ketamine has been researched along with Hemorrhage, Subarachnoid in 7 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption." | 5.46 | Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017) |
| "The available evidence from preclinical studies is helping to translate the role of ketamine in blocking spreading depolarizations to clinical practice, in the settings of migraine with aura, traumatic brain injury, subarachnoid hemorrhage, and hemorrhagic and ischemic stroke." | 5.12 | Cortical spreading depolarization and ketamine: a short systematic review. ( Coelho, ACSDS; Figueiredo, EG; Rabelo, NN; Teixeira, MJ; Telles, JPM; Welling, LC, 2021) |
| " To reach an adequate cerebral perfusion pressure (CPP), the norepinephrine dosage was adapted successively." | 2.73 | Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies: a pilot study. ( Bertsch, T; Horn, P; Muench, E; Quintel, M; Schmittner, MD; Vajkoczy, P; Vajkoczy, SL, 2007) |
| "Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption." | 1.46 | Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Santos, E | 1 |
| Olivares-Rivera, A | 1 |
| Major, S | 1 |
| Sánchez-Porras, R | 2 |
| Uhlmann, L | 1 |
| Kunzmann, K | 1 |
| Zerelles, R | 1 |
| Kentar, M | 1 |
| Kola, V | 1 |
| Aguilera, AH | 1 |
| Herrera, MG | 1 |
| Lemale, CL | 1 |
| Woitzik, J | 1 |
| Hartings, JA | 2 |
| Sakowitz, OW | 2 |
| Unterberg, AW | 1 |
| Dreier, JP | 2 |
| Honore, PM | 1 |
| Mugisha, A | 1 |
| Kugener, L | 1 |
| Redant, S | 1 |
| Attou, R | 1 |
| Gallerani, A | 1 |
| De Bels, D | 1 |
| Telles, JPM | 1 |
| Welling, LC | 1 |
| Coelho, ACSDS | 1 |
| Rabelo, NN | 1 |
| Teixeira, MJ | 1 |
| Figueiredo, EG | 1 |
| Helbok, R | 1 |
| Schiefecker, A | 1 |
| Balança, B | 1 |
| Jewel, S | 1 |
| Foreman, B | 1 |
| Ercole, A | 1 |
| Balu, R | 1 |
| Ayata, C | 1 |
| Ngwenya, L | 1 |
| Rosenthal, E | 1 |
| Boutelle, MG | 1 |
| Farkas, E | 1 |
| Fabricius, M | 1 |
| Shuttleworth, CW | 1 |
| Carlson, A | 1 |
| Zheng, Z | 1 |
| Von der Brelie, C | 1 |
| Seifert, M | 1 |
| Rot, S | 1 |
| Tittel, A | 1 |
| Sanft, C | 1 |
| Meier, U | 1 |
| Lemcke, J | 1 |
| Schmittner, MD | 1 |
| Vajkoczy, SL | 1 |
| Horn, P | 1 |
| Bertsch, T | 1 |
| Quintel, M | 1 |
| Vajkoczy, P | 1 |
| Muench, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Ketamine Sedation Initiated Early After Aneurysmal Subarachnoid Hemorrhage: Effect on Vasospasm, Delayed Cerebral Ischemia, and Functional Outcomes[NCT05032118] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2023-04-27 | Withdrawn (stopped due to Institution change, no IRB approval) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ketamine and Hemorrhage, Subarachnoid
| Article | Year |
|---|---|
Cortical spreading depolarization and ketamine: a short systematic review.
Topics: Animals; Cortical Spreading Depression; Humans; Ketamine; Migraine Disorders; Prospective Studies; R | 2021 |
Pharmacological modulation of spreading depolarizations.
Topics: Amnesia, Transient Global; Animals; Brain Injuries; Cortical Spreading Depression; Excitatory Amino | 2015 |
1 trial available for ketamine and Hemorrhage, Subarachnoid
| Article | Year |
|---|---|
Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies: a pilot study.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Dissociative; Brain Injuries; Cerebrovascular Circulat | 2007 |
4 other studies available for ketamine and Hemorrhage, Subarachnoid
| Article | Year |
|---|---|
Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study.
Topics: Adult; Aged; Cohort Studies; Female; Humans; Hypnotics and Sedatives; Ketamine; Length of Stay; Male | 2019 |
High doses of ketamine to improve neuronal edema in subarachnoid hemorrhage: we should consider other undesirable organ targets.
Topics: Edema; Humans; Ketamine; Retrospective Studies; Subarachnoid Hemorrhage | 2020 |
What Should a Clinician Do When Spreading Depolarizations are Observed in a Patient?
Topics: Brain Injuries, Traumatic; Cortical Spreading Depression; Electrocorticography; Electroencephalograp | 2020 |
Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics; Cerebral Infarction; Comorbidity; Female; | 2017 |