ketamine has been researched along with Hypoventilation in 8 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Hypoventilation: A reduction in the amount of air entering the pulmonary alveoli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary objective of this investigation was to examine the effect of ketamine on hypoventilation in patients receiving deep sedation for surgery with midazolam and propofol." | 9.19 | The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial. ( Ahmad, S; De Oliveira, GS; Fitzgerald, PC; Hansen, N; McCarthy, RJ, 2014) |
| "In the dose range of interest for postoperative, intensive-care and pain-clinic settings, ketamine antagonises the resting hypoventilation induced by alfentanil." | 9.09 | Ketamine antagonises alfentanil-induced hypoventilation in healthy male volunteers. ( Björkman, S; Götharson, E; Gustafsson, LL; Hellström, G; Persson, J; Scheinin, H, 1999) |
| "Hypopneic hypoventilation as detected by capnography is common in children undergoing sedation with ketamine with or without midazolam." | 7.77 | Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine. ( Chen, L; Langhan, ML; Marshall, C; Santucci, KA, 2011) |
| " The primary outcome was the occurrence of a respiratory adverse event (desaturation, apnea, or hypoventilation) requiring an intervention by the sedating physician." | 5.22 | Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. ( Bell, A; Ding, M; Ferguson, I; Holdgate, A; New, L; Treston, G, 2016) |
| "Hypopneic hypoventilation as detected by capnography is common in children undergoing sedation with ketamine with or without midazolam." | 3.77 | Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine. ( Chen, L; Langhan, ML; Marshall, C; Santucci, KA, 2011) |
| "We review PPS, cardiac tamponade, and the proper performance of a pericardiocentesis." | 2.42 | Cardiac tamponade complicating postpericardiotomy syndrome. ( Alessandrini, EA; Donoghue, AJ; Scarfone, RJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Oliveira, GS | 1 |
| Fitzgerald, PC | 1 |
| Hansen, N | 1 |
| Ahmad, S | 1 |
| McCarthy, RJ | 1 |
| Ferguson, I | 1 |
| Bell, A | 1 |
| Treston, G | 1 |
| New, L | 1 |
| Ding, M | 1 |
| Holdgate, A | 1 |
| Langhan, ML | 1 |
| Chen, L | 1 |
| Marshall, C | 1 |
| Santucci, KA | 1 |
| Chandrakantan, A | 1 |
| Poulton, TJ | 1 |
| Scarfone, RJ | 1 |
| Donoghue, AJ | 1 |
| Alessandrini, EA | 1 |
| Persson, J | 1 |
| Scheinin, H | 1 |
| Hellström, G | 1 |
| Björkman, S | 1 |
| Götharson, E | 1 |
| Gustafsson, LL | 1 |
| Greene, SA | 1 |
| Thurmon, JC | 1 |
| Tranquilli, WJ | 1 |
| Benson, GJ | 1 |
| Berkebile, PE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Ketamine in The Prevention of Hypoventilation in Patients With and Without a Positive Berlin Questionnaire Undergoing Deep Sedation[NCT01535976] | 54 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Prospective Observational Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio at the Emergency Department of a Tertiary Hospital[NCT04028141] | 61 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| Intravenous Sedation and Analgesia Using Propofol, Fentanyl and Ketamine (PFK) Versus General Anesthesia in Minor Urological Procedures.[NCT04285528] | 200 participants (Actual) | Interventional | 2019-04-17 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Subjects receiving intraoperative ketamine in addition to propofol will demonstrate less hypoventilation during the surgical procedure. (NCT01535976)
Timeframe: 8 hours
| Intervention | % time (Median) |
|---|---|
| Ketamine | 1.2 |
| Placebo | 65 |
2 reviews available for ketamine and Hypoventilation
| Article | Year |
|---|---|
Cardiac tamponade complicating postpericardiotomy syndrome.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Cardiac Tamponade; Child; Child, Preschool; Combined | 2003 |
Postoperative care.
Topics: Ambulatory Care; Anaphylaxis; Anesthesia; Anesthesia, Conduction; Eye Diseases; Heart Diseases; Hear | 1973 |
3 trials available for ketamine and Hypoventilation
| Article | Year |
|---|---|
The effect of ketamine on hypoventilation during deep sedation with midazolam and propofol: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Hypoventilation; Ketamine; Mida | 2014 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Apnea; Deep Sedation; Double-Blind Method; Dr | 2016 |
Ketamine antagonises alfentanil-induced hypoventilation in healthy male volunteers.
Topics: Adult; Alfentanil; Analysis of Variance; Anesthetics, Dissociative; Anesthetics, Intravenous; Carbon | 1999 |
3 other studies available for ketamine and Hypoventilation
| Article | Year |
|---|---|
Detection of hypoventilation by capnography and its association with hypoxia in children undergoing sedation with ketamine.
Topics: Adolescent; Anesthetics, Dissociative; Capnography; Carbon Dioxide; Child; Child, Preschool; Conscio | 2011 |
Anesthetic considerations for rapid-onset obesity, hypoventilation, hypothalamic dysfunction, and autonomic dysfunction (ROHHAD) syndrome in children.
Topics: Adjuvants, Anesthesia; Analgesics; Androstanols; Anesthesia, General; Anesthetics, Inhalation; Atrop | 2013 |
Cardiopulmonary effects of continuous intravenous infusion of guaifenesin, ketamine, and xylazine in ponies.
Topics: Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Guaifenesin; Heart Rate; Horses | 1986 |