 1 |
| Mohamad Wali, HA | 1 |
| Hasan, MS | 1 |
| Razack, AHA | 1 |
| Ali Mohd, M | 1 |
| Lee, YL | 2 |
| Lin, KL | 1 |
| Chuang, SM | 1 |
| Lee, YC | 1 |
| Lu, MC | 1 |
| Wu, BN | 1 |
| Wu, WJ | 1 |
| Yuan, SF | 1 |
| Ho, WT | 1 |
| Juan, YS | 1 |
| Matias, BI | 1 |
| Maciel, AL | 1 |
| Ignácio, ZM | 1 |
| Matos, D | 1 |
| Carvalho, AF | 1 |
| Simões, LR | 1 |
| Sangiogo, G | 1 |
| Tashiro, MH | 1 |
| Generoso, JS | 1 |
| Faller, CJ | 1 |
| Dominguini, D | 1 |
| Mastella, GA | 1 |
| Scaini, G | 1 |
| Giridharan, VV | 1 |
| Michels, M | 1 |
| Florentino, D | 1 |
| Dal-Pizzol, F | 1 |
| Zugno, AI | 1 |
| Barichello, T | 1 |
| Kim, ID | 1 |
| Lee, H | 1 |
| Kim, SW | 1 |
| Lee, HK | 1 |
| Han, PL | 1 |
| Lee, JK | 1 |
| Yamaguchi, JI | 2 |
| Toki, H | 2 |
| Koike, H | 1 |
| Mizuno-Yasuhira, A | 2 |
| Chaki, S | 3 |
| Aguilar-Valles, A | 1 |
| Haji, N | 1 |
| De Gregorio, D | 1 |
| Matta-Camacho, E | 1 |
| Eslamizade, MJ | 1 |
| Popic, J | 1 |
| Sharma, V | 1 |
| Cao, R | 1 |
| Rummel, C | 1 |
| Tanti, A | 1 |
| Wiebe, S | 1 |
| Nuñez, N | 1 |
| Comai, S | 1 |
| Nadon, R | 1 |
| Luheshi, G | 1 |
| Mechawar, N | 1 |
| Turecki, G | 1 |
| Lacaille, JC | 1 |
| Gobbi, G | 1 |
| Sonenberg, N | 1 |
| Cui, W | 1 |
| Ning, Y | 1 |
| Hong, W | 1 |
| Li, MD | 1 |
| Chen, MH | 1 |
| Li, CT | 1 |
| Lin, WC | 1 |
| Hong, CJ | 1 |
| Tu, PC | 1 |
| Bai, YM | 1 |
| Cheng, CM | 1 |
| Su, TP | 1 |
| Huang, N | 2 |
| Hua, D | 2 |
| Zhan, G | 2 |
| Bi, J | 1 |
| Luo, A | 2 |
| Zou, H | 1 |
| Wang, LX | 1 |
| Wang, M | 1 |
| Cheng, C | 1 |
| Shen, Q | 1 |
| Fang, L | 1 |
| Liu, R | 1 |
| Xiong, Z | 1 |
| Zhang, K | 1 |
| Pu, Y | 1 |
| Ma, M | 1 |
| Jia, L | 1 |
| Verdonk, F | 1 |
| Petit, AC | 1 |
| Abdel-Ahad, P | 1 |
| Vinckier, F | 1 |
| Jouvion, G | 1 |
| de Maricourt, P | 1 |
| De Medeiros, GF | 1 |
| Danckaert, A | 1 |
| Van Steenwinckel, J | 1 |
| Blatzer, M | 1 |
| Maignan, A | 1 |
| Langeron, O | 1 |
| Sharshar, T | 1 |
| Callebert, J | 1 |
| Launay, JM | 1 |
| Chrétien, F | 1 |
| Gaillard, R | 1 |
| Yu, F | 1 |
| Hua, F | 1 |
| De Kock, M | 2 |
| Loix, S | 1 |
| Lavand'homme, P | 1 |
| Zhu, P | 1 |
| Zhao, Z | 1 |
| Jiang, RY | 1 |
| Shen, J | 1 |
| Hong, T | 1 |
| Liu, N | 1 |
| Ding, LC | 1 |
| Wang, DM | 1 |
| Chen, LJ | 1 |
| Xu, B | 1 |
| Thackeray, JT | 1 |
| Bankstahl, JP | 1 |
| Wollert, KC | 1 |
| Bengel, FM | 1 |
| Chen, JQ | 1 |
| Wen, LY | 1 |
| Miao, JZ | 1 |
| Hu, YM | 1 |
| Xue, R | 1 |
| Li, P | 1 |
| Hao, X | 1 |
| Wei, K | 1 |
| Min, S | 1 |
| Xie, F | 1 |
| Jin, J | 1 |
| Chang, EI | 1 |
| Zárate, MA | 1 |
| Rabaglino, MB | 1 |
| Richards, EM | 1 |
| Keller-Wood, M | 1 |
| Wood, CE | 1 |
| Duman, RS | 1 |
| Aghajanian, GK | 1 |
| Sanacora, G | 1 |
| Krystal, JH | 1 |
| Zhang, GF | 1 |
| Han, JF | 1 |
| Guo, J | 1 |
| Xie, ZM | 1 |
| Pan, W | 1 |
| Sun, KJ | 1 |
| Abe, M | 1 |
| Nozawa, D | 1 |
| Wu, Q | 1 |
| Chen, Y | 1 |
| Zhao, J | 1 |
| Lee, KW | 1 |
| Kim, WB | 1 |
| Lee, SW | 1 |
| Kim, JH | 1 |
| Kim, JM | 1 |
| Kim, YH | 1 |
| Kim, ME | 1 |
| Idell, RD | 1 |
| Florova, G | 1 |
| Komissarov, AA | 1 |
| Shetty, S | 1 |
| Girard, RB | 1 |
| Idell, S | 1 |
| Burgos, E | 1 |
| Pascual, D | 1 |
| Martín, MI | 1 |
| Goicoechea, C | 1 |
| Garrido-Suárez, BB | 1 |
| Garrido, G | 1 |
| Márquez, L | 1 |
| Martínez, I | 1 |
| Hernández, I | 1 |
| Merino, N | 1 |
| Luque, Y | 1 |
| Delgado, R | 1 |
| Bosch, F | 1 |
| Lee, FP | 1 |
| Shih, CM | 1 |
| Shen, HY | 1 |
| Chen, CM | 2 |
| Ko, WC | 1 |
| Whitaker, AM | 1 |
| Sulzer, J | 1 |
| Walker, E | 1 |
| Mathis, K | 1 |
| Molina, PE | 1 |
| Al-Mousawi, AM | 1 |
| Kulp, GA | 1 |
| Branski, LK | 1 |
| Kraft, R | 1 |
| Mecott, GA | 1 |
| Williams, FN | 1 |
| Herndon, DN | 1 |
| Jeschke, MG | 1 |
| Guzmán-De La Garza, FJ | 1 |
| Cámara-Lemarroy, CR | 1 |
| Ballesteros-Elizondo, RG | 1 |
| Alarcón-Galván, G | 1 |
| Cordero-Pérez, P | 1 |
| Fernández-Garza, NE | 1 |
| Welters, ID | 1 |
| Feurer, MK | 1 |
| Preiss, V | 1 |
| Müller, M | 1 |
| Scholz, S | 1 |
| Kwapisz, M | 1 |
| Mogk, M | 1 |
| Neuhäuser, C | 1 |
| Le Roy, C | 1 |
| Laboureyras, E | 1 |
| Gavello-Baudy, S | 1 |
| Chateauraynaud, J | 1 |
| Laulin, JP | 1 |
| Simonnet, G | 1 |
| D'Alonzo, RC | 1 |
| Bennett-Guerrero, E | 2 |
| Podgoreanu, M | 1 |
| D'Amico, TA | 1 |
| Harpole, DH | 1 |
| Shaw, AD | 1 |
| Boegel, K | 1 |
| Gyulai, FE | 1 |
| Moore, KK | 1 |
| Gold, MS | 1 |
| Bhutta, AT | 2 |
| Schmitz, ML | 1 |
| Swearingen, C | 1 |
| James, LP | 1 |
| Wardbegnoche, WL | 1 |
| Lindquist, DM | 1 |
| Glasier, CM | 1 |
| Tuzcu, V | 1 |
| Prodhan, P | 1 |
| Dyamenahalli, U | 1 |
| Imamura, M | 1 |
| Jaquiss, RD | 1 |
| Anand, KJ | 2 |
| Bigham, C | 1 |
| Jaggar, S | 1 |
| DU, J | 1 |
| Huang, YG | 1 |
| Yu, XR | 1 |
| Zhao, N | 1 |
| Floerchinger, B | 1 |
| Jurisch, A | 1 |
| Timsit, MO | 1 |
| Schmid, C | 1 |
| Tullius, SG | 1 |
| Fortis, S | 1 |
| Spieth, PM | 1 |
| Lu, WY | 1 |
| Parotto, M | 1 |
| Haitsma, JJ | 1 |
| Slutsky, AS | 1 |
| Zhong, N | 1 |
| Mazer, CD | 1 |
| Dale, O | 1 |
| Somogyi, AA | 1 |
| Sullivan, T | 1 |
| Shavit, Y | 1 |
| Tsao, CM | 1 |
| Wu, CC | 1 |
| Zhou, ZQ | 1 |
| Lv, R | 1 |
| Li, WY | 1 |
| Xu, JG | 1 |
| Jochem, J | 1 |
| Duan, M | 1 |
| Lin, N | 1 |
| Bartoc, C | 1 |
| Frumento, RJ | 1 |
| Jalbout, M | 1 |
| Du, E | 1 |
| Nishanian, E | 1 |
| Estebe, JP | 1 |
| Legay, F | 1 |
| Gentili, M | 1 |
| Wodey, E | 1 |
| Leduc, C | 1 |
| Ecoffey, C | 1 |
| Moulinoux, JP | 1 |
| Song, XM | 1 |
| Li, JG | 1 |
| Du, ZH | 1 |
| Jia, BH | 1 |
| Ke, JJ | 1 |
| Garg, S | 1 |
| Rovnaghi, CR | 1 |
| Narsinghani, U | 1 |
| Hall, RW | 1 |
| Lois, F | 1 |
| Moore, TC | 1 |
| Pedersen, JL | 1 |
| Galle, TS | 1 |
| Kehlet, H | 1 |
| Hill, GE | 1 |
| Anderson, JL | 1 |
| Lyden, ER | 1 |
| Zahler, S | 1 |
| Heindl, B | 1 |
| Becker, BF | 1 |
| Kawamata, T | 1 |
| Omote, K | 1 |
| Sonoda, H | 1 |
| Kawamata, M | 1 |
| Namiki, A | 1 |
| Rivot, JP | 1 |
| Montagne-Clavel, J | 1 |
| Besson, JM | 1 |
| Guo, H | 1 |
| Li, QJ | 1 |
| Lu, GW | 1 |
| Barbieri, EJ | 1 |
| Ciaccio, EI | 1 |
| Ren, K | 1 |
| Williams, GM | 1 |
| Hylden, JL | 1 |
| Ruda, MA | 1 |
| Dubner, R | 1 |
| Carlson, RP | 1 |
| Datko, LJ | 1 |
| O'Neill-Davis, L | 1 |
| Blazek, EM | 1 |
| DeLustro, F | 1 |
| Beideman, R | 1 |
| Lewis, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Music as a Potential Intervention to Improve Hemodynamic Tolerability of Repetitive Sub-Anesthetic IV Ketamine Infusions in Bipolar and Unipolar Depression: A Pilot Study[NCT04701866] | 32 participants (Actual) | Interventional | 2021-01-11 | Completed | |||
| Prediction of the Therapeutic Response in Depression Based on an Early Neuro-computational Modeling Assessment of Motivation[NCT05866575] | 136 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting | |||
| A Double-blinded, Randomized Placebo-controlled Trial of 40 Hz Light Neurostimulation Therapy for Patients With Depression[NCT05680220] | 60 participants (Anticipated) | Interventional | 2023-02-28 | Not yet recruiting | |||
| Assessment of Efficacy and Safety of Anodal Transcranial Direct Current Stimulation (TDCS) in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemics[NCT04780152] | Phase 2/Phase 3 | 172 participants (Anticipated) | Interventional | 2021-10-31 | Recruiting | ||
| Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery:a Single Center, Randomized, Controlled Trial[NCT04873479] | 50 participants (Anticipated) | Interventional | 2021-05-10 | Recruiting | |||
| Is The Pre-Emptive Administration Of Ketamine A Significant Adjunction To Intravenous Morphine Analgesia For Controlling Post-Operative Pain? A Randomized, Double Blind, Placebo Controlled Clinical Trial.[NCT03415191] | 75 participants (Actual) | Interventional | 2012-01-05 | Completed | |||
| Use of Ketamine Prior to Cardiopulmonary Bypass in Children[NCT00556361] | Phase 2 | 24 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| Ketofol vs Dexmedetomidine for Preventing Post-operative Delirium in Elderly Patients Undergoing Intestinal Obstruction Surgeries. A Randomized Controlled Study[NCT04816162] | Phase 4 | 120 participants (Actual) | Interventional | 2021-03-25 | Completed | ||
| Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia Using Filaments, an Algometer, and Interleukins: a Double-blind, Randomized Study[NCT01301079] | Phase 3 | 60 participants (Actual) | Interventional | 2010-09-30 | Completed | ||
| The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery[NCT02782429] | Phase 4 | 50 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | ||
| Ketamine In Thoracic Surgery (KITS) Trial[NCT00504725] | Phase 2 | 40 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411] | Phase 2 | 80 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions[NCT02512055] | Phase 4 | 33 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery (VATS) - A Randomized Controlled Trial.[NCT03809442] | Phase 4 | 120 participants (Anticipated) | Interventional | 2019-06-25 | Recruiting | ||
| Plasma Concentrations of Ketamine and Norketamine in Patients Using Topical Application of 10% Ketamine for Neuropathic Pain.[NCT01385904] | 15 participants (Anticipated) | Observational | 2011-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The evaluations using the soft brush were performed 2-3 cm from the incision in the periumbilical region (where the large trocar was placed) 24 h after the procedure (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Saline | 0 |
The evaluations using the soft brush were performed 2-3 cm from the incision in the periumbilical region (where the large trocar was placed) before the procedure (NCT01301079)
Timeframe: Before the procedure (Baseline)
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Saline | 0 |
The evaluations using the soft brush were performed in the thenar eminence of the non dominant hand 24 h after the procedure (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Saline | 3 |
The evaluations using the soft brush were performed in the thenar eminence of the nondominant hand before the procedure (NCT01301079)
Timeframe: Before the procedure (Baseline)
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Saline | 0 |
The 300-g filament was used 24 hours after the operation to induce a stimulus and delineate the extent of hyperalgesia from the periumbilical region. The stimulus was started outside the periumbilical region, where no pain sensation was reported, and continued every 0.5 cm until the 4 points of the periumbilical scar were reached (top, right side, left side, and bottom). The first point where the patient complained of pain was marked. If no pain sensation was reported, the stimulus was terminated 0.5 cm from the incision. The distance of each point from the surgical incision was measured, and the sum of the distances of the points was determined. (NCT01301079)
Timeframe: 24 hours after the procedure
| Intervention | centimeter (Mean) |
|---|---|
| Ketamine | 10.61 |
| Saline | 11.82 |
The mechanical pain threshold was evaluated using an algometer. The pressure was increased by 0.1 kgf/second until the patient complained of pain. The mean of three determinations was calculated. (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | kilogram force/second (Mean) |
|---|---|
| Ketamine | 3.5 |
| Saline | 3.7 |
The mechanical pain threshold was evaluated using an algometer. The pressure was increased by 0.1 kgf/second until the patient complained of pain. The mean of three determinations was calculated. (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | kilogram force/second (Mean) |
|---|---|
| Ketamine | 0.56 |
| Saline | 0.51 |
The pain threshold was assessed using six von Frey monofilaments (0,05 g; 0,2 g; 2 g; 4 g; 10 g e 300 g) in the periumbilical region in the postoperative period (24h after the procedure). The use of different von Frey monofilaments, starting with the lightest and ending with the heaviest, was separated by at least 30 seconds to reduce any anticipated responses due to a new stimulation that was performed too soon after the preceding stimulation. Three assessments were made for each monofilament, and this was considered positive when the patient responded to two of the determinations for each monofilament. (NCT01301079)
Timeframe: 24h after the procedure
| Intervention | gram (Mean) |
|---|---|
| Ketamine | 248 |
| Saline | 205 |
The pain threshold was assessed using six von Frey monofilaments (0,05 g; 0,2 g; 2 g; 4 g; 10 g e 300 g) in thenar eminence in the postoperative period (24 hours after procedure). The use of different von Frey monofilaments, starting with the lightest and ending with the heaviest, was separated by at least 30 seconds to reduce any anticipated responses due to a new stimulation that was performed too soon after the preceding stimulation. Three assessments were made for each monofilament, and this was considered positive when the patient responded to two of the determinations for each monofilament. (NCT01301079)
Timeframe: 24 hours after procedure
| Intervention | gram (Mean) |
|---|---|
| Ketamine | 290 |
| Saline | 247 |
The mechanical pain threshold was evaluated using an algometer. The pressure was increased by 0.1 kgf/second until the patient complained of pain. The mean of three determinations was calculated. (NCT01301079)
Timeframe: Baseline (before the surgery)
| Intervention | kilogram force/second (Mean) |
|---|---|
| Ketamine | 3.6 |
| Saline | 3.9 |
The mechanical pain threshold was evaluated using an algometer. The pressure was increased by 0.1 kgf/second until the patient complained of pain. The mean of three determinations was calculated. (NCT01301079)
Timeframe: Baseline (before the procedure)
| Intervention | kilogram force/second (Mean) |
|---|---|
| Ketamine | 2.51 |
| Saline | 2.19 |
The pain threshold was assessed using six von Frey monofilaments (0,05 g; 0,2 g; 2 g; 4 g; 10 g e 300 g) in the periumbilical region in the preoperative period. The use of different von Frey monofilaments, starting with the lightest and ending with the heaviest, was separated by at least 30 seconds to reduce any anticipated responses due to a new stimulation that was performed too soon after the preceding stimulation. Three assessments were made for each monofilament, and this was considered positive when the patient responded to two of the determinations for each monofilament. (NCT01301079)
Timeframe: Before the procedure (Baseline)
| Intervention | gram (Mean) |
|---|---|
| Ketamine | 279 |
| Saline | 269 |
The pain threshold was assessed using six von Frey monofilaments (0,05 g; 0,2 g; 2 g; 4 g; 10 g e 300 g) in thenar eminence in the preoperative period. The use of different von Frey monofilaments, starting with the lightest and ending with the heaviest, was separated by at least 30 seconds to reduce any anticipated responses due to a new stimulation that was performed too soon after the preceding stimulation. Three assessments were made for each monofilament, and this was considered positive when the patient responded to two of the determinations for each monofilament. (NCT01301079)
Timeframe: Before the procedure (Baseline)
| Intervention | gram (Mean) |
|---|---|
| Ketamine | 300 |
| Saline | 300 |
(NCT01301079)
Timeframe: 24 hours
| Intervention | milligram (Mean) |
|---|---|
| Ketamine | 27.40 |
| Saline | 27.70 |
The scale measure pain after 12 hours (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 12 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.6 |
| Saline | 1.4 |
The scale measure pain after 120 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 120 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 2.2 |
| Saline | 2.0 |
The scale measure pain after 150 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 150 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.4 |
| Saline | 1.4 |
The scale measure pain after 18 hours (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 18 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.5 |
| Saline | 1.3 |
The scale measure pain after 180 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 180 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.1 |
| Saline | 1.3 |
The scale measure pain after 210 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 210 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 0.9 |
| Saline | 1.2 |
The scale measure pain after 24 hours (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.4 |
| Saline | 0.8 |
The scale measure pain after 240 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 240 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 1.0 |
| Saline | 1.1 |
The scale measure pain after 30 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 5.5 |
| Saline | 6.2 |
The scale measure pain after 6 hours (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 6 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 0.9 |
| Saline | 0.7 |
The scale measure pain after 60 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 60 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 4.6 |
| Saline | 5.1 |
The scale measure pain after 90 minutes (0 - without pain and 10 worst pain possible). The individual can choose any number between 0 - 10. (NCT01301079)
Timeframe: 90 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.4 |
| Saline | 3.4 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 24 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-6 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 8.6 |
| Saline | 5.0 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 5 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-10 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 5h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 9.1 |
| Saline | 5.5 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes before the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-6 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: Baseline (Before the procedure)
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 7.8 |
| Saline | 1.9 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 24 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-6 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 24.1 |
| Saline | 24.8 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 5 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-6 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 5 h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 29.3 |
| Saline | 34.8 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes before the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-6 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: Baseline (Before the procedure)
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 3.3 |
| Saline | 2.1 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 24 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-8 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 24 h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 6.0 |
| Saline | 4.5 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes 5 h after the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-8 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: 5 h after the procedure
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 8.0 |
| Saline | 11.3 |
Blood samples were drawn in ethylenediaminetetraacetic acid (EDTA) tubes before the surgery. The blood was centrifuged to separate the plasma and was stored at -70°C. IL-8 was analyzed using the enzyme-linked immunosorbent assay (ELISA) methodology. (NCT01301079)
Timeframe: Baseline (Before the procedure)
| Intervention | picogram/milliliter (Mean) |
|---|---|
| Ketamine | 3.3 |
| Saline | 2.2 |
(NCT01301079)
Timeframe: 24 hours
| Intervention | minutes (Median) |
|---|---|
| Ketamine | 18 |
| Saline | 15 |
The CRP levels were measured 24 hours postoperatively. (NCT00504725)
Timeframe: 24 hours
| Intervention | pg/ml (Mean) |
|---|---|
| Ketamine | 8.8 |
| Placebo | 9.3 |
(NCT00504725)
Timeframe: 24 Hours
| Intervention | pg/ml (Mean) | ||
|---|---|---|---|
| Interleukin-6 (IL-6) | Interleukin-8 (IL-8) | Interleukin-10 (IL-10) | |
| Ketamine | 245 | 11.3 | 3.0 |
| Placebo | 269 | 14.8 | 4.9 |
Pain scores rated by the subject on a scale of 0 low - 10 high (NCT00504725)
Timeframe: baseline, 4 hours, 24 hours and at discharge
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| Baseline | 4 Hours | 24 Hours | Discharge | |
| Ketamine | 0.30 | 3.8 | 2.6 | 1.8 |
| Placebo | 0.35 | 3.1 | 2.8 | 1.1 |
11 reviews available for ketamine and Innate Inflammatory Response
| Article | Year |
|---|---|
Antidepressant Effect of Ketamine on Inflammation-Mediated Cytokine Dysregulation in Adults with Treatment-Resistant Depression: Rapid Systematic Review.
Topics: Adult; Antidepressive Agents; Biomarkers; Cytokines; Depression; Depressive Disorder, Major; Humans; | 2022 |
Inflammation, stress and depression: An exploration of ketamine's therapeutic profile.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Depression; Inflammation; Ketamine | 2023 |
Treatment-Resistant Late-Life Depression: A Review of Clinical Features, Neuropsychology, Neurobiology, and Treatment.
Topics: Aged; Alzheimer Disease; Anxiety; Depressive Disorder, Treatment-Resistant; Diagnosis, Differential; | 2023 |
Suicide Has Many Faces, So Does Ketamine: a Narrative Review on Ketamine's Antisuicidal Actions.
Topics: Antidepressive Agents; Humans; Inflammation; Ketamine; Neuronal Plasticity; Pain; Reward; Suicidal I | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Ketamine's effect on inflammation and kynurenine pathway in depression: A systematic review.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Bipolar Disorder; Cytokines; Depressive Di | 2021 |
Crosstalk Between Inflammation and Glutamate System in Depression: Signaling Pathway and Molecular Biomarkers for Ketamine's Antidepressant Effect.
Topics: Animals; Antidepressive Agents; Biomarkers; Depression; Glutamic Acid; Humans; Inflammation; Ketamin | 2019 |
Ketamine and peripheral inflammation.
Topics: Analgesics; Animals; Cognition Disorders; Humans; Inflammation; Ketamine; Pain; Postoperative Compli | 2013 |
Inflammatory biomarkers as differential predictors of antidepressant response.
Topics: Antidepressive Agents; Biomarkers; C-Reactive Protein; Cytokines; Depressive Disorder, Major; Humans | 2015 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interleukin-6; Intraoperative Care; Ketamine; Postop | 2012 |
Something new about ketamine for pediatric anesthesia?
Topics: Analgesia; Anesthesia; Anesthetics, Dissociative; Animals; Humans; Hyperalgesia; Inflammation; Ketam | 2008 |
10 trials available for ketamine and Innate Inflammatory Response
| Article | Year |
|---|---|
Association between peripheral inflammation and free-water imaging in Major Depressive Disorder before and after ketamine treatment - A pilot study.
Topics: Depressive Disorder, Major; Humans; Inflammation; Interleukin-10; Interleukin-8; Ketamine; Pilot Pro | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Rapid inflammation modulation and antidepressant efficacy of a low-dose ketamine infusion in treatment-resistant depression: A randomized, double-blind control study.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Treatment-Resistant; Dose-Response Relationship, | 2018 |
Preoperative and postoperative analgesic techniques in the treatment of patients undergoing transabdominal hysterectomy: a preliminary randomized trial.
Topics: Adult; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combi | 2015 |
Continuous S-(+)-ketamine administration during elective coronary artery bypass graft surgery attenuates pro-inflammatory cytokine response during and after cardiopulmonary bypass.
Topics: Aged; Analgesics; Anesthesia, General; Cardiopulmonary Bypass; Coronary Artery Bypass; Cytokines; Fe | 2011 |
A randomized, double blind, placebo controlled clinical trial of the preoperative use of ketamine for reducing inflammation and pain after thoracic surgery.
Topics: Aged; Analgesics; C-Reactive Protein; Double-Blind Method; Female; Humans; Inflammation; Interleukin | 2011 |
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
Topics: Anti-Inflammatory Agents; Biomarkers; Brain; Brain Injuries; C-Reactive Protein; Cardiopulmonary Byp | 2012 |
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
Topics: Anti-Inflammatory Agents; Biomarkers; Brain; Brain Injuries; C-Reactive Protein; Cardiopulmonary Byp | 2012 |
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
Topics: Anti-Inflammatory Agents; Biomarkers; Brain; Brain Injuries; C-Reactive Protein; Cardiopulmonary Byp | 2012 |
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: a pilot randomized, double-blind, placebo-controlled trial.
Topics: Anti-Inflammatory Agents; Biomarkers; Brain; Brain Injuries; C-Reactive Protein; Cardiopulmonary Byp | 2012 |
Effects of preoperative ketamine on the endocrine-metabolic and inflammatory response to laparoscopic surgery.
Topics: Analgesics; Double-Blind Method; Female; Gynecologic Surgical Procedures; Humans; Inflammation; Keta | 2011 |
A randomized, double-blind, placebo-controlled study assessing the anti-inflammatory effects of ketamine in cardiac surgical patients.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Dose-Resp | 2006 |
A randomized, double-blind, placebo-controlled study assessing the anti-inflammatory effects of ketamine in cardiac surgical patients.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Dose-Resp | 2006 |
A randomized, double-blind, placebo-controlled study assessing the anti-inflammatory effects of ketamine in cardiac surgical patients.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Dose-Resp | 2006 |
A randomized, double-blind, placebo-controlled study assessing the anti-inflammatory effects of ketamine in cardiac surgical patients.
Topics: Aged; Biomarkers; C-Reactive Protein; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Dose-Resp | 2006 |
Peripheral analgesic effects of ketamine in acute inflammatory pain.
Topics: Administration, Cutaneous; Adult; Anesthetics, Dissociative; Double-Blind Method; Female; Humans; In | 1998 |
Peripheral analgesic effects of ketamine in acute inflammatory pain.
Topics: Administration, Cutaneous; Adult; Anesthetics, Dissociative; Double-Blind Method; Female; Humans; In | 1998 |
Peripheral analgesic effects of ketamine in acute inflammatory pain.
Topics: Administration, Cutaneous; Adult; Anesthetics, Dissociative; Double-Blind Method; Female; Humans; In | 1998 |
Peripheral analgesic effects of ketamine in acute inflammatory pain.
Topics: Administration, Cutaneous; Adult; Anesthetics, Dissociative; Double-Blind Method; Female; Humans; In | 1998 |
73 other studies available for ketamine and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
The upregulation of Nur77 decreases ketamine-induced hippocampal neurons toxicity in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cytokines; Heme Oxygenase (Decyclizing); Hippocampus | 2021 |
Disrupted population coding in the prefrontal cortex underlies pain aversion.
Topics: Animals; Aversive Agents; Excitatory Amino Acid Antagonists; Inflammation; Ketamine; Male; Neural Pa | 2021 |
Combination of electroconvulsive stimulation with ketamine or escitalopram protects the brain against inflammation and oxidative stress induced by maternal deprivation and is critical for associated behaviors in male and female rats.
Topics: Animals; Behavior, Animal; Brain; Escitalopram; Female; Hippocampus; Inflammation; Ketamine; Male; M | 2022 |
Downregulation of the NLRP3/Caspse-1 Pathway Ameliorates Ketamine-Induced Liver Injury and Inflammation in Developing Rats.
Topics: Animals; Caspase 1; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Down-Re | 2022 |
A role of microRNA-149 in the prefrontal cortex for prophylactic actions of (R)-ketamine in inflammation model.
Topics: Animals; Antagomirs; Antidepressive Agents; Inflammation; Ketamine; Lipopolysaccharides; Male; Mice; | 2022 |
(2R,6R)-hydroxynorketamine (HNK) reverses mechanical hypersensitivity in a model of localized inflammatory pain.
Topics: Animals; Antidepressive Agents; Female; Inflammation; Ketamine; Male; Mice; Mice, Inbred C57BL; Neur | 2022 |
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Kelch-Like ECH- | 2022 |
The Glutamatergic System in Treatment-Resistant Depression and Comparative Effectiveness of Ketamine and Esketamine: Role of Inflammation?
Topics: Antidepressive Agents; Depression; Depressive Disorder, Major; Humans; Inflammation; Ketamine | 2023 |
A single dose of ketamine relieves fentanyl-induced-hyperalgesia by reducing inflammation initiated by the TLR4/NF-κB pathway in rat spinal cord neurons.
Topics: Animals; Cyclooxygenase 2; Fentanyl; Hyperalgesia; Inflammation; Ketamine; Neurons; NF-kappa B; Rats | 2023 |
[How can ketamine be used to manage suicidal risk?]
Topics: Anhedonia; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Hum | 2023 |
Prophylactic (R,S)-ketamine selectively protects against inflammatory stressors.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Conditioning, Classical; Depression; Fear; Inflamm | 2020 |
Overinhibition mediated by parvalbumin interneurons might contribute to depression-like behavior and working memory impairment induced by lipopolysaccharide challenge.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fl | 2020 |
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Topics: Analgesics; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Ketamine; Monocyt | 2020 |
Impact of ketamine on the behavior and immune system of adult medaka (Oryzias latipes) at environmentally relevant concentrations and eco-risk assessment in surface water.
Topics: Animals; Behavior, Animal; Ecotoxicology; Female; Fish Proteins; Gene Expression; Immune System; Inf | 2020 |
Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse Model.
Topics: Animals; Behavior, Animal; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Inflammation; K | 2020 |
Reduction in TNF alpha and oxidative stress by liraglutide: Impact on ketamine-induced cognitive dysfunction and hyperlocomotion in rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Brain-Derived Neurotrophic Factor; Cognition Disorders; Di | 2021 |
Gut microbiota is involved in the antidepressant-like effect of (S)-norketamine in an inflammation model of depression.
Topics: Animals; Antidepressive Agents; Bacteria; Depression; Disease Models, Animal; Gastrointestinal Micro | 2021 |
(R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture.
Topics: Animals; Biomarkers; Cecum; Cytokines; Disease Models, Animal; Inflammation; Inflammation Mediators; | 2021 |
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome.
Topics: Adult; Case-Control Studies; Chemokines; Cytokines; Depressive Disorder, Major; Depressive Disorder, | 2017 |
Oral ketamine induced pathological changes of the urinary tract in a rat model.
Topics: Animals; Inflammation; Ketamine; Kidney; Male; Models, Animal; Rats, Sprague-Dawley; Substance-Relat | 2017 |
Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model.
Topics: Animals; Cystitis; Disease Models, Animal; Female; Hyaluronan Receptors; Hyaluronic Acid; Inflammati | 2017 |
Mechanism of synergistic action on behavior, oxidative stress and inflammation following co-treatment with ketamine and different antidepressant classes.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Drug Synergism; Drug Therapy, Combination; Inflamm | 2017 |
Maternal immune activation induced by lipopolysaccharide triggers immune response in pregnant mother and fetus, and induces behavioral impairment in adult rats.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Cytokines; Embryo, Mammalian; Excitatory Amin | 2018 |
Alarmin HMGB1 induces systemic and brain inflammatory exacerbation in post-stroke infection rat model.
Topics: Animals; Bacterial Infections; Behavior, Animal; Brain; Cyclooxygenase 2; Disease Models, Animal; HM | 2018 |
(2R,6R)-Hydroxynorketamine is not essential for the antidepressant actions of (R)-ketamine in mice.
Topics: Animals; Antidepressive Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; | 2018 |
No Sex-Specific Differences in the Acute Antidepressant Actions of (R)-Ketamine in an Inflammation Model.
Topics: Animals; Brain; Female; Immobility Response, Tonic; Inflammation; Ketamine; Lipopolysaccharides; Mal | 2018 |
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzofurans; Citalopram; Depression; Depr | 2018 |
Role of Actinobacteria and Coriobacteriia in the antidepressant effects of ketamine in an inflammation model of depression.
Topics: Actinobacteria; Animals; Antidepressive Agents; Behavior, Animal; Biomarkers; Depression; Depressive | 2019 |
MTOR-Mediated Autophagy Is Involved in the Protective Effect of Ketamine on Allergic Airway Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Autophagy; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2019 |
Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model.
Topics: Animals; Antidepressive Agents; Biomarkers; Bone Density; Depression; Depressive Disorder; Disease M | 2019 |
Ketamine exerts a protective role in a cell-based model of major depressive disorder via the inhibition of apoptosis and inflammation and activation of the Krebs cycle.
Topics: Adult; Animals; Apoptosis; Cell Survival; Citric Acid Cycle; Cytokines; Depressive Disorder, Major; | 2020 |
Microglial production of quinolinic acid as a target and a biomarker of the antidepressant effect of ketamine.
Topics: Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Biomarkers, Pharmacological; Depression; | 2019 |
Contribution of skeletal muscular glycine to rapid antidepressant effects of ketamine in an inflammation-induced mouse model of depression.
Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Glycine; Inflammation; Ketamine; | 2019 |
Ketamine inhibits calcium elevation and hydroxyl radical and nitric oxide production in lipopolysaccharide-stimulated NR8383 alveolar macrophages.
Topics: Analgesics; Animals; Calcium; Cell Line; Hydroxyl Radical; Inflammation; Interleukin-1beta; Interleu | 2013 |
Ketamine attenuates the lipopolysaccharide-induced inflammatory response in cultured N2a cells.
Topics: Anesthetics, Dissociative; Cell Line; Gene Expression Regulation; Humans; Inflammation; Inflammation | 2013 |
Clinically relevant strategies for lowering cardiomyocyte glucose uptake for 18F-FDG imaging of myocardial inflammation in mice.
Topics: Anesthetics, General; Animals; Anticoagulants; Fasting; Fluorodeoxyglucose F18; Glucose; Heparin; In | 2015 |
Ketamine-mediated alleviation of electroconvulsive shock-induced memory impairment is associated with the regulation of neuroinflammation and soluble amyloid-beta peptide in depressive-like rats.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Depression; Elec | 2015 |
Ketamine attenuates high mobility group box-1-induced inflammatory responses in endothelial cells.
Topics: Anesthetics, Dissociative; Biomarkers; Cell Adhesion; Cell Movement; Cell Survival; Dose-Response Re | 2016 |
Ketamine suppresses hypoxia-induced inflammatory responses in the late-gestation ovine fetal kidney cortex.
Topics: Animals; Chemokines; Excitatory Amino Acid Antagonists; Female; Fetal Hypoxia; Inflammation; Interle | 2016 |
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cytokines; Depressive Disorder; Diabetes M | 2016 |
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cytokines; Depressive Disorder; Diabetes M | 2016 |
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cytokines; Depressive Disorder; Diabetes M | 2016 |
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.
Topics: Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cytokines; Depressive Disorder; Diabetes M | 2016 |
Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Freund's Adjuv | 2016 |
(R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dominance-Subordination | 2017 |
Ketamine Analog Methoxetamine Induced Inflammation and Dysfunction of Bladder in Rats.
Topics: Animals; Body Weight; Cell Line; Chemokines; Cyclohexanones; Cyclohexylamines; Epithelial Cells; Epi | 2017 |
Alterations of Macrophage Migration Inhibitory Factor Expression in the Nervous System of the Rat Cystitis Model.
Topics: Animals; Cystitis; Disease Models, Animal; Female; Immunohistochemistry; Inflammation; Intramolecula | 2017 |
The fibrinolytic system: A new target for treatment of depression with psychedelics.
Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Fibrinolysin; Fibrinolysis; Hallu | 2017 |
Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Anti-Inflammatory Agents, Non-St | 2010 |
Pre-emptive anti-hyperalgesic effect of electroacupuncture in carrageenan-induced inflammation: role of nitric oxide.
Topics: Animals; Carrageenan; Electroacupuncture; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hot | 2009 |
Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia.
Topics: Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Female; Flavonoids; Hypersensi | 2010 |
Sympathetic modulation of the host defense response to infectious challenge during recovery from hemorrhage.
Topics: Animals; Disease Models, Animal; Hemorrhage; Immune Tolerance; Immunity, Innate; Inflammation; Ketam | 2010 |
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
Ketamine reduces intestinal injury and inflammatory cell infiltration after ischemia/reperfusion in rats.
Topics: Analysis of Variance; Animals; Antithrombin III; Disease Models, Animal; Excitatory Amino Acid Antag | 2010 |
Endogenous opioids released during non-nociceptive environmental stress induce latent pain sensitization Via a NMDA-dependent process.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Carrageenan; Disease Models, Animal; Excitatory A | 2011 |
Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, General; Animals; Behavior, Animal; Exc | 2011 |
Ketamine for induction and maintenance during elective on-pump coronary artery bypass grafts.
Topics: Analgesics; Cardiopulmonary Bypass; Coronary Artery Bypass; Female; Humans; Inflammation; Inflammati | 2011 |
Inflammatory immune responses in a reproducible mouse brain death model.
Topics: Anesthesia; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blood Pressure; Brain De | 2012 |
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury.
Topics: Acute Lung Injury; Analysis of Variance; Anesthesia; Anesthetics, Dissociative; Anesthetics, General | 2012 |
Modulating effects of ketamine on inflammatory response in sepsis.
Topics: Apoptosis; Humans; Inflammation; Ketamine; Sepsis | 2012 |
Ketamine inhibits LPS-induced calcium elevation and NF-kappa B activation in monocytes.
Topics: Animals; Calcium; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Endotoxins; Excit | 2004 |
Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino | 2004 |
Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats.
Topics: Animals; Cell Nucleus; Disease Progression; Dose-Response Relationship, Drug; Edema; Endotoxins; Enz | 2005 |
An evaluation of a polyamine-deficient diet for the treatment of inflammatory pain.
Topics: Analgesia; Analgesics; Animals; Carrageenan; Diet; Hindlimb; Hyperalgesia; Inflammation; Ketamine; M | 2006 |
Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats.
Topics: Animals; Bacterial Infections; Cecum; Cytokines; Heart Rate; Hemodynamics; Hypotension; Inflammation | 2006 |
Ketamine reduces the cell death following inflammatory pain in newborn rat brain.
Topics: Analgesics; Animals; Animals, Newborn; Behavior, Animal; Brain; Cell Death; Female; Humans; Infant, | 2007 |
Anesthesia-associated depression in lymphocyte traffic and its modulation.
Topics: Anesthesia, General; Animals; Barbiturates; Bradykinin; Cyclic GMP; Depression, Chemical; Drainage; | 1984 |
Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation.
Topics: Adrenergic beta-Agonists; Anesthetics, Dissociative; Animals; Cell Line; Colforsin; Cyclic AMP; Cyto | 1998 |
Ketamine does not inhibit inflammatory responses of cultured human endothelial cells but reduces chemotactic activation of neutrophils.
Topics: Anesthetics, Dissociative; Cell Adhesion Molecules; Cells, Cultured; Chemotaxis; Chemotaxis, Leukocy | 1999 |
Analgesic mechanisms of ketamine in the presence and absence of peripheral inflammation.
Topics: Adrenergic alpha-Antagonists; Analgesia; Analgesics; Animals; Carrageenan; Drug Administration Sched | 2000 |
Subcutaneous formalin and intraplantar carrageenan increase nitric oxide release as measured by in vivo voltammetry in the spinal cord.
Topics: Animals; Carrageenan; Excitatory Amino Acid Antagonists; Formaldehyde; Inflammation; Inflammation Me | 2002 |
Effects of ketamine on neuronal activity of the spinal dorsal horn in rats with unilateral hindpaw inflammation.
Topics: Animals; Carrageenan; Evoked Potentials; Female; Foot; Inflammation; Ketamine; Neurons; Rats; Recept | 2000 |
Depression of drug metabolism in the mouse by a combination of Mycobacterium butyricum and anaesthetics.
Topics: Anesthetics; Animals; Depression, Chemical; Inflammation; Ketamine; Male; Mixed Function Oxygenases; | 1979 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; C | 1992 |
Comparison of inflammatory changes in established type II collagen- and adjuvant-induced arthritis using outbred Wistar rats.
Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Blood Proteins; Collagen; Copper; D | 1985 |