ketamine has been researched along with Emesis, Postoperative in 75 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After IRB approval and informed consent, 36 patients, aged 10-19 years, undergoing posterior correction surgery for adolescent idiopathic scoliosis, were randomly allocated into two groups: intra- and postoperative ketamine infusion at a rate of 2 μg/kg/min until 48 h after surgery (ketamine group, n = 17) or infusion of an equal volume of saline (placebo group, n = 19)." | 9.20 | Intra- and postoperative low-dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial. ( Hashiguchi, S; Ihara, N; Katori, N; Kosugi, S; Minoshima, R; Morisaki, H; Nishimura, D; Seki, H; Watanabe, K; Yamada, T, 2015) |
| "Ketamine and magnesium association reduces the post-operative morphine consumption after scoliosis surgery." | 9.19 | Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study. ( Abou Zeid, HA; Ghanem, IB; Jabbour, HJ; Jabbour, KB; Jawish, RJ; Naccache, NM; Rabbaa-Khabbaz, LG; Yazbeck, PH, 2014) |
| "To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery." | 9.17 | A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013) |
| "Eighty-four children (aged two to seven years) undergoing elective strabismus surgery under sevoflurane anesthesia were randomly assigned to one of three groups (n = 28 each)." | 9.17 | Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. ( Chen, JY; Jia, JE; Li, WX; Liu, TJ; Qin, MJ, 2013) |
| "Eighty children undertaking strabismus surgery were randomly divided into sevoflurane-N2O inhalation anaesthesia group with LMA (volatile group, n=40) and propofol-ketamine total intravenous anesthesia group (TIVA group, n=40)." | 9.12 | [Sevoflurane-N2O inhalation anaesthesia with laryngeal mask airway and propofol-ketamine intravenous anaesthesia in strabismus surgery]. ( Liu, Y; Zeng, QY, 2006) |
| "To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia." | 8.98 | Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018) |
| "patient-controlled analgesia (IV-PCA) on postoperative nausea and vomiting (PONV) in patients at high risk of PONV undergoing lumbar spinal surgery." | 6.78 | Effect of ketamine as an adjunct to intravenous patient-controlled analgesia, in patients at high risk of postoperative nausea and vomiting undergoing lumbar spinal surgery. ( Kwak, YL; Park, SJ; Shim, JK; Song, JW; Song, Y; Yang, SY, 2013) |
| "The intensity of postoperative pain and analgesic requirement did not differ." | 6.70 | [Recovery from anaesthesia and incidence and intensity of postoperative nausea and vomiting following a total intravenous anaesthesia (TIVA) with S-(+)-ketamine/propofol compared to alfentanil/propofol]. ( Hering, W; Kessebohm, K; Kundt, HJ; Schmid, M; St Pierre, M, 2002) |
| "Ketamine also reduces postoperative nausea and vomiting." | 6.43 | Perioperative ketamine for acute postoperative pain. ( Bell, RF; Dahl, JB; Kalso, E; Moore, RA, 2006) |
| "The esketamine-based opioid-sparing anaesthetic protocol can shorten the postoperative first flatus time after benign laparoscopic surgery in gynaecology, and reduce the incidence of PONV." | 5.69 | Effects of intraoperative esketamine addition on gastrointestinal function after benign gynaecological laparoscopic surgery: a double-blind, randomized controlled study. ( Bao, S; Cao, X; Ma, W; Ma, Y; Ren, J; Zhang, L; Zhang, R, 2023) |
| "Subanaesthetic doses of esketamine can reduce postoperative pain in the PACU but delay the aesthetic recovery during the laparoscopic cholecystectomy, without affecting postoperative nausea and vomiting, and postoperative agitation." | 5.51 | Subanaesthetic dose of esketamine during induction delays anaesthesia recovery a randomized, double-blind clinical trial. ( Bao, F; He, J; Shi, Q; Xu, J; Zhang, C, 2022) |
| "After IRB approval and informed consent, 36 patients, aged 10-19 years, undergoing posterior correction surgery for adolescent idiopathic scoliosis, were randomly allocated into two groups: intra- and postoperative ketamine infusion at a rate of 2 μg/kg/min until 48 h after surgery (ketamine group, n = 17) or infusion of an equal volume of saline (placebo group, n = 19)." | 5.20 | Intra- and postoperative low-dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial. ( Hashiguchi, S; Ihara, N; Katori, N; Kosugi, S; Minoshima, R; Morisaki, H; Nishimura, D; Seki, H; Watanabe, K; Yamada, T, 2015) |
| "Ketamine and magnesium association reduces the post-operative morphine consumption after scoliosis surgery." | 5.19 | Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study. ( Abou Zeid, HA; Ghanem, IB; Jabbour, HJ; Jabbour, KB; Jawish, RJ; Naccache, NM; Rabbaa-Khabbaz, LG; Yazbeck, PH, 2014) |
| "To evaluate the postoperative analgesia after surgical site infiltration with bupivacaine or ketamine in children undergoing cleft palate surgery." | 5.17 | A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair. ( Bhardwaj, N; Jha, AK; Mahajan, JK; Sharma, RK; Yaddanapudi, S, 2013) |
| "Eighty-four children (aged two to seven years) undergoing elective strabismus surgery under sevoflurane anesthesia were randomly assigned to one of three groups (n = 28 each)." | 5.17 | Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. ( Chen, JY; Jia, JE; Li, WX; Liu, TJ; Qin, MJ, 2013) |
| "The ketofol 1:1 mixture is associated with longer mean seizure time than propofol, and shorter mean recovery times than ketamine, with better hemodynamic stability, without any important side effects in ECT anesthesia." | 5.16 | Ketofol in electroconvulsive therapy anesthesia: two stones for one bird. ( Aydoğan, H; Bilgiç, T; Karababa, F; Kucuk, A; Selek, S; Yalcin, S; Yuce, HH, 2012) |
| "Eighty children undertaking strabismus surgery were randomly divided into sevoflurane-N2O inhalation anaesthesia group with LMA (volatile group, n=40) and propofol-ketamine total intravenous anesthesia group (TIVA group, n=40)." | 5.12 | [Sevoflurane-N2O inhalation anaesthesia with laryngeal mask airway and propofol-ketamine intravenous anaesthesia in strabismus surgery]. ( Liu, Y; Zeng, QY, 2006) |
| "We tested the hypothesis that diprivan/ketamine (D/K) anesthesia would offer advantages compared to midazolam/ketamine (M/K) in patients undergoing minor gynecological surgery." | 5.12 | [Diprivan versus midazolam in combined anaesthesia with ketamin for minor gynecological surgery]. ( Partenov, P; Popov, I; Tablov, B; Tablov, V; Tsafarov, M, 2007) |
| " Ketamine was shown to increased postoperative nausea and vomiting." | 5.05 | Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review. ( Lin, H; Nguyen, BK; Pashkova, AA; Pinto, J; Quan, D; Stathakios, J; Svider, PF, 2020) |
| "To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia." | 4.98 | Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018) |
| "Peri-operative ketamine peritonsillar infiltration in children can reduce the incidence of postoperative nausea and vomiting (PONV), but its postoperative analgesic time is short." | 4.90 | Ketamine peritonsillar infiltration during tonsillectomy in pediatric patients: An updated meta-analysis. ( Chen, ZX; Ding, XB; Li, Q; Ren, H; Tong, Y; Wang, X, 2014) |
| "Safety and efficacy were assessed of different S(+)-ketamine doses combined with propofol administered as anesthesia to common pediatric congenital heart disease (CHD) patients undergoing cardiac interventional surgery to provide reference data as guidance for use in clinical settings." | 4.12 | Anaesthesia administered as S(+)-ketamine for cardiac intervention in children with common congenital heart disease. ( Guo, L; Li, H; Liu, W; Ma, J; Xu, F; Zhao, L, 2022) |
| " The incidence of postoperative nausea and vomiting was found to be significantly higher in the remifentanil group (P ≤ 0." | 3.83 | Comparison of ketamine-propofol and remifentanil in terms of hemodynamic variables and patient satisfaction during monitored anaesthesia care. ( Balci, C; Gaygusuz, EA; Oncul, S; Terzi, H; Yilmaz, M, 2016) |
| "Postoperative pain was managed by a rescue dose of 4 mg of IV morphine, with a minimum interval of 6 h between morphine doses if the numerical rating scale (NRS) score was ≥ 4." | 3.30 | Perioperative use of ketamine infusion versus dexmedetomidine infusion for analgesia in obese patients undergoing bariatric surgery: a double-blinded three-armed randomized controlled trial. ( Ali, BEEH; El-Shaer, AN; Elderh, MSH; Khaja, MAR; Khalil, BNM; Taeimah, MOA, 2023) |
| "All drugs reduced postoperative pain." | 3.01 | The efficacy and safety of peri-tonsillar administrated agents on pain treatment after pediatric tonsillectomy: A network meta-analysis. ( Basurrah, MA; Hwang, SH; Kim, DH; Kim, SW, 2023) |
| "Chronic postsurgical pain (CPSP) has become a common complication during the perioperative period." | 3.01 | Effects of Ketamine on Chronic Postsurgical Pain in Patients Undergoing Surgery: A Systematic Review and Meta-analysis. ( Cui, Y; Fan, J; Fu, Y; Han, R; Sun, W; Wang, J; Wang, L; Wu, Y; Yu, Y; Zhou, Y, 2023) |
| "The incidence of postoperative nausea and vomiting, as well as psychotomimetic adverse effects post-abdominal surgery were similar between the 2 groups, respectively." | 3.01 | Effect of S-ketamine on Postoperative Pain in Adults Post-Abdominal Surgery: A Systematic Review and Meta-analysis. ( Deng, Y; Li, T; Liang, Y; Xie, M, 2023) |
| "We observed that respiratory depression (19." | 2.82 | Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients. ( Babayıgıt, M; Baykal Tutal, Z; Derelı, N; Gulec, H; Horasanlı, E; Inceoz, H; Kurtay, A, 2016) |
| "A decreased incidence of postoperative nausea and vomiting (PONV) was observed at 2- and 6-hour visits in the intervention group." | 2.79 | Effects of intra-operative ketamine administration on postoperative catheter-related bladder discomfort: a double-blind clinical trial. ( Etezadi, F; Khajavi, M; Lajevardi, M; Najafi, A; Shariat Moharari, G; Shariat Moharari, R, 2014) |
| "patient-controlled analgesia (IV-PCA) on postoperative nausea and vomiting (PONV) in patients at high risk of PONV undergoing lumbar spinal surgery." | 2.78 | Effect of ketamine as an adjunct to intravenous patient-controlled analgesia, in patients at high risk of postoperative nausea and vomiting undergoing lumbar spinal surgery. ( Kwak, YL; Park, SJ; Shim, JK; Song, JW; Song, Y; Yang, SY, 2013) |
| "Management of postoperative pain and emergence agitation following adenotonsillectomy in pediatrics has been a major challenge for anesthesiologists." | 2.78 | Ketamine improves postoperative pain and emergence agitation following adenotonsillectomy in children. A randomized clinical trial. ( Amin, A; Eghbal, MH; Sahmeddini, MA; Taregh, S, 2013) |
| "Ketamine has been used as part of a multimodal analgesia regime in opioid abusers undergoing general anesthesia." | 2.78 | Opioid-sparing effect of preemptive bolus low-dose ketamine for moderate sedation in opioid abusers undergoing extracorporeal shock wave lithotripsy: a randomized clinical trial. ( Aghamohammadi, H; Elyassi, H; Gharaei, B; Jafari, A; Kamranmanesh, M; Poorzamani, M; Rostamian, B; Salimi, A, 2013) |
| " Important predictors found for postoperative pain on arrival to the recovery room are the group (P = 0." | 2.76 | Ketamine as an adjunct to fentanyl improves postoperative analgesia and hastens discharge in children following tonsillectomy - a prospective, double-blinded, randomized study. ( Chidambaran, V; Elshammaa, N; Housny, W; Michael, R; Thomas, J; Zhang, X, 2011) |
| "The incidence of postoperative pain was significantly lower in groups 1 [7 (36." | 2.76 | Intravenous and peritonsillar infiltration of ketamine for postoperative pain after adenotonsillectomy: a randomized placebo-controlled clinical trial. ( Dehghankhalili, M; Ghaffarpasand, F; Heiran, HR; Khademi, S; Motazedian, S; Yavari, MJ, 2011) |
| "Ketamine was associated with all reported nausea and vomiting incidents because propofol and midazolam are rarely associated with such events." | 2.73 | Retrospective outcomes evaluation of 100 parenteral moderate and deep sedations conducted in a general practice dental residency. ( Cruz-Gonzalez, W; Hakim, MI; Messieha, Z, 2008) |
| "ketamine was effective in preventing shivering developed during regional anaesthesia." | 2.73 | Control of shivering during regional anaesthesia: prophylactic ketamine and granisetron. ( Begec, Z; Ersoy, O; Gulhas, N; Sagir, O; Toprak, H; Yucel, A, 2007) |
| "In some patients, control of postoperative pain can be difficult with morphine alone." | 2.73 | The use of ketamine as rescue analgesia in the recovery room following morphine administration--a double-blind randomised controlled trial in postoperative patients. ( Angliss, M; Gillies, A; Lindholm, D; Orr, A, 2007) |
| "No patient had hallucinations." | 2.73 | Subanaesthetic ketamine spares postoperative morphine and controls pain better than standard morphine does alone in orthopaedic-oncological patients. ( Bickels, J; Chazan, S; Kollender, Y; Maruoani, N; Meller, I; Nirkin, A; Stocki, D; Weinbroum, AA, 2008) |
| "Ketamine decreases postoperative morphine consumption, but its optimal dosing and duration of administration remain unclear." | 2.73 | Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study. ( Beloucif, S; Dupont, H; Lorne, E; Montravers, P; Moubarak, M; Samarcq, D; Zakine, J, 2008) |
| "The ketamine group was administered a ketamine bolus and infusion during surgery." | 2.71 | Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery. ( Karaman, H; Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003) |
| "Treatment with ketamine and pethidine is effective in postoperative shivering." | 2.71 | Efficacy of prophylactic ketamine in preventing postoperative shivering. ( Akinci, SB; Aypar, U; Basgul, E; Dal, D; Honca, M; Kose, A, 2005) |
| " However, various dosing regimens when used alone or in combination have variable efficacy and side effect profile." | 2.71 | Comparative evaluation of midazolam and ketamine with midazolam alone as oral premedication. ( Chari, P; Ghai, B; Grandhe, RP; Kumar, A, 2005) |
| "Monitoring for pain, sedation, postoperative nausea/vomiting, dizziness, and pruritus was performed by anesthesiologists blinded to the study allocation." | 2.71 | Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine. ( Acharya, A; Kumar, P; Pan, AK; Rudra, A, 2005) |
| "The intensity of postoperative pain and analgesic requirement did not differ." | 2.70 | [Recovery from anaesthesia and incidence and intensity of postoperative nausea and vomiting following a total intravenous anaesthesia (TIVA) with S-(+)-ketamine/propofol compared to alfentanil/propofol]. ( Hering, W; Kessebohm, K; Kundt, HJ; Schmid, M; St Pierre, M, 2002) |
| " However, there was an increase in postoperative nausea and vomiting, psychomimetic side effects, and delay in discharge times with the largest ketamine dosage (Group 4)." | 2.69 | The use of a ketamine-propofol combination during monitored anesthesia care. ( Avramov, MN; Badrinath, S; Ivankovich, AD; Shadrick, M; Witt, TR, 2000) |
| "Secondary outcomes included postoperative pain score, duration of discharge time, and the adverse effects associated with the use of ketamine, namely postoperative nausea and vomiting, desaturation, and laryngospasm." | 2.61 | The effect of ketamine on emergence agitation in children: A systematic review and meta-analysis. ( Lai, YS; Ng, KT; Sarode, D; Teoh, WY; Wang, CY, 2019) |
| "Ketamine did not increase the prevalence of either postoperative nausea and vomiting or psychotomimetic complications." | 2.53 | Opioid-Sparing Effect of Ketamine in Children: A Meta-Analysis and Trial Sequential Analysis of Published Studies. ( Abdat, R; Brasher, C; Dahmani, S; Diallo, T; Hilly, J; Michelet, D; Skhiri, A, 2016) |
| "Ketamine was able to accomplish some preemptive analgesic effects of reducing postoperative morphine consumption and prolonging the time to first analgesic." | 2.50 | Preemptive analgesia effects of ketamine in patients undergoing surgery. A meta-analysis. ( Li, J; Yang, L; Zhang, C; Zhang, J; Zhang, Z; Zhao, D, 2014) |
| "In the case of postoperative nausea and vomiting, administration of dexamethasone, droperidol and 5-HT3-antagonists is recommended, preferably in combination." | 2.49 | ['Postoperative pain treatment' practice guideline revised]. ( Hollmann, MW; Houweling, PL; Molag, ML; van Boekel, RL; van Haelst, IM; Verbrugge, SJ, 2013) |
| "Ketamine also reduces postoperative nausea and vomiting." | 2.43 | Perioperative ketamine for acute postoperative pain. ( Bell, RF; Dahl, JB; Kalso, E; Moore, RA, 2006) |
| "Weighted mean difference (WMD) for postoperative pain intensity (0-10 cm visual analogue scale) was -0." | 2.43 | Ketamine and postoperative pain--a quantitative systematic review of randomised trials. ( Elia, N; Tramèr, MR, 2005) |
| "Even ketamine has an unpleasant taste." | 1.62 | Preanesthetic nebulized ketamine vs preanesthetic oral ketamine for sedation and postoperative pain management in children for elective surgery: A retrospective analysis for effectiveness and safety. ( Chen, C; Cheng, X; Fu, F; Lin, L, 2021) |
| "Nitrous oxide inhalation has also been found to enhance the level of sensory spinal block." | 1.40 | The effects of intrathecal and systemic adjuvants on subarachnoid block. ( Paraskeva, A; Staikou, C, 2014) |
| "Glycopyrrolate was associated with significantly more airway and respiratory adverse events (6." | 1.36 | Anticholinergics and ketamine sedation in children: a secondary analysis of atropine versus glycopyrrolate. ( Green, SM; Krauss, B; Roback, MG, 2010) |
| "To determine the incidence of postoperative nausea and vomiting (PONV) after oral and maxillofacial surgical procedures and to evaluate the rationale behind prophylactic antiemetic medications." | 1.35 | Prophylactic antiemetics in oral and maxillofacial surgery: a requiem? ( Alexander, M; Krishnan, B; Yuvraj, V, 2009) |
| " Intra- and postoperative adverse events, times to spontaneous awakening and discharge from the PACU were noted." | 1.35 | Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children. ( Dalal, PG; Seth, N; Somerville, N; Taylor, D, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 32 (42.67) | 29.6817 |
| 2010's | 31 (41.33) | 24.3611 |
| 2020's | 12 (16.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, C | 2 |
| He, J | 1 |
| Shi, Q | 1 |
| Bao, F | 1 |
| Xu, J | 1 |
| Liu, W | 1 |
| Xu, F | 1 |
| Guo, L | 1 |
| Li, H | 1 |
| Zhao, L | 1 |
| Ma, J | 1 |
| Thijssen, M | 1 |
| Timmerman, L | 1 |
| Koning, NJ | 1 |
| Rinia, M | 1 |
| van Dijk, JFM | 1 |
| Cheuk-Alam, J | 1 |
| Olthof, K | 1 |
| Rekker, S | 1 |
| Steegers, MAH | 1 |
| van Boekel, RLM | 1 |
| Kim, DH | 1 |
| Kim, SW | 1 |
| Basurrah, MA | 1 |
| Hwang, SH | 1 |
| Khalil, BNM | 1 |
| Elderh, MSH | 1 |
| Khaja, MAR | 1 |
| El-Shaer, AN | 1 |
| Ali, BEEH | 1 |
| Taeimah, MOA | 1 |
| Sun, W | 1 |
| Zhou, Y | 1 |
| Wang, J | 1 |
| Fu, Y | 1 |
| Fan, J | 1 |
| Cui, Y | 1 |
| Wu, Y | 1 |
| Wang, L | 1 |
| Yu, Y | 1 |
| Han, R | 1 |
| Ma, Y | 1 |
| Zhang, R | 1 |
| Cao, X | 1 |
| Zhang, L | 1 |
| Bao, S | 1 |
| Ren, J | 1 |
| Ma, W | 1 |
| Xie, M | 1 |
| Liang, Y | 1 |
| Deng, Y | 1 |
| Li, T | 1 |
| Chen, X | 1 |
| Zhu, Y | 1 |
| Peng, K | 1 |
| Wang, Q | 1 |
| Feng, C | 1 |
| Ng, KT | 1 |
| Sarode, D | 1 |
| Lai, YS | 1 |
| Teoh, WY | 1 |
| Wang, CY | 1 |
| Nguyen, BK | 1 |
| Stathakios, J | 1 |
| Quan, D | 1 |
| Pinto, J | 1 |
| Lin, H | 1 |
| Pashkova, AA | 1 |
| Svider, PF | 1 |
| Chen, C | 1 |
| Cheng, X | 1 |
| Lin, L | 1 |
| Fu, F | 1 |
| Gürcan, HS | 1 |
| Ülgey, A | 1 |
| Öz Gergin, Ö | 1 |
| Seçkin Pehlivan, S | 1 |
| Yıldız, K | 1 |
| Canpolat, DG | 1 |
| Yildirim, MD | 1 |
| Kutuk, N | 1 |
| Dogruel, F | 1 |
| Ocak, H | 1 |
| Aksu, R | 1 |
| Alkan, A | 1 |
| Schmitz, A | 1 |
| Weiss, M | 1 |
| Kellenberger, C | 1 |
| O'Gorman Tuura, R | 1 |
| Klaghofer, R | 1 |
| Scheer, I | 1 |
| Makki, M | 1 |
| Sabandal, C | 1 |
| Buehler, PK | 1 |
| Brinck, EC | 1 |
| Tiippana, E | 1 |
| Heesen, M | 1 |
| Bell, RF | 3 |
| Straube, S | 1 |
| Moore, RA | 3 |
| Kontinen, V | 1 |
| Jha, AK | 1 |
| Bhardwaj, N | 1 |
| Yaddanapudi, S | 1 |
| Sharma, RK | 1 |
| Mahajan, JK | 1 |
| Tekelioglu, UY | 1 |
| Apuhan, T | 1 |
| Akkaya, A | 1 |
| Demirhan, A | 1 |
| Yildiz, I | 1 |
| Simsek, T | 1 |
| Gok, U | 1 |
| Kocoglu, H | 1 |
| Shariat Moharari, R | 1 |
| Lajevardi, M | 1 |
| Khajavi, M | 1 |
| Najafi, A | 1 |
| Shariat Moharari, G | 1 |
| Etezadi, F | 1 |
| Abback, PS | 1 |
| Ben Sallah, T | 1 |
| Hilly, J | 2 |
| Skhiri, A | 2 |
| Silins, V | 1 |
| Brasher, C | 2 |
| François, M | 1 |
| Van Den Abeele, T | 1 |
| Wood, C | 1 |
| Nivoche, Y | 1 |
| Dahmani, S | 2 |
| Song, JW | 1 |
| Shim, JK | 1 |
| Song, Y | 1 |
| Yang, SY | 1 |
| Park, SJ | 1 |
| Kwak, YL | 1 |
| Staikou, C | 1 |
| Paraskeva, A | 1 |
| Eghbal, MH | 1 |
| Taregh, S | 1 |
| Amin, A | 1 |
| Sahmeddini, MA | 1 |
| Houweling, PL | 1 |
| Molag, ML | 1 |
| van Boekel, RL | 1 |
| Verbrugge, SJ | 1 |
| van Haelst, IM | 1 |
| Hollmann, MW | 1 |
| Ziemann-Gimmel, P | 1 |
| Goldfarb, AA | 1 |
| Koppman, J | 1 |
| Marema, RT | 1 |
| Jabbour, HJ | 1 |
| Naccache, NM | 1 |
| Jawish, RJ | 1 |
| Abou Zeid, HA | 1 |
| Jabbour, KB | 1 |
| Rabbaa-Khabbaz, LG | 1 |
| Ghanem, IB | 1 |
| Yazbeck, PH | 1 |
| Tong, Y | 1 |
| Ding, XB | 1 |
| Wang, X | 1 |
| Ren, H | 1 |
| Chen, ZX | 1 |
| Li, Q | 1 |
| Yang, L | 1 |
| Zhang, J | 1 |
| Zhang, Z | 1 |
| Zhao, D | 1 |
| Li, J | 1 |
| Minoshima, R | 1 |
| Kosugi, S | 1 |
| Nishimura, D | 1 |
| Ihara, N | 1 |
| Seki, H | 1 |
| Yamada, T | 1 |
| Watanabe, K | 1 |
| Katori, N | 1 |
| Hashiguchi, S | 1 |
| Morisaki, H | 1 |
| Dahl, JB | 2 |
| Kalso, EA | 1 |
| Baykal Tutal, Z | 1 |
| Gulec, H | 1 |
| Derelı, N | 1 |
| Babayıgıt, M | 1 |
| Kurtay, A | 1 |
| Inceoz, H | 1 |
| Horasanlı, E | 1 |
| Oncul, S | 1 |
| Gaygusuz, EA | 1 |
| Yilmaz, M | 1 |
| Terzi, H | 1 |
| Balci, C | 1 |
| Michelet, D | 1 |
| Abdat, R | 1 |
| Diallo, T | 1 |
| El Shobary, HM | 1 |
| Sonbul, ZM | 1 |
| Schricker, TP | 1 |
| Messieha, Z | 1 |
| Cruz-Gonzalez, W | 1 |
| Hakim, MI | 1 |
| Alexander, M | 1 |
| Krishnan, B | 1 |
| Yuvraj, V | 1 |
| Green, SM | 1 |
| Roback, MG | 1 |
| Krauss, B | 1 |
| Koruk, S | 1 |
| Mizrak, A | 1 |
| Gul, R | 1 |
| Kilic, E | 1 |
| Yendi, F | 1 |
| Oner, U | 1 |
| Elshammaa, N | 1 |
| Chidambaran, V | 1 |
| Housny, W | 1 |
| Thomas, J | 1 |
| Zhang, X | 1 |
| Michael, R | 1 |
| Khademi, S | 1 |
| Ghaffarpasand, F | 1 |
| Heiran, HR | 1 |
| Yavari, MJ | 1 |
| Motazedian, S | 1 |
| Dehghankhalili, M | 1 |
| Colque, A | 1 |
| Eisemann, ML | 1 |
| Safavi, M | 1 |
| Honarmand, A | 1 |
| Habibabady, MR | 1 |
| Baraty, S | 1 |
| Aghadavoudi, O | 1 |
| Yalcin, S | 1 |
| Aydoğan, H | 1 |
| Selek, S | 1 |
| Kucuk, A | 1 |
| Yuce, HH | 1 |
| Karababa, F | 1 |
| Bilgiç, T | 1 |
| Lonjaret, L | 1 |
| Bataille, B | 1 |
| Gris, C | 1 |
| Fourcade, O | 1 |
| Minville, V | 1 |
| Gharaei, B | 1 |
| Jafari, A | 1 |
| Aghamohammadi, H | 1 |
| Kamranmanesh, M | 1 |
| Poorzamani, M | 1 |
| Elyassi, H | 1 |
| Rostamian, B | 1 |
| Salimi, A | 1 |
| Chen, JY | 1 |
| Jia, JE | 1 |
| Liu, TJ | 1 |
| Qin, MJ | 1 |
| Li, WX | 1 |
| St Pierre, M | 1 |
| Kessebohm, K | 1 |
| Schmid, M | 1 |
| Kundt, HJ | 1 |
| Hering, W | 1 |
| Roelofse, J | 1 |
| O'Flaherty, JE | 1 |
| Lin, CX | 1 |
| Kararmaz, A | 1 |
| Kaya, S | 1 |
| Karaman, H | 1 |
| Turhanoglu, S | 1 |
| Ozyilmaz, MA | 1 |
| Sarti, A | 1 |
| Busoni, P | 1 |
| Dell'Oste, C | 1 |
| Bussolin, L | 1 |
| Treston, G | 1 |
| Subramaniam, K | 1 |
| Subramaniam, B | 1 |
| Steinbrook, RA | 1 |
| Elia, N | 1 |
| Tramèr, MR | 1 |
| Adam, F | 1 |
| Chauvin, M | 2 |
| Du Manoir, B | 1 |
| Langlois, M | 1 |
| Sessler, DI | 2 |
| Fletcher, D | 1 |
| Almenrader, N | 1 |
| Passariello, M | 1 |
| D'Amico, G | 1 |
| Haiberger, R | 1 |
| Pietropaoli, P | 1 |
| Dalsasso, M | 1 |
| Tresin, P | 1 |
| Innocente, F | 1 |
| Veronese, S | 1 |
| Ori, C | 1 |
| Dal, D | 1 |
| Kose, A | 1 |
| Honca, M | 1 |
| Akinci, SB | 1 |
| Basgul, E | 1 |
| Aypar, U | 1 |
| Ghai, B | 1 |
| Grandhe, RP | 1 |
| Kumar, A | 1 |
| Chari, P | 1 |
| Kumar, P | 1 |
| Rudra, A | 1 |
| Pan, AK | 1 |
| Acharya, A | 1 |
| Sen, S | 1 |
| Ozmert, G | 1 |
| Aydin, ON | 1 |
| Baran, N | 1 |
| Caliskan, E | 1 |
| Kalso, E | 1 |
| Liu, Y | 1 |
| Zeng, QY | 1 |
| Sagir, O | 1 |
| Gulhas, N | 1 |
| Toprak, H | 1 |
| Yucel, A | 1 |
| Begec, Z | 1 |
| Ersoy, O | 1 |
| Erk, G | 1 |
| Ornek, D | 1 |
| Dönmez, NF | 1 |
| Taşpinar, V | 1 |
| Gillies, A | 1 |
| Lindholm, D | 1 |
| Angliss, M | 1 |
| Orr, A | 1 |
| Nafiu, OO | 1 |
| Kolawole, IK | 1 |
| Salam, RA | 1 |
| Elegbe, EO | 1 |
| Tablov, V | 1 |
| Tsafarov, M | 1 |
| Tablov, B | 1 |
| Popov, I | 1 |
| Partenov, P | 1 |
| Dalal, PG | 1 |
| Taylor, D | 1 |
| Somerville, N | 1 |
| Seth, N | 1 |
| Kollender, Y | 1 |
| Bickels, J | 1 |
| Stocki, D | 1 |
| Maruoani, N | 1 |
| Chazan, S | 1 |
| Nirkin, A | 1 |
| Meller, I | 1 |
| Weinbroum, AA | 1 |
| Zakine, J | 1 |
| Samarcq, D | 1 |
| Lorne, E | 1 |
| Moubarak, M | 1 |
| Montravers, P | 1 |
| Beloucif, S | 1 |
| Dupont, H | 1 |
| McGlone, R | 1 |
| Carley, S | 1 |
| Badrinath, S | 1 |
| Avramov, MN | 1 |
| Shadrick, M | 1 |
| Witt, TR | 1 |
| Ivankovich, AD | 1 |
| Terada, Y | 1 |
| Furuya, A | 1 |
| Ishiyama, T | 1 |
| Matsukawa, T | 1 |
| Kumazawa, T | 1 |
| Guignard, B | 1 |
| Coste, C | 1 |
| Costes, H | 1 |
| Lebrault, C | 1 |
| Morris, W | 1 |
| Simonnet, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of The Effectiveness of Intranasal Dexmedetomidine Sedation at Dose of 2 mcg/kg and 4 mcg/kg in Children Undergoing MRI at Cipto Mangunkusumo Hospital[NCT05091151] | 94 participants (Actual) | Interventional | 2019-02-01 | Completed | |||
| The Effect of Low-dose of S-ketamine Combined With Sufentanil for Postoperative Patient-controlled Intravenous Analgesia in Patients Following Cesarean Section[NCT05299866] | Phase 4 | 216 participants (Anticipated) | Interventional | 2022-04-12 | Recruiting | ||
| Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial[NCT04964219] | Phase 4 | 164 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Patient-controlled Analgesia After Scoliosis Correction Surgery: a Randomized, Double-blind, Placebo-controlled Trial[NCT04791059] | Phase 4 | 200 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| Observational Study of the Efficacy of Ketamine for Rescue Analgesia in the Post Anesthesia Recovery Room[NCT04701008] | 143 participants (Actual) | Observational | 2020-09-01 | Completed | |||
| The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283] | Phase 4 | 1,544 participants (Anticipated) | Interventional | 2021-04-12 | Enrolling by invitation | ||
| Effect of Tramadol on Postoperative Sore Throat in Thyroid Surgery Under General Anesthesia With Endotracheal Intubation: A Randomized Controlled Trial[NCT04991493] | Phase 4 | 168 participants (Anticipated) | Interventional | 2021-09-10 | Recruiting | ||
| The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031] | Phase 4 | 54 participants (Actual) | Interventional | 2016-03-17 | Completed | ||
| Recovery Parameters and Nociception Levels in Opioid-free Versus Opioid Based Anesthesia for Thyroidectomy[NCT05243940] | 60 participants (Anticipated) | Interventional | 2022-03-07 | Recruiting | |||
| Opioid Free Versus Opioid Balanced Anesthesia in Middle Ear Surgery.[NCT03809949] | Phase 4 | 60 participants (Actual) | Interventional | 2019-01-16 | Completed | ||
| Role of Scheduled Intravenous Acetaminophen for Postoperative Pain Management in an Enhanced Recovery After Surgery (ERAS) Population: A Prospective, Randomized, Double-Blind and Placebo-Controlled Clinical Trial[NCT03198871] | Phase 4 | 180 participants (Actual) | Interventional | 2018-05-24 | Completed | ||
| Rates and Severity of Postoperative and Post-discharge Nausea and Vomiting of Patients Receiving Sugammadex Versus Neostigmine and Glycopyrrolate for Neuromuscular Block Reversal in Patients Receiving Gastric Bypass Bariatric Surgery[NCT03432845] | 0 participants (Actual) | Observational | 2018-06-01 | Withdrawn (stopped due to PI left institution) | |||
| Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting (PONV) in Bariatric Surgery[NCT01449708] | Phase 4 | 124 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| The Comparison of Analgesia Methods Used for Spinal Surgery[NCT04603638] | 82 participants (Anticipated) | Interventional | 2020-03-04 | Recruiting | |||
| The Effect of a Regimen of Opioid Sparing Anesthesia on Postoperative Recovery[NCT05594407] | 60 participants (Anticipated) | Interventional | 2022-08-01 | Recruiting | |||
| Comparison of Effect of Peritonsillar Infiltration of Ketamine and Tramadol on Pediatric Posttonsillectomy Pain: A Double-blinded Randomized Placebo-controlled Clinical Trial[NCT03067103] | Phase 4 | 108 participants (Anticipated) | Interventional | 2017-07-01 | Not yet recruiting | ||
| Postoperative Analgesic Efficacy of the Pulmonary Recruitment Maneuver Compared to Intraperitoneal Hydrocortisone in Laparoscopic Gynecological Surgery[NCT03845608] | Phase 4 | 45 participants (Anticipated) | Interventional | 2019-03-31 | Not yet recruiting | ||
| Turgut Ozal Medical Center Department of Anesthesiology and Reanimation[NCT02267980] | Phase 4 | 60 participants (Anticipated) | Interventional | 2014-07-31 | Recruiting | ||
| Effect of Intravenous Nalbuphine on Emergence Agitation in Children Undergoing Repair of Rupture Globe[NCT03470077] | Phase 2 | 80 participants (Actual) | Interventional | 2019-07-31 | Completed | ||
| Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?[NCT00486902] | 188 participants (Actual) | Interventional | 2006-07-31 | Completed | |||
| PCA Ketamine-Morphine Versus PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.[NCT06010056] | Phase 4 | 60 participants (Actual) | Interventional | 2018-04-05 | Completed | ||
| A Prospective, Randomized, Double-Blind, Controlled Trial Evaluating the Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis[NCT02651324] | Phase 4 | 50 participants (Anticipated) | Interventional | 2013-05-31 | Active, not recruiting | ||
| Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417] | Phase 2 | 120 participants (Anticipated) | Interventional | 2022-05-01 | Not yet recruiting | ||
| Study of the Efficacity of the Systemic Ketamine for the Improvement of Post-Operative Analgesia After ORL Carcinological Surgery at the Alcohol-Dependent Patient.[NCT00329394] | Phase 3 | 56 participants (Anticipated) | Interventional | 2006-04-30 | Suspended | ||
| Intranasal Ketamine Versus Subcutaneous Ketamine for Treatment of Post Traumatic Acute Pain in the Emergency Department[NCT05229055] | Phase 2/Phase 3 | 1,000 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | ||
| Spreading Depolarization and Ketamine Suppression[NCT02501941] | Phase 1 | 10 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| Lidocaine and Ketamine in Abdominal Surgery[NCT04084548] | Phase 3 | 420 participants (Anticipated) | Interventional | 2019-10-15 | Recruiting | ||
| Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty: Optimum Dose to Reduce Morphine Consumption[NCT04085588] | 75 participants (Actual) | Observational | 2019-04-15 | Completed | |||
| Comparing the Effectiveness of Low-dose Ketamine With Morphine to Treat Pain in Patients With Long Bone Fractures[NCT02430818] | 13 participants (Actual) | Interventional | 2015-04-30 | Terminated (stopped due to were not able to enroll patients to a satisfactory level) | |||
| A Prospective, Randomized, Single Blinded Comparison of Intraoperative Ketamine Infusion Versus Placebo in Patients Having Spinal Fusion[NCT02424591] | Phase 4 | 46 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 33.7 |
| Study Arm | 21.2 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 63.5 |
| Study Arm | 43.5 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 38.9 |
| Study Arm | 22.9 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 2 |
| Study Arm | 3 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 3 |
| Study Arm | 3 |
Number of patients who score greater than a 4 on the 0-8 point ICDSC scale to assess delirium scores. 8 separate levels of signs for delirium assessed (1. altered level of consciousness, 2. inattention, 3. disorientation, 4. hallucination, delusion, or psychosis, 5. psychomotor agitation or retardation, 6. inappropriate speech or mood, 7. sleep-wake cycle disturbance, 8. symptom fluctuation), with 0 points awarded when patient does not exhibit above signs of delirium and 1 point awarded per confirmed sign of delirium. Score then totaled, 0 = normal, 1-3 = subsyndromal delirium, 4-8 = delirium. (NCT03198871)
Timeframe: The delirium scores will first be measured every 12 hours for 72 hours after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 0 |
| Sodium Chloride 0.9%, Intravenous | 0 |
If the patient is readmitted to the hospital after being fully discharged, the event will be recorded. (NCT03198871)
Timeframe: From the time of consent until 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 9 |
| Sodium Chloride 0.9%, Intravenous | 10 |
Number of patients with unsatisfactory pain relief defined as average numeric rating scale (NRS) more than 5 will be compared between the two groups. This may include patients using IVPCA for pain relief during the first 48 hours postoperative. (NCT03198871)
Timeframe: PACU admission every thirty minutes until discharge to the floor and thereafter every four hours for first 24-hour, then every six hours until 48 hours and then every twelve hours until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 33 |
| Sodium Chloride 0.9%, Intravenous | 42 |
The time it takes for the patient to successfully ambulate post-surgery will be measured. (NCT03198871)
Timeframe: From date of PACU admission until the date of first documented ambulation, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 18.82 |
| Sodium Chloride 0.9%, Intravenous | 17.38 |
The time it takes for the first bowel movement postoperatively will be measured. (NCT03198871)
Timeframe: From time patient left operating room until the time of first documented bowel movement, assessed up to hospital discharge
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 46.30 |
| Sodium Chloride 0.9%, Intravenous | 64.66 |
The time it takes for the patient to be fully discharged from the hospital post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of hospital discharge or 30 days postoperatively, whichever comes first
| Intervention | days (Median) |
|---|---|
| Acetaminophen Injectable Product | 4.08 |
| Sodium Chloride 0.9%, Intravenous | 4.94 |
The time it takes for the patient to ingest orally post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of first documented oral intake, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 12.15 |
| Sodium Chloride 0.9%, Intravenous | 9.40 |
The time from PACU admission to PACU discharge to the floor will be measured. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge, assessed up to 24 hours postoperatively
| Intervention | minutes (Median) |
|---|---|
| Acetaminophen Injectable Product | 129.00 |
| Sodium Chloride 0.9%, Intravenous | 152.50 |
Overall patient satisfaction as well as satisfaction relating to pain management and cost analyses will be measured. These will be measured with a numerical rating scale (NRS) with 0- being worst satisfaction and 10 - best satisfaction. (NCT03198871)
Timeframe: These measurements will be taken at time of discharge up to 30 days, whichever comes first
| Intervention | score on a scale (Median) | |
|---|---|---|
| Patient satisfaction score, overall | Patient Satisfaction score, pain management | |
| Acetaminophen Injectable Product | 10 | 10 |
| Sodium Chloride 0.9%, Intravenous | 10 | 10 |
Frequency of emesis and rescue antiemetic requirement will be documented (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Emesis incidence 0-72 hours | Antiemetic use | |
| Acetaminophen Injectable Product | 12 | 31 |
| Sodium Chloride 0.9%, Intravenous | 14 | 45 |
Nausea will be evaluated by nausea score from 0 to 10, with 0 equaling no nausea and 10 equaling the worst nausea imaginable. (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Nausea score POD 1 (am visit) | Nausea score POD 1 (pm visit) | Nausea score POD 2 (am visit) | Nausea score POD 2 (pm visit) | Nausea score POD 3 (am visit) | Nausea score POD 3 (pm visit) | |
| Acetaminophen Injectable Product | 1.13 | 0.49 | 0.71 | 0.55 | 0.32 | 0.56 |
| Sodium Chloride 0.9%, Intravenous | 0.60 | 0.92 | 0.75 | 0.69 | 0.66 | 0.78 |
Survey to assess patient's overall health (via a combination of mental and physical health assessment) at 30 days post-discharge. Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations). The United States population average PCS-12 and MCS-12 are both 50 points. The United States population standard deviation is 10 points. So each 10 increment of 10 points above or below 50, corresponds to one standard deviation away from the average (NCT03198871)
Timeframe: These measurements will take place at 30-days post hospital discharge
| Intervention | Z-scores (difference compared to the pop (Median) | |
|---|---|---|
| SF 12 Physical score | SF 12 Mental score | |
| Acetaminophen Injectable Product | 38.72 | 54.02 |
| Sodium Chloride 0.9%, Intravenous | 38.07 | 52.08 |
Rescue analgesia will be given according to institutional pain management protocol. Unit of Measure recorded as OME (Oral Morphine Equivalent) consumption in mg. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge and 72-hours postoperatively, whichever comes first
| Intervention | mg (Median) | ||||
|---|---|---|---|---|---|
| 0-24 hours | 24-48 hours | 48-72 hours | 0-48 hours | 0-72 hours | |
| Acetaminophen Injectable Product | 27.4 | 31.3 | 30 | 74 | 105.00 |
| Sodium Chloride 0.9%, Intravenous | 36 | 45 | 37.5 | 88.8 | 127.1 |
(NCT01449708)
Timeframe: 24hours
| Intervention | participants (Number) |
|---|---|
| Classic/Balanced Anesthesia | 26 |
| TIVA | 17 |
Postoperative Nausea and Vomiting (NCT01449708)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Classic / Balanced Anesthesia | 22 |
| TIVA | 12 |
(NCT01449708)
Timeframe: 24 hours
| Intervention | percentage of participants (Number) | ||||
|---|---|---|---|---|---|
| Sleeve Gastrectomy | Gastric Bypass (LRYGB) | Gastric Band | revision LRYGB | Conversion to LRYGB | |
| All Study Participants | 58.6 | 19.4 | 0 | 23.1 | 0 |
Cumulative hydrocodone/acetaminophen for supplemental analgesia to treat breakthrough pain for 72 hours following cesarean delivery (NCT00486902)
Timeframe: 72 hours
| Intervention | tablets (Median) |
|---|---|
| Ketamine | 10 |
| Placebo | 9 |
Number of subject reporting disturbing dreams at 72 hours post cesarean delivery (NCT00486902)
Timeframe: 72 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 0 |
| Placebo | 0 |
Request for oral hydrocodone/acetaminophen for pain not controlled by around the clock non-steroidal antiflammatory drugs in the first 24 hours following cesarean delivery. (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 64 |
| Placebo | 66 |
Numeric rating for pain score (0 to 10) reported at 2 weeks following cesarean delivery. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 2 weeks
| Intervention | Scores on a scale (Median) |
|---|---|
| Ketamine | 2 |
| Placebo | 2.6 |
Number of subjects reporting nausea in first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 27 |
| Placebo | 30 |
Number of subjects that vomited in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 13 |
| Placebo | 13 |
Number of subjects with pruritus in the first 24 hours following cesarean delivery (NCT00486902)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Ketamine | 12 |
| Placebo | 19 |
Numeric rating of pain scores (NRS) scale (0 to 10) at time of supplemental analgesia request. Zero is no pain and 10 is worst pain imaginable. (NCT00486902)
Timeframe: 24 hours
| Intervention | Scores on a scale (Median) |
|---|---|
| Ketamine | 3 |
| Placebo | 4 |
We will monitor for adverse effects and record for changes in vital signs including nausea and vomiting, hypotension, respiratory depression, laryngospasm, and emotional and psychological effects (emergence reactions). (NCT02430818)
Timeframe: 60 minutes
| Intervention | participants (Number) |
|---|---|
| Ketamine | 1 |
| Morphine | 1 |
Study outcomes involve change in participants' pain as measured by a visual analog scale. The scale is a 10 inch line from 0 to 10 inches with 10 being the most pain and 0 being no pain. There are no units on the scale; it is just a straight line from no pain (0) to the worst pain (10). We assessed at o, 15, and 60 minutes but only scored the VAS at 60 minutes. (NCT02430818)
Timeframe: At 0 minutes and 60 minutes
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 4 |
| Morphine | 4 |
Patients will be assessed to determine whether the participant would consider using the drug given to them for pain relief in the future. It was measured on a likert scale from 1-5 with 1 being did not like and would not use the drug again to 5 being like and would definitely receive the medication again. There are no units. The numbers below are the total number of patients that completed this answer. This was only asked on patients that received medication as if they did not receive medication the answer would not make sense. The median value is the likert value on a scale of 1-5 with the standard deviation. (NCT02430818)
Timeframe: 60 minutes
| Intervention | units on a scale (Median) |
|---|---|
| Ketamine | 4 |
| Morphine | 4 |
"Beck's Depression Inventory (BDI) is a 21-item, self-report rating inventory that measures attitudes and symptoms of depression. Each sentence has a rating from 0 to 3 and the sentences go from mild to fairly severe descriptions of moods. The numbers are tabulated, the lowest possible score is 0 and the highest is 63.~A score of 1-10 indicates normal ups and downs. 11-16 indicates a mild mood disturbance; 17-20, borderline clinical depression; 21-30, moderate depression; 31-40, severe depression; over 40, extreme depression" (NCT02424591)
Timeframe: Post-op Day 3
| Intervention | points (Median) |
|---|---|
| Ketamine | 8 |
| Placebo | 9 |
"McGill Short Form measures pain in different ways. The first part of the form lists 15 adjectives for pain, for which the answers can be none (0), Mild (1), Moderate (2) and Severe (3). Descriptors 1-11 represent the sensory dimension of pain experience and 12-15 represent the affective dimension. A score of 0 is good, and a score of 45 indicates extreme pain. The lower the score the less pain a subject feels (better), as the scores go up, so do the pain levels (worse).~PPI (Present Pain Intensity) asks patients to measure pain from 0 (no pain) to 5 (excruciating). Again, a lower score is ideal." (NCT02424591)
Timeframe: Post-op Day 3
| Intervention | points (Median) |
|---|---|
| Ketamine | 11 |
| Placebo | 10.5 |
Quality of Recovery 15 questions questionnaires that ask, on a scale of 0-10, with 0 always being bad and 10 always being best, how the patient is recovering. The total number is reviewed, so the highest total score possible is 150 and the lowest is 0. (NCT02424591)
Timeframe: Post-op Day 3
| Intervention | points (Median) |
|---|---|
| Ketamine | 95 |
| Placebo | 101 |
16 reviews available for ketamine and Emesis, Postoperative
| Article | Year |
|---|---|
The efficacy and safety of peri-tonsillar administrated agents on pain treatment after pediatric tonsillectomy: A network meta-analysis.
Topics: Analgesics; Analgesics, Opioid; Bupivacaine; Child; Dexamethasone; Double-Blind Method; Humans; Keta | 2023 |
Effects of Ketamine on Chronic Postsurgical Pain in Patients Undergoing Surgery: A Systematic Review and Meta-analysis.
Topics: Analgesics, Opioid; Chronic Pain; Humans; Ketamine; Pain, Postoperative; Postoperative Nausea and Vo | 2023 |
Effect of S-ketamine on Postoperative Pain in Adults Post-Abdominal Surgery: A Systematic Review and Meta-analysis.
Topics: Abdomen; Adult; Analgesics, Opioid; Humans; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2023 |
The effect of ketamine on emergence agitation in children: A systematic review and meta-analysis.
Topics: Adolescent; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, | 2019 |
Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review.
Topics: Acetaminophen; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Bas | 2020 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
['Postoperative pain treatment' practice guideline revised].
Topics: Adult; Amines; Analgesia, Epidural; Child; Cyclohexanecarboxylic Acids; Dexamethasone; Gabapentin; g | 2013 |
Ketamine peritonsillar infiltration during tonsillectomy in pediatric patients: An updated meta-analysis.
Topics: Analgesics; Child; Child, Preschool; Humans; Incidence; Ketamine; Pain Measurement; Pain, Postoperat | 2014 |
Preemptive analgesia effects of ketamine in patients undergoing surgery. A meta-analysis.
Topics: Analgesics; Analgesics, Opioid; Humans; Ketamine; Morphine; Operative Time; Pain Measurement; Pain, | 2014 |
WITHDRAWN: Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2015 |
Opioid-Sparing Effect of Ketamine in Children: A Meta-Analysis and Trial Sequential Analysis of Published Studies.
Topics: Analgesics, Opioid; Child; Humans; Ketamine; Pain, Postoperative; Postoperative Nausea and Vomiting | 2016 |
Overview of pharmacological aspects of sedation--Part I.
Topics: Analgesics; Anesthesia, Dental; Child; Chloral Hydrate; Conscious Sedation; Dental Anxiety; Humans; | 2000 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review.
Topics: Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissocia | 2004 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Ketamine and postoperative pain--a quantitative systematic review of randomised trials.
Topics: Adult; Age Factors; Analgesics; Child; Drug Administration Routes; Hallucinations; Humans; Ketamine; | 2005 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Perioperative ketamine for acute postoperative pain.
Topics: Analgesics; Humans; Infusions, Intravenous; Ketamine; Pain, Postoperative; Postoperative Nausea and | 2006 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 3: Does the time of fasting affect complication rates during ketamine sedation?
Topics: Child, Preschool; Conscious Sedation; Emergency Service, Hospital; Evidence-Based Medicine; Facial I | 2008 |
47 trials available for ketamine and Emesis, Postoperative
| Article | Year |
|---|---|
Subanaesthetic dose of esketamine during induction delays anaesthesia recovery a randomized, double-blind clinical trial.
Topics: Anesthesia, General; Double-Blind Method; Humans; Ketamine; Pain, Postoperative; Postoperative Nause | 2022 |
Perioperative use of ketamine infusion versus dexmedetomidine infusion for analgesia in obese patients undergoing bariatric surgery: a double-blinded three-armed randomized controlled trial.
Topics: Analgesia; Analgesics, Opioid; Bariatric Surgery; Dexmedetomidine; Double-Blind Method; Fentanyl; Hu | 2023 |
Effects of intraoperative esketamine addition on gastrointestinal function after benign gynaecological laparoscopic surgery: a double-blind, randomized controlled study.
Topics: Analgesics, Opioid; Double-Blind Method; Female; Flatulence; Gynecologic Surgical Procedures; Humans | 2023 |
Effect of S-ketamine on the intraoperative Surgical Pleth Index in patients undergoing video-assisted thoracoscopic surgery: a single-center randomized controlled clinical trial.
Topics: Analgesia; Analgesics, Opioid; Humans; Ketamine; Postoperative Nausea and Vomiting; Thoracic Surgery | 2023 |
Investigation of the effects of propofol/ketamine versus propofol/fentanyl on nausea- vomiting administered for sedation in children undergoing magnetic resonance imaging: a prospective randomized double-blinded study
Topics: Child; Child, Preschool; Conscious Sedation; Double-Blind Method; Drug Combinations; Female; Fentany | 2021 |
Comparison of ketamine-propofol and ketamine-dexmedetomidine combinations in children for sedation during tooth extraction.
Topics: Anesthetics, Dissociative; Anxiety; Child; Child, Preschool; Deep Sedation; Dexmedetomidine; Female; | 2017 |
Sedation for magnetic resonance imaging using propofol with or without ketamine at induction in pediatrics-A prospective randomized double-blinded study.
Topics: Anesthesia Recovery Period; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; | 2018 |
A randomized study of surgical site infiltration with bupivacaine or ketamine for pain relief in children following cleft palate repair.
Topics: Anesthesia, Local; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Child Behavior | 2013 |
Comparison of topical tramadol and ketamine in pain treatment after tonsillectomy.
Topics: Administration, Topical; Analgesics; Analgesics, Opioid; Child; Child, Preschool; Data Interpretatio | 2013 |
Effects of intra-operative ketamine administration on postoperative catheter-related bladder discomfort: a double-blind clinical trial.
Topics: Adult; Analgesics; Double-Blind Method; Female; Humans; Incidence; Intraoperative Care; Ketamine; Ma | 2014 |
Effect of ketamine as an adjunct to intravenous patient-controlled analgesia, in patients at high risk of postoperative nausea and vomiting undergoing lumbar spinal surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Admin | 2013 |
Ketamine improves postoperative pain and emergence agitation following adenotonsillectomy in children. A randomized clinical trial.
Topics: Adenoidectomy; Adolescent; Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Child; C | 2013 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Opioid-free total intravenous anaesthesia reduces postoperative nausea and vomiting in bariatric surgery beyond triple prophylaxis.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Antiemetics; Bariatric | 2014 |
Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics; Child; Double-Blind Method; Drug Therapy, Com | 2014 |
Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics; Child; Double-Blind Method; Drug Therapy, Com | 2014 |
Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics; Child; Double-Blind Method; Drug Therapy, Com | 2014 |
Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics; Child; Double-Blind Method; Drug Therapy, Com | 2014 |
Intra- and postoperative low-dose ketamine for adolescent idiopathic scoliosis surgery: a randomized controlled trial.
Topics: Adolescent; Child; Female; Humans; Ketamine; Male; Morphine; Pain, Postoperative; Postoperative Naus | 2015 |
Propofol-ketamine combination: a choice with less complications and better hemodynamic stability compared to propofol? On a prospective study in a group of colonoscopy patients.
Topics: Anesthetics, Combined; Colonoscopy; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; H | 2016 |
Epidural ketamine for postoperative analgesia in the elderly.
Topics: Abdomen; Aged; Analgesia, Epidural; Analgesics; Anesthetics, Local; Bupivacaine; Double-Blind Method | 2008 |
Retrospective outcomes evaluation of 100 parenteral moderate and deep sedations conducted in a general practice dental residency.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Dissociative; Anesthetics, Intravenous; Antiemet | 2008 |
Dexmedetomidine-ketamine and midazolam-ketamine combinations for sedation in pediatric patients undergoing extracorporeal shock wave lithotripsy: a randomized prospective study.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Dissociative; Child; Child, Preschool; Consciou | 2010 |
Ketamine as an adjunct to fentanyl improves postoperative analgesia and hastens discharge in children following tonsillectomy - a prospective, double-blinded, randomized study.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous | 2011 |
Intravenous and peritonsillar infiltration of ketamine for postoperative pain after adenotonsillectomy: a randomized placebo-controlled clinical trial.
Topics: Adenoidectomy; Adolescent; Analysis of Variance; Anesthetics, Dissociative; Antiemetics; Anxiety; Ch | 2011 |
Assessing intravenous ketamine and intravenous dexamethasone separately and in combination for early oral intake, vomiting and postoperative pain relief in children following tonsillectomy.
Topics: Analgesics; Antiemetics; Child; Child, Preschool; Dexamethasone; Eating; Female; Humans; Injections, | 2012 |
Ketofol in electroconvulsive therapy anesthesia: two stones for one bird.
Topics: Adult; Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Intravenous; | 2012 |
Opioid-sparing effect of preemptive bolus low-dose ketamine for moderate sedation in opioid abusers undergoing extracorporeal shock wave lithotripsy: a randomized clinical trial.
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Con | 2013 |
Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children.
Topics: Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Inhalation; Child; Child, Presch | 2013 |
[Recovery from anaesthesia and incidence and intensity of postoperative nausea and vomiting following a total intravenous anaesthesia (TIVA) with S-(+)-ketamine/propofol compared to alfentanil/propofol].
Topics: Adolescent; Aged; Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Diss | 2002 |
Does ketamine or magnesium affect posttonsillectomy pain in children?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child | 2003 |
Intraoperative intravenous ketamine in combination with epidural analgesia: postoperative analgesia after renal surgery.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Dissociative; Anes | 2003 |
Incidence of vomiting in susceptible children under regional analgesia with two different anaesthetic techniques.
Topics: Anesthesia, Conduction; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous | 2004 |
Prolonged pre-procedure fasting time is unnecessary when using titrated intravenous ketamine for paediatric procedural sedation.
Topics: Age Distribution; Anesthesia, Intravenous; Anesthetics, Dissociative; Child; Child, Preschool; Fasti | 2004 |
Small-dose ketamine infusion improves postoperative analgesia and rehabilitation after total knee arthroplasty.
Topics: Aged; Analgesics, Opioid; Anesthetics, Dissociative; Arthroplasty, Replacement, Knee; Double-Blind M | 2005 |
Caudal additives for postoperative pain management in children: S(+)-ketamine and neostigmine.
Topics: Analgesics; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation; | 2005 |
Low-dose ketamine with clonidine and midazolam for adult day care surgery.
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesth | 2005 |
Efficacy of prophylactic ketamine in preventing postoperative shivering.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthetics, Dissociative; Chi-Square Distribution; Do | 2005 |
Comparative evaluation of midazolam and ketamine with midazolam alone as oral premedication.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia Recovery Period; Anesthetics, Dissociative; | 2005 |
Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine.
Topics: Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Intravenous; Anest | 2005 |
The persisting analgesic effect of low-dose intravenous ketamine after spinal anaesthesia for caesarean section.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Dissociative | 2005 |
[Sevoflurane-N2O inhalation anaesthesia with laryngeal mask airway and propofol-ketamine intravenous anaesthesia in strabismus surgery].
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Child; Child, Preschool; China; Female; Humans; Ke | 2006 |
Control of shivering during regional anaesthesia: prophylactic ketamine and granisetron.
Topics: Adult; Anesthesia, Spinal; Anesthetics, Dissociative; Antiemetics; Body Temperature; Double-Blind Me | 2007 |
The use of ketamine or ketamine-midazolam for adenotonsillectomy.
Topics: Adenoidectomy; Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Atropin | 2007 |
The use of ketamine as rescue analgesia in the recovery room following morphine administration--a double-blind randomised controlled trial in postoperative patients.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Humans; Ketamine; Male; Midd | 2007 |
Comparison of caudal ketamine with or without bupivacaine in pediatric subumbilical surgery.
Topics: Abdomen; Anesthesia, Caudal; Anesthetics, Dissociative; Anesthetics, Local; Bupivacaine; Child; Chil | 2007 |
[Diprivan versus midazolam in combined anaesthesia with ketamin for minor gynecological surgery].
Topics: Abortion, Induced; Adult; Anesthesia; Anesthetics, Intravenous; Drug Administration Schedule; Drug T | 2007 |
Subanaesthetic ketamine spares postoperative morphine and controls pain better than standard morphine does alone in orthopaedic-oncological patients.
Topics: Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Bone Neoplasms; Double-Blind Method; Drug | 2008 |
Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study.
Topics: Abdomen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Double-Blind Method; D | 2008 |
Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study.
Topics: Abdomen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Double-Blind Method; D | 2008 |
Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study.
Topics: Abdomen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Double-Blind Method; D | 2008 |
Postoperative ketamine administration decreases morphine consumption in major abdominal surgery: a prospective, randomized, double-blind, controlled study.
Topics: Abdomen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Double-Blind Method; D | 2008 |
The use of a ketamine-propofol combination during monitored anesthesia care.
Topics: Adult; Aged; Anesthesia, Local; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemod | 2000 |
Supplementing desflurane-remifentanil anesthesia with small-dose ketamine reduces perioperative opioid analgesic requirements.
Topics: Adjuvants, Anesthesia; Aged; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Inhalation; | 2002 |
12 other studies available for ketamine and Emesis, Postoperative
| Article | Year |
|---|---|
Anaesthesia administered as S(+)-ketamine for cardiac intervention in children with common congenital heart disease.
Topics: Anesthesia; Child; Heart Defects, Congenital; Humans; Ketamine; Postoperative Nausea and Vomiting; P | 2022 |
Multimodal analgesia practices for knee and hip arthroplasties in the Netherlands. A prospective observational study from the PAIN OUT registry.
Topics: Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arth | 2022 |
Preanesthetic nebulized ketamine vs preanesthetic oral ketamine for sedation and postoperative pain management in children for elective surgery: A retrospective analysis for effectiveness and safety.
Topics: Analgesics; Antiemetics; Child; Child, Preschool; Elective Surgical Procedures; Female; Humans; Keta | 2021 |
[Opioid-sparing effect of ketamine during tonsillectomy in children].
Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Child; Child, Preschool; Drug Evalu | 2013 |
The effects of intrathecal and systemic adjuvants on subarachnoid block.
Topics: Adjuvants, Anesthesia; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic alpha-Agonist | 2014 |
Comparison of ketamine-propofol and remifentanil in terms of hemodynamic variables and patient satisfaction during monitored anaesthesia care.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Intravenous; | 2016 |
Prophylactic antiemetics in oral and maxillofacial surgery: a requiem?
Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Anesthetics, Dissociative; Anesthe | 2009 |
Anticholinergics and ketamine sedation in children: a secondary analysis of atropine versus glycopyrrolate.
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Atropine; Chi-Square Distribution; Child; Consciou | 2010 |
Breast augmentation and augmentation-mastopexy with local anesthesia and intravenous sedation.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Local; Anesthetics, Intravenous; An | 2012 |
Ketamine and postoperative nausea and vomiting: role of the morphine-sparing effect.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Dose-Response Relationship, Drug; Excitatory Amino Acid | 2012 |
Adverse events and behavioral reactions related to ketamine based anesthesia for anorectal manometry in children.
Topics: Anal Canal; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, | 2008 |
[Anesthetic management of a child with congenital sensory neuropathy with anhydrosis].
Topics: Adolescent; Anesthesia, Intravenous; Droperidol; Electroencephalography; Femoral Fractures; Heredita | 2001 |