ketamine has been researched along with Glaucoma in 16 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of sevoflurane induction, followed by intravenous ketamine infusion on IOP, in children undergoing EUA for glaucoma or suspected glaucoma, and to establish the earliest time point at which reliable, repeatable IOP measurements can be obtained under anaesthesia." | 7.88 | How does sevoflurane induction, followed by a ketamine maintenance infusion, affect intraocular pressure? Establishment of an anaesthetic protocol for paediatric glaucoma examinations under anaesthesia. ( Roodt, F; Tinley, C; van der Walt, JG, 2018) |
| "To determine the effect of sevoflurane induction, followed by intravenous ketamine infusion on IOP, in children undergoing EUA for glaucoma or suspected glaucoma, and to establish the earliest time point at which reliable, repeatable IOP measurements can be obtained under anaesthesia." | 3.88 | How does sevoflurane induction, followed by a ketamine maintenance infusion, affect intraocular pressure? Establishment of an anaesthetic protocol for paediatric glaucoma examinations under anaesthesia. ( Roodt, F; Tinley, C; van der Walt, JG, 2018) |
| "As part of an ophthalmic and anthropometric survey of two free-breeding rhesus monkey (Macaca mulatta) populations, intraocular pressure (IOP) of 114 animals was measured under ketamine catalepsia with the use of a floating-tip pneumatonometer." | 3.66 | Intraocular pressure of rhesus monkey (Macaca mulatta). I. An initial survey of two free-breeding colonies. ( Bito, LZ; DeRousseau, CJ; Merritt, SQ, 1979) |
| " Acepromazine, ketamine, xylazine, droperidol-fentamyl, and combinations of these drugs were evaluated for effects on blood pressure, intraocular pressure, and restraint of the dog for 4 minutes of Schiotz tonography of each eye." | 3.65 | Tonography in the normal and glaucomatous beagle. ( Gelatt, KN; Gum, GG; Gwin, RM; Peiffer, RL, 1977) |
| "Senile glaucoma is a common ophthalmological disease in the elderly." | 1.72 | Explore the molecular mechanism of angle-closure glaucoma in elderly patients induced telomere shortening of retinal ganglion cells through oxidative stress. ( Chen, F; Xia, X; Yan, A; Zhou, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, J | 1 |
| Chen, F | 1 |
| Yan, A | 1 |
| Xia, X | 1 |
| van der Walt, JG | 1 |
| Roodt, F | 1 |
| Tinley, C | 1 |
| Jones, L | 1 |
| Sung, V | 1 |
| Lascaratos, G | 1 |
| Nagi, H | 1 |
| Holder, R | 1 |
| Cone, FE | 1 |
| Steinhart, MR | 1 |
| Oglesby, EN | 1 |
| Kalesnykas, G | 1 |
| Pease, ME | 1 |
| Quigley, HA | 2 |
| Santiveri, X | 1 |
| Moltò, L | 1 |
| Rodríguez, C | 1 |
| Sandín, F | 1 |
| Vilaplana, J | 1 |
| Castillo, J | 1 |
| Blumberg, D | 1 |
| Congdon, N | 1 |
| Jampel, H | 1 |
| Gilbert, D | 1 |
| Elliott, R | 1 |
| Rivers, R | 1 |
| Munoz, B | 1 |
| Quigley, H | 1 |
| Bito, LZ | 1 |
| Merritt, SQ | 1 |
| DeRousseau, CJ | 1 |
| Mathur, GB | 1 |
| Desai, NC | 1 |
| Shreevastava, BB | 1 |
| Gelatt, KN | 1 |
| Gwin, RM | 1 |
| Peiffer, RL | 1 |
| Gum, GG | 1 |
| Marynen, L | 1 |
| Hahnenberger, RW | 1 |
| Heilmann, K | 1 |
| Bolinches Bolinches, R | 1 |
| Moliner Moliner, C | 1 |
| Moratal Juan, B | 1 |
| Adams, AK | 1 |
| Purschke, R | 1 |
| Hassouna, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411] | Phase 2 | 80 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketamine and Glaucoma
| Article | Year |
|---|---|
[Glaucoma, tonometry and anaesthesia (author's transl)].
Topics: Anesthesia; Anesthetics; Blood Pressure; Chronic Disease; Eye; Glaucoma; Humans; Intraocular Pressur | 1975 |
2 trials available for ketamine and Glaucoma
| Article | Year |
|---|---|
[Sedation and analgesia with propofol plus low-dose ketamine for retrobulbar block].
Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Analgesics, Non-Na | 2006 |
The effects of sevoflurane and ketamine on intraocular pressure in children during examination under anesthesia.
Topics: Adolescent; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Blood Pressure; Child; Child, | 2007 |
13 other studies available for ketamine and Glaucoma
| Article | Year |
|---|---|
Explore the molecular mechanism of angle-closure glaucoma in elderly patients induced telomere shortening of retinal ganglion cells through oxidative stress.
Topics: Animals; beta-Galactosidase; Disease Models, Animal; Fluorescent Dyes; Glaucoma; Glaucoma, Angle-Clo | 2022 |
How does sevoflurane induction, followed by a ketamine maintenance infusion, affect intraocular pressure? Establishment of an anaesthetic protocol for paediatric glaucoma examinations under anaesthesia.
Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Blood Pressure; Child; Ch | 2018 |
Intraocular pressures after ketamine and sevoflurane in children with glaucoma undergoing examination under anaesthesia.
Topics: Anesthetics, Dissociative; Anesthetics, Inhalation; Child; Child, Preschool; Female; Glaucoma; Human | 2010 |
The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma.
Topics: Acepromazine; Aging; Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Axons; | 2012 |
Childhood glaucoma: results with trabeculotomy and study of reversible cupping.
Topics: Administration, Topical; Adolescent; Child; Child, Preschool; Follow-Up Studies; Glaucoma; Halothane | 1982 |
Intraocular pressure of rhesus monkey (Macaca mulatta). I. An initial survey of two free-breeding colonies.
Topics: Aging; Animals; Circadian Rhythm; Female; Glaucoma; Haplorhini; Intraocular Pressure; Ketamine; Long | 1979 |
Ketamine hydrochloride (Ketalar) intraocular pressure.
Topics: Adult; Female; Glaucoma; Humans; Intraocular Pressure; Ketamine; Male; Middle Aged | 1977 |
Tonography in the normal and glaucomatous beagle.
Topics: Acepromazine; Animals; Aqueous Humor; Atropine; Blood Pressure; Dog Diseases; Dogs; Droperidol; Drug | 1977 |
Ocular tonometry in the child under general anesthesia with IM ketamine.
Topics: Anesthesia, General; Child; Child, Preschool; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular | 1976 |
Influence of various anesthetic drugs on the intraocular pressure of cats.
Topics: Anesthetics; Animals; Azepines; Cats; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Ket | 1976 |
[Anesthesia in ophthalmic enucleation].
Topics: Adult; Anesthesia, General; Atropine; Child; Child, Preschool; Diazepam; Drug Evaluation; Eye Injuri | 1974 |
Ketamine in paediatric ophthalmic practice.
Topics: Child; Child, Preschool; Glaucoma; Humans; Infant; Intraocular Pressure; Ketamine; Tonometry, Ocular | 1973 |
[The influence of ketamine on intra-ocular pressure (author's transl)].
Topics: Adolescent; Audiometry; Blood Pressure; Child; Child, Preschool; Glaucoma; Heart Rate; Humans; Intra | 1973 |