Page last updated: 2024-10-29

ketamine and Colonic Neoplasms

ketamine has been researched along with Colonic Neoplasms in 5 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"Although postoperative pain measurements did not differ, postoperative epidural treatment (intravenous-epidural) was less effective to prevent residual pain at 1 yr (11%; P = 0."2.71Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery. ( De Kock, M; Lavand'homme, P; Waterloos, H, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuchs, K1
Kukuk, D1
Reischl, G1
Föller, M1
Eichner, M1
Reutershan, J1
Lang, F1
Röcken, M1
Pichler, BJ1
Kneilling, M1
Shimoyama, N1
Takahashi, H1
Shimoyama, M1
Lavand'homme, P1
De Kock, M1
Waterloos, H1
Chung, WJ1
Pharo, GH1
Gleason, WA1
Goldstein, PD1
Shatz, BA1
Tedesco, FJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transversus Abdominis Plane (TAP) Block for Cesarean Section[NCT01015807]90 participants (Actual)Interventional2009-11-30Completed
Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543]90 participants (Actual)Interventional2014-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Wound Hyperalgesia Index (WHA) Assessed 48 Hrs After Block Placement in the Different Groups

Determine which of three different TAP formulations (Placebo, TAP, Clo-TAP) has the most beneficial effect on the postoperative area of hyperalgesia 48hrs after the start of the cesarean section. The smaller the area of WHA, assessed in cm2, the better the outcome. Area sizes may range from 0 to any size. (NCT01015807)
Timeframe: 48hrs after CS

Interventioncm^2 (Mean)
Placebo1.07
TAP (Bupi)1.27
Clo-TAP (Bupi + Clon)0.74

Reviews

1 review available for ketamine and Colonic Neoplasms

ArticleYear
[Palliative care for colon cancer patients as total pain management].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Analgesia, Epidural; Anticonvulsants; Antidepressive Agents; Colonic Neoplasms; Drug Therapy, Combin

2003

Trials

1 trial available for ketamine and Colonic Neoplasms

ArticleYear
Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Colonic Neoplasms; Double-Blind Method; Female; Humans; Hyperalges

2005
Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Colonic Neoplasms; Double-Blind Method; Female; Humans; Hyperalges

2005
Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Colonic Neoplasms; Double-Blind Method; Female; Humans; Hyperalges

2005
Intraoperative epidural analgesia combined with ketamine provides effective preventive analgesia in patients undergoing major digestive surgery.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Adult; Aged; Analgesia, Epidural; Colonic Neoplasms; Double-Blind Method; Female; Humans; Hyperalges

2005

Other Studies

3 other studies available for ketamine and Colonic Neoplasms

ArticleYear
Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:5

    Topics: Anesthesia; Animals; Ankle; Arthritis; Artifacts; Biological Transport; Carbon Dioxide; Cell Line, T

2012
Successful use of ketamine infusion in the treatment of intractable cancer pain in an outpatient.
    Journal of pain and symptom management, 2007, Volume: 33, Issue:1

    Topics: Adenocarcinoma; Adult; Ambulatory Care; Analgesics; Colonic Neoplasms; Female; Humans; Infusions, In

2007
Colonoscopic removal of juvenile colonic polyps.
    Journal of pediatric surgery, 1975, Volume: 10, Issue:4

    Topics: Barium Sulfate; Child; Child, Preschool; Colonic Neoplasms; Diazepam; Endoscopy; Enema; Hematocrit;

1975