ketamine has been researched along with Craniocerebral Trauma in 13 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine is considered a stable induction agent for rapid sequence induction; however, hypotension rates up to 24% are reported." | 7.83 | Hemodynamic Response After Rapid Sequence Induction With Ketamine in Out-of-Hospital Patients at Risk of Shock as Defined by the Shock Index. ( Burns, B; Habig, K; Heldreich, C; Kruit, N; Miller, M; Reid, C; Ware, S, 2016) |
| "Ketamine is considered a stable induction agent for rapid sequence induction; however, hypotension rates up to 24% are reported." | 3.83 | Hemodynamic Response After Rapid Sequence Induction With Ketamine in Out-of-Hospital Patients at Risk of Shock as Defined by the Shock Index. ( Burns, B; Habig, K; Heldreich, C; Kruit, N; Miller, M; Reid, C; Ware, S, 2016) |
| "Ketamine sedation has not been reported to be widely used as a pharmacological behavioural management strategy to facilitate the treatment of acute paediatric oro-dental trauma." | 1.56 | Safety and effectiveness of intramuscular ketamine sedation in the management of children with oro-dental trauma in a paediatric emergency department. ( Chay, PL; Tham, LP; Yee, R, 2020) |
| "Ketamine has been historically contraindicated for its use in head injury patients, since an increase of intracranial pressure (ICP) was reported; nevertheless, its use was recently suggested in neurosurgical patients." | 1.39 | Racemic ketamine in adult head injury patients: use in endotracheal suctioning. ( Annetta, MG; Antonelli, M; Bocci, MG; Caricato, A; De Waure, C; Pennisi, MA; Pitoni, S; Sandroni, C; Tersali, A, 2013) |
| "Group 3 (n = 10) received head trauma and intravenous (IV) 2 microgr/kg nimodipine." | 1.31 | Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. ( Ak, A; Duman, A; Oğun, CO; Ustün, ME; Vatansev, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Bebarta, VS | 1 |
| Mora, AG | 1 |
| Bebarta, EK | 1 |
| Reeves, LK | 1 |
| Maddry, JK | 2 |
| Schauer, SG | 2 |
| Lairet, JR | 1 |
| Hill, GJ | 1 |
| April, MD | 1 |
| Yee, R | 1 |
| Chay, PL | 1 |
| Tham, LP | 1 |
| Caricato, A | 1 |
| Tersali, A | 1 |
| Pitoni, S | 1 |
| De Waure, C | 1 |
| Sandroni, C | 1 |
| Bocci, MG | 1 |
| Annetta, MG | 1 |
| Pennisi, MA | 1 |
| Antonelli, M | 1 |
| Miller, M | 1 |
| Kruit, N | 1 |
| Heldreich, C | 1 |
| Ware, S | 1 |
| Habig, K | 1 |
| Reid, C | 1 |
| Burns, B | 1 |
| Filanovsky, Y | 1 |
| Miller, P | 1 |
| Kao, J | 1 |
| Urwin, SC | 1 |
| Menon, DK | 1 |
| Sehdev, RS | 1 |
| Symmons, DA | 1 |
| Kindl, K | 1 |
| Gunning, M | 1 |
| Perkins, Z | 1 |
| Quinn, T | 1 |
| Miyazato, H | 1 |
| Skinner, RD | 1 |
| Cobb, M | 1 |
| Andersen, B | 1 |
| Garcia-Rill, E | 1 |
| Ustün, ME | 1 |
| Duman, A | 1 |
| Oğun, CO | 1 |
| Vatansev, H | 1 |
| Ak, A | 1 |
| Beckman, DL | 1 |
| Bean, JW | 1 |
| Baslock, DR | 1 |
| Zook, EG | 1 |
| Roesch, RP | 1 |
| Thompson, LW | 1 |
| Bennett, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Study of Induction Medications Used in the Rapid Sequence Intubation of Trauma Patients and a Comparison of Effects on Outcomes[NCT04291521] | 7,000 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for ketamine and Craniocerebral Trauma
| Article | Year |
|---|---|
Myth: Ketamine should not be used as an induction agent for intubation in patients with head injury.
Topics: Anesthesia, General; Anesthetics, Dissociative; Animals; Contraindications; Craniocerebral Trauma; H | 2010 |
Comparative tolerability of sedative agents in head-injured adults.
Topics: Antipsychotic Agents; Barbiturates; Benzodiazepines; Craniocerebral Trauma; Drug Tolerance; Etomidat | 2004 |
Ketamine for rapid sequence induction in patients with head injury in the emergency department.
Topics: Anesthesia; Anesthetics, Dissociative; Animals; Cerebrovascular Circulation; Craniocerebral Trauma; | 2006 |
10 other studies available for ketamine and Craniocerebral Trauma
| Article | Year |
|---|---|
Prehospital Use of Ketamine in the Combat Setting: A Sub-Analysis of Patients With Head Injuries Evaluated in the Prospective Life Saving Intervention Study.
Topics: Adult; Afghanistan; Craniocerebral Trauma; Emergency Medical Services; Female; Humans; Ketamine; Mal | 2020 |
Prehospital ketamine administration to pediatric trauma patients with head injuries in combat theaters.
Topics: Adolescent; Analgesia; Child; Child, Preschool; Craniocerebral Trauma; Emergency Medical Services; F | 2019 |
Safety and effectiveness of intramuscular ketamine sedation in the management of children with oro-dental trauma in a paediatric emergency department.
Topics: Analgesics; Anesthesia; Child; Child, Preschool; Conscious Sedation; Craniocerebral Trauma; Emergenc | 2020 |
Racemic ketamine in adult head injury patients: use in endotracheal suctioning.
Topics: Adult; Anesthetics, Dissociative; Craniocerebral Trauma; Hemodynamics; Humans; Hypnotics and Sedativ | 2013 |
Hemodynamic Response After Rapid Sequence Induction With Ketamine in Out-of-Hospital Patients at Risk of Shock as Defined by the Shock Index.
Topics: Adult; Aged; Analgesics; Blood Pressure; Craniocerebral Trauma; Emergency Medical Services; Female; | 2016 |
Trench entrapment: is ketamine safe to use for sedation in head injury?
Topics: Adult; Anesthetics, Dissociative; Conscious Sedation; Craniocerebral Trauma; Glasgow Coma Scale; Hum | 2007 |
Midlatency auditory-evoked potentials in the rat: effects of interventions that modulate arousal.
Topics: Anesthetics; Animals; Arousal; Craniocerebral Trauma; Ethanol; Evoked Potentials, Auditory; Halothan | 1999 |
Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Brain; Brain Injuries; Carbon Dioxide; | 2001 |
Neurogenic influence on pulmonary compliance.
Topics: Anesthesia; Animals; Atropine; Body Weight; Craniocerebral Trauma; Electric Stimulation; Haplorhini; | 1974 |
Ketamine anesthesia in pediatric plastic surgery.
Topics: Age Factors; Analgesics; Anesthesia, Intravenous; Burns; Child; Child, Preschool; Craniocerebral Tra | 1971 |