ketamine has been researched along with Infarction, Middle Cerebral Artery in 14 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings not only suggest that ketamine represents a viable candidate for the treatment of poststroke depression but also that ketamine's lasting antidepressant effects might be achieved through modulation of NMDAR/CaMKII-induced synaptic plasticity in key brain regions." | 8.02 | Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model. ( Abdoulaye, IA; Cao, XJ; Chibaatar, E; Guo, YJ; Le, K; Wu, SS; Yu, DF, 2021) |
| " Since sedation of animals is necessary to avoid artifacts, a mixture of ketamine and xylazine is frequently used for anesthesia." | 7.72 | Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications. ( Dittmar, MS; Fehm, NP; Horn, M; Vatankhah, B, 2004) |
| " Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)." | 5.17 | Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013) |
| "These findings not only suggest that ketamine represents a viable candidate for the treatment of poststroke depression but also that ketamine's lasting antidepressant effects might be achieved through modulation of NMDAR/CaMKII-induced synaptic plasticity in key brain regions." | 4.02 | Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model. ( Abdoulaye, IA; Cao, XJ; Chibaatar, E; Guo, YJ; Le, K; Wu, SS; Yu, DF, 2021) |
| " Since sedation of animals is necessary to avoid artifacts, a mixture of ketamine and xylazine is frequently used for anesthesia." | 3.72 | Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications. ( Dittmar, MS; Fehm, NP; Horn, M; Vatankhah, B, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 5 (35.71) | 2.80 |
| Authors | Studies |
|---|---|
| Mousavi, SM | 1 |
| Karimi-Haghighi, S | 1 |
| Chavoshinezhad, S | 1 |
| Pandamooz, S | 1 |
| Belém-Filho, IJA | 1 |
| Keshavarz, S | 1 |
| Bayat, M | 1 |
| Hooshmandi, E | 1 |
| Rahimi Jaberi, A | 1 |
| Salehi, MS | 1 |
| Borhani-Haghighi, A | 1 |
| Gu, C | 3 |
| Liu, J | 3 |
| Li, Y | 3 |
| Zhang, Q | 3 |
| Lin, C | 3 |
| Huang, J | 3 |
| Duan, W | 3 |
| Deng, Y | 3 |
| Ahmed, W | 3 |
| Li, R | 3 |
| Long, J | 3 |
| Khan, AA | 3 |
| Chen, L | 3 |
| Chen, G | 1 |
| Kamat, PK | 1 |
| Ahmad, AS | 1 |
| Doré, S | 1 |
| Xiong, Z | 1 |
| Chang, L | 1 |
| Qu, Y | 1 |
| Pu, Y | 1 |
| Wang, S | 1 |
| Fujita, Y | 1 |
| Ishima, T | 1 |
| Chen, J | 1 |
| Hashimoto, K | 1 |
| Abdoulaye, IA | 1 |
| Wu, SS | 1 |
| Chibaatar, E | 1 |
| Yu, DF | 1 |
| Le, K | 1 |
| Cao, XJ | 1 |
| Guo, YJ | 1 |
| Kim, ID | 1 |
| Lee, H | 1 |
| Kim, SW | 1 |
| Lee, HK | 1 |
| Choi, J | 1 |
| Han, PL | 1 |
| Lee, JK | 1 |
| Kalchenko, V | 1 |
| Israeli, D | 1 |
| Kuznetsov, Y | 1 |
| Harmelin, A | 1 |
| Tukhovskaya, EA | 1 |
| Yukin, AY | 1 |
| Khokhlova, ON | 1 |
| Murashev, AN | 1 |
| Vitek, MP | 1 |
| Zhao, H | 1 |
| Mayhan, WG | 1 |
| Sun, H | 1 |
| Gauberti, M | 1 |
| Obiang, P | 1 |
| Guedin, P | 1 |
| Balossier, A | 1 |
| Gakuba, C | 1 |
| Diependaele, AS | 1 |
| Chazalviel, L | 1 |
| Vivien, D | 1 |
| Young, AR | 1 |
| Agin, V | 1 |
| Orset, C | 1 |
| Bleilevens, C | 1 |
| Roehl, AB | 1 |
| Goetzenich, A | 1 |
| Zoremba, N | 1 |
| Kipp, M | 1 |
| Dang, J | 1 |
| Tolba, R | 1 |
| Rossaint, R | 1 |
| Hein, M | 1 |
| Lebedev, SV | 1 |
| Petrov, SV | 1 |
| Blinov, DV | 1 |
| Lazarenko, IP | 1 |
| Chekhonin, VP | 1 |
| Zhang, PB | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Chen, XL | 1 |
| Tian, YF | 1 |
| Sun, JJ | 1 |
| Liu, JX | 1 |
| Dittmar, MS | 1 |
| Fehm, NP | 1 |
| Vatankhah, B | 1 |
| Horn, M | 1 |
1 trial available for ketamine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction; | 2013 |
13 other studies available for ketamine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
The impacts of anesthetic regimens on the middle cerebral artery occlusion outcomes in male rats.
Topics: Anesthetics; Animals; Humans; Infarction, Middle Cerebral Artery; Isoflurane; Ketamine; Male; Rats; | 2022 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model.
Topics: Anesthesia; Animals; Disease Models, Animal; Infarction, Middle Cerebral Artery; Isoflurane; Ketamin | 2023 |
Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke.
Topics: Analgesics; Anesthetics; Animals; Brain Infarction; Brain Ischemia; Extremities; Halothane; Infarcti | 2020 |
Neuronal brain injury after cerebral ischemic stroke is ameliorated after subsequent administration of (R)-ketamine, but not (S)-ketamine.
Topics: Animals; Behavior, Animal; Brain Injuries; Disease Models, Animal; Infarction, Middle Cerebral Arter | 2020 |
Ketamine Induces Lasting Antidepressant Effects by Modulating the NMDAR/CaMKII-Mediated Synaptic Plasticity of the Hippocampal Dentate Gyrus in Depressive Stroke Model.
Topics: Animals; Antidepressive Agents; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dentate Gyrus; D | 2021 |
Alarmin HMGB1 induces systemic and brain inflammatory exacerbation in post-stroke infection rat model.
Topics: Animals; Bacterial Infections; Behavior, Animal; Brain; Cyclooxygenase 2; Disease Models, Animal; HM | 2018 |
Transcranial optical vascular imaging (TOVI) of cortical hemodynamics in mouse brain.
Topics: Animals; Brain; Cerebral Arteries; Cerebrovascular Circulation; Contrast Media; Hemodynamics; Infarc | 2014 |
COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia.
Topics: Animals; Apolipoproteins E; Brain; Disease Models, Animal; Infarction, Middle Cerebral Artery; Ketam | 2009 |
A modified suture technique produces consistent cerebral infarction in rats.
Topics: Analysis of Variance; Anesthetics; Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Mod | 2008 |
Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study.
Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Atracurium; Craniotomy; Dif | 2012 |
Ketamine-induced rotational asymmetry in evaluation of motor disturbances in rats with middle cerebral artery occlusion.
Topics: Animals; Brain; Diagnostic Techniques, Neurological; Excitatory Amino Acid Antagonists; Infarction, | 2003 |
[Effects of ketamine-midazolam anesthesia on focal cerebral ischemic injury in rats].
Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Apoptosis; Infarct | 2004 |
Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications.
Topics: Anesthesia; Anesthetics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Infarcti | 2004 |