Page last updated: 2024-10-29

ketamine and Diabetic Neuropathies

ketamine has been researched along with Diabetic Neuropathies in 4 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"In mixed neuropathic pain, case series reports suggest a favourable response rate, but are limited by trial characteristics."5.43Topical amitriptyline and ketamine for post-herpetic neuralgia and other forms of neuropathic pain. ( Sawynok, J; Zinger, C, 2016)
"In mixed neuropathic pain, case series reports suggest a favourable response rate, but are limited by trial characteristics."1.43Topical amitriptyline and ketamine for post-herpetic neuralgia and other forms of neuropathic pain. ( Sawynok, J; Zinger, C, 2016)
"In morphine-only infusion rats, hyperalgesia and opioid insensitivity were both increased."1.42Long-Term Antihyperalgesic and Opioid-Sparing Effects of 5-Day Ketamine and Morphine Infusion ("Burst Ketamine") in Diabetic Neuropathic Rats. ( Broadbear, JH; Goodchild, CS; Kolosov, A; Mak, P, 2015)
" Studying its effects in clinics can be expected to increase our knowledge necessary for the development of new, effective, and safe "antineuralgic drug."1.35Side effects of ketamine in the long-term treatment of neuropathic pain. ( Cvrcek, P, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mak, P1
Broadbear, JH1
Kolosov, A1
Goodchild, CS1
Sawynok, J1
Zinger, C1
Baba, M1
Cvrcek, P1

Reviews

1 review available for ketamine and Diabetic Neuropathies

ArticleYear
[Progress in diagnosis of and therapy for diabetic polyneuropathies].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2004, Aug-10, Volume: 93, Issue:8

    Topics: Achilles Tendon; Aldehyde Reductase; Antidepressive Agents, Tricyclic; Diabetic Neuropathies; Diagno

2004

Other Studies

3 other studies available for ketamine and Diabetic Neuropathies

ArticleYear
Long-Term Antihyperalgesic and Opioid-Sparing Effects of 5-Day Ketamine and Morphine Infusion ("Burst Ketamine") in Diabetic Neuropathic Rats.
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:9

    Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal;

2015
Topical amitriptyline and ketamine for post-herpetic neuralgia and other forms of neuropathic pain.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:4

    Topics: Administration, Topical; Amitriptyline; Analgesics; Animals; Diabetic Neuropathies; Drug Combination

2016
Side effects of ketamine in the long-term treatment of neuropathic pain.
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Analgesics; Diabetic Neuropathies; Drug Administration Schedule; Female; Follow-U

2008