ketamine has been researched along with Craniofacial Pain in 10 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The analgesic effect of the N-methyl-D-aspartate (NMDA) receptor blocker ketamine in 17 patients (13 females and four males, age 32-88 years) who had suffered neuropathic orofacial pain for time periods ranging from 6 months to 28 years was examined." | 9.09 | Interindividual differences in the analgesic response to ketamine in chronic orofacial pain. ( Rabben, T; Øye, I, 2001) |
| "We examined the analgesic effect of racemic ketamine and its 2 enantiomers in 16 female patients (age: 20-29 years) suffering acute pain after oral surgery and in 7 female patients (age: 42-79 years) suffering chronic neuropathic orofacial pain." | 7.69 | Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain. ( Mathisen, LC; Skjelbred, P; Skoglund, LA; Øye, I, 1995) |
| "Ketamine has garnered increased interest for its promising applications in chronic pain treatment, particularly in cases where conventional therapies have proven insufficient." | 5.91 | Ketamine for atypical facial pain and hormonal dysregulation: a case report. ( Darwish, Y; Mahesh, K; Van, S; Willeford, S, 2023) |
| "The analgesic effect of the N-methyl-D-aspartate (NMDA) receptor blocker ketamine in 17 patients (13 females and four males, age 32-88 years) who had suffered neuropathic orofacial pain for time periods ranging from 6 months to 28 years was examined." | 5.09 | Interindividual differences in the analgesic response to ketamine in chronic orofacial pain. ( Rabben, T; Øye, I, 2001) |
| "The clinical efficacy of the noncompetitive N-methyl-d-aspartate receptor antagonist ketamine for treating orofacial pain has already been reported." | 3.72 | Synergistic antinociceptive effects of ketamine and morphine in the orofacial capsaicin test in the rat. ( Alvarez, P; Hernández, A; Paeile, C; Pelissier, T; Saavedra, G, 2003) |
| "We examined the analgesic effect of racemic ketamine and its 2 enantiomers in 16 female patients (age: 20-29 years) suffering acute pain after oral surgery and in 7 female patients (age: 42-79 years) suffering chronic neuropathic orofacial pain." | 3.69 | Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain. ( Mathisen, LC; Skjelbred, P; Skoglund, LA; Øye, I, 1995) |
| "ketamine bolus, were treated with 0." | 2.76 | A strategy for conversion from subcutaneous to oral ketamine in cancer pain patients: effect of a 1:1 ratio. ( Benítez-Rosario, MA; Feria, M; González-Guillermo, T; Salinas-Martín, A, 2011) |
| "Ketamine has garnered increased interest for its promising applications in chronic pain treatment, particularly in cases where conventional therapies have proven insufficient." | 1.91 | Ketamine for atypical facial pain and hormonal dysregulation: a case report. ( Darwish, Y; Mahesh, K; Van, S; Willeford, S, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Darwish, Y | 1 |
| Willeford, S | 1 |
| Mahesh, K | 1 |
| Van, S | 1 |
| Matsuura, N | 1 |
| Shibukawa, Y | 1 |
| Kato, M | 1 |
| Ichinohe, T | 1 |
| Suzuki, T | 1 |
| Kaneko, Y | 1 |
| Carter, MJ | 1 |
| Gibbins, J | 1 |
| Senior-Smith, G | 1 |
| Thomas, S | 1 |
| Guest, P | 1 |
| Forbes, K | 1 |
| Burgos, E | 1 |
| Pascual, D | 1 |
| Martín, MI | 1 |
| Goicoechea, C | 1 |
| Alstergren, P | 1 |
| Ernberg, M | 1 |
| Nilsson, M | 1 |
| Hajati, AK | 1 |
| Sessle, BJ | 1 |
| Kopp, S | 1 |
| Sakamoto, E | 1 |
| Shiiba, S | 1 |
| Noma, N | 1 |
| Okada-Ogawa, A | 1 |
| Shinozaki, T | 1 |
| Kobayashi, A | 1 |
| Kamo, H | 1 |
| Koike, K | 1 |
| Imamura, Y | 1 |
| Benítez-Rosario, MA | 1 |
| Salinas-Martín, A | 1 |
| González-Guillermo, T | 1 |
| Feria, M | 1 |
| Alvarez, P | 1 |
| Saavedra, G | 1 |
| Hernández, A | 1 |
| Paeile, C | 1 |
| Pelissier, T | 1 |
| Mathisen, LC | 1 |
| Skjelbred, P | 1 |
| Skoglund, LA | 1 |
| Øye, I | 2 |
| Rabben, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Naloxone Block of Low-dose (Analgetic Dose) Ketamine[NCT00921765] | Phase 4 | 3 participants (Actual) | Interventional | 2009-12-31 | Terminated (stopped due to Problems with patient recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for ketamine and Craniofacial Pain
| Article | Year |
|---|---|
Glutamate-induced temporomandibular joint pain in healthy individuals is partially mediated by peripheral NMDA receptors.
Topics: Adult; Area Under Curve; Double-Blind Method; Estradiol; Excitatory Amino Acid Antagonists; Excitato | 2010 |
A strategy for conversion from subcutaneous to oral ketamine in cancer pain patients: effect of a 1:1 ratio.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Dose-Response Relationship, Drug; | 2011 |
Interindividual differences in the analgesic response to ketamine in chronic orofacial pain.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics | 2001 |
7 other studies available for ketamine and Craniofacial Pain
| Article | Year |
|---|---|
Ketamine for atypical facial pain and hormonal dysregulation: a case report.
Topics: Analgesics; Facial Pain; Humans; Hydrocortisone; Ketamine; Receptors, N-Methyl-D-Aspartate | 2023 |
Ketamine, not fentanyl, suppresses pain-related magnetic fields associated with trigeminally innervated area following CO2 laser stimulation.
Topics: Adult; Analgesics; Facial Pain; Fentanyl; Humans; Ketamine; Lasers, Gas; Magnetoencephalography; Mal | 2008 |
Ketamine: does it have a role in palliative sedation?
Topics: Analgesics; Facial Pain; Humans; Ketamine; Male; Palliative Care; Tongue Neoplasms; Treatment Outcom | 2008 |
Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Anti-Inflammatory Agents, Non-St | 2010 |
A possible case of complex regional pain syndrome in the orofacial region.
Topics: Aged; Anesthetics, Dissociative; Causalgia; Facial Pain; GABA Modulators; Humans; Injections, Intrav | 2010 |
Synergistic antinociceptive effects of ketamine and morphine in the orofacial capsaicin test in the rat.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Comb | 2003 |
Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain.
Topics: Acute Disease; Adult; Aged; Chronic Disease; Facial Pain; Female; Follow-Up Studies; Humans; Inciden | 1995 |