ketamine has been researched along with Injuries, Leg in 6 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016." | 5.24 | Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures. ( Bryant, KK; Dunn, C; Hogg, M; Moore, CG; Reynolds, SL; Runyon, MS; Studnek, JR; Templin, MA; Walker, KR; Young, JR, 2017) |
| "Ketamine alone did not produce motor block, but addition of adrenaline resulted in complete motor block, and may have intensified sensory blockade." | 1.27 | Intrathecal ketamine for war surgery. A preliminary study under field conditions. ( Bion, JF, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reynolds, SL | 1 |
| Bryant, KK | 1 |
| Studnek, JR | 1 |
| Hogg, M | 1 |
| Dunn, C | 1 |
| Templin, MA | 1 |
| Moore, CG | 1 |
| Young, JR | 1 |
| Walker, KR | 1 |
| Runyon, MS | 1 |
| Graudins, A | 1 |
| Meek, R | 1 |
| Egerton-Warburton, D | 1 |
| Seith, R | 1 |
| Furness, T | 1 |
| Chapman, R | 1 |
| Bion, JF | 1 |
| Vatashsky, E | 1 |
| Aronson, HB | 1 |
| Cottingham, R | 1 |
| Thomson, K | 1 |
| Muncibì, S | 1 |
| Santoni, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321] | Phase 4 | 22 participants (Actual) | Interventional | 2015-05-01 | Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 0 |
| Fentanyl | 0 |
An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.36 |
| Fentanyl | 2.09 |
2 trials available for ketamine and Injuries, Leg
| Article | Year |
|---|---|
Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschoo | 2017 |
The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial.
Topics: Administration, Intranasal; Adolescent; Age Factors; Analgesics; Analgesics, Opioid; Arm Injuries; C | 2013 |
4 other studies available for ketamine and Injuries, Leg
| Article | Year |
|---|---|
Intrathecal ketamine for war surgery. A preliminary study under field conditions.
Topics: Adolescent; Adult; Anesthesia, Spinal; Brain; Cambodia; Female; Hemodynamics; Humans; Ketamine; Leg | 1984 |
Pemphigus vulgaris: anaesthesia in the traumatised patient.
Topics: Adult; Anesthesia, General; Anesthesia, Intravenous; Chronic Disease; Diazepam; Female; Humans; Keta | 1982 |
Use of ketamine in prolonged entrapment.
Topics: Accidents; Accidents, Traffic; Adult; Analgesia; Female; First Aid; Humans; Injections, Intravenous; | 1994 |
[Use of Ketamine in orthopedics and traumatology].
Topics: Adolescent; Adult; Aged; Anesthesia; Arm Injuries; Child; Child, Preschool; Female; Humans; Infant; | 1973 |