Page last updated: 2024-10-29

ketamine and Glycine Encephalopathy

ketamine has been researched along with Glycine Encephalopathy in 3 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Delayed emergence from anesthesia was previously reported in a case study of a child with Glycine Encephalopathy."4.02Elevated preoptic brain activity in zebrafish glial glycine transporter mutants is linked to lethargy-like behaviors and delayed emergence from anesthesia. ( Bindernagel, R; Buglo, E; Dallman, JE; Engert, F; Kelz, MB; Meng, QC; Randlett, O; Sloan, SA; Stark, MJ; Sumathipala, SH; Syed, S; Venincasa, MJ; Yan, Q; Züchner, S, 2021)
"Three of four nonketotic hyperglycinemia patients homozygous for a novel GLDC mutation (A802V) were treated by assisted respiration and/or sodium benzoate with or without ketamine and had transient neonatal or absent symptoms and normal developmental outcome, despite persisting biochemical evidence of nonketotic hyperglycinemia."1.32Persistent NKH with transient or absent symptoms and a homozygous GLDC mutation. ( Boneh, A; Ergaz, Z; Gomori, JM; Gutman, A; Ichinohe, A; Kojima, K; Korman, SH; Kure, S; Sato, K, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Venincasa, MJ1
Randlett, O1
Sumathipala, SH1
Bindernagel, R1
Stark, MJ1
Yan, Q1
Sloan, SA1
Buglo, E1
Meng, QC1
Engert, F1
Züchner, S1
Kelz, MB1
Syed, S1
Dallman, JE1
Korman, SH2
Boneh, A1
Ichinohe, A1
Kojima, K1
Sato, K1
Ergaz, Z1
Gomori, JM1
Gutman, A2
Kure, S2
Wexler, ID1
Rolland, MO1
Kanno, J1

Other Studies

3 other studies available for ketamine and Glycine Encephalopathy

ArticleYear
Elevated preoptic brain activity in zebrafish glial glycine transporter mutants is linked to lethargy-like behaviors and delayed emergence from anesthesia.
    Scientific reports, 2021, 02-04, Volume: 11, Issue:1

    Topics: Aminobenzoates; Anesthesia, General; Anesthetics; Animals; Animals, Genetically Modified; Craniotomy

2021
Persistent NKH with transient or absent symptoms and a homozygous GLDC mutation.
    Annals of neurology, 2004, Volume: 56, Issue:1

    Topics: Adult; Amino Acid Oxidoreductases; Child, Preschool; DNA Mutational Analysis; Excitatory Amino Acid

2004
Treatment from birth of nonketotic hyperglycinemia due to a novel GLDC mutation.
    Annals of neurology, 2006, Volume: 59, Issue:2

    Topics: Aldehydes; Amino Acid Oxidoreductases; Carrier Proteins; DNA Mutational Analysis; Epoxy Compounds; E

2006