ketamine has been researched along with Hemisensory Neglect in 6 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data were obtained from 110 individuals with mood disorders (predominantly major depressive disorder) who underwent intravenous ketamine infusion." | 7.88 | Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale. ( Davidson, L; Sanacora, G; Silverman, WK; van Schalkwyk, GI; Wilkinson, ST, 2018) |
| "Data were obtained from 110 individuals with mood disorders (predominantly major depressive disorder) who underwent intravenous ketamine infusion." | 3.88 | Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale. ( Davidson, L; Sanacora, G; Silverman, WK; van Schalkwyk, GI; Wilkinson, ST, 2018) |
| "Ketamine induced a range of perceptual distortions, but not hallucinations." | 3.73 | Psychological effects of ketamine in healthy volunteers. Phenomenological study. ( Absalom, AR; Bullmore, ET; Corlett, PR; Fletcher, PC; Honey, GD; Lee, M; McKenna, PJ; Murray, GK; Pomarol-Clotet, E, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Schalkwyk, GI | 1 |
| Wilkinson, ST | 1 |
| Davidson, L | 1 |
| Silverman, WK | 1 |
| Sanacora, G | 1 |
| Liu, L | 1 |
| Wei, ZW | 1 |
| Jia, J | 1 |
| Wang, YJ | 1 |
| Corlett, PR | 2 |
| Honey, GD | 2 |
| Aitken, MR | 1 |
| Dickinson, A | 1 |
| Shanks, DR | 1 |
| Absalom, AR | 2 |
| Lee, M | 2 |
| Pomarol-Clotet, E | 2 |
| Murray, GK | 2 |
| McKenna, PJ | 2 |
| Robbins, TW | 1 |
| Bullmore, ET | 2 |
| Fletcher, PC | 2 |
| Stone, JM | 1 |
| Pilowsky, LS | 1 |
| Anand, A | 1 |
| Charney, DS | 1 |
| Oren, DA | 1 |
| Berman, RM | 1 |
| Hu, XS | 1 |
| Cappiello, A | 1 |
| Krystal, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Music as a Potential Intervention to Improve Hemodynamic Tolerability of Repetitive Sub-Anesthetic IV Ketamine Infusions in Bipolar and Unipolar Depression: A Pilot Study[NCT04701866] | 32 participants (Actual) | Interventional | 2021-01-11 | Completed | |||
| An Investigation of the Antidepressant Efficacy and Safety of an AMPAkine (Org 24448) in Major Depressive Disorder, A Double-Blind, Placebo-Controlled, Randomized Study[NCT00113022] | Phase 2 | 9 participants (Actual) | Interventional | 2005-05-31 | Terminated (stopped due to Terminated due to concerns about adverse events in separate study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The MADRS is a measure of depression severity examined on a weekly basis. The minimum score on the 10 item scale is 0 indicating no depression. The maximum score is 60 indicating a very severe depression. Scores of 18 and above are generally considered to suggest significant levels of depression. (NCT00113022)
Timeframe: 8 weeks
| Intervention | Scores on a scale (Least Squares Mean) |
|---|---|
| Org 24448 | 26.425 |
| Placebo | 24.205 |
2 trials available for ketamine and Hemisensory Neglect
| Article | Year |
|---|---|
Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis.
Topics: Adult; Association Learning; Brief Psychiatric Rating Scale; Cognition Disorders; Delusions; Disease | 2006 |
Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists.
Topics: Adult; Affect; Brief Psychiatric Rating Scale; Cognition Disorders; Double-Blind Method; Excitatory | 2000 |
4 other studies available for ketamine and Hemisensory Neglect
| Article | Year |
|---|---|
Acute psychoactive effects of intravenous ketamine during treatment of mood disorders: Analysis of the Clinician Administered Dissociative State Scale.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Factor Analysis, Statistical; Female; Huma | 2018 |
[Toxicokinetics of ketamine in rabbits].
Topics: Administration, Oral; Anesthetics, Dissociative; Animals; Blood Pressure; Gas Chromatography-Mass Sp | 2010 |
Psychological effects of ketamine in healthy volunteers. Phenomenological study.
Topics: Adult; Brief Psychiatric Rating Scale; Central Nervous System; Cognition Disorders; Delusions; Excit | 2006 |
Psychopathological consequences of ketamine.
Topics: Adult; Brief Psychiatric Rating Scale; Delusions; Excitatory Amino Acid Antagonists; Female; Halluci | 2006 |