Page last updated: 2024-10-29

ketamine and Cirrhosis

ketamine has been researched along with Cirrhosis in 10 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Ketamine-induced cystitis (KIC) is a disease caused by ketamine that can cause lower urinary tract symptoms (LUTS)."8.12Transcriptomic analysis of bladder tissue in a rat model of ketamine-induced bladder fibrosis. ( Li, H; Li, K; Tang, Z; Wang, Z; Zhu, Q, 2022)
"To investigate the mechanism of bladder nerve hyperplasia and fibrosis in the patients with ketamine-associated cystitis (KC)."7.91Upregulation of neurotrophins and transforming growth factor-β expression in the bladder may lead to nerve hyperplasia and fibrosis in patients with severe ketamine-associated cystitis. ( Birder, LA; Hsu, YH; Jhang, JF; Kuo, HC; Wang, HJ, 2019)
"Bladder wall fibrosis is a major complication of ketamine-induced cystitis (KC), but the underlying pathogenesis is poorly understood."7.85Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1. ( Chen, J; Chen, Y; Gu, D; Wang, J; Wu, P; Zhang, G; Zhao, J, 2017)
"Abuse of the hallucinogenic drug ketamine promotes the development of lower urinary tract symptoms that resemble interstitial cystitis."7.83Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder. ( Choi, SJ; Choo, MS; Heo, J; Kim, A; Kim, SW; Kim, Y; Lee, S; Lim, J; Oh, W; Shin, DM; Shin, JH; Song, M; Yoon, SJ; Yu, HY, 2016)
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine."7.70Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999)
"Ketamine-treated rats were found to display bladder hyperactivity."5.42Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. ( Chuang, SM; Ho, WT; Jang, MY; Juan, YS; Lee, YL; Lin, RJ; Liu, KM; Long, CY; Lu, JH; Lu, MC; Wang, CC; Wu, WJ, 2015)
"Ketamine-induced cystitis (KIC) is a disease caused by ketamine that can cause lower urinary tract symptoms (LUTS)."4.12Transcriptomic analysis of bladder tissue in a rat model of ketamine-induced bladder fibrosis. ( Li, H; Li, K; Tang, Z; Wang, Z; Zhu, Q, 2022)
"To investigate the mechanism of bladder nerve hyperplasia and fibrosis in the patients with ketamine-associated cystitis (KC)."3.91Upregulation of neurotrophins and transforming growth factor-β expression in the bladder may lead to nerve hyperplasia and fibrosis in patients with severe ketamine-associated cystitis. ( Birder, LA; Hsu, YH; Jhang, JF; Kuo, HC; Wang, HJ, 2019)
"Bladder wall fibrosis is a major complication of ketamine-induced cystitis (KC), but the underlying pathogenesis is poorly understood."3.85Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1. ( Chen, J; Chen, Y; Gu, D; Wang, J; Wu, P; Zhang, G; Zhao, J, 2017)
"Abuse of the hallucinogenic drug ketamine promotes the development of lower urinary tract symptoms that resemble interstitial cystitis."3.83Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder. ( Choi, SJ; Choo, MS; Heo, J; Kim, A; Kim, SW; Kim, Y; Lee, S; Lim, J; Oh, W; Shin, DM; Shin, JH; Song, M; Yoon, SJ; Yu, HY, 2016)
"Chronic treatment with ketamine caused significant ventricular myocardial apoptosis, fibrosis and sympathetic sprouting, which altered the electrophysiological properties of the heart and increased its susceptibility to malignant arrhythmia that may lead to sudden cardiac death."3.78Ketamine-induced ventricular structural, sympathetic and electrophysiological remodelling: pathological consequences and protective effects of metoprolol. ( Dong, DL; Geng, JQ; Gong, YT; Gong, ZH; Han, CL; Li, WM; Li, Y; Liu, GZ; Liu, L; Pan, ZW; Sheng, L; Shi, J; Sun, DH; Tan, XY; Yang, BF, 2012)
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine."3.70Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999)
"Ketamine-treated rats were found to display bladder hyperactivity."1.42Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum. ( Chuang, SM; Ho, WT; Jang, MY; Juan, YS; Lee, YL; Lin, RJ; Liu, KM; Long, CY; Lu, JH; Lu, MC; Wang, CC; Wu, WJ, 2015)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Li, H1
Li, K1
Zhu, Q1
Tang, Z1
Wang, Z1
Jhang, JF1
Wang, HJ1
Hsu, YH1
Birder, LA1
Kuo, HC1
Wang, J1
Chen, Y1
Gu, D1
Zhang, G1
Chen, J1
Zhao, J1
Wu, P1
Liu, KM1
Chuang, SM1
Long, CY1
Lee, YL1
Wang, CC1
Lu, MC1
Lin, RJ1
Lu, JH1
Jang, MY1
Wu, WJ1
Ho, WT1
Juan, YS1
Song, M2
Yu, HY2
Chun, JY1
Shin, DM2
Song, SH1
Choo, MS2
Song, YS1
Shen, CH1
Wang, SC1
Wang, ST1
Lin, SM1
Wu, JD1
Lin, CT1
Liu, YW1
Kim, A1
Heo, J1
Shin, JH1
Lim, J1
Yoon, SJ1
Kim, Y1
Lee, S1
Kim, SW1
Oh, W1
Choi, SJ1
Li, Y1
Shi, J1
Yang, BF1
Liu, L1
Han, CL1
Li, WM1
Dong, DL1
Pan, ZW1
Liu, GZ1
Geng, JQ1
Sheng, L1
Tan, XY1
Sun, DH1
Gong, ZH1
Gong, YT1
Tao, Y1
Chen, XP1
Qin, ZH1
Marini, RP1
Li, X1
Harpster, NK1
Dangler, C1

Other Studies

10 other studies available for ketamine and Cirrhosis

ArticleYear
Transcriptomic analysis of bladder tissue in a rat model of ketamine-induced bladder fibrosis.
    Neurourology and urodynamics, 2022, Volume: 41, Issue:3

    Topics: Animals; Cystitis; Female; Fibrosis; Gene Expression Profiling; Humans; Ketamine; Male; Rats; Rats,

2022
Upregulation of neurotrophins and transforming growth factor-β expression in the bladder may lead to nerve hyperplasia and fibrosis in patients with severe ketamine-associated cystitis.
    Neurourology and urodynamics, 2019, Volume: 38, Issue:8

    Topics: Adult; Aged; Brain-Derived Neurotrophic Factor; Cystitis; Excitatory Amino Acid Antagonists; Female;

2019
Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1.
    American journal of physiology. Renal physiology, 2017, Oct-01, Volume: 313, Issue:4

    Topics: Analgesics; Animals; Cell Line; Cystitis; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Fi

2017
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
    American journal of physiology. Renal physiology, 2015, Aug-15, Volume: 309, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Cystitis; Disease Model

2015
The fibrosis of ketamine, a noncompetitive N-methyl-d-aspartic acid receptor antagonist dose-dependent change in a ketamine-induced cystitis rat model.
    Drug and chemical toxicology, 2016, Volume: 39, Issue:2

    Topics: Animals; Cystitis; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid A

2016
Evaluation of urinary bladder fibrogenesis in a mouse model of long-term ketamine injection.
    Molecular medicine reports, 2016, Volume: 14, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Fibrosis; Injections, Intraperitoneal; Ketamine; Male; Mice

2016
Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder.
    Scientific reports, 2016, 08-02, Volume: 6

    Topics: Analgesics; Animals; Cells, Cultured; Cystitis; Disease Models, Animal; Fibrosis; Humans; Infant, Ne

2016
Ketamine-induced ventricular structural, sympathetic and electrophysiological remodelling: pathological consequences and protective effects of metoprolol.
    British journal of pharmacology, 2012, Volume: 165, Issue:6

    Topics: Analgesics; Animals; Apoptosis; Apoptosis Inducing Factor; Fibrosis; Heart Ventricles; Illicit Drugs

2012
A fatal chronic ketamine poisoning.
    Journal of forensic sciences, 2005, Volume: 50, Issue:1

    Topics: Adult; Anesthetics, Dissociative; Autopsy; Chronic Disease; Female; Fibrosis; Homicide; Humans; Keta

2005
Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits.
    Laboratory animal science, 1999, Volume: 49, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Antibodies, Viral; Cardiovascular Diseases; Coronavirus; Echocardi

1999