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ketamine and Dyskinesia, Drug-Induced

ketamine has been researched along with Dyskinesia, Drug-Induced in 14 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"Dextromethorphan was more effective than ketamine in potentiating morphine-induced antinociception."1.30Comparison of ketamine and dextromethorphan in potentiating the antinociceptive effect of morphine in rats. ( Hedman, U; Plesan, A; Wiesenfeld-Hallin, Z; Xu, XJ, 1998)
"The purpose of this article is to document that ketamine hydrochloride, administered at an anesthetic dosage of about 100 mg/kg, produces tongue contractile activity in the rat."1.27Ketamine as a pharmacological model for tongue dyskinesia. ( Aldes, LD; Chronister, RB; Marco, LA; Prater, SR, 1988)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's4 (28.57)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Pottenger, AE1
Bartlett, MJ4
Sherman, SJ4
Falk, T4
Morrison, HW1
Flores, AJ1
Ye, T2
Smidt, SI1
Dollish, HK1
Stancati, JA1
Farrell, DC1
Parent, KL2
Doyle, KP1
Besselsen, DG1
Heien, ML2
Cowen, SL2
Steece-Collier, K1
Joseph, RM1
LePoidevin, LM1
Laude, ND1
Lazarus, LB1
Estevez, M1
Bimpisidis, Z1
Öberg, CM1
Maslava, N1
Cenci, MA1
Lundblad, C1
Hans, ML1
Maxwell, C1
Ehrlichman, RS1
Metzger, K1
Liang, Y1
Siegel, SJ1
Lowman, AM1
Khanna, JM1
Morato, GS1
Chau, A1
Shah, G1
Plesan, A1
Hedman, U1
Xu, XJ1
Wiesenfeld-Hallin, Z1
Marco, LA6
Joshi, RS3
Cepeda, NJ1
Rhyne, DB1
Reed, TF3
Aldes, LD4
Chronister, RB4
Pendleton, R1
Brigham, TE1
Prater, SR1

Other Studies

14 other studies available for ketamine and Dyskinesia, Drug-Induced

ArticleYear
Evaluation of microglia in a rodent model of Parkinson's disease primed with L-DOPA after sub-anesthetic ketamine treatment.
    Neuroscience letters, 2021, 11-20, Volume: 765

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Corpus Striatum; Disease Models, A

2021
Preclinical evidence in support of repurposing sub-anesthetic ketamine as a treatment for L-DOPA-induced dyskinesia.
    Experimental neurology, 2020, Volume: 333

    Topics: Anesthetics, Dissociative; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Dendrit

2020
Spectral signatures of L-DOPA-induced dyskinesia depend on L-DOPA dose and are suppressed by ketamine.
    Experimental neurology, 2021, Volume: 340

    Topics: Analgesics; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induce

2021
Long-term effect of sub-anesthetic ketamine in reducing L-DOPA-induced dyskinesias in a preclinical model.
    Neuroscience letters, 2016, Jan-26, Volume: 612

    Topics: Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Ketamine;

2016
Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l-DOPA in a rat model of Parkinson's disease.
    Experimental neurology, 2017, Volume: 292

    Topics: Anesthetics; Animals; Basal Ganglia; Cerebrovascular Circulation; Dyskinesia, Drug-Induced; Dyskines

2017
Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 83, Issue:2

    Topics: Animals; Anti-Dyskinesia Agents; Delayed-Action Preparations; Drug Delivery Systems; Dyskinesia, Dru

2007
D-cycloserine enhances rapid tolerance to ethanol motor incoordination.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Animals; Central Nervous System Depressants; Cycloserine; Dose-Response Relationship, Drug; Drug Tol

1995
Comparison of ketamine and dextromethorphan in potentiating the antinociceptive effect of morphine in rats.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:4

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Antitussive Agents; C

1998
A ketamine-induced rat model of tardive dyskinesia.
    Progress in neurobiology, 1992, Volume: 38, Issue:6

    Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dyskinesia, Drug-Induced; Haloperidol

1992
Unitary correlates of linguo-pharyngeal events in a dyskinetic rat model.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3

    Topics: Animals; Deglutition; Dyskinesia, Drug-Induced; Electric Stimulation; Hypoglossal Nerve; Ketamine; L

1991
Metoclopramide fails to suppress linguopharyngeal events in a rat dyskinesia model.
    The Journal of neuropsychiatry and clinical neurosciences, 1989,Winter, Volume: 1, Issue:1

    Topics: Animals; Deglutition; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Ind

1989
Ketamine-induced tongue protrusions in rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 94, Issue:1

    Topics: Animals; Deglutition; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Hypoglo

1989
Ketamine as a pharmacological model for tongue dyskinesia.
    Biological psychiatry, 1988, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Dyskinesia, Drug-Induced; Female; Ketamine; Rats; Rats, Inbred Strains; Tongue

1988
An electrographic characterization of ketamine-induced linguopharyngeal motor activity.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:2

    Topics: Animals; Deglutition; Dyskinesia, Drug-Induced; Electromyography; Female; Haloperidol; Ketamine; Rat

1988