Page last updated: 2024-10-29

ketamine and Injuries, Multiple

ketamine has been researched along with Injuries, Multiple in 10 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Multimodal therapy encompasses a wide range of procedures and medications, including regional analgesia with continuous epidural or peripheral nerve block infusions, judicious opioids, acetaminophen, anti-inflammatory agents, anticonvulsants, ketamine, clonidine, mexiletine, antidepressants, and anxiolytics as options to treat or modulate pain at various sites of action."4.84The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism. ( Black, IH; Malchow, RJ, 2008)
" For patients with multiple injuries and for those patients requiring manipulation and splintage of fractures and for entrapments and difficult extrications ketamine is a safe and effective option, which avoids the potential decrease in blood pressure and respiratory depression that is associated with opioid analgesia."3.72Ketamine in prehospital care. ( Porter, K, 2004)
"Agitation commonly complicates polytrauma presentations, and is treated according to the danger it presents to patient and staff."3.01Management of Pain and Agitation in Trauma. ( Strayer, RJ, 2023)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Strayer, RJ3
Baekgaard, JS1
Eskesen, TG1
Sillesen, M1
Rasmussen, LS1
Steinmetz, J1
Mcqueen, C1
Pillay, L1
Hardcastle, T1
Malchow, RJ1
Black, IH1
Porter, K1
Melamed, E1
Oron, Y1
Ben-Avraham, R1
Blumenfeld, A1
Lin, G1
Werner, C1
Rauch, DA1
Ursprung, T1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Study of Induction Medications Used in the Rapid Sequence Intubation of Trauma Patients and a Comparison of Effects on Outcomes[NCT04291521]7,000 participants (Anticipated)Observational2024-01-01Not yet recruiting
Comparison of Ultrasound Guided Femoral Nerve Blockade and Standard Parenteral Opioid Pain Management Alone in Patients With Hip Fracture in the Emergency Department[NCT02381717]60 participants (Anticipated)Interventional2015-08-31Recruiting
Managing Acute Pain in Critically Ill Non-communicative Palliative Care Patients[NCT02127086]377 participants (Actual)Interventional2015-03-31Completed
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915]314 participants (Actual)Observational2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for ketamine and Injuries, Multiple

ArticleYear
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Management of Pain and Agitation in Trauma.
    Emergency medicine clinics of North America, 2023, Volume: 41, Issue:1

    Topics: Analgesics, Opioid; Humans; Ketamine; Multiple Trauma; Pain; Propofol

2023
Ketamine as a Rapid Sequence Induction Agent in the Trauma Population: A Systematic Review.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:3

    Topics: Anesthetics, Dissociative; Humans; Ketamine; Length of Stay; Mortality; Multiple Trauma; Observation

2019
Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting).
    World journal of surgery, 2017, Volume: 41, Issue:5

    Topics: Adult; Androstanols; Anesthetics, Dissociative; Anesthetics, Intravenous; Developing Countries; Emer

2017
The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism.
    Critical care medicine, 2008, Volume: 36, Issue:7 Suppl

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Ste

2008
The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism.
    Critical care medicine, 2008, Volume: 36, Issue:7 Suppl

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Ste

2008
The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism.
    Critical care medicine, 2008, Volume: 36, Issue:7 Suppl

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Ste

2008
The evolution of pain management in the critically ill trauma patient: Emerging concepts from the global war on terrorism.
    Critical care medicine, 2008, Volume: 36, Issue:7 Suppl

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Ste

2008
[Ketamine is contraindicated in craniocerebral trauma--fact or fiction?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1994, Volume: 29, Issue:7

    Topics: Anesthesia, General; Animals; Brain Injuries; Cerebrovascular Circulation; Contraindications; Humans

1994

Other Studies

5 other studies available for ketamine and Injuries, Multiple

ArticleYear
Clinical interventions by helicopter emergency medical service teams: Time for key performance indicators?
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2016, Volume: 23, Issue:1

    Topics: Air Ambulances; Conscious Sedation; Critical Illness; Emergency Medical Services; Female; Humans; Ke

2016
Ketamine in prehospital care.
    Emergency medicine journal : EMJ, 2004, Volume: 21, Issue:3

    Topics: Accidents, Traffic; Adolescent; Adult; Aged; Analgesia; Analgesics; Emergency Medical Services; Fema

2004
The combative multitrauma patient: a protocol for prehospital management.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2007, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Dissociative; Behavior Control; Clinical Protocols; Drug Therapy, Co

2007
Use of ketamine in a pain management protocol for repetitive procedures.
    Pediatrics, 1998, Volume: 102, Issue:2 Pt 1

    Topics: Anesthetics, Dissociative; Bandages; Child; Conscious Sedation; Debridement; Drug Therapy, Combinati

1998
[Management of war injuries from the anesthesiologic point of view: a report of experiences from the IKRK hospital in Kabul, September 1990].
    Zeitschrift fur Unfallchirurgie und Versicherungsmedizin : offizielles Organ der Schweizerischen Gesellschaft fur Unfallmedizin und Berufskrankheiten = Revue de traumatologie et d'assicurologie : organe officiel de la Societe suisse de ..., 1991, Volume: 84, Issue:1

    Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Spinal; Child; Female; Humans; Ketamine; Male; M

1991