ketamine has been researched along with Chemical Dependence in 426 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component." | 8.90 | Ketamine for chronic pain: risks and benefits. ( Dahan, A; Martini, C; Niesters, M, 2014) |
| "To determine the diagnosis, treatment, and pathogenesis of ketamine-associated cystitis." | 8.89 | [Diagnosis and treatment of ketamine-associated cystitis: a report of 3 cases and literature review]. ( Ding, J; Huang, K; Huang, L; Li, D; Li, Y; Luo, K; Tang, Z; Wang, G; Zhou, J, 2013) |
| "Esketamine, the S-enantiomer of ketamine, has recently emerged as a therapy for treatment-resistant depression (TRD), showing both rapid antidepressant action and good efficacy and high safety." | 8.31 | Esketamine in treatment-resistant depression patients comorbid with substance-use disorder: A viewpoint on its safety and effectiveness in a subsample of patients from the REAL-ESK study. ( Andriola, I; Barlati, S; Bassetti, R; Chiappini, S; Clerici, M; d'Andrea, G; De Filippis, S; Dell'Osso, B; Di Nicola, M; Martinotti, G; Pettorruso, M; Sensi, S; Vita, A, 2023) |
| "This cross-sectional study evaluates trends in the number and weight of illicit ketamine seizures in the US from 2017 to 2022." | 8.31 | Trends in Illicit Ketamine Seizures in the US From 2017 to 2022. ( Carr, TH; Cottler, LB; Palamar, JJ; Rutherford, C; Wilkinson, ST, 2023) |
| "Over 28 months at two large community hospitals, all medical records were retrospectively searched for all patients age 18 years or greater with prehospital ketamine intramuscular (IM) administration for excited delirium and identified illicit and prescription substance co-ingestions." | 8.02 | Prehospital Ketamine Administration for Excited Delirium with Illicit Substance Co-Ingestion and Subsequent Intubation in the Emergency Department. ( Alter, SM; Clayton, LM; Hennekens, CH; Hughes, PG; Parks, DJ; Polley, SE; Shih, RD; Solano, JJ, 2021) |
| "A 29-year-old male patient with a 3-year history of ketamine inhalation, complaining of dysuria with frequency and urgency, was admitted." | 7.91 | Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male. ( Jin, Z; Liao, Z; Tang, Z; Wang, Z, 2019) |
| "We aimed to explore the correlation between ketamine abuse and lower urinary tract symptoms (LUTS) and epidemiology of ketamine cystitis." | 7.91 | A survey for ketamine abuse and its relation to the lower urinary tract symptoms in Taiwan. ( Cha, TL; Li, CC; Meng, E; Sun, GH; Wu, ST; Yu, DS, 2019) |
| "Young adults with longstanding ketamine abuse present with lower urinary tract symptoms (LUTSs), which may be accompanied by urinary tract infection (UTI)." | 7.91 | Epidemiologic characteristics and risk factors in patients with ketamine-associated lower urinary tract symptoms accompanied by urinary tract infection: A cross-sectional study. ( Gao, Y; Hong, F; Li, T; Liu, W; Wei, Y; Wu, J; Wu, W; Yang, J; Ye, L; Zhu, Q, 2019) |
| "Ketamine abuse is an emerging issue in many countries, and ketamine cystitis (KC) is a growing disease which more and more urologists may encounter with." | 7.88 | Complete reversal of the clinical symptoms and image morphology of ketamine cystitis after intravesical hyaluronic acid instillation: A case report. ( Cha, TL; Liu, CY; Ou, YL; Tsao, CW; Wu, ST, 2018) |
| "Bladder wall fibrosis is a major complication of ketamine-induced cystitis (KC), but the underlying pathogenesis is poorly understood." | 7.85 | Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1. ( Chen, J; Chen, Y; Gu, D; Wang, J; Wu, P; Zhang, G; Zhao, J, 2017) |
| "Chronic ketamine use leads to cognitive and affective deficits including depression." | 7.85 | Depression in chronic ketamine users: Sex differences and neural bases. ( Chen, CM; Duann, JR; Hung, CC; Lee, TS; Li, CR; Lin, CP; Zhang, S, 2017) |
| "Exposing to NMDAR receptor antagonists, such as ketamine, produces schizophrenia-like symptoms in humans and deteriorates symptoms in schizophrenia patients." | 7.81 | Relationship of serum levels of TNF-α, IL-6 and IL-18 and schizophrenia-like symptoms in chronic ketamine abusers. ( Deng, X; Ding, Y; Fan, N; He, H; Huang, X; Ke, X; Luo, Y; Ning, Y; Wang, D; Xu, K; Zhang, M, 2015) |
| "The aim of this study was to investigate and report the clinical spectrum and practical problems in the management of a cohort of patients presenting with lower urinary tract symptoms (LUTS) related to abuse of ketamine." | 7.80 | Ketamine cystitis: practical considerations in management. ( Chetwood, A; Coker, C; Misra, S; Thomas, P, 2014) |
| "Long-term ketamine abuse is known to affect the lower urinary tract and produce symptoms of cystitis." | 7.80 | Long-term ketamine abuse induces cystitis in rats by impairing the bladder epithelial barrier. ( Gu, D; Huang, J; Shan, Z; Wu, P; Yin, Y; Zheng, S, 2014) |
| "To evaluate the outcomes of augmentation cystoplasty in patients with bladder contractures secondary to chronic ketamine abuse." | 7.79 | Clinical outcomes of augmentation cystoplasty in patients suffering from ketamine-related bladder contractures. ( Chan, ES; Chiu, PK; Chu, PS; Hou, SS; Li, ML; Man, CW; Ng, CF, 2013) |
| " This peripheral nerve fascicle hyperplasia is likely to account for the extreme pain experienced by ketamine cystitis patients." | 7.79 | Nerve hyperplasia: a unique feature of ketamine cystitis. ( Baker, SC; Eardley, I; Fulford, S; Gillatt, D; Hinley, J; Marsh, F; Oxley, J; Southgate, J; Stahlschmidt, J, 2013) |
| "To investigate the use of a translated Chinese version of the pelvic pain and urgency/frequency symptom scale as an assessment and prognostic tool to evaluate the severity of street-ketamine-associated lower urinary tract symptoms and their reversibility after abstinence." | 7.78 | The Chinese version of the pelvic pain and urgency/frequency symptom scale: a useful assessment tool for street-ketamine abusers with lower urinary tract symptoms. ( Ma, WK; Ng, CM; To, KC; Yiu, MK, 2012) |
| "The aim of this study was to assess schizophrenia proneness and neurocognitive function in individuals dependent upon ketamine, cannabis and cocaine." | 7.78 | Neurocognitive function and schizophrenia-proneness in individuals dependent on ketamine, on high potency cannabis ('skunk') or on cocaine. ( Curran, HV; Duffin, S; Hunt, S; Mason, O; Monaghan, L; Morgan, CJ, 2012) |
| "A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse." | 7.74 | The destruction of the lower urinary tract by ketamine abuse: a new syndrome? ( Cheng, CH; Chu, PS; Chu, RW; Lau, FL; Ma, WK; Man, CW; Tse, JM; Wong, S; Wong, SC; Yiu, MK, 2008) |
| " A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported." | 7.68 | Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993) |
| "Ketamine usage can produce undesirable psychological manifestations including hallucinations and long-term psychotomimetic effects." | 7.01 | Current approaches for the treatment of ketamine-induced cystitis. ( Lehmann, C; Miab, ZR; Scott, C; Zhou, J, 2023) |
| "Ketamine has become increasingly recognized as a drug of recreational use." | 6.47 | Recreational ketamine: from pleasure to pain. ( Baker, SC; Cottrell, A; Fulford, S; Gillatt, D; Harris, M; Southgate, J; Wood, D; Woodhouse, C, 2011) |
| "We examined the association of lower urinary tract symptoms and levels of Nectin-4, a member of the cell adhesion molecules that is essential for maintaining the urothelium barrier in chronic ketamine abusers." | 5.62 | Increased Nectin-4 levels in chronic ketamine abusers and the relationship with lower urinary tract symptoms. ( Chang, HM; Chen, PY; Fang, CP; Hsu, YC; Huang, MC; Kuo, HW; Liu, TH; Liu, YL; Wu, CT, 2021) |
| "Ketamine abuse has become a global phenomenon in recent years." | 5.46 | Clinical Outcome of Augmentation Enterocystoplasty for Patients with Ketamine-induced Cystitis. ( Jhang, JF; Kuo, HC; Lee, YK, 2017) |
| "Ketamine is a recreational drug widely abused in East Asia and also in certain subpopulations of the United States." | 5.46 | Ketamine Abuse Syndrome: Hepatobiliary and Urinary Pathology Among Adolescents in Flushing, NY. ( Gordon, L; Kivovich, V; Wang, JW, 2017) |
| " The higher ketamine use frequency and dosage were associated with more severe depressive symptoms." | 5.43 | Profiling the psychotic, depressive and anxiety symptoms in chronic ketamine users. ( Deng, X; Ding, Y; Fan, N; He, H; Ke, X; Ning, Y; Rosenheck, R; Sun, B; Tang, W; Wang, D; Xu, K; Zhou, C, 2016) |
| "We found that ketamine leads to significantly greater mystical-type effects (by Hood Mysticism Scale) and dissociation (by Clinician Administered Dissociative States Scale) compared to the active control." | 5.41 | Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial. ( Azhari, N; Dakwar, E; Haug, NA; Rothberg, RL, 2021) |
| "Ketamine abuse may cause variable urinary tract injury." | 5.39 | Renal infarction secondary to ketamine abuse. ( Cha, TL; Chen, CL; Chen, JL; Meng, E; Tang, SH; Tsao, CW; Wu, ST, 2013) |
| "Ketamine is a dissociative anaesthetic agent that is still widely used in veterinary and human medicine." | 5.37 | Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series. ( Austin, AS; Freeman, JG; Krishnamoorthy, R; Lo, RS, 2011) |
| "Lorcaserin is a selective and potent serotonin 2C receptor subtype (5-HT(2C)) agonist under development for the treatment of obesity." | 5.15 | Evaluation of the abuse potential of lorcaserin, a serotonin 2C (5-HT2C) receptor agonist, in recreational polydrug users. ( Anderson, CM; Bartlett, C; Schoedel, KA; Sellers, EM; Shazer, RL; Shram, MJ, 2011) |
| "Ketamine is used acutely as a model of schizophrenia." | 5.12 | Semantic priming after ketamine acutely in healthy volunteers and following chronic self-administration in substance users. ( Blackburn, J; Brandner, B; Curran, HV; Morgan, CJ; Pepper, F; Rossell, SL; Smart, J, 2006) |
| "The anaesthetic ketamine is used to treat various chronic pain syndromes, especially those that have a neuropathic component." | 4.90 | Ketamine for chronic pain: risks and benefits. ( Dahan, A; Martini, C; Niesters, M, 2014) |
| "To determine the diagnosis, treatment, and pathogenesis of ketamine-associated cystitis." | 4.89 | [Diagnosis and treatment of ketamine-associated cystitis: a report of 3 cases and literature review]. ( Ding, J; Huang, K; Huang, L; Li, D; Li, Y; Luo, K; Tang, Z; Wang, G; Zhou, J, 2013) |
| "A major physical harm is ketamine induced ulcerative cystitis which, although its aetiology is unclear, seems particularly associated with chronic, frequent use of the drug." | 4.88 | Ketamine use: a review. ( Curran, HV; Morgan, CJ, 2012) |
| " The mechanism of action analysis revealed that ketamine directly targets multiple CUD-associated genes (BDNF, CNR1, DRD2, GABRA2, GABRB3, GAD1, OPRK1, OPRM1, SLC6A3, SLC6A4) and pathways implicated in neuroactive ligand-receptor interaction, cAMP signaling and cocaine abuse/dependence." | 4.31 | Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence-based prediction, expert evaluation, clinical corroboration and mechanism of action analyses. ( Davis, PB; Gao, Z; Ghitza, UE; Gorenflo, M; Kaelber, DC; Winhusen, TJ; Xu, R, 2023) |
| "Esketamine, the S-enantiomer of ketamine, has recently emerged as a therapy for treatment-resistant depression (TRD), showing both rapid antidepressant action and good efficacy and high safety." | 4.31 | Esketamine in treatment-resistant depression patients comorbid with substance-use disorder: A viewpoint on its safety and effectiveness in a subsample of patients from the REAL-ESK study. ( Andriola, I; Barlati, S; Bassetti, R; Chiappini, S; Clerici, M; d'Andrea, G; De Filippis, S; Dell'Osso, B; Di Nicola, M; Martinotti, G; Pettorruso, M; Sensi, S; Vita, A, 2023) |
| "This cross-sectional study evaluates trends in the number and weight of illicit ketamine seizures in the US from 2017 to 2022." | 4.31 | Trends in Illicit Ketamine Seizures in the US From 2017 to 2022. ( Carr, TH; Cottler, LB; Palamar, JJ; Rutherford, C; Wilkinson, ST, 2023) |
| "Ketamine is efficacious in treating treatment-resistant depression in medical settings and the drug was approved for such use by the US Federal Drug Administration in 2019." | 4.12 | Ketamine use in relation to depressive symptoms among high school seniors. ( Han, BH; Kumar, S; Palamar, JJ; Yang, KH, 2022) |
| " Differences in STI health (chlamydia, gonorrhoea, syphilis, HIV diagnoses), mental health (depression/anxiety) and internalised homonegativity between MSM using and not using GHB/GBL, crystal meth, mephedrone, cocaine or ketamine with sex in the last year were assessed descriptively and in a multivariate logistic regression model." | 4.12 | Health characteristics associated with chemsex among men who have sex with men: Results from a cross-sectional clinic survey in Norway. ( Amundsen, E; Berg, RC; Haugstvedt, Å; Skogen, V, 2022) |
| "Over 28 months at two large community hospitals, all medical records were retrospectively searched for all patients age 18 years or greater with prehospital ketamine intramuscular (IM) administration for excited delirium and identified illicit and prescription substance co-ingestions." | 4.02 | Prehospital Ketamine Administration for Excited Delirium with Illicit Substance Co-Ingestion and Subsequent Intubation in the Emergency Department. ( Alter, SM; Clayton, LM; Hennekens, CH; Hughes, PG; Parks, DJ; Polley, SE; Shih, RD; Solano, JJ, 2021) |
| "We included 104 patients with KD (76 males and 28 females) who received inpatient treatment for ketamine withdrawal and assessed them by using Beck Depression Inventory (BDI), Beck Anxiety Inventory, and a visual analog scale (VAS; 0-100 mm) for ketamine craving on day 2 to 3 of admission." | 3.96 | Association of Craving and Depressive Symptoms in Ketamine-Dependent Patients Undergoing Withdrawal Treatment. ( Chang, HM; Chen, CH; Chen, CK; Chen, LY; Huang, MC; Xu, K, 2020) |
| " Levels of the three markers did not correlate with ketamine use variables, craving, depression, or anxiety symptoms." | 3.96 | Chronic ketamine abuse is associated with orexin-A reduction and ACTH elevation. ( Chang, HM; Chen, CH; Chen, CK; Chen, LY; Huang, MC; Lin, SK; Xu, K, 2020) |
| "In this longitudinal study, 114 ketamine users completed clinical and cognitive assessments at both baseline and 12-week follow-up with the following instruments: Severity of Dependence Scale, Beck Depression Inventory (BDI), Anxiety Subscale of the Hospital Anxiety Depression Scale (HADSA), and a cognitive battery." | 3.91 | Recovery of cognitive functioning following abstinence from ketamine. ( Lane, HY; Lau, CG; Lin, SK; Tang, WK; Ungvari, GS, 2019) |
| "A 29-year-old male patient with a 3-year history of ketamine inhalation, complaining of dysuria with frequency and urgency, was admitted." | 3.91 | Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male. ( Jin, Z; Liao, Z; Tang, Z; Wang, Z, 2019) |
| "We aimed to explore the correlation between ketamine abuse and lower urinary tract symptoms (LUTS) and epidemiology of ketamine cystitis." | 3.91 | A survey for ketamine abuse and its relation to the lower urinary tract symptoms in Taiwan. ( Cha, TL; Li, CC; Meng, E; Sun, GH; Wu, ST; Yu, DS, 2019) |
| "Young adults with longstanding ketamine abuse present with lower urinary tract symptoms (LUTSs), which may be accompanied by urinary tract infection (UTI)." | 3.91 | Epidemiologic characteristics and risk factors in patients with ketamine-associated lower urinary tract symptoms accompanied by urinary tract infection: A cross-sectional study. ( Gao, Y; Hong, F; Li, T; Liu, W; Wei, Y; Wu, J; Wu, W; Yang, J; Ye, L; Zhu, Q, 2019) |
| "This study investigated the risk factors of ketamine associated-lower urinary tract symptoms (LUTS), such as duration of use, dosage of ketamine, co-occurring substance use of other psychoactive drugs, comorbidities, and depression." | 3.88 | Risk Factors of Lower Urinary Tract Syndrome among Ketamine Users. ( Chen, IC; Chen, WC; Hu, TC; Lee, MH; Lin, HY, 2018) |
| "Ketamine has been used to probe the biology of psychosis and cognitive dysfunction in humans." | 3.88 | Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia. ( Chen, CH; Chen, CK; Cheng, WJ; Huang, MC; Krystal, JH; Pietrzak, RH; Xu, K, 2018) |
| "Ketamine abuse is an emerging issue in many countries, and ketamine cystitis (KC) is a growing disease which more and more urologists may encounter with." | 3.88 | Complete reversal of the clinical symptoms and image morphology of ketamine cystitis after intravesical hyaluronic acid instillation: A case report. ( Cha, TL; Liu, CY; Ou, YL; Tsao, CW; Wu, ST, 2018) |
| "To evaluate the prevalence of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in the illicit male ketamine abusers (KA)." | 3.88 | Sexual and bladder dysfunction in male ketamine abusers: A large-scale questionnaire study. ( Chang, SJ; Chen, WS; Chen, YC; Hsu, WT; Jang, MY; Lee, KH; Yang, SS, 2018) |
| "Bladder wall fibrosis is a major complication of ketamine-induced cystitis (KC), but the underlying pathogenesis is poorly understood." | 3.85 | Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1. ( Chen, J; Chen, Y; Gu, D; Wang, J; Wu, P; Zhang, G; Zhao, J, 2017) |
| "Submucosal bladder inflammation was seen in 67% of the rats fed with 300 mg/kg illicit ketamine." | 3.85 | Oral ketamine induced pathological changes of the urinary tract in a rat model. ( Ali Mohd, M; Hasan, MS; Mohamad Wali, HA; Mun, KS; Ong, TA; Rajandram, R; Razack, AHA; Yap, NY, 2017) |
| "Chronic ketamine use leads to cognitive and affective deficits including depression." | 3.85 | Depression in chronic ketamine users: Sex differences and neural bases. ( Chen, CM; Duann, JR; Hung, CC; Lee, TS; Li, CR; Lin, CP; Zhang, S, 2017) |
| "Exposing to NMDAR receptor antagonists, such as ketamine, produces schizophrenia-like symptoms in humans and deteriorates symptoms in schizophrenia patients." | 3.81 | Relationship of serum levels of TNF-α, IL-6 and IL-18 and schizophrenia-like symptoms in chronic ketamine abusers. ( Deng, X; Ding, Y; Fan, N; He, H; Huang, X; Ke, X; Luo, Y; Ning, Y; Wang, D; Xu, K; Zhang, M, 2015) |
| "The aim of this study was to investigate and report the clinical spectrum and practical problems in the management of a cohort of patients presenting with lower urinary tract symptoms (LUTS) related to abuse of ketamine." | 3.80 | Ketamine cystitis: practical considerations in management. ( Chetwood, A; Coker, C; Misra, S; Thomas, P, 2014) |
| "Long-term ketamine abuse is known to affect the lower urinary tract and produce symptoms of cystitis." | 3.80 | Long-term ketamine abuse induces cystitis in rats by impairing the bladder epithelial barrier. ( Gu, D; Huang, J; Shan, Z; Wu, P; Yin, Y; Zheng, S, 2014) |
| "To evaluate the outcomes of augmentation cystoplasty in patients with bladder contractures secondary to chronic ketamine abuse." | 3.79 | Clinical outcomes of augmentation cystoplasty in patients suffering from ketamine-related bladder contractures. ( Chan, ES; Chiu, PK; Chu, PS; Hou, SS; Li, ML; Man, CW; Ng, CF, 2013) |
| " This peripheral nerve fascicle hyperplasia is likely to account for the extreme pain experienced by ketamine cystitis patients." | 3.79 | Nerve hyperplasia: a unique feature of ketamine cystitis. ( Baker, SC; Eardley, I; Fulford, S; Gillatt, D; Hinley, J; Marsh, F; Oxley, J; Southgate, J; Stahlschmidt, J, 2013) |
| "To investigate the use of a translated Chinese version of the pelvic pain and urgency/frequency symptom scale as an assessment and prognostic tool to evaluate the severity of street-ketamine-associated lower urinary tract symptoms and their reversibility after abstinence." | 3.78 | The Chinese version of the pelvic pain and urgency/frequency symptom scale: a useful assessment tool for street-ketamine abusers with lower urinary tract symptoms. ( Ma, WK; Ng, CM; To, KC; Yiu, MK, 2012) |
| "The aim of this study was to assess schizophrenia proneness and neurocognitive function in individuals dependent upon ketamine, cannabis and cocaine." | 3.78 | Neurocognitive function and schizophrenia-proneness in individuals dependent on ketamine, on high potency cannabis ('skunk') or on cocaine. ( Curran, HV; Duffin, S; Hunt, S; Mason, O; Monaghan, L; Morgan, CJ, 2012) |
| "We describe the severe lower urinary tract symptoms experienced in 6 patients with chronic recreational ketamine use." | 3.78 | Ketamine-associated urinary tract dysfunction: an underrecognized clinical entity. ( Cai, Z; Chen, Z; Guan, Z; Gui, Y; Lai, Y; Li, X; Ni, L; Wu, S; Yang, S; Ye, J, 2012) |
| "We analyzed the imaging findings in 45 patients with KAUD, all having a history of ketamine abuse and presenting with severe lower urinary tract symptoms." | 3.78 | [Imaging features of urinary dysfunction associated with ketamine abuse]. ( Gao, L; Gu, D; Huang, J; Huang, Z; Wang, Y; Wu, P; Zhao, J; Zheng, H; Zheng, S, 2012) |
| "Ketamine abusers frequently presented with upper GI symptoms, the commonest of which is epigastric pain (73% of abusers)." | 3.76 | Upper gastrointestinal problems in inhalational ketamine abusers. ( Chan, MY; Chu, SK; Fung, KW; Leung, SK; Man, CW; Poon, TL; Wong, KF; Yiu, MK, 2010) |
| "The drug ketamine is frequently abused for recreational use in Asia, but few studies in humans have focused on the effects of ketamine exposure during pregnancy on the health of neonates." | 3.76 | Infant with in utero ketamine exposure: quantitative measurement of residual dosage in hair. ( Chang, YZ; Chen, JY; Su, PH, 2010) |
| "A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse." | 3.74 | The destruction of the lower urinary tract by ketamine abuse: a new syndrome? ( Cheng, CH; Chu, PS; Chu, RW; Lau, FL; Ma, WK; Man, CW; Tse, JM; Wong, S; Wong, SC; Yiu, MK, 2008) |
| " A case of hypertension and pulmonary oedema in such a patient, possibly triggered by ketamine, is reported." | 3.68 | Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse. ( Murphy, JL, 1993) |
| "Ketamine usage can produce undesirable psychological manifestations including hallucinations and long-term psychotomimetic effects." | 3.01 | Current approaches for the treatment of ketamine-induced cystitis. ( Lehmann, C; Miab, ZR; Scott, C; Zhou, J, 2023) |
| "Drug abuse has become a public health concern." | 2.82 | Ketamine plus Alcohol: What We Know and What We Can Expect about This. ( Cartágenes, SC; Conceição, BCD; Farias, SV; Fernandes, LMP; Ferreira, VMM; Fontes-Júnior, EA; Kobayashi, NHC; Luz, DA; Machado-Ferraro, KM; Maia, CDSF; Silveira, CCMD, 2022) |
| "Ketamine is a dissociative anesthetic that is currently considered for several new indications." | 2.82 | Harm related to recreational ketamine use and its relevance for the clinical use of ketamine. A systematic review and comparison study. ( Van Amsterdam, J; Van Den Brink, W, 2022) |
| "Ketamine is a N-methyl-d-aspartate receptor antagonist used clinically as an anaesthetic, yet also abused for its euphoric and perceptual properties." | 2.76 | Oral ketamine as a positive control in human abuse potential studies. ( Romach, MK; Sellers, EM; Shram, MJ, 2011) |
| "Ketamine has previously been shown to induce delusion-like or referential beliefs, both acutely in healthy volunteers and naturalistically among nonintoxicated users of the drug." | 2.74 | Superstitious conditioning as a model of delusion formation following chronic but not acute ketamine in humans. ( Brandner, B; Curran, HV; Das, RK; Freeman, TP; Klaassen, E; Morgan, CJ; Stefanovic, A, 2009) |
| "Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that has medical indications but is also used as a recreational drug." | 2.71 | Ketamine impairs response inhibition and is positively reinforcing in healthy volunteers: a dose-response study. ( Brandner, B; Bromley, L; Curran, HV; Mofeez, A; Morgan, CJ, 2004) |
| "Ketamine is a general anesthetic." | 2.66 | What urologists need to know about ketamine-induced uropathy: A systematic review. ( Castellani, D; Dellabella, M; Gregori, A; Gubbiotti, M; Gudaru, K; Pirola, GM; Rubilotta, E, 2020) |
| "Esketamine was recently licensed by the US Food and Drug Administration (FDA) and European Drug Agency (EDA) for use in treatment resistant depression (TRD), and further research indicates ketamine as a possible treatment in other mental health conditions." | 2.66 | Ketamine as a mental health treatment: Are acute psychoactive effects associated with outcomes? A systematic review. ( Borissova, A; Curran, HV; Grabski, M; Marsh, B; Morgan, CJA, 2020) |
| "The rationale for the use of MDMA in PTSD and SUD is being extended to a broader beneficial "psychedelic effect," which is supporting further clinical investigations, in spite of the lack of mechanistic hypothesis." | 2.58 | Psychedelics and reconsolidation of traumatic and appetitive maladaptive memories: focus on cannabinoids and ketamine. ( Chiamulera, C; Fattore, L; Fumagalli, G; Piva, A; Zanda, MT, 2018) |
| "Ketamine is a dissociative anaesthetic drug which acts on the central nervous system chiefly through antagonism of the n-methyl-d-aspartate (NMDA) receptor." | 2.58 | Ketamine for the treatment of addiction: Evidence and potential mechanisms. ( Ivan Ezquerra-Romano, I; Krupitsky, E; Lawn, W; Morgan, CJA, 2018) |
| "Ketamine is an N-methyl-d-aspartate receptor antagonist, a dissociative anaesthetic agent and a treatment option for major depression, treatment-resistant depression, and bipolar disorder." | 2.58 | Management of complications of ketamine abuse: 10 years' experience in Hong Kong. ( Hong, YL; Lai, PT; Ng, CF; Tam, YH; Wong, JH; Yee, CH, 2018) |
| "Ketamine is a noncompetitive antagonist of N-methyl-d-asparate (NMDA) receptor and has been long used as an anesthetic agent in humans and veterinary medicine." | 2.53 | Ketamine abuse potential and use disorder. ( Lin, D; Liu, Y; Wu, B; Zhou, W, 2016) |
| "Ketamine was discovered in the 1960s and released for public use in 1970." | 2.53 | A REVIEW OF KETAMINE ABUSE AND DIVERSION. ( Baron, D; Esmaili, N; Gold, M; Juarez, G; Sassano-Higgins, S, 2016) |
| "R-ketamine has greater antidepressant actions than S-ketamine, without ketamine-related side-effects." | 2.53 | Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant. ( Ding, Z; Hashimoto, K; Lu, L; Shi, J; Zhang, Y; Zhu, W, 2016) |
| "Ketamine is a dissociative anesthetic." | 2.52 | Effects of ketamine on psychomotor, sensory and cognitive functions relevant for driving ability. ( Giorgetti, R; Marcotulli, D; Schifano, F; Tagliabracci, A, 2015) |
| "Ketamine is a dissociative anesthetic and substance of abuse." | 2.50 | Ketamine: an update on its abuse. ( Anderson, PD; Bokor, G, 2014) |
| " After long-term use as a dissociative anesthetic, it has re-emerged as a useful agent for ameliorating pain, asthmaticus, and depression." | 2.50 | Ketamine-an update on its clinical uses and abuses. ( Lei, H; Xu, J, 2014) |
| "Ketamine is a relatively new recreational drug used by youngsters in recent decades." | 2.49 | Genitourinary toxicity of ketamine. ( Guo, Q; Liang, BL; Wei, YB; Yang, JR; Yin, Z; Zhou, KQ, 2013) |
| "Urological toxicity, hepatotoxicity and cognitive deficits are all reported as adverse effects of the recreational use of ketamine." | 2.48 | Ketamine for chronic noncancer pain: concerns regarding toxicity. ( Bell, RF, 2012) |
| "Problematic compounds may cause seizures either acutely or on withdrawal: Their use may reduce effectiveness of antiepileptic drugs, or may simply promote and enhance chaotic lifestyles." | 2.48 | Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention. ( Borland, W; Leach, JP; Mohanraj, R, 2012) |
| "Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances." | 2.48 | The role of setting for ketamine abuse: clinical and preclinical evidence. ( Badiani, A; De Luca, MT; Meringolo, M; Spagnolo, PA, 2012) |
| "It is reported to cause lower urinary tract symptoms (LUTS), and published accounts of its deleterious effects are increasing." | 2.47 | Ketamine-induced vesicopathy: a literature review. ( Middela, S; Pearce, I, 2011) |
| "Ketamine has become increasingly recognized as a drug of recreational use." | 2.47 | Recreational ketamine: from pleasure to pain. ( Baker, SC; Cottrell, A; Fulford, S; Gillatt, D; Harris, M; Southgate, J; Wood, D; Woodhouse, C, 2011) |
| "Ketamine is a phencyclidine derivative acting primarily as a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) excitatory glutamate receptors." | 2.45 | [Advances in research of ketamine addiction mechanism]. ( Bian, SZ; Gu, ZL; Jiang, XG; Liu, WL; Qin, ZH, 2009) |
| "Ketamine is a noncompetitive NMDA receptor antagonist and comes into being a new problem of drug abuse." | 2.44 | [A reviewing for abusing of ketamine]. ( Bian, SZ; Yang, J, 2007) |
| "Ketamine is a new party drug, which is easy to obtain." | 2.44 | [Ketamine as a party drug]. ( Kramers, C; van Dongen, RT; Vantroyen, B; Vroegop, MP, 2007) |
| "The number of registered drug abusers increased from 70,000 in 1990 to more than one million by the end of 2004." | 2.43 | Recent trends in drug abuse in China. ( Fang, YX; Liu, ZM; Lu, L; Shi, J; Wang, YB, 2006) |
| "Ketamine has a complex mechanism of action that is further complicated by stereoselectivity; however, antagonism of glutamate NDMA receptors is thought to underlie its analgesic, dissociative and neuroprotective effects." | 2.43 | Ketamine : from medicine to misuse. ( Winstock, AR; Wolff, K, 2006) |
| "Drug abuse affects a significant number of individuals of all ages." | 2.42 | Common drugs of abuse--Part II. ( Cuddy, ML, 2004) |
| "This article summarizes the short-term physiological toxicity and the adverse behavioral effects of four substances (GHB, ketamine, MDMA, and Rohypnol) that have been used at latenight dance clubs." | 2.42 | Acute toxic effects of club drugs. ( Gable, RS, 2004) |
| "Ketamine is an anaesthetic used in human medicine and veterinary practice, synthesised on 1962 and marketed on 1970 in France." | 2.41 | [Ketamine--dreams and realities]. ( Arditti, J; Bourdon, JH; Brun, A; de Haro, L; Spadari, M; Valli, M, 2002) |
| "Flunitrazepam is a potent benzodiazepine." | 2.41 | Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate. ( Larive, LL; Romanelli, F; Smith, KM, 2002) |
| "LUTS (Interstitial Cystitis Symptom Index [ICSI] + Interstitial Cystitis Problem Index [ICPI] ≥12) was found to be a significant risk factor for FSD in KAs." | 1.91 | Relationship between sexual and bladder dysfunction in women consuming ketamine. ( Chang, SJ; Jong, BE; Li, CH; Yang, SS, 2023) |
| "Illicit substance use has constantly evolved over the years, particularly in the party scene." | 1.91 | First results of the French OCTOPUS survey among festival attendees: a latent class analysis. ( Babonnaud, L; Bresdin, V; Eudeline, V; Grall-Bronnec, M; Guillet, JE; Guillo, M; Istvan, M; Jolliet, P; Laigo, P; Mainguy, M; Schreck, B; Victorri-Vigneau, C, 2023) |
| "Hydronephrosis was present in 20 (24." | 1.91 | Ketamine uropathy: Clinical experience in a high prevalence center. ( Beckley, I; Downey, A; Shepherd, R; Sturgess, G, 2023) |
| "In Hong Kong, all types of drug use disorders appear to be significantly associated with increased risk of self-harm or suicide, but risk levels vary by type of drug use disorder." | 1.72 | Risk of self-harm or suicide associated with specific drug use disorders, 2004-2016: a population-based cohort study. ( Chai, Y; Chan, EW; Chan, SKW; Luo, H; Man, KKC; Wei, Y; Wong, ICK; Yip, PSF, 2022) |
| "Multiple illicit substance users were more likely to use methamphetamine (p = 0." | 1.72 | Survey of substance use among adolescent drug offenders referred from juvenile courts in Taiwan: Clinical epidemiology of single versus multiple illicit substance use. ( Chen, LY; Chen, MH; Chen, YH; Wei, HT, 2022) |
| "A 37-year-old man with a history of drug abuse was discovered with several bags labeled as research chemicals around him and traces of powder on his nose." | 1.72 | New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking. ( Couette, A; Ferron, PJ; Gicquel, T; Grandin, L; Le Daré, B; Morel, I; Pelletier, R, 2022) |
| "Ketamine is a dissociative anesthetic used in medical practice, used recreationally since the mid-1960s." | 1.62 | Ketamine Use Among People Who Regularly Use Ecstasy and Other Illicit Stimulants in Australia: Trends and Characteristics of Use, 2009-2019. ( Cossar, R; Dietze, P; Djordjevic, F; Lenton, S; Peacock, A; Salom, C; Stewart, AC, 2021) |
| "Ketamine is a dissociative anesthetic used in veterinary and human medicine since the 1970s." | 1.62 | Increasing Prevalence of Ketamine in Drivers in New York City Including the Identification of 2-Fluoro-Deschloroketamine. ( Arango, E; Cooper, G; Rosario, Z; Toriello, A, 2021) |
| "Ketamine is a phencyclidine derivative with dissociative anaesthetic properties." | 1.62 | Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997-2019. ( Claridge, H; Copeland, CS; Corkery, JM; Goodair, C; Hung, WC; Schifano, F, 2021) |
| "Ketamine has remained the most commonly used illicit drug among adolescents in Taiwan." | 1.62 | Appetitive Motivation and Regulatory Processes in Adolescent Ketamine Users. ( Chang, HH; Ho, MC; Huang, CL, 2021) |
| "We examined the association of lower urinary tract symptoms and levels of Nectin-4, a member of the cell adhesion molecules that is essential for maintaining the urothelium barrier in chronic ketamine abusers." | 1.62 | Increased Nectin-4 levels in chronic ketamine abusers and the relationship with lower urinary tract symptoms. ( Chang, HM; Chen, PY; Fang, CP; Hsu, YC; Huang, MC; Kuo, HW; Liu, TH; Liu, YL; Wu, CT, 2021) |
| "Ketamine is a dissociative anesthetic first developed in the 1960s but is increasingly used at subanesthetic doses for both clinical and non-clinical purposes." | 1.56 | Ketamine sensitization: Influence of dose, environment, social isolation and treatment interval. ( Heller, CY; Trujillo, KA, 2020) |
| "Studies on the mortalities of drug abusers in China are scarce." | 1.56 | Mortalities of methamphetamine, opioid, and ketamine abusers in Shanghai and Wuhan, China. ( Li, F; Liu, J; Liu, S; Lu, X; Yip, PSF, 2020) |
| "The treatment of ketamine users is substantially challenged by high dropout rates, raising questions regarding contributing factors." | 1.56 | Cognitive impairment in chronic ketamine abusers. ( Hao, W; Tang, WK; Xu, Y; Zhang, B; Zhang, C, 2020) |
| "Ketamine users were categorized as adolescent-onset and adult-onset based on when they were first exposed to ketamine." | 1.56 | Effects of early ketamine exposure on cerebral gray matter volume and functional connectivity. ( Chen, CM; Chou, CY; Duann, JR; Huang, CC; Hung, CC; Lee, TS; Li, CR; Lin, CP; Liu, YH, 2020) |
| "Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems." | 1.56 | Sleep quality among individuals with ketamine use and the mediating role of craving. ( Hsu, CY; Ko, CH; Lin, HC; Wang, PW; Wu, HC; Yen, CF, 2020) |
| "Ketamine is known to cause urinary tract dysfunction." | 1.51 | Substance abuse effects on urinary tract: methamphetamine and ketamine. ( Hong, YL; Lai, PT; Ng, CF; Tam, YH; Yee, CH, 2019) |
| "Ketamine abuse causes cognitive impairments, which negatively impact on users' abstinence, prognosis, and quality of life." | 1.48 | Other drug use does not impact cognitive impairments in chronic ketamine users. ( Liang, HJ; Lin, SK; Tang, WK; Ungvari, GS; Zhang, C, 2018) |
| "Ketamine has emerged as a major substance of abuse worldwide and has been listed with methamphetamine (METH) as two of the most widely available illicit substances in Taiwan." | 1.48 | Cognitive profile of ketamine-dependent patients compared with methamphetamine-dependent patients and healthy controls. ( Chen, CK; Chen, YC; Huang, MC; Lin, SK; Wang, LJ; Xu, K, 2018) |
| "Chronic ketamine users had cognitive impairments across multiple domains." | 1.48 | The profile of cognitive impairments in chronic ketamine users. ( Deng, X; Ding, Y; Fan, N; He, H; Ke, X; Liu, Y; Ning, Y; Wang, D; Xu, K; Zhang, X; Zhou, C; Zhou, Y, 2018) |
| "Ketamine abuse has become a global phenomenon in recent years." | 1.46 | Clinical Outcome of Augmentation Enterocystoplasty for Patients with Ketamine-induced Cystitis. ( Jhang, JF; Kuo, HC; Lee, YK, 2017) |
| "Ketamine is a recreational drug widely abused in East Asia and also in certain subpopulations of the United States." | 1.46 | Ketamine Abuse Syndrome: Hepatobiliary and Urinary Pathology Among Adolescents in Flushing, NY. ( Gordon, L; Kivovich, V; Wang, JW, 2017) |
| "Treatment with carisoprodol and phenobarbital provided additional benefit and can be considered in cases of severe carisoprodol withdrawal." | 1.46 | Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. ( Benowitz, NL; Horng, H; Smollin, CG; Vo, KT, 2017) |
| " The higher ketamine use frequency and dosage were associated with more severe depressive symptoms." | 1.43 | Profiling the psychotic, depressive and anxiety symptoms in chronic ketamine users. ( Deng, X; Ding, Y; Fan, N; He, H; Ke, X; Ning, Y; Rosenheck, R; Sun, B; Tang, W; Wang, D; Xu, K; Zhou, C, 2016) |
| "In this study, 11 617 non-substance abusers were regarded as control subjects and 321 (2." | 1.43 | Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse. ( Hong, YL; Lai, PT; Lee, WM; Ng, CF; Pang, KK; Tam, YH; Wong, YS, 2016) |
| "Ketamine has been reported to impair human cognitive function as a recreational drug of abuse." | 1.43 | Changes in hippocampal AMPA receptors and cognitive impairments in chronic ketamine addiction models: another understanding of ketamine CNS toxicity. ( Cui, W; Ding, R; Du, A; He, B; Li, L; Li, Y; Lu, Y; Shen, R; Wu, X; Yu, H; Zhang, G; Zhou, J, 2016) |
| "Ketamine is a powerful anesthetic drug used in both human and veterinary surgery, but it is also commonly misused because of its psychotropic properties." | 1.42 | Cut-off proposal for the detection of ketamine in hair. ( Di Corcia, D; Diana, P; Gerace, E; Malvaso, V; Romeo, M; Salomone, A; Vincenti, M, 2015) |
| "Ketamine was used as a reference drug." | 1.42 | Methoxetamine, a ketamine derivative, produced conditioned place preference and was self-administered by rats: Evidence of its abuse potential. ( Botanas, CJ; Cheong, JH; de la Peña, JB; Dela Peña, IJ; Jang, CG; Kim, HJ; Lee, YS; Tampus, R; Yoon, R, 2015) |
| "Ketamine is a short-acting anaesthetic agent that has gained popularity as a 'club drug' due to its hallucinogenic effects." | 1.42 | The clinical presentation and diagnosis of ketamine-associated urinary tract dysfunction in Singapore. ( Aydin, H; Kuo, T; Ng, LG; Sundaram, P; Yek, J, 2015) |
| "Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that has been found to induce schizophrenia-type symptoms in humans and is a potent and fast-acting antidepressant." | 1.40 | Abnormalities in white matter microstructure associated with chronic ketamine use. ( Curran, HV; Edward Roberts, R; Friston, KJ; Morgan, CJ, 2014) |
| " Chronic use has been suggested to lead to persistent schizophrenia-like neurobiological changes." | 1.40 | Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users. ( Fam, J; Furby, H; Howes, OD; Hughes, E; Morgan, C; Pepper, F; Stone, JM, 2014) |
| "Four patients (14." | 1.40 | Evaluation of the extent of ketamine-induced uropathy: the role of CT urography. ( Chang, CY; Huang, LK; Lin, AT; Shen, SH; Wang, JH, 2014) |
| " The second experiment examined effects of repeated dosing with ketamine (3." | 1.40 | Dissociable effects of the noncompetitive NMDA receptor antagonists ketamine and MK-801 on intracranial self-stimulation in rats. ( Hillhouse, TM; Negus, SS; Porter, JH, 2014) |
| "Methamphetamine (4mg/kg)-induced place preference mice model was successfully established; ketamine (15mg/kg), rhynchophylline (40mg/kg) and rhynchophylline (80mg/kg) can eliminate place preference; Immunohistochemistry showed that the number of NR2B-positive neurons in hippocampus was increased in the methamphetamine model group, whereas less NR2B-positive neurons were found in the ketamine group, low and high dosage rhynchophylline group." | 1.40 | Effect of rhynchophylline on conditioned place preference on expression of NR2B in methamphetamine-dependent mice. ( Fang, M; Guo, Y; Jiang, M; Li, J; Liu, W; Liu, Y; Luo, C; Mo, Z; Peng, Q, 2014) |
| "Recent substance abuse research indicates gender differences in the substance-related epidemiology, biological responses, progression to dependence, medical consequences and treatments." | 1.40 | Gender differences in subjective discontinuation symptoms associated with ketamine use. ( Chen, WY; Huang, MC; Lin, SK, 2014) |
| "A notice posted on the website invited substance users to participate in a web-based survey on "drug use and health"." | 1.39 | Ketamine is associated with lower urinary tract signs and symptoms. ( Baggott, MJ; Balt, S; Erowid, E; Erowid, F; Galloway, GP; Mendelson, J; Pal, R, 2013) |
| "Ketamine abuse may cause variable urinary tract injury." | 1.39 | Renal infarction secondary to ketamine abuse. ( Cha, TL; Chen, CL; Chen, JL; Meng, E; Tang, SH; Tsao, CW; Wu, ST, 2013) |
| "Eighty-four subjects recruited from substance abuse clinics and non-governmental counseling services catering for ketamine abusers were examined by one or two TCM practitioners." | 1.39 | Traditional Chinese medicine diagnoses in persons with ketamine abuse. ( Chan, T; Lam, M; Leung, W; Sun, W; Tang, W; Ungvari, GS, 2013) |
| "Ketamine users are often poly-substance users." | 1.39 | Cognitive impairments in poly-drug ketamine users. ( Chan, F; Lau, CG; Liang, HJ; Tang, A; Tang, WK; Ungvari, GS, 2013) |
| "• Both the Interstitial Cystitis Symptom Index and Interstitial Cystitis Problem Index scores were significantly higher in patients with KC compared to controls (P < 0." | 1.38 | Sexual dysfunction in women with ketamine cystitis: a case-control study. ( Chuang, SM; Huang, CH; Jang, MY; Juan, YS; Lin, HY; Long, CY; Wu, WJ, 2012) |
| "Ketamine has been the commonest abusive substance used by Hong Kong teenager since 2005." | 1.38 | Acute and chronic toxicity pattern in ketamine abusers in Hong Kong. ( Yiu-Cheung, C, 2012) |
| "Ketamine is a non-competitive anatognist of the N-methyl-D-aspartate (NMDA) receptor commonly used as an anesthetic and analgesic." | 1.38 | Alterations in regional homogeneity of resting-state brain activity in ketamine addicts. ( Chen, H; Chen, X; Fornito, A; Hao, W; Liao, Y; Liu, T; Tang, J; Wang, X; Xiang, X, 2012) |
| "Ketamine is a non-competitive antagonist of N-methyl-d-aspartate receptor, which plays important roles in synaptic plasticity and neuronal learning." | 1.37 | Permanent deficits in brain functions caused by long-term ketamine treatment in mice. ( Lam, LH; Lam, WP; Mak, YT; Pan, F; Sun, L; Tang, HC; Wai, MS; Wong, YW; Yew, DT, 2011) |
| "Ketamine is a non-competitive N-methyl-D: -aspartate (NMDA) receptor antagonist which interferes with the action of excitatory amino acids (EAAs) including glutamate and aspartate." | 1.37 | Chronic ketamine use increases serum levels of brain-derived neurotrophic factor. ( Angelucci, F; Bria, P; Caltagirone, C; Gelfo, F; Martinotti, G; Ricci, V; Tonioni, F, 2011) |
| "The growing social problem of drug abuse has increased the likelihood that anesthesiologists will find acute or chronic drug users among patients requiring anesthesia for elective or emergency surgery." | 1.37 | [Anesthesia in drug addiction]. ( Uña Orejón, R; Vázquez Moyano, M, 2011) |
| "Ketamine is a dissociative anaesthetic agent that is still widely used in veterinary and human medicine." | 1.37 | Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series. ( Austin, AS; Freeman, JG; Krishnamoorthy, R; Lo, RS, 2011) |
| "Ketamine is a unique anaesthetic because it has both hypnotic and analgesic effects and also potential hallucinogenic side effects." | 1.37 | [Ketamine is used again by both physicians and addicts]. ( Barnung, S; Rasmussen, LS; Sørensen, AG, 2011) |
| "Ketamine was developed in the early 1960s as an anesthetic and has been used for medical and veterinary procedures since then." | 1.37 | The neurobehavioral pharmacology of ketamine: implications for drug abuse, addiction, and psychiatric disorders. ( Bates, M; Garcia, C; Heller, CY; Smith, ML; Sullivan, B; Trujillo, KA, 2011) |
| " Assessments of psychological wellbeing showed greater dissociative symptoms in frequent users and a dose-response effect on delusional symptoms, with frequent users scoring higher than infrequent, abstinent users and non-users, respectively." | 1.36 | Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study. ( Curran, HV; Morgan, CJ; Muetzelfeldt, L, 2010) |
| "Ketamine abuse has been shown to have a deleterious impact on brain function." | 1.36 | Frontal white matter abnormalities following chronic ketamine use: a diffusion tensor imaging study. ( Chen, X; Fletcher, PC; Hao, W; Liao, Y; Liu, T; Ma, M; Tang, J; Wang, X; Wu, Z; Yang, M, 2010) |
| "A method of hollow fiber (HF) liquid phase microextraction (LPME) combined with gas chromatography (GC)-flame ionization detection (FID) was developed for the simultaneous quantification of trace amphetamine (AP), methamphetamine (MA), methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), caffeine and ketamine (KT) in drug abuser urine samples." | 1.36 | Simultaneous quantification of amphetamines, caffeine and ketamine in urine by hollow fiber liquid phase microextraction combined with gas chromatography-flame ionization detector. ( Chen, J; He, M; Hu, B; Xiong, J, 2010) |
| "Ketamine is a short-acting dissociative anaesthetic whose hallucinogenic side effects have led to an increase in its illicit use amongst club and party goers." | 1.36 | Ketamine-associated lower urinary tract destruction: a new radiological challenge. ( Corrigan, AG; Cottrell, AM; Gillatt, DA; Mason, K; Mitchelmore, AE, 2010) |
| "52 ketamine users were "opportunistically" recruited to take part in a survey of the psychological effects of the drug, in Manchester, United Kingdom in 2008." | 1.36 | Quantifying the psychological effects of ketamine: from euphoria to the k-Hole. ( McCoy, L; Stirling, J, 2010) |
| "5-h intervals) 12 h prior to the MDMA dosing regimen (20 mg/kg x 3 at 2-h intervals) aggravated the MDMA-induced dopaminergic toxicity." | 1.35 | Ketamine pretreatment exacerbated 3,4-methylenedioxymethamphetamine-induced central dopamine toxicity. ( Cherng, CG; Ho, MC; Ke, JJ; Tsai, CW; Tsai, YP; Yu, L, 2008) |
| "Substance abuse is a major health and social problem among Hong Kong youth and ketamine is the drug most commonly abused." | 1.35 | Dilated common bile ducts mimicking choledochal cysts in ketamine abusers. ( Cheung, YS; Lai, PB; Lee, KF; Ng, WW; Wong, J; Wong, SW, 2009) |
| "Although the dosage and duration of ketamine abuse causing severe side-effects are still unclear, some patients develop irreversible histological changes in the urinary tract." | 1.35 | Ketamine-associated bladder dysfunction. ( Cha, TL; Chang, SY; Chuang, FP; Lin, CM; Sun, GH; Tang, SH; Tsai, TH; Tsao, CW; Wu, ST; Yu, DS, 2009) |
| "Ketamine was found in 28 of these cases, signifying the popularity of this drug in Taiwan." | 1.35 | Methylenedioxymethamphetamine-related deaths in Taiwan: 2001-2008. ( Lin, DL; Liu, HC; Liu, RH, 2009) |
| "Ketamine is a potentially dependence-forming drug." | 1.35 | Attentional bias to incentive stimuli in frequent ketamine users. ( Curran, HV; Morgan, CJ; Rees, H, 2008) |
| " Addictive/dependent patterns of behaviour were also a concern: the majority of frequent users reported using the drug without stopping until supplies ran out and the mean increase in dosage in this group was six-fold from initiation to current use." | 1.35 | Journey through the K-hole: phenomenological aspects of ketamine use. ( Curran, HV; Kamboj, SK; Morgan, CJ; Muetzelfeldt, L; Rees, H; Taylor, J, 2008) |
| "Data ascertained in a study of club drug use among 450 gay and bisexual men indicate that at least one class of PDE-5 (phosphodiesterase type 5 inhibitor, sildenafil [Viagra]) is used frequently in combination with club drugs such as methamphetamine, MDMA (3,4 methylenedioxymethamphetamine [ecstasy]), ketamine, cocaine, and GHB (gamma hydroxy butyrate)." | 1.34 | Sildenafil (Viagra) and club drug use in gay and bisexual men: the role of drug combinations and context. ( Green, KA; Halkitis, PN, 2007) |
| "The correlates of polysubstance use were examined using the two-step procedure of variable selection." | 1.34 | Polysubstance use and its correlates in adolescent ecstasy users in Taiwan. ( Cheng, CP; Hsu, SY; Yen, CF, 2007) |
| "Ketamine was generally the last substance experimented with throughout their lifetime, as of the age of 22." | 1.34 | Characteristics and behaviors of ketamine users in France in 2003. ( Akoka, S; Bello, PY; Reynaud-Maurupt, C; Toufik, A, 2007) |
| "Levels of dissociation were also higher in ketamine users only on the night of drug use." | 1.34 | Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later. ( Curran, HV; Millard, I; Morgan, CJ; Muetzelfeldt, L; Uhlhaas, PJ, 2007) |
| "Ketamine is a noncompetitive antagonist at the glutamatergic N-methyl-D-aspartate (NMDA) receptor that is used in human and animal medicine as an injectable anesthetic." | 1.33 | Altered prefrontal dopaminergic function in chronic recreational ketamine users. ( Abi-Dargham, A; Cooper, TB; Frankle, WG; Gil, R; Huang, Y; Hwang, DR; Keefe, R; Kegeles, LS; Khenissi, L; Laruelle, M; Martinez, D; Narendran, R; Slifstein, M; Talbot, PS, 2005) |
| "Ketamine users were primarily employed youths." | 1.33 | Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths. ( Galvin, DM; Schlenger, WE; Wu, LT, 2006) |
| "Ketamine could suppress not only the place preference but also the phosphorylation of CREB produced by morphine, F9202 and F9204." | 1.32 | Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm. ( Che, LW; Chen, J; Chi, ZQ; Gao, C; Xu, XJ, 2003) |
| "Here, we report the patterns of drug abuse by the participants in a metropolitan city disco-dancing club and the general public in Taiwan." | 1.32 | Profiles of urine samples from participants at rave party in Taiwan: prevalence of ketamine and MDMA abuse. ( Hu, AR; Lin, HR; Lua, AC; Tseng, YT; Yeh, PC, 2003) |
| "Odds ratios (ORs) for association of substance use and UAI during the previous year were adjusted for age and calendar year." | 1.32 | Unprotected anal intercourse associated with recreational drug use among young men who have sex with men depends on partner type and intercourse role. ( Hogg, RS; Lampinen, TM; Rusch, M; Schilder, A, 2004) |
| "Ketamine is a dissociative anaesthetic that is also a drug of abuse." | 1.32 | Beyond the K-hole: a 3-year longitudinal investigation of the cognitive and subjective effects of ketamine in recreational users who have substantially reduced their use of the drug. ( Curran, HV; Monaghan, L; Morgan, CJ, 2004) |
| "Ketamine was used for anaesthesia originally but has emerged as an abused drug in recent years." | 1.32 | In-tube solid-phase microextraction with poly(methacrylic acid-ethylene glycol dimethacrylate) monolithic capillary for direct high-performance liquid chromatographic determination of ketamine in urine samples. ( Da, SL; Fan, Y; Feng, YQ; Gao, XP, 2004) |
| "Tachycardia was the most common physical examination finding." | 1.31 | Ketamine abusers presenting to the emergency department: a case series. ( Bayer, MJ; McKay, CA; Vieira, L; Weiner, AL, 2000) |
| "Ketamine is an anaesthetic agent primarily used in veterinary medicine and paediatrics." | 1.31 | [New drugs at "rave parties": ketamine and prolintane]. ( Canal, M; Gaulier, JM; Lachâtre, G; Marquet, P; Pradeille, JL, 2002) |
| "Ketamine hydrochloride is a safe and rapid-acting non-opioid, lipid soluble anaesthetic with a short elimination half-life that is used for medical and veterinary purposes." | 1.31 | Ketamine dependence. ( Berry, N; Kumar, R; Pal, HR; Ray, R, 2002) |
| " It is thus of interest to examine the consequences, if any, of chronic use in humans." | 1.28 | Ketamine--can chronic use impair memory? ( Jansen, KL, 1990) |
| " Generally, an orderly inverted U-shaped dose-response curve for rates of self-injection has been observed." | 1.27 | Animal models of intravenous phencyclinoid self-administration. ( Marquis, KL; Moreton, JE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (5.16) | 18.7374 |
| 1990's | 8 (1.88) | 18.2507 |
| 2000's | 96 (22.54) | 29.6817 |
| 2010's | 224 (52.58) | 24.3611 |
| 2020's | 76 (17.84) | 2.80 |
| Authors | Studies |
|---|---|
| Solano, JJ | 1 |
| Clayton, LM | 1 |
| Parks, DJ | 1 |
| Polley, SE | 1 |
| Hughes, PG | 1 |
| Hennekens, CH | 1 |
| Shih, RD | 1 |
| Alter, SM | 1 |
| Fitzgerald, ND | 3 |
| Striley, CW | 1 |
| Palamar, JJ | 11 |
| Copeland, J | 3 |
| Kurtz, S | 1 |
| Cottler, LB | 5 |
| Rutherford, C | 2 |
| Keyes, KM | 1 |
| Kutscher, E | 1 |
| Greene, RE | 1 |
| Wong, GF | 1 |
| Lee, WM | 2 |
| Li, CK | 1 |
| Lee, TS | 4 |
| Liu, YH | 2 |
| Huang, YJ | 1 |
| Tang, WK | 8 |
| Wang, Y | 3 |
| Hu, S | 1 |
| Lin, CP | 3 |
| Li, CR | 3 |
| Hung, CC | 4 |
| Kumar, S | 1 |
| Yang, KH | 1 |
| Han, BH | 1 |
| Chai, Y | 1 |
| Luo, H | 1 |
| Wei, Y | 3 |
| Chan, SKW | 1 |
| Man, KKC | 1 |
| Yip, PSF | 2 |
| Wong, ICK | 1 |
| Chan, EW | 1 |
| Li, X | 4 |
| Feng, L | 1 |
| Fan, X | 1 |
| Huang, J | 4 |
| Du, Y | 1 |
| Chen, YH | 1 |
| Chen, MH | 1 |
| Wei, HT | 1 |
| Chen, LY | 5 |
| Varì, MR | 1 |
| Ricci, G | 1 |
| Cavallo, M | 1 |
| Pichini, S | 1 |
| Sirignano, A | 1 |
| Graziano, S | 1 |
| Revol, B | 1 |
| Lapeyre-Mestre, M | 2 |
| Fouilhé Sam-Laï, N | 1 |
| Jouanjus, E | 2 |
| Yu, WJ | 1 |
| Cottler, L | 1 |
| Li, JH | 3 |
| Henningfield, J | 1 |
| Gauvin, D | 1 |
| Bifari, F | 1 |
| Fant, R | 1 |
| Shram, M | 1 |
| Buchhalter, A | 1 |
| Ashworth, J | 1 |
| Lanier, R | 1 |
| Pappagallo, M | 1 |
| Inturrisi, C | 1 |
| Folli, F | 1 |
| Traversa, S | 1 |
| Manfredi, PL | 1 |
| Kobayashi, NHC | 1 |
| Farias, SV | 1 |
| Luz, DA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II, Randomised, Double-blind, Placebo- Controlled, Multi-site, Parallel Group Clinical Trial to Examine Ketamine as a Pharmacological Treatment for Alcohol Dependence in an Alcohol Dependent Population[NCT02649231] | Phase 2 | 96 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Effect of Intravenous Low-dose Esketamine on Maternal Depression at 2 Years After Childbirth in Women With Prenatal Depression: 2-year Follow-up of a Randomized Controlled Trial[NCT05698394] | Phase 4 | 364 participants (Actual) | Interventional | 2020-06-19 | Active, not recruiting | ||
| Phenomenological Explorations of the Esketamine-Induced Transient Dissociative State[NCT06133309] | 15 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | |||
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| A Study to Evaluate Clinical Benefits and Drawbacks of Antiretroviral Drugs as Pre-exposure Prophylaxis to Prevent HIV Infection Under Real-life Conditions Among Persons Who Pursue High-risk Sexual Practices: The Seville HIV PrEP Cohort[NCT05492565] | 500 participants (Anticipated) | Observational [Patient Registry] | 2020-01-01 | Enrolling by invitation | |||
| Using the Behaviour Change Technique Taxonomy v1 to Conceptualize the Clinical Content of a Preliminary Randomised Controlled Study of an Online Mindfulness-based Cognitive Intervention for Chemsex[NCT05929040] | 29 participants (Actual) | Interventional | 2022-03-05 | Completed | |||
| Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain: an Observational Prospective Study[NCT04123652] | Phase 4 | 162 participants (Actual) | Interventional | 2017-11-05 | Completed | ||
| A Safe Ketamine-Based Therapy for Treatment Resistant Depression[NCT01179009] | 20 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures. Timmons Z MD, Feudale B MD Children Presenting to the ED With Distal Forearm Extremity Fractures Often Require Re-alignment Under Conscious Sedation. T[NCT03466242] | Early Phase 1 | 40 participants (Anticipated) | Interventional | 2018-05-01 | Not yet recruiting | ||
| Intravesical Injection of Dextrose to Improve Lower Urinary Tract Symptoms Caused by Chronic Cystitis[NCT04821882] | 29 participants (Actual) | Interventional | 2019-05-01 | Completed | |||
| Prospective Longitudinal Study on the Treatment Outcomes of Various Treatment Modalities Under a Standardized Treatment Protocol in Patients Suffered Substance Abuse Related Voiding Dysfunction[NCT03913819] | 1,000 participants (Anticipated) | Observational | 2011-12-10 | Recruiting | |||
| A Randomized, Double-Blind, Double-Dummy, Placebo- and Active-Controlled Crossover Study to Evaluate the Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users[NCT00828659] | Phase 1 | 35 participants (Anticipated) | Interventional | 2008-12-31 | Completed | ||
| Evaluation of the Antidepressant Effects of Nitrous Oxide in People With Major Depressive Disorder[NCT05357040] | Phase 2 | 172 participants (Anticipated) | Interventional | 2021-06-30 | Recruiting | ||
| Effects of Low-dose Dexmedetomidine-esketamine Combined Nasal Administration at Night on Perioperative Sleep Quality in Breast Cancer Patients: a Randomized, Double-blind, Placebo-controlled Trial[NCT05732064] | Phase 4 | 180 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Time line follow back (NCT02649231)
Timeframe: 6 months
| Intervention | percentage of days abstinent (Mean) |
|---|---|
| Ketamine+Psychological Therapy | 86.4 |
| Ketamine+Education | 82.5 |
| Placebo+Psychological Therapy | 78.3 |
| Placebo+Education | 70.7 |
Time line follow back (NCT02649231)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine+Psychological Therapy | 13 |
| Ketamine+Education | 15 |
| Placebo+Psychological Therapy | 14 |
| Placebo+Education | 18 |
The Montgomery-Asberg Depression Rating Scale (MADRS) is a 10-item scale that measures the severity of depression, with a higher score indicating a higher level of depression. The range of scores is 0 to 60. (NCT01179009)
Timeframe: 8 weeks
| Intervention | Scores on a scale (Mean) |
|---|---|
| Ketamine 100-hour Infusion | -9.0 |
| Ketamine 40-minute Infusion | -6.4 |
74 reviews available for ketamine and Chemical Dependence
| Article | Year |
|---|---|
Ketamine plus Alcohol: What We Know and What We Can Expect about This.
Topics: Ethanol; Humans; Ketamine; Substance-Related Disorders | 2022 |
Current approaches for the treatment of ketamine-induced cystitis.
Topics: Administration, Intravesical; Animals; Cystitis; Ketamine; Substance-Related Disorders | 2023 |
No time to lose: the current state of research in rapid-acting psychotherapeutics.
Topics: Humans; Ketamine; Psychotropic Drugs; Substance-Related Disorders | 2024 |
[Neurotrophic mechanisms of psychedelic therapy].
Topics: Animals; Hallucinogens; Humans; Ibogaine; Ketamine; Mental Disorders; Nerve Growth Factors; Psychiat | 2019 |
Overlap in the neural circuitry and molecular mechanisms underlying ketamine abuse and its use as an antidepressant.
Topics: Antidepressive Agents; Brain; Cholinergic Neurons; Depressive Disorder, Major; Depressive Disorder, | 2020 |
What urologists need to know about ketamine-induced uropathy: A systematic review.
Topics: Analgesics; Cystitis; Cystoscopy; Diagnosis, Differential; Humans; Ketamine; Substance-Related Disor | 2020 |
Ketamine as a mental health treatment: Are acute psychoactive effects associated with outcomes? A systematic review.
Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; | 2020 |
Violence against women and drug-facilitated sexual assault (DFSA): A review of the main drugs.
Topics: Adjuvants, Anesthesia; Alcohol Drinking; Anesthetics, Dissociative; Benzodiazepines; Crime Victims; | 2020 |
Use and abuse of dissociative and psychedelic drugs in adolescence.
Topics: Adolescent; Adult; Age Factors; Animals; Dextromethorphan; Female; Hallucinogens; Humans; Ketamine; | 2021 |
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
Topics: Antidepressive Agents; Delivery of Health Care; Depressive Disorder, Major; Depressive Disorder, Tre | 2021 |
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
Topics: Antidepressive Agents; Delivery of Health Care; Depressive Disorder, Major; Depressive Disorder, Tre | 2021 |
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
Topics: Antidepressive Agents; Delivery of Health Care; Depressive Disorder, Major; Depressive Disorder, Tre | 2021 |
Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.
Topics: Antidepressive Agents; Delivery of Health Care; Depressive Disorder, Major; Depressive Disorder, Tre | 2021 |
[History of Ketamine: An ancient molecule that is still popular today].
Topics: Anesthetics, Dissociative; History, 20th Century; History, 21st Century; Humans; Ketamine; Stereoiso | 2022 |
Harm related to recreational ketamine use and its relevance for the clinical use of ketamine. A systematic review and comparison study.
Topics: Anesthetics, Dissociative; Dose-Response Relationship, Drug; Humans; Ketamine; Substance-Related Dis | 2022 |
Excited Delirium: A Systematic Review.
Topics: Antipsychotic Agents; Delirium; Female; Humans; Ketamine; Male; Psychomotor Agitation; Retrospective | 2018 |
Psychedelics and reconsolidation of traumatic and appetitive maladaptive memories: focus on cannabinoids and ketamine.
Topics: Anesthetics, Dissociative; Animals; Appetitive Behavior; Cannabinoids; Emotions; Hallucinogens; Huma | 2018 |
Ketamine for the treatment of addiction: Evidence and potential mechanisms.
Topics: Animals; Behavior, Addictive; Humans; Ketamine; Psychotropic Drugs; Substance-Related Disorders | 2018 |
Management of complications of ketamine abuse: 10 years' experience in Hong Kong.
Topics: Gastrointestinal Diseases; Humans; Ketamine; Substance-Related Disorders; Urologic Diseases | 2018 |
Chemsex behaviours among men who have sex with men: A systematic review of the literature.
Topics: 4-Butyrolactone; Cocaine; HIV Infections; Homosexuality, Male; Humans; Illicit Drugs; Ketamine; Male | 2019 |
Chemsex behaviours among men who have sex with men: A systematic review of the literature.
Topics: 4-Butyrolactone; Cocaine; HIV Infections; Homosexuality, Male; Humans; Illicit Drugs; Ketamine; Male | 2019 |
Chemsex behaviours among men who have sex with men: A systematic review of the literature.
Topics: 4-Butyrolactone; Cocaine; HIV Infections; Homosexuality, Male; Humans; Illicit Drugs; Ketamine; Male | 2019 |
Chemsex behaviours among men who have sex with men: A systematic review of the literature.
Topics: 4-Butyrolactone; Cocaine; HIV Infections; Homosexuality, Male; Humans; Illicit Drugs; Ketamine; Male | 2019 |
Beyond evidence-based treatment of bipolar disorder: Rational pragmatic approaches to management.
Topics: Ankyrins; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disord | 2019 |
From "Special K" to "Special M": the evolution of the recreational use of ketamine and methoxetamine.
Topics: Cyclohexanones; Cyclohexylamines; Humans; Illicit Drugs; Ketamine; Substance-Related Disorders | 2013 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Ketamine for chronic pain: risks and benefits.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Chronic Pain; Drug Monitoring; Humans; Ketamine; Neu | 2014 |
Genitourinary toxicity of ketamine.
Topics: Anesthetics, Dissociative; Animals; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; S | 2013 |
[Diagnosis and treatment of ketamine-associated cystitis: a report of 3 cases and literature review].
Topics: Biopsy; Cystitis; Cystoscopy; Humans; Ketamine; Lower Urinary Tract Symptoms; Recurrence; Retrospect | 2013 |
[Bladder pain and urinary tract symptoms as a consequence of ketamine abuse].
Topics: Analgesics; Hallucinogens; Hematuria; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; | 2014 |
Ketamine: an update on its abuse.
Topics: Gastrointestinal Diseases; Humans; Ketamine; Mental Disorders; Substance-Related Disorders; Urologic | 2014 |
Methoxetamine--a novel recreational drug with potent hallucinogenic properties.
Topics: Cyclohexanones; Cyclohexylamines; Hallucinogens; Humans; Illicit Drugs; Ketamine; Substance-Related | 2014 |
Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans.
Topics: Excitatory Amino Acid Antagonists; Gene Expression Regulation; Genetic Predisposition to Disease; Hu | 2015 |
Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders?
Topics: Animals; Antidepressive Agents; Drug Discovery; Excitatory Amino Acid Antagonists; Glutamic Acid; Hu | 2015 |
Ketamine-an update on its clinical uses and abuses.
Topics: Analgesics; Animals; Asthma; Depressive Disorder, Major; Gastrointestinal Tract; Humans; Ketamine; P | 2014 |
Effects of ketamine on psychomotor, sensory and cognitive functions relevant for driving ability.
Topics: Anesthetics, Dissociative; Attention; Cognition Disorders; Dissociative Disorders; Driving Under the | 2015 |
"Addicted to Euphoria": The History, Clinical Presentation, and Management of Party Drug Misuse.
Topics: Euphoria; History, 20th Century; Humans; Hydroxybutyrates; Illicit Drugs; Ketamine; N-Methyl-3,4-met | 2015 |
Suicide risk assessment and intervention in people with mental illness.
Topics: Antidepressive Agents; Antipsychotic Agents; Anxiety; Cognitive Behavioral Therapy; Crisis Intervent | 2015 |
Driving under the influence of non-alcohol drugs--An update. Part II: Experimental studies.
Topics: Analgesics, Opioid; Antidepressive Agents; Benzodiazepines; Cannabis; Central Nervous System Stimula | 2016 |
Ketamine abuse potential and use disorder.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Humans; Ketamine; Reinforcement, Psychology; Social | 2016 |
Generation Z: Adolescent Xenobiotic Abuse in the 21st Century.
Topics: Adolescent; Amphetamine-Related Disorders; Cannabinoids; Central Nervous System Stimulants; Designer | 2015 |
A REVIEW OF KETAMINE ABUSE AND DIVERSION.
Topics: Anesthetics, Dissociative; Humans; Ketamine; Prescription Drug Diversion; Substance-Related Disorder | 2016 |
Illegal use patterns, side effects, and analytical methods of ketamine.
Topics: Anesthetics, Dissociative; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; | 2016 |
Ketamine: A Cause of Urinary Tract Dysfunction.
Topics: Analgesics; Cystitis; Diagnosis, Differential; Female; Humans; Ketamine; Lower Urinary Tract Symptom | 2016 |
Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant.
Topics: Animals; Antidepressive Agents; Cognition Disorders; Depressive Disorder, Major; Humans; Ketamine; S | 2016 |
[Advances in research of ketamine addiction mechanism].
Topics: Anesthetics, Dissociative; Animals; Brain; Humans; Illicit Drugs; Ketamine; Mental Disorders; Rats; | 2009 |
Emergency department presentation of ketamine abusers in Hong Kong: a review of 233 cases.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Emergency Service, Hospital; Female; Hong Kong; Humans | 2010 |
Drugs involved in drug-facilitated crimes: part I: alcohol, sedative-hypnotic drugs, gamma-hydroxybutyrate and ketamine. A review.
Topics: Alcohol Drinking; Anesthetics, Dissociative; Crime; Humans; Hypnotics and Sedatives; Ketamine; Sodiu | 2010 |
Ketamine-induced vesicopathy: a literature review.
Topics: Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; Su | 2011 |
Ketamine-induced vesicopathy: a literature review.
Topics: Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; Su | 2011 |
Ketamine-induced vesicopathy: a literature review.
Topics: Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; Su | 2011 |
Ketamine-induced vesicopathy: a literature review.
Topics: Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; Su | 2011 |
Recreational ketamine: from pleasure to pain.
Topics: Adolescent; Adult; Analgesics; Epidemiologic Methods; Humans; Illicit Drugs; Ketamine; Middle Aged; | 2011 |
Club drugs: review of the 'rave' with a note of concern for the Indian scenario.
Topics: Anesthetics, Dissociative; Anti-Anxiety Agents; Designer Drugs; Flunitrazepam; Hallucinogens; Humans | 2011 |
Ketamine use: a review.
Topics: Abdominal Pain; Acute Disease; Anesthetics, Dissociative; Animals; Behavior, Addictive; Child; Chron | 2012 |
Lower urinary tract destruction due to ketamine: a report of 4 cases and review of literature.
Topics: Adult; Anesthetics, Dissociative; China; Female; Follow-Up Studies; Humans; Ketamine; Male; Substanc | 2012 |
Ketamine-snorting associated cystitis.
Topics: Adult; Cystitis; Female; Humans; Ketamine; Male; Substance-Related Disorders; Young Adult | 2011 |
New recreational drugs and the primary care approach to patients who use them.
Topics: Alkaloids; Anesthetics, Dissociative; Anesthetics, Intravenous; Butylene Glycols; Central Nervous Sy | 2012 |
Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose.
Topics: Alcoholism; Anesthetics; Anesthetics, Dissociative; Animals; Central Nervous System Depressants; Cog | 2012 |
Phenomenon of new drugs on the Internet: the case of ketamine derivative methoxetamine.
Topics: Cyclohexanones; Cyclohexylamines; Designer Drugs; Hallucinogens; Humans; Illicit Drugs; Internationa | 2012 |
Ketamine for chronic noncancer pain: concerns regarding toxicity.
Topics: Analgesics; Chemical and Drug Induced Liver Injury; Chronic Pain; Cognition Disorders; Dose-Response | 2012 |
Recreational drug use in the Asia Pacific region: improvement in our understanding of the problem through the UNODC programmes.
Topics: Amphetamine; Analgesics, Opioid; Asia, Southeastern; Cannabis; China; Crime; Data Collection; Humans | 2012 |
Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention.
Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholism; Amphetamine-Related Disorders; Benzodiaze | 2012 |
Ketamine cystitis: an emerging diagnostic and therapeutic challenge.
Topics: Cystitis; Diagnosis, Differential; Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamin | 2012 |
The role of setting for ketamine abuse: clinical and preclinical evidence.
Topics: Animals; Clinical Trials as Topic; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug | 2012 |
The effects and consequences of selected club drugs.
Topics: Central Nervous System Stimulants; Humans; Ketamine; Methamphetamine; N-Methyl-3,4-methylenedioxyamp | 2002 |
Club drugs: is it all ecstasy?
Topics: Adolescent; Adolescent Behavior; Anxiety Disorders; Humans; Illicit Drugs; Ketamine; Methamphetamine | 2002 |
Rave drugs: pharmacological considerations.
Topics: Adolescent; Adult; Anesthesia; Dancing; Designer Drugs; Emergency Treatment; Flunitrazepam; Hallucin | 2004 |
Common drugs of abuse--Part II.
Topics: 4-Butyrolactone; Catha; Designer Drugs; Dibenzothiazepines; Diterpenes; Diterpenes, Clerodane; DOM 2 | 2004 |
Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine.
Topics: Anesthetics, Dissociative; Drug Overdose; Flunitrazepam; Hallucinogens; Humans; Ketamine; Leisure Ac | 2004 |
[Club drugs: old medicines as new party drugs].
Topics: Designer Drugs; Dextromethorphan; Humans; Hydroxybutyrates; Illicit Drugs; Ketamine; Nitrous Oxide; | 2004 |
Acute toxic effects of club drugs.
Topics: Alcohol Drinking; Animals; Behavior; Drug Interactions; Flunitrazepam; Hallucinogens; Humans; Illici | 2004 |
A brief overview of the clinical pharmacology of "club drugs".
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Dancing; Flunitrazepam; GABA Modulators; Hallucino | 2005 |
Recent trends in the use of "club drugs": an Australian review.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthetics, Dissociative; Australia; Cognition Disorders; | 2005 |
Recent trends in drug abuse in China.
Topics: China; Drug and Narcotic Control; HIV Infections; Ketamine; N-Methyl-3,4-methylenedioxyamphetamine; | 2006 |
Ketamine : from medicine to misuse.
Topics: Anesthetics, Dissociative; Animals; Humans; Ketamine; Substance-Related Disorders | 2006 |
[A reviewing for abusing of ketamine].
Topics: Anesthetics, Dissociative; Cerebral Cortex; Humans; Illicit Drugs; Ketamine; Mental Disorders; Recep | 2007 |
[Ketamine as a party drug].
Topics: Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Substance-Related Disorders | 2007 |
Ketamine.
Topics: Analgesics; Anesthetics, Dissociative; Animals; Central Nervous System; Contraindications; Dose-Resp | 2008 |
Emerging drugs of abuse in Connecticut.
Topics: Cannabis; Connecticut; Female; Humans; Incidence; Ketamine; Male; Methylphenidate; Risk Assessment; | 2000 |
It's a rave new world: rave culture and illicit drug use in the young.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Ephedrine; Flunitrazepam; Humans; Illicit Drugs; Ketamine | 2001 |
[Ketamine--dreams and realities].
Topics: Anesthetics, Dissociative; Dreams; France; Humans; Ketamine; Public Policy; Risk Factors; Self Conce | 2002 |
Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate.
Topics: Flunitrazepam; Humans; Illicit Drugs; Ketamine; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Oxyba | 2002 |
The pharmacological management of postoperative pain.
Topics: Analgesics; Anesthetics, Local; Central Nervous System; Child; Drug Therapy, Combination; Humans; Ke | 1977 |
11 trials available for ketamine and Chemical Dependence
| Article | Year |
|---|---|
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial.
Topics: Alcohol Drinking; Behavior, Addictive; Dissociative Disorders; Double-Blind Method; Female; Hallucin | 2021 |
Virtual reality-based cognitive training for drug abusers: A randomised controlled trial.
Topics: Adult; Cognitive Dysfunction; Cognitive Remediation; Excitatory Amino Acid Antagonists; Female; Foll | 2020 |
Superstitious conditioning as a model of delusion formation following chronic but not acute ketamine in humans.
Topics: Adult; Conditioning, Psychological; Delusions; Dose-Response Relationship, Drug; Double-Blind Method | 2009 |
Acute and chronic effects of ketamine on semantic priming: modeling schizophrenia?
Topics: Adolescent; Adult; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amin | 2009 |
Oral ketamine as a positive control in human abuse potential studies.
Topics: Administration, Oral; Adult; Behavior, Addictive; Cross-Over Studies; Double-Blind Method; Emotions; | 2011 |
Evaluation of the abuse potential of lorcaserin, a serotonin 2C (5-HT2C) receptor agonist, in recreational polydrug users.
Topics: Adolescent; Adult; Benzazepines; Cross-Over Studies; Double-Blind Method; Female; Humans; Illicit Dr | 2011 |
[Effects of a subanaesthetic dose of ketamine on emotional and behavioral state in healthy subjects].
Topics: Adult; Anesthetics, Dissociative; Behavior; Cognition; Cross-Over Studies; Double-Blind Method; Emot | 2003 |
Ketamine impairs response inhibition and is positively reinforcing in healthy volunteers: a dose-response study.
Topics: Adult; Analgesics; Cognition Disorders; Dose-Response Relationship, Drug; Female; Humans; Ketamine; | 2004 |
Semantic priming after ketamine acutely in healthy volunteers and following chronic self-administration in substance users.
Topics: Adult; Cognition Disorders; Dissociative Disorders; Double-Blind Method; Female; Humans; Illicit Dru | 2006 |
Intravenous ketamine therapy in a patient with a treatment-resistant major depression.
Topics: Antidepressive Agents; Depressive Disorder, Major; Drug Resistance; Excitatory Amino Acid Antagonist | 2007 |
Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis.
Topics: Adult; Attention; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Hallucinogens; Hum | 2007 |
341 other studies available for ketamine and Chemical Dependence
| Article | Year |
|---|---|
Prehospital Ketamine Administration for Excited Delirium with Illicit Substance Co-Ingestion and Subsequent Intubation in the Emergency Department.
Topics: Adolescent; Delirium; Eating; Emergency Service, Hospital; Humans; Intubation, Intratracheal; Ketami | 2021 |
Test-retest reliability and cross-cultural applicability of DSM-5 adopted diagnostic criteria for ketamine use disorders.
Topics: Cross-Cultural Comparison; Diagnostic and Statistical Manual of Mental Disorders; Humans; Ketamine; | 2021 |
Trends in Ketamine Use, Exposures, and Seizures in the United States up to 2019.
Topics: Adolescent; Adult; Analgesics; Child; Female; Humans; Ketamine; Male; Seizures; Substance-Related Di | 2021 |
Ketamine Cystitis: An Underrecognized Cause of Dysuria.
Topics: Cystitis; Dysuria; Humans; Ketamine; Substance-Related Disorders | 2022 |
Qualitative Screening of Amphetamine- and Ketamine-Type Abuse Drugs in Urine Employing Dual Mode Extraction Column by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS).
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Chromatography, Liquid; Ephedrine; Humans; Illicit Drugs | 2023 |
Clinical and behavior characteristics of individuals who used ketamine.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Impulsive Behavior; Ketamine; Lower Urin | 2022 |
Ketamine use in relation to depressive symptoms among high school seniors.
Topics: Adolescent; Depression; Humans; Ketamine; Prevalence; Schools; Substance-Related Disorders; United S | 2022 |
Risk of self-harm or suicide associated with specific drug use disorders, 2004-2016: a population-based cohort study.
Topics: Analgesics, Opioid; Child; Cohort Studies; Hallucinogens; Humans; Ketamine; Risk Factors; Self-Injur | 2022 |
Wastewater-based monitoring of 2-fluoro-deschloroketamine abuse from 2019 to 2021 in a southern Chinese province.
Topics: China; Cities; Humans; Ketamine; Substance-Related Disorders; Wastewater | 2022 |
Survey of substance use among adolescent drug offenders referred from juvenile courts in Taiwan: Clinical epidemiology of single versus multiple illicit substance use.
Topics: Adolescent; Criminals; Depressive Disorder, Major; Humans; Illicit Drugs; Ketamine; Methamphetamine; | 2022 |
Ketamine: From Prescription Anaesthetic to a New Psychoactive Substance.
Topics: Anesthetics; Central Nervous System Agents; Humans; Ketamine; Prescriptions; Seizures; Substance-Rel | 2022 |
Association between NMDAR antagonists, drug abuse and dependence: A disproportionality analysis from the WHO pharmacovigilance database.
Topics: Amantadine; Analgesics; Bayes Theorem; Dextromethorphan; Humans; Ketamine; Memantine; Pharmacovigila | 2022 |
New psychoactive substances in Taiwan: The current situation and initiative for rational scheduling.
Topics: Humans; Illicit Drugs; Ketamine; Psychotropic Drugs; Substance-Related Disorders; Taiwan | 2021 |
REL-1017 (esmethadone; D-methadone) does not cause reinforcing effect, physical dependence and withdrawal signs in Sprague Dawley rats.
Topics: Animals; Ketamine; Methadone; Morphine; Oxycodone; Rats; Rats, Sprague-Dawley; Substance-Related Dis | 2022 |
Dual action of ketamine confines addiction liability.
Topics: Animals; Dopamine; Dopaminergic Neurons; Ketamine; Mice; Neuronal Plasticity; Nucleus Accumbens; Rec | 2022 |
Pooled Urine Analysis at a Belgian Music Festival: Trends in Alcohol Consumption and Recreational Drug Use.
Topics: Alcohol Drinking; Belgium; Cocaine; Cross-Sectional Studies; Ethanol; Holidays; Humans; Illicit Drug | 2022 |
Health characteristics associated with chemsex among men who have sex with men: Results from a cross-sectional clinic survey in Norway.
Topics: Cocaine; Cross-Sectional Studies; Gonorrhea; HIV Infections; Homosexuality, Male; Humans; Ketamine; | 2022 |
Use of psychedelics in the Czech Republic: results of recent population surveys.
Topics: Adult; Cannabis; Cross-Sectional Studies; Czech Republic; Hallucinogens; Humans; Illicit Drugs; Keta | 2022 |
Characteristics of poisonings involving ketamine in the United States, 2019-2021.
Topics: Aged; Analgesics, Opioid; Benzodiazepines; Female; Humans; Ketamine; Male; Sodium Oxybate; Substance | 2023 |
Characteristics of poisonings involving ketamine in the United States, 2019-2021.
Topics: Aged; Analgesics, Opioid; Benzodiazepines; Female; Humans; Ketamine; Male; Sodium Oxybate; Substance | 2023 |
Characteristics of poisonings involving ketamine in the United States, 2019-2021.
Topics: Aged; Analgesics, Opioid; Benzodiazepines; Female; Humans; Ketamine; Male; Sodium Oxybate; Substance | 2023 |
Characteristics of poisonings involving ketamine in the United States, 2019-2021.
Topics: Aged; Analgesics, Opioid; Benzodiazepines; Female; Humans; Ketamine; Male; Sodium Oxybate; Substance | 2023 |
Ketamine misuse: an update for primary care.
Topics: Humans; Ketamine; Primary Health Care; Substance-Related Disorders | 2023 |
Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence-based prediction, expert evaluation, clinical corroboration and mechanism of action analyses.
Topics: Antidepressive Agents; Artificial Intelligence; Cocaine; Cocaine-Related Disorders; Drug Repositioni | 2023 |
Relationship between sexual and bladder dysfunction in women consuming ketamine.
Topics: Adult; Cross-Sectional Studies; Cystitis, Interstitial; Female; Humans; Ketamine; Lower Urinary Trac | 2023 |
First results of the French OCTOPUS survey among festival attendees: a latent class analysis.
Topics: Cocaine; Cross-Sectional Studies; Holidays; Humans; Ketamine; Latent Class Analysis; N-Methyl-3,4-me | 2023 |
Adverse drug effects as a deterrent against willingness to use in the future among nightclub/festival attendees.
Topics: Adult; Drug-Related Side Effects and Adverse Reactions; Holidays; Humans; Illicit Drugs; Ketamine; M | 2023 |
Esketamine in treatment-resistant depression patients comorbid with substance-use disorder: A viewpoint on its safety and effectiveness in a subsample of patients from the REAL-ESK study.
Topics: Administration, Intranasal; Adult; Antidepressive Agents; Comorbidity; Depression; Depressive Disord | 2023 |
Tusi: a new ketamine concoction complicating the drug landscape.
Topics: Cocaine; Hallucinogens; Humans; Ketamine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; S | 2023 |
Trends in Illicit Ketamine Seizures in the US From 2017 to 2022.
Topics: Humans; Illicit Drugs; Ketamine; Seizures; Substance-Related Disorders | 2023 |
Ketamine uropathy: Clinical experience in a high prevalence center.
Topics: Adult; Female; Humans; Hydronephrosis; Ketamine; Male; Prevalence; Substance-Related Disorders; Urol | 2023 |
Addiction specialists' attitudes toward psychedelics: A National Survey.
Topics: Behavior, Addictive; Hallucinogens; Humans; Ketamine; Substance-Related Disorders; Surveys and Quest | 2023 |
The effects of ketamine and methamphetamine on neurotransmitters, glutamate receptors, and conditioned place preference in rat.
Topics: Animals; Dopamine; Ketamine; Methamphetamine; Monoamine Oxidase; Neurotransmitter Agents; Rats; Rece | 2023 |
Trends and correlates of discordant reporting of drug use among nightclub/festival attendees, 2019-2022.
Topics: Adult; Cocaine; Holidays; Humans; Ketamine; Methamphetamine; Substance-Related Disorders | 2023 |
Drug Use by Music Festival Attendees: A Novel Triangulation Approach Using Self-Reported Data and Test Results of Oral Fluid and Pooled Urine Samples.
Topics: Adult; Amphetamine; Cocaine; Drug Users; Female; Hallucinogens; Holidays; Humans; Illicit Drugs; Ket | 2019 |
Tiletamine detected in a ketamine abuser with altered mental status.
Topics: Adult; Delirium; Humans; Ketamine; Male; Substance-Related Disorders; Tiletamine | 2020 |
Recovery of cognitive functioning following abstinence from ketamine.
Topics: Adult; Anxiety; Cognition; Cognitive Dysfunction; Depression; Excitatory Amino Acid Antagonists; Fem | 2019 |
Simultaneous Quantitative Determination of Amphetamines, Opiates, Ketamine, Cocaine and Metabolites in Human Hair: Application to Forensic Cases of Drug Abuse.
Topics: Adult; Amphetamines; Chromatography, Liquid; Cocaine; Female; Forensic Toxicology; Hair; Humans; Ket | 2020 |
Effectiveness of a brief information, motivation and behavioral skills program on stage transitions and lapse for individuals who use ketamine.
Topics: Adult; Behavior Therapy; Female; Health Knowledge, Attitudes, Practice; Humans; Ketamine; Male; Midd | 2019 |
Ketamine sensitization: Influence of dose, environment, social isolation and treatment interval.
Topics: Anesthetics, Dissociative; Animals; Behavior, Animal; Central Nervous System Sensitization; Disease | 2020 |
Mis-anaesthetized society: expectancies and recreational use of ketamine in Taiwan.
Topics: Adolescent; Adult; Female; Humans; Illicit Drugs; Ketamine; Male; Middle Aged; Motivation; Prevalenc | 2019 |
Commentary on: Zhuo Y, Wang X, Wu J, Zhang S, Deng H, Liu W, et al. Simultaneous quantitative determination of amphetamines, opiates, ketamine, cocaine and metabolites in human hair: application to forensic cases of drug abuse. J Forensic Sci doi: 10.1111
Topics: Amphetamines; Cocaine; Humans; Ketamine; Opiate Alkaloids; Substance-Related Disorders | 2020 |
Authors' Response.
Topics: Amphetamines; Cocaine; Humans; Ketamine; Opiate Alkaloids; Substance-Related Disorders | 2020 |
Dysuria due to benign prostatic hyperplasia of the median lobe with ketamine-associated uropathy in a young male.
Topics: Adult; Dysuria; Humans; Ketamine; Male; Prostatic Hyperplasia; Substance-Related Disorders; Urologic | 2019 |
Development of an addiction index and delineation 15-year trends of illicit drugs from the Taiwan national drug enhancement database.
Topics: Amphetamine-Related Disorders; Anesthetics, Dissociative; Cannabis; Central Nervous System Stimulant | 2020 |
Searching for Treatments for Cocaine Use Disorder: The Quest Continues.
Topics: Cocaine; Cocaine-Related Disorders; Humans; Ketamine; Mindfulness; Substance-Related Disorders | 2019 |
Association of Craving and Depressive Symptoms in Ketamine-Dependent Patients Undergoing Withdrawal Treatment.
Topics: Adolescent; Adult; Anxiety; Behavior, Addictive; Craving; Depression; Female; Humans; Ketamine; Male | 2020 |
[High-risk drug use: epidemiological pattern through hair testing in the forensic context].
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Amphetamine; Cannabinoids; Cocaine; Cross-Sectiona | 2019 |
Substance abuse effects on urinary tract: methamphetamine and ketamine.
Topics: Adult; Cohort Studies; Female; Hong Kong; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Meth | 2019 |
Mortalities of methamphetamine, opioid, and ketamine abusers in Shanghai and Wuhan, China.
Topics: Adolescent; Adult; Age Distribution; Analgesics, Opioid; Carbon Monoxide Poisoning; China; Female; H | 2020 |
GRIN2B Gene Polymorphism in Chronic Ketamine Users.
Topics: Adult; Case-Control Studies; Chronic Disease; Gene Frequency; Genetic Markers; Genotype; Humans; Ill | 2020 |
Authors' Response.
Topics: Amphetamines; Cocaine; Humans; Ketamine; Opiate Alkaloids; Substance-Related Disorders | 2020 |
Sublingual Ketamine: An Option for Increasing Accessibility of Ketamine Treatments for Depression?
Topics: Anesthetics, Dissociative; Antidepressive Agents; Biological Availability; Depressive Disorder, Trea | 2020 |
Preliminary comparative analysis of kynurenine pathway metabolites in chronic ketamine users, schizophrenic patients, and healthy controls.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Ketamine; Kynuren | 2020 |
The Emergence of Deschloro-N-ethyl-ketamine, a Ketamine Analog, in Drug Seizures and Drug Driving Cases in Hong Kong.
Topics: Adult; Automobile Driving; Driving Under the Influence; Forensic Toxicology; Hong Kong; Humans; Illi | 2020 |
Emergence of new psychoactive substance 2-fluorodeschloroketamine: Toxicology and urinary analysis in a cluster of patients exposed to ketamine and multiple analogues.
Topics: Adolescent; Adult; Chromatography, Liquid; Female; Forensic Toxicology; Humans; Illicit Drugs; Ketam | 2020 |
Ketamine beyond anesthesia: Antidepressant effects and abuse potential.
Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Humans; Ketamine; Substance-Related Disor | 2020 |
Cognitive impairment in chronic ketamine abusers.
Topics: Adult; Anesthetics, Dissociative; Chronic Disease; Cognitive Dysfunction; Executive Function; Female | 2020 |
Shifts in Unintentional Exposure to Drugs Among People Who Use Ecstasy in the Electronic Dance Music Scene, 2016-2019.
Topics: Adult; Dancing; Drug Contamination; Female; Hair Analysis; Harm Reduction; Humans; Illicit Drugs; In | 2021 |
Effects of early ketamine exposure on cerebral gray matter volume and functional connectivity.
Topics: Adolescent; Adult; Case-Control Studies; Female; Gray Matter; Humans; Ketamine; Magnetic Resonance I | 2020 |
Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Caudate Nucleus; DNA-Binding Proteins; En | 2020 |
Sleep quality among individuals with ketamine use and the mediating role of craving.
Topics: Adult; Case-Control Studies; Craving; Female; Humans; Ketamine; Logistic Models; Male; Sleep; Substa | 2020 |
Cognitive impairment in ketamine abusers.
Topics: Anesthetics, Dissociative; Cognitive Dysfunction; Humans; Ketamine; Substance-Related Disorders | 2021 |
Ketamine abusers with SLC6A3 rs393795 genotype showed a preliminary association with psychosis and schizophrenia: A pilot case-control study.
Topics: Case-Control Studies; Dopamine Plasma Membrane Transport Proteins; Genotype; Humans; Ketamine; Psych | 2021 |
Ketamine Use Among People Who Regularly Use Ecstasy and Other Illicit Stimulants in Australia: Trends and Characteristics of Use, 2009-2019.
Topics: Adult; Australia; Central Nervous System Stimulants; Cross-Sectional Studies; Female; Harm Reduction | 2021 |
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses.
Topics: Adult; Apolipoprotein A-I; Female; Humans; Ketamine; Male; Proteomics; Substance-Related Disorders; | 2021 |
Fatal intoxication related to two new arylcyclohexylamine derivatives (2F-DCK and 3-MeO-PCE).
Topics: Adult; Cyclohexylamines; Hair; Humans; Illicit Drugs; Ketamine; Male; Psychotropic Drugs; Substance | 2021 |
Increasing Prevalence of Ketamine in Drivers in New York City Including the Identification of 2-Fluoro-Deschloroketamine.
Topics: Adult; Female; Humans; Ketamine; Male; New York City; Prevalence; Retrospective Studies; Substance-R | 2021 |
New psychoactive substance cocktail in an intensive care intoxication case elucidated by molecular networking.
Topics: Adult; Chromatography, Liquid; Critical Care; Humans; Ketamine; Male; Mass Spectrometry; Psychotropi | 2022 |
Recreational ketamine-related deaths notified to the National Programme on Substance Abuse Deaths, England, 1997-2019.
Topics: Adolescent; Adult; Anesthetics, Dissociative; England; Female; Humans; Illicit Drugs; Ketamine; Male | 2021 |
Appetitive Motivation and Regulatory Processes in Adolescent Ketamine Users.
Topics: Adolescent; Executive Function; Humans; Illicit Drugs; Ketamine; Motivation; Substance-Related Disor | 2021 |
Increased Nectin-4 levels in chronic ketamine abusers and the relationship with lower urinary tract symptoms.
Topics: Adult; Cell Adhesion Molecules; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Lower U | 2021 |
Out of the night-time and into the day: Ketamine and MDMA as therapies for mental disorders.
Topics: Hallucinogens; Humans; Ketamine; Mental Disorders; Methamphetamine; N-Methyl-3,4-methylenedioxyamphe | 2021 |
Ketamine-induced bladder fibrosis involves epithelial-to-mesenchymal transition mediated by transforming growth factor-β1.
Topics: Analgesics; Animals; Cell Line; Cystitis; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Fi | 2017 |
Clinical Outcome of Augmentation Enterocystoplasty for Patients with Ketamine-induced Cystitis.
Topics: Adult; Cystitis; Female; Humans; Ketamine; Male; Retrospective Studies; Substance-Related Disorders; | 2017 |
Selective Pharmacological Augmentation of Hippocampal Activity Produces a Sustained Antidepressant-Like Response without Abuse-Related or Psychotomimetic Effects.
Topics: Animals; Antidepressive Agents; Depressive Disorder; Hippocampus; Imidazoles; Ketamine; Lidocaine; P | 2017 |
Oral ketamine induced pathological changes of the urinary tract in a rat model.
Topics: Animals; Inflammation; Ketamine; Kidney; Male; Models, Animal; Rats, Sprague-Dawley; Substance-Relat | 2017 |
Illicit drug consumption in school populations measured by wastewater analysis.
Topics: Amphetamine; Cannabinoids; Cannabis; Cocaine; Humans; Illicit Drugs; Italy; Ketamine; Mass Spectrome | 2017 |
Risk Factors of Lower Urinary Tract Syndrome among Ketamine Users.
Topics: Adult; Analgesics; Comorbidity; Cross-Sectional Studies; Cystitis, Interstitial; Depression; Female; | 2018 |
Clinical pattern and prevalence of upper gastrointestinal toxicity in patients abusing ketamine.
Topics: Abdominal Pain; Administration, Inhalation; Adolescent; Adult; Analgesics; Anemia; Case-Control Stud | 2017 |
Recreational drug use at a major music festival: trend analysis of anonymised pooled urine.
Topics: Adolescent; Adult; Amphetamine; Chromatography, High Pressure Liquid; Cocaine; Cross-Sectional Studi | 2018 |
Depression in chronic ketamine users: Sex differences and neural bases.
Topics: Anesthetics, Dissociative; Depression; Female; Gyrus Cinguli; Humans; Ketamine; Magnetic Resonance I | 2017 |
Substance abuse in the anesthesia block room by a patient.
Topics: Anesthesia, Intravenous; Elective Surgical Procedures; Humans; Hypnotics and Sedatives; Ketamine; Mi | 2017 |
2-oxo-PCE: ketamine analogue on the streets.
Topics: Drug Evaluation, Preclinical; Forensic Toxicology; Hong Kong; Humans; Illicit Drugs; Ketamine; Subst | 2017 |
Effects of rhynchophylline on the hippocampal miRNA expression profile in ketamine-addicted rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Computational Biology; Cy | 2018 |
The potential for occupational exposure of veterinarians to ketamine resulting in positive drug tests.
Topics: False Positive Reactions; Hair; Humans; Ketamine; Male; Occupational Exposure; Substance Abuse Detec | 2018 |
Intoxication by the synthetic cannabinoid 5-fluoro-ABD, acquired as ketamine.
Topics: Adult; Cannabinoids; Dystonia; Excitatory Amino Acid Antagonists; Humans; Ketamine; Male; Marijuana | 2018 |
Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia.
Topics: Adult; Cognition; Cognitive Dysfunction; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine | 2018 |
Other drug use does not impact cognitive impairments in chronic ketamine users.
Topics: Adolescent; Adult; Cognition; Cognitive Dysfunction; Executive Function; Female; Humans; Illicit Dru | 2018 |
Patterns of injecting and non-injecting drug use by sexual behaviour in people who inject drugs attending services in England, Wales and Northern Ireland, 2013-2016.
Topics: Adult; Cocaine; England; Female; Heterosexuality; Humans; Illicit Drugs; Ketamine; Male; Methadone; | 2018 |
Vascular fibrinoid necrosis in the urinary bladder of ketamine abusers: A new finding that may provide a clue to the pathogenesis of ketamine-induced vesicopathy.
Topics: Adult; Cystitis; Female; Humans; Ketamine; Necrosis; Substance-Related Disorders; Urinary Bladder; U | 2019 |
Low serum level of epidermal growth factor in chronic ketamine users.
Topics: Adolescent; Adult; Epidermal Growth Factor; Excitatory Amino Acid Antagonists; Female; Humans; Ketam | 2018 |
Can a Framework Be Established for the Safe Use of Ketamine?
Topics: Depression; Depressive Disorder; Double-Blind Method; Humans; Ketamine; Substance-Related Disorders; | 2018 |
Cognitive profile of ketamine-dependent patients compared with methamphetamine-dependent patients and healthy controls.
Topics: Adult; Amphetamine-Related Disorders; Attention; Case-Control Studies; Cognition; Cross-Sectional St | 2018 |
The profile of cognitive impairments in chronic ketamine users.
Topics: Adult; Cognition; Cognitive Dysfunction; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine | 2018 |
Complete reversal of the clinical symptoms and image morphology of ketamine cystitis after intravesical hyaluronic acid instillation: A case report.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Adult; Analgesics; Cystitis; Cystoscopy; Diagn | 2018 |
Cluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE.
Topics: Adult; Chromatography, Liquid; Confusion; Consciousness Disorders; Female; Forensic Toxicology; Gas | 2018 |
Detecting the diverted use of psychoactive drugs by adolescents and young adults: A pilot study.
Topics: Adolescent; Adult; Age Factors; Antitussive Agents; Codeine; Female; France; Humans; Ketamine; Male; | 2018 |
Sexual and bladder dysfunction in male ketamine abusers: A large-scale questionnaire study.
Topics: Adult; Erectile Dysfunction; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Risk Factors; Sub | 2018 |
Difference in long-term relapse rates between youths with ketamine use and those with stimulants use.
Topics: Adolescent; Central Nervous System Stimulants; Child; Excitatory Amino Acid Antagonists; Female; Hum | 2018 |
Chasing the rainbow: pleasure, sex-based sociality and consumerism in navigating and exiting the Irish Chemsex scene.
Topics: Adult; Harm Reduction; Homosexuality, Male; Humans; Illicit Drugs; Ireland; Ketamine; Male; Methamph | 2019 |
Ketamine analogues multiplying in Hong Kong.
Topics: Anesthetics, Dissociative; Hong Kong; Humans; Ketamine; Substance-Related Disorders | 2019 |
A survey for ketamine abuse and its relation to the lower urinary tract symptoms in Taiwan.
Topics: Administration, Intravesical; Adult; Cystitis, Interstitial; Female; Humans; Ketamine; Lower Urinary | 2019 |
A validated GC-MS method for ketamine and norketamine in hair and its use in authentic cases.
Topics: Adult; Anesthetics, Dissociative; Gas Chromatography-Mass Spectrometry; Hair; Humans; Ketamine; Limi | 2019 |
Epidemiologic characteristics and risk factors in patients with ketamine-associated lower urinary tract symptoms accompanied by urinary tract infection: A cross-sectional study.
Topics: Adult; Cross-Sectional Studies; Female; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Risk F | 2019 |
An unusual cause of cholangiopathy.
Topics: Anesthetics, Dissociative; Bile Duct Diseases; Cholangiopancreatography, Magnetic Resonance; Endoson | 2019 |
Promises and concerns regarding the use of ketamine and esketamine in the treatment of depression.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Antidepressive Agents; Brain-Derived Neurotro | 2019 |
Behavioral Changes and Neuronal Damage in Rhesus Monkeys after 10 Weeks of Ketamine Administration Involve Prefrontal Cortex Dopamine D2 Receptor and Dopamine Transporter.
Topics: Animals; Body Weight; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-R | 2019 |
Chronic ketamine abuse is associated with orexin-A reduction and ACTH elevation.
Topics: Adrenocorticotropic Hormone; Adult; Anxiety; Case-Control Studies; Craving; Depressive Disorder; Fem | 2020 |
Effects of chronic ketamine use on frontal and medial temporal cognition.
Topics: Attention; Case-Control Studies; Cognition Disorders; Dose-Response Relationship, Drug; Excitatory A | 2013 |
Ketamine is associated with lower urinary tract signs and symptoms.
Topics: Adult; Anesthetics, Dissociative; Data Collection; Data Interpretation, Statistical; Dysuria; Female | 2013 |
Relationship between cognitive impairment and depressive symptoms in current ketamine users.
Topics: Adolescent; Adult; Analysis of Variance; Case-Control Studies; Cognition Disorders; Cross-Sectional | 2013 |
Acute ketamine-induced neuroplasticity: ribosomal protein S6 phosphorylation expression in drug addiction-related rat brain areas.
Topics: Amygdala; Anesthetics, Dissociative; Animals; Astrocytes; Brain; CA1 Region, Hippocampal; CA3 Region | 2013 |
Concentrations of drugs determined in blood samples collected from suspected drugged drivers in England and Wales.
Topics: Adolescent; Adult; Amphetamine; Automobile Driving; Central Nervous System Depressants; Chromatograp | 2013 |
Renal infarction secondary to ketamine abuse.
Topics: Analgesics; Female; Humans; Infarction; Ketamine; Kidney; Substance-Related Disorders; Young Adult | 2013 |
Ketamine abuse, biliary tract disease, and secondary sclerosing cholangitis.
Topics: Administration, Inhalation; Anesthetics, Dissociative; Biliary Tract Diseases; Biopsy; Cholangitis, | 2013 |
'Ketamine-induced ulcerative cystitis' is perhaps better labelled 'ketamine-induced uropathy'.
Topics: Anesthetics, Dissociative; Animals; Cystitis; Humans; Ketamine; Male; Memory Disorders; Substance-Re | 2013 |
Ketamine and damage to the urinary tract.
Topics: Anesthetics, Dissociative; Animals; Cystitis; Humans; Ketamine; Male; Memory Disorders; Substance-Re | 2013 |
'Addiction' in adolescence: who is really losing control?
Topics: Anesthetics, Dissociative; Animals; Cystitis; Humans; Ketamine; Male; Memory Disorders; Substance-Re | 2013 |
Traditional Chinese medicine diagnoses in persons with ketamine abuse.
Topics: Adolescent; Adult; Aged; Diagnosis, Differential; Female; Heart; Humans; Ketamine; Kidney; Liver; Ma | 2013 |
Clinical outcomes of augmentation cystoplasty in patients suffering from ketamine-related bladder contractures.
Topics: Adult; Contracture; Creatinine; Female; Humans; Ketamine; Male; Renal Insufficiency; Substance-Relat | 2013 |
Cognitive impairments in poly-drug ketamine users.
Topics: Anxiety; Case-Control Studies; Cognition Disorders; Depression; Excitatory Amino Acid Antagonists; E | 2013 |
Abnormalities in white matter microstructure associated with chronic ketamine use.
Topics: Adult; Brain Chemistry; Chronic Disease; Diffusion Tensor Imaging; Female; Humans; Ketamine; Male; M | 2014 |
Drug testing physicians for substances of abuse: case report of a false-positive result.
Topics: Anesthesiology; Anesthetics, Dissociative; False Positive Reactions; Humans; Ketamine; Physician Imp | 2013 |
Are sexes affected differently by ketamine? An exploratory study in ketamine users.
Topics: Case-Control Studies; Cognition; Female; Humans; Ketamine; Linear Models; Male; Memory; Sex Factors; | 2014 |
Nerve hyperplasia: a unique feature of ketamine cystitis.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Cystitis; Humans; Hyperplasia; Illicit Dr | 2013 |
Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users.
Topics: Adult; Aspartic Acid; Brain; Female; Glutamic Acid; Glutamine; Humans; Ketamine; Magnetic Resonance | 2014 |
Dimethyltryptamine (DMT): prevalence, user characteristics and abuse liability in a large global sample.
Topics: Adult; Australia; Behavior, Addictive; Drug Users; Europe; Hallucinogens; Humans; Ketamine; Lysergic | 2014 |
[Effect of electroacupuncture intervention at different time-points in a day on expression of c-fos and neuronal nitric oxide synthase in medial prefrontal cortex in ketamine addiction rats].
Topics: Acupuncture Points; Animals; Electroacupuncture; Humans; Ketamine; Male; Nitric Oxide Synthase Type | 2013 |
Estimating daily and diurnal variations of illicit drug use in Hong Kong: a pilot study of using wastewater analysis in an Asian metropolitan city.
Topics: Chromatography, Liquid; Cocaine; Hong Kong; Humans; Ketamine; Methamphetamine; N-Methyl-3,4-methylen | 2013 |
Ketamine should be upgraded from class C to class B drug, committee says.
Topics: Analgesics; Drug and Narcotic Control; Humans; Illicit Drugs; Ketamine; Substance-Related Disorders; | 2013 |
Evaluation of the extent of ketamine-induced uropathy: the role of CT urography.
Topics: Adult; Analgesics; Female; Humans; Hydronephrosis; Ketamine; Male; Organ Size; Retrospective Studies | 2014 |
[Urinary tract lesions associated to ketamine consumption].
Topics: Cystitis; Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; Male; Substance-Relate | 2014 |
Ketamine-induced cholangiopathy.
Topics: Adult; Biliary Tract Diseases; Cholangiopancreatography, Endoscopic Retrograde; Female; Humans; Keta | 2014 |
Club drugs: coming to a patient near you.
Topics: Adolescent; Adult; Female; Flunitrazepam; Humans; Illicit Drugs; Ketamine; Lysergic Acid Diethylamid | 2014 |
Dissociable effects of the noncompetitive NMDA receptor antagonists ketamine and MK-801 on intracranial self-stimulation in rats.
Topics: Anesthetics, Dissociative; Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; | 2014 |
Liver injury is common among chronic abusers of ketamine.
Topics: Adult; Bile Ducts; Biopsy; Chemical and Drug Induced Liver Injury; Cholangiopancreatography, Magneti | 2014 |
WHO expert committee on drug dependence.
Topics: Congresses as Topic; Drug and Narcotic Control; Drug Evaluation; Guidelines as Topic; Humans; Hydrox | 2012 |
One-stop clinic for ketamine-associated uropathy: report on service delivery model, patients' characteristics and non-invasive investigations at baseline by a cross-sectional study in a prospective cohort of 318 teenagers and young adults.
Topics: Adolescent; Adult; Analysis of Variance; Cross-Sectional Studies; Female; Hong Kong; Humans; Illicit | 2014 |
Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Cocaine; Diseas | 2014 |
Chronic hematuria and abdominal pain.
Topics: Abdominal Pain; Adolescent; Chronic Disease; Common Bile Duct; Cystitis; Dilatation, Pathologic; Fem | 2014 |
[Ketamine-induced urinary symptoms].
Topics: Adult; Analgesics; Hallucinogens; Hematuria; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Sy | 2014 |
Reply to: Rapid antidepressant effects and abuse liability of ketamine.
Topics: Animals; Antidepressive Agents; Humans; Ketamine; Substance-Related Disorders | 2014 |
Rapid antidepressant effects and abuse liability of ketamine.
Topics: Animals; Antidepressive Agents; Depression; Humans; Ketamine; Receptors, N-Methyl-D-Aspartate; Subst | 2014 |
Drug use and sexual risk among gay and bisexual men who frequent party venues.
Topics: Adult; Amphetamine-Related Disorders; Bisexuality; Homosexuality, Male; Humans; Ketamine; Male; Meth | 2014 |
Ketamine cystitis: practical considerations in management.
Topics: Adolescent; Adult; Cystitis; Female; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Middle Ag | 2014 |
Ketamine use in Taiwan: Moral panic, civilizing processes, and democratization.
Topics: Adolescent; Drug and Narcotic Control; Female; Humans; Illicit Drugs; Ketamine; Male; Morals; Panic; | 2014 |
Ketamine alters cortical integration of GABAergic interneurons and induces long-term sex-dependent impairments in transgenic Gad67-GFP mice.
Topics: Animals; Apoptosis; Calcium; Cell Differentiation; Cerebral Cortex; Female; gamma-Aminobutyric Acid; | 2014 |
Ketamine abuse-induced obstructive nephropathy and kidney injury.
Topics: Adult; Female; Humans; Ketamine; Kidney; Kidney Diseases; Substance-Related Disorders | 2014 |
Psychiatric morbidity in ketamine users attending counselling and youth outreach services.
Topics: Adolescent; Adult; Anxiety Disorders; Comorbidity; Counseling; Depressive Disorder; Excitatory Amino | 2015 |
Serum brain-derived neurotrophic factor and nerve growth factor decreased in chronic ketamine abusers.
Topics: Adult; Brain-Derived Neurotrophic Factor; Female; Humans; Ketamine; Male; Nerve Growth Factor; Subst | 2014 |
Long-term ketamine abuse induces cystitis in rats by impairing the bladder epithelial barrier.
Topics: Animals; Biomarkers; Blotting, Western; Cystitis; Dose-Response Relationship, Drug; Epithelium; Hist | 2014 |
Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Cocaine-Related Disorders; Cross-Sectional Studies | 2015 |
Education and Imaging. Hepatobiliary and pancreatic: cholangiopathy in ketamine user--an emerging new condition.
Topics: Adult; Cholestasis; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Sphincter of Oddi D | 2014 |
Effect of rhynchophylline on conditioned place preference on expression of NR2B in methamphetamine-dependent mice.
Topics: Alkaloids; Animals; Conditioning, Operant; Drug Administration Schedule; Excitatory Amino Acid Antag | 2014 |
Gender differences in subjective discontinuation symptoms associated with ketamine use.
Topics: Adolescent; Adult; Analgesics; Female; Humans; Ketamine; Male; Middle Aged; Sex Factors; Substance W | 2014 |
Lessons learned from Asian Urology.
Topics: China; Hong Kong; Humans; Ketamine; Substance-Related Disorders; United Kingdom; Urologic Diseases; | 2014 |
Where next in ketamine uropathy? Dedicated management centres?
Topics: Female; Humans; Illicit Drugs; Ketamine; Male; Pelvic Pain; Substance-Related Disorders; Urologic Di | 2014 |
Reliability and validity of the Severity of Dependence Scale in a Chinese sample of treatment-seeking ketamine users.
Topics: Adolescent; Adult; Analgesics; Female; Hong Kong; Humans; Ketamine; Male; Middle Aged; Patient Accep | 2014 |
Cut-off proposal for the detection of ketamine in hair.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Chromatography, High Pressure Liquid; Female; Forensic | 2015 |
Methoxetamine, a ketamine derivative, produced conditioned place preference and was self-administered by rats: Evidence of its abuse potential.
Topics: Animals; Conditioning, Psychological; Cyclohexanones; Cyclohexylamines; Dose-Response Relationship, | 2015 |
Intensive ketamine use for multiple years: A case report.
Topics: Adult; Antidepressive Agents; Behavior, Addictive; Bipolar Disorder; Humans; Ketamine; Male; Self Me | 2015 |
Methoxetamine: An early report on the motivations for use, effect profile and prevalence of use in a UK clubbing sample.
Topics: Adult; Cross-Sectional Studies; Cyclohexanones; Cyclohexylamines; Female; Hallucinogens; Humans; Ill | 2016 |
Re: One-stop clinic for ketamine-associated uropathy: report on service delivery model, patients' characteristics and non-invasive investigations at baseline by a cross-sectional study in a prospective cohort of 318 teenagers and young adults.
Topics: Female; Humans; Illicit Drugs; Ketamine; Male; Pelvic Pain; Substance-Related Disorders; Urologic Di | 2015 |
Serum level of vascular endothelial growth factor decreased in chronic ketamine abusers.
Topics: Adult; Case-Control Studies; Female; Humans; Ketamine; Male; Substance-Related Disorders; Vascular E | 2015 |
Ketamine Abuse Syndrome: Hepatobiliary and Urinary Pathology Among Adolescents in Flushing, NY.
Topics: Abdominal Pain; Adolescent; Adult; Anesthetics, Dissociative; Asian; Delayed Diagnosis; Emigrants an | 2017 |
Macro Social Flaws and Intervention's Unfinished Business: A Personal Note on Young People's Drug Use in Hong Kong.
Topics: Hong Kong; Humans; Ketamine; Risk-Taking; Social Environment; Social Norms; Socioeconomic Factors; S | 2015 |
Relationship of serum levels of TNF-α, IL-6 and IL-18 and schizophrenia-like symptoms in chronic ketamine abusers.
Topics: Adolescent; Adult; Blood Chemical Analysis; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid | 2015 |
Re: Long-Term Ketamine Abuse Induces Cystitis in Rats by Impairing the Bladder Epithelial Barrier.
Topics: Animals; Cystitis; Epithelium; Ketamine; Substance-Related Disorders; Urinary Bladder | 2016 |
The clinical presentation and diagnosis of ketamine-associated urinary tract dysfunction in Singapore.
Topics: Adult; Cystitis; Cystoscopy; Female; Fluoroscopy; Humans; Ketamine; Lower Urinary Tract Symptoms; Ma | 2015 |
Profiling the psychotic, depressive and anxiety symptoms in chronic ketamine users.
Topics: Adolescent; Adult; Anxiety; China; Comorbidity; Depression; Excitatory Amino Acid Antagonists; Femal | 2016 |
Re: Ketamine Cystitis: Practical Considerations in Management.
Topics: Cystitis; Female; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Substance-Related Disorders | 2016 |
Potential Risks of Poorly Monitored Ketamine Use in Depression Treatment.
Topics: Alcohol-Related Disorders; Analgesics; Antidepressive Agents; Depressive Disorder, Major; Depressive | 2016 |
Occurrence of illicit drugs in surface waters in China.
Topics: Child; China; Environmental Monitoring; Humans; Illicit Drugs; Ketamine; Lakes; Methamphetamine; Riv | 2016 |
Patient characteristics for different therapeutic strategies in the management ketamine cystitis.
Topics: Adolescent; Adult; Conservative Treatment; Cystitis; Female; Humans; Ketamine; Male; Retrospective S | 2017 |
Reliability, convergent and structural validity and cut-off score of the Severity of Dependence Scale for recreational ketamine users.
Topics: Adult; Analgesics; Cross-Sectional Studies; Drug Users; Female; Humans; Illicit Drugs; Ketamine; Mal | 2016 |
The similarities and differences in impulsivity and cognitive ability among ketamine, methadone, and non-drug users.
Topics: Adolescent; Adult; Cognition; Decision Making; Drug Users; Female; Gambling; Humans; Impulsive Behav | 2016 |
Ketamine-snorting-induced nasal septum perforation.
Topics: Administration, Intranasal; Analgesics; Epistaxis; Humans; Ketamine; Male; Nasal Septal Perforation; | 2016 |
Population-based survey of the prevalence of lower urinary tract symptoms in adolescents with and without psychotropic substance abuse.
Topics: Adolescent; Age Factors; Child; Cross-Sectional Studies; Female; Hong Kong; Humans; Ketamine; Lower | 2016 |
Major Depressive Disorder Induced by Chronic Ketamine Abuse: A Case Report.
Topics: Adult; Anesthetics, Dissociative; Depressive Disorder, Major; Humans; Ketamine; Male; Substance-Rela | 2016 |
Alcohol Use Disorder as a Possible Predictor of Electroconvulsive Therapy Response.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alcoholism; Anesthesia; Anesthetics, Dissociative; Benz | 2017 |
Changes in hippocampal AMPA receptors and cognitive impairments in chronic ketamine addiction models: another understanding of ketamine CNS toxicity.
Topics: Animals; Central Nervous System; Cognition Disorders; Dose-Response Relationship, Drug; Hippocampus; | 2016 |
Decreased Thalamocortical Connectivity in Chronic Ketamine Users.
Topics: Adult; Anesthetics, Dissociative; Brain Mapping; Cerebral Cortex; Female; Functional Neuroimaging; H | 2016 |
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Se | 2017 |
Rates and Correlates of Syphilis Reinfection in Men Who Have Sex with Men.
Topics: Adult; Anesthetics, Dissociative; Coinfection; Follow-Up Studies; HIV Infections; Homosexuality, Mal | 2017 |
Alcohol Triggers Reemergence of Ketamine-Like Experience in a Ketamine Ex-User.
Topics: Adult; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Humans; Ketam | 2017 |
Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.
Topics: Animals; Cognition; Cyclohexanes; Excitatory Amino Acid Antagonists; Ketamine; Male; Motor Activity; | 2017 |
Cannabinoid CB(1) receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats.
Topics: Animals; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relati | 2008 |
Multivariate modeling of club drug use initiation among gay and bisexual men.
Topics: Adolescent; Adult; Aged; Bisexuality; Cocaine; Homosexuality, Male; Humans; Ketamine; Longitudinal S | 2008 |
Ketamine pretreatment exacerbated 3,4-methylenedioxymethamphetamine-induced central dopamine toxicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transpo | 2008 |
The destruction of the lower urinary tract by ketamine abuse: a new syndrome?
Topics: Adolescent; Adult; Cystoscopy; Female; Humans; Ketamine; Male; Retrospective Studies; Substance-Rela | 2008 |
Consider ketamine misuse in patients with urinary symptoms.
Topics: Anesthetics, Dissociative; Humans; Illicit Drugs; Ketamine; Substance-Related Disorders; Urination D | 2008 |
The destruction of the lower urinary tract by ketamine abuse: a new syndrome?
Topics: Humans; Ketamine; Substance-Related Disorders; Syndrome; Urinary Tract | 2008 |
Use of and attitudes toward club drugs by medical students.
Topics: Adult; Anesthetics, Intravenous; Anti-Anxiety Agents; Central Nervous System Stimulants; Dextrometho | 2008 |
Dinosaur girls, candy girls, and Trinity: voices of Taiwanese club drug users.
Topics: Adolescent; Adult; Data Collection; Female; Focus Groups; Hallucinogens; Health Personnel; Humans; I | 2008 |
Frequent visits with urinary symptoms: subtle signs of ketamine abuse.
Topics: Adolescent; Adult; Analgesics; Cystitis, Interstitial; Female; Humans; Ketamine; Substance-Related D | 2008 |
Is persistent ketamine use a valid model of the cognitive and oculomotor deficits in schizophrenia?
Topics: Adolescent; Adult; Cognition Disorders; Excitatory Amino Acid Antagonists; Female; Humans; Intellige | 2009 |
Ketamine use, cognition and psychological wellbeing: a comparison of frequent, infrequent and ex-users with polydrug and non-using controls.
Topics: Adolescent; Adult; Analgesics; Child; Cognition Disorders; Dissociative Disorders; Dose-Response Rel | 2009 |
Ketamine associated cystitis - a case report.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cystitis; Cystoscopy; Emergency Treatment; Humans; Keta | 2009 |
Dilated common bile ducts mimicking choledochal cysts in ketamine abusers.
Topics: Adult; Analgesics; Choledochal Cyst; Common Bile Duct Diseases; Diagnosis, Differential; Dilatation, | 2009 |
Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically.
Topics: Animals; Benzodiazepines; Binding Sites; Dose-Response Relationship, Drug; Drug Tolerance; Flunitraz | 2009 |
Dilated common bile ducts in ketamine abusers.
Topics: Adult; Common Bile Duct; Female; Humans; Ketamine; Substance-Related Disorders | 2009 |
Sildenafil (Viagra) and club drug use in gay and bisexual men: the role of drug combinations and context.
Topics: Bisexuality; Cocaine; Drug Combinations; Homosexuality, Male; Humans; Illicit Drugs; Ketamine; Leisu | 2007 |
Cystitis associated with chronic ketamine abuse.
Topics: Chronic Disease; Cystitis; Female; Humans; Ketamine; Male; Substance-Related Disorders | 2009 |
Ketamine-associated bladder dysfunction.
Topics: Adult; Female; Humans; Ketamine; Male; Substance-Related Disorders; Urinary Bladder Diseases; Young | 2009 |
Mice are prone to kidney pathology after prolonged ketamine addiction.
Topics: Anesthetics, Dissociative; Animals; Choline O-Acetyltransferase; Disease Progression; Ketamine; Kidn | 2009 |
[The knowledge about "date rape drugs" among Polish students].
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Crime Victims; Female; Flunitrazepam; Health Knowl | 2009 |
Methylenedioxymethamphetamine-related deaths in Taiwan: 2001-2008.
Topics: Accidents; Adolescent; Adult; Autopsy; Cause of Death; Excitatory Amino Acid Antagonists; Female; Fl | 2009 |
Consequences of chronic ketamine self-administration upon neurocognitive function and psychological wellbeing: a 1-year longitudinal study.
Topics: Adult; Cognition Disorders; Delusions; Depressive Disorder; Dissociative Disorders; Dose-Response Re | 2010 |
Typology of club drug use among young adults recruited using time-space sampling.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Cocaine; Dopamine Uptake Inhibitors; Drug Users; Excitator | 2010 |
Commentary on Morgan et al. (2010): ketamine abuse: first medical evidence of harms we should confront.
Topics: Delusions; Depressive Disorder; Excitatory Amino Acid Antagonists; Humans; Illicit Drugs; Ketamine; | 2010 |
Near-death states reported in a sample of 50 misusers.
Topics: Adult; Aged; Analgesics; Death; Female; Humans; Interviews as Topic; Ketamine; London; Male; Middle | 2010 |
Upper gastrointestinal problems in inhalational ketamine abusers.
Topics: Administration, Inhalation; Adult; Analgesics; China; Cohort Studies; Female; Gastritis; Humans; Inc | 2010 |
A fast screening procedure for ketamine and metabolites in urine samples with tandem mass spectrometry.
Topics: Calibration; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Gas Chromatography-Mass Sp | 2010 |
Breaking the drug addiction cycle is not easy in ketamine abusers.
Topics: Analgesics; Humans; Illicit Drugs; Ketamine; Substance-Related Disorders; Urinary Bladder Diseases | 2010 |
Frontal white matter abnormalities following chronic ketamine use: a diffusion tensor imaging study.
Topics: Adult; Diffusion Tensor Imaging; Female; Frontal Lobe; Humans; Ketamine; Male; Nerve Fibers, Myelina | 2010 |
Suicide by hanging under the influence of ketamine and ethanol.
Topics: Adult; Anesthetics, Dissociative; Asphyxia; Carotid Artery Injuries; Carotid Artery, Common; Central | 2010 |
Simultaneous quantification of amphetamines, caffeine and ketamine in urine by hollow fiber liquid phase microextraction combined with gas chromatography-flame ionization detector.
Topics: Amphetamines; Caffeine; Calibration; Chromatography, Gas; Drug Monitoring; Flame Ionization; Humans; | 2010 |
Ketamine-associated lower urinary tract destruction: a new radiological challenge.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Cystoscopy; Delayed Diagnosis; Female; Humans; Ketamin | 2010 |
Infant with in utero ketamine exposure: quantitative measurement of residual dosage in hair.
Topics: Adult; Female; Fetus; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Ketamine; | 2010 |
Reduced dorsal prefrontal gray matter after chronic ketamine use.
Topics: Adult; Anesthetics, Dissociative; Atrophy; Brain Mapping; Female; Humans; Ketamine; Magnetic Resonan | 2011 |
Quantifying the psychological effects of ketamine: from euphoria to the k-Hole.
Topics: Analgesics; England; Female; Health Surveys; Humans; Illicit Drugs; Ketamine; Male; Schizotypal Pers | 2010 |
Permanent deficits in brain functions caused by long-term ketamine treatment in mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Blotting, Western; Body Weight; Ca | 2011 |
Ketamine self-administration in the rat: evidence for a critical role of setting.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Psychological; C | 2011 |
Chronic ketamine use increases serum levels of brain-derived neurotrophic factor.
Topics: Adult; Brain-Derived Neurotrophic Factor; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; E | 2011 |
Ketamine as a primary predictor of out-of-body experiences associated with multiple substance use.
Topics: Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Delusions; Female; Humans; Ketamine; M | 2011 |
Ureteric intestinal metaplasia in association with chronic recreational ketamine abuse.
Topics: Adult; Anesthetics, Dissociative; Cystitis; Humans; Intestines; Ketamine; Male; Metaplasia; Spina Bi | 2011 |
[Anesthesia in drug addiction].
Topics: Anesthesia; Cannabinoids; Cocaine-Related Disorders; Hallucinogens; Humans; Ketamine; Opioid-Related | 2011 |
Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.
Topics: Adult; Anesthetics, Dissociative; Biliary Tract; Cholangiopancreatography, Endoscopic Retrograde; Ch | 2011 |
[Effects of electroacupuncture on expression of tyrosine hydroxylase and c-fos in hippocampal CA 1 area in ketamine-addiction rats].
Topics: Animals; Disease Models, Animal; Electroacupuncture; Female; Hippocampus; Humans; Ketamine; Male; Pr | 2011 |
Individual differences in rhesus monkeys' demand for drugs of abuse.
Topics: Anesthetics; Animals; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Ethanol; F | 2012 |
Downregulation in the human and mice cerebella after ketamine versus ketamine plus ethanol treatment.
Topics: Analgesics; Animals; Apoptosis; Central Nervous System Depressants; Cerebellum; Drug Interactions; E | 2012 |
Persistence of urinary symptoms after cessation of ketamine abuse.
Topics: Excitatory Amino Acid Antagonists; Female; Female Urogenital Diseases; Humans; Ketamine; Quality of | 2011 |
Urinary symptoms and impaired quality of life in female ketamine users: persistence after cessation of use.
Topics: Body Mass Index; Excitatory Amino Acid Antagonists; Female; Female Urogenital Diseases; Humans; Keta | 2011 |
Interstitial cystitis symptoms associated with ketamine abuse: the first Japanese case.
Topics: Cystitis, Interstitial; Humans; Japan; Ketamine; Male; Middle Aged; Substance-Related Disorders | 2011 |
[Ketamine is used again by both physicians and addicts].
Topics: Analgesics; Anesthetics, Dissociative; Hallucinogens; Humans; Ketamine; Substance-Related Disorders | 2011 |
Ketamine-associated vesicopathy.
Topics: Adolescent; Analgesics; Biopsy; Cystitis; Cystoscopy; Diagnosis, Differential; Disease Management; H | 2012 |
'Walking-stick ureters' in ketamine abuse.
Topics: Adult; Female; Humans; Ketamine; Substance-Related Disorders; Ureteral Obstruction | 2011 |
Magnetic solid-phase extraction using magnetic hypercrosslinked polymer for rapid determination of illegal drugs in urine.
Topics: Amphetamines; Cross-Linking Reagents; Humans; Ketamine; Magnetic Phenomena; Magnetics; Polymers; Ref | 2011 |
AMPA receptor potentially participates in the mediation of the increased brain-derived neurotrophic factor following chronic ketamine use.
Topics: Brain-Derived Neurotrophic Factor; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male | 2012 |
Moxifloxacin relieves the persistent symptoms of lower urinary tract after cessation of ketamine abuse.
Topics: Excitatory Amino Acid Antagonists; Female; Female Urogenital Diseases; Humans; Ketamine; Quality of | 2011 |
Sexual dysfunction in women with ketamine cystitis: a case-control study.
Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Cystitis, Interstitial; Excitatory Amino Acid | 2012 |
[Ketamine-induced vesicopathy].
Topics: Administration, Intranasal; Administration, Intravesical; Adult; Analgesics; Botulinum Toxins, Type | 2012 |
[Ketamine-associated urological symptoms].
Topics: Cystoscopy; Female; Humans; Ketamine; Substance-Related Disorders; Urinary Tract; Urologic Diseases; | 2012 |
Anomalous bodily-self experiences among recreational ketamine users.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Body Image; Depersonalization; Female; Humans; Illicit | 2012 |
Recreational drug use: an emerging concern among venue-based male sex workers in China.
Topics: Acquired Immunodeficiency Syndrome; China; Condoms; Herpes Genitalis; Herpesvirus 2, Human; Homosexu | 2012 |
The Chinese version of the pelvic pain and urgency/frequency symptom scale: a useful assessment tool for street-ketamine abusers with lower urinary tract symptoms.
Topics: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Ketamine; Language; Lower Urinary Tract | 2012 |
Neurocognitive function and schizophrenia-proneness in individuals dependent on ketamine, on high potency cannabis ('skunk') or on cocaine.
Topics: Adolescent; Adult; Attention; Case-Control Studies; Cocaine-Related Disorders; Cognition Disorders; | 2012 |
Acute and chronic toxicity pattern in ketamine abusers in Hong Kong.
Topics: Adolescent; Adult; Child; Cohort Studies; Female; Hong Kong; Humans; Ketamine; Male; Substance Abuse | 2012 |
Alterations in regional homogeneity of resting-state brain activity in ketamine addicts.
Topics: Adult; Anesthetics, Intravenous; Brain; Brain Mapping; Case-Control Studies; Female; Humans; Ketamin | 2012 |
Ketamine-associated urinary tract dysfunction: an underrecognized clinical entity.
Topics: Administration, Intravesical; Adult; Biopsy; China; Cystoscopy; Female; Humans; Hyaluronic Acid; Ill | 2012 |
Gourd-shaped bladder associated with ketamine abuse.
Topics: Adult; Cystitis; Dysuria; Hematuria; Humans; Illicit Drugs; Ketamine; Lower Urinary Tract Symptoms; | 2012 |
Individual and peer factors associated with ketamine use among adolescents in Taiwan.
Topics: Adolescent; Anesthetics, Dissociative; Cross-Sectional Studies; Emotions; Female; Humans; Ketamine; | 2012 |
[Effects of electroacupuncture intervention at different time in A day on expression of tyrosine hydroxylase and C-fos in nucleus accumbens in ketamine addiction rats].
Topics: Animals; Electroacupuncture; Humans; Ketamine; Male; Nucleus Accumbens; Proto-Oncogene Proteins c-fo | 2012 |
Associative blocking to reward-predicting cues is attenuated in ketamine users but can be modulated by images associated with drug use.
Topics: Adult; Association Learning; Cues; Delusions; Depression; Excitatory Amino Acid Antagonists; Female; | 2013 |
[Imaging features of urinary dysfunction associated with ketamine abuse].
Topics: Adolescent; Adult; Female; Humans; Ketamine; Lower Urinary Tract Symptoms; Magnetic Resonance Imagin | 2012 |
Gender differences in abusers of amphetamine-type stimulants and ketamine in southwestern China.
Topics: Adult; Age Factors; Amphetamine-Related Disorders; Anesthetics, Dissociative; Central Nervous System | 2013 |
Ketamine bladder syndrome: an important differential diagnosis when assessing a patient with persistent lower urinary tract symptoms.
Topics: Adult; Diagnosis, Differential; Humans; Ketamine; Lower Urinary Tract Symptoms; Male; Nocturia; Subs | 2012 |
Chronic ketamine exposure induces permanent impairment of brain functions in adolescent cynomolgus monkeys.
Topics: Adolescent; Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; | 2014 |
Pre-exposure to related substances induced place preference and self-administration of the NMDA receptor antagonist-benzodiazepine combination, zoletil.
Topics: Anesthetics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug In | 2013 |
Sexual identity and drug use harm among high-risk, active substance users.
Topics: Adolescent; Adult; Aged; Alcoholism; Bisexuality; British Columbia; Crack Cocaine; Cross-Sectional S | 2013 |
Circumstances of initiation into new-type drug use among adults in Shanghai: are there differences by types of first new-type drug used?
Topics: Adolescent; Adult; China; Drug Users; Female; Humans; Illicit Drugs; Ketamine; Male; Methamphetamine | 2013 |
Determination of ketamine and norketamine in hair by micropulverized extraction and liquid chromatography-high resolution mass spectrometry.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Chromatography, Liquid; Female; Forensic Toxicology; H | 2013 |
Rapid detection and quantitation of ketamine and norketamine in urine and oral fluid by wooden-tip electrospray ionization mass spectrometry.
Topics: Humans; Illicit Drugs; Ketamine; Saliva; Spectrometry, Mass, Electrospray Ionization; Substance Abus | 2013 |
Individual and combined effects of rhynchophylline and ketamine on proliferation, NMDAR1 and GluA2/3 protein expression in PC12 cells.
Topics: Animals; Carrier Proteins; Cell Proliferation; Excitatory Amino Acid Antagonists; Indole Alkaloids; | 2013 |
The neurobehavioral pharmacology of ketamine: implications for drug abuse, addiction, and psychiatric disorders.
Topics: Analgesics; Animals; Antidepressive Agents; Behavior, Addictive; Humans; Ketamine; Substance-Related | 2011 |
Patterns of use and harms associated with non-medical ketamine use.
Topics: Adult; Australia; Chi-Square Distribution; Cross-Sectional Studies; Female; Humans; Illicit Drugs; I | 2003 |
Ketamine as a preferred substance of abuse.
Topics: Adult; Anesthetics, Dissociative; Humans; Ketamine; Male; Substance-Related Disorders | 2002 |
Special K.
Topics: Adult; Anesthetics, Dissociative; Humans; Ketamine; Life Style; Male; Substance-Related Disorders | 2003 |
Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm.
Topics: Analgesics; Animals; Behavior, Animal; Conditioning, Psychological; Cyclic AMP Response Element-Bind | 2003 |
Immunomodulation by cocaine and ketamine in postnatal rats.
Topics: Adjuvants, Immunologic; Alanine Transaminase; Anesthetics, Dissociative; Animals; Animals, Newborn; | 2003 |
Profiles of urine samples from participants at rave party in Taiwan: prevalence of ketamine and MDMA abuse.
Topics: Amphetamines; Gas Chromatography-Mass Spectrometry; Humans; Ketamine; N-Methyl-3,4-methylenedioxyamp | 2003 |
Circuit parties and patterns of drug use in a subset of gay men.
Topics: Adult; Anniversaries and Special Events; Female; HIV Infections; Homosexuality, Male; Humans; Ketami | 2003 |
Drug injection practices among high-risk youths: the first shot of ketamine.
Topics: Adolescent; Adult; Female; Humans; Hygiene; Injections, Intramuscular; Ketamine; Male; New York City | 2004 |
Information from your family doctor. Club drugs--myths and risks.
Topics: Flunitrazepam; Humans; Ketamine; Leisure Activities; N-Methyl-3,4-methylenedioxyamphetamine; Sodium | 2004 |
Unprotected anal intercourse associated with recreational drug use among young men who have sex with men depends on partner type and intercourse role.
Topics: Adult; Alcohol Drinking; British Columbia; Cannabis; Cohort Studies; HIV Infections; Homosexuality, | 2004 |
Beyond the K-hole: a 3-year longitudinal investigation of the cognitive and subjective effects of ketamine in recreational users who have substantially reduced their use of the drug.
Topics: Adult; Analgesics; Case-Control Studies; Chi-Square Distribution; Female; Humans; Ketamine; Language | 2004 |
In-tube solid-phase microextraction with poly(methacrylic acid-ethylene glycol dimethacrylate) monolithic capillary for direct high-performance liquid chromatographic determination of ketamine in urine samples.
Topics: Chromatography, High Pressure Liquid; Humans; Ketamine; Polyethylene Glycols; Polymethacrylic Acids; | 2004 |
Club drugs: reasons for and consequences of use.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Dextromethorphan; Female; Flunitrazepam; Hallu | 2004 |
The rise of club drugs in a heroin society: the case of Hong Kong.
Topics: Adult; Anesthetics, Dissociative; Dancing; Focus Groups; Hallucinogens; Health Policy; Health Survey | 2005 |
Club drug use among young men who have sex with men in NYC: a preliminary epidemiological profile.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Central Nervous System Stimulants; Chronic Disease; Cr | 2005 |
Altered prefrontal dopaminergic function in chronic recreational ketamine users.
Topics: Adult; Analgesics; Benzazepines; Benzofurans; Carbon Radioisotopes; Dopamine; Female; Functional Lat | 2005 |
Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths.
Topics: Adolescent; Adult; Age of Onset; Data Collection; Demography; Female; Flunitrazepam; Humans; Inciden | 2006 |
Behavioral effects of ketamine and toxic interactions with psychostimulants.
Topics: Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Depression; Dose-Res | 2006 |
Increased risk of "club" drug use among gay and bisexual high school students in British Columbia.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Bisexuality; British Columbia; Central Nervous System | 2006 |
Differences in club drug use between heterosexual and lesbian/bisexual females.
Topics: Adolescent; Adult; Age Factors; Amphetamine-Related Disorders; Bisexuality; Cocaine-Related Disorder | 2006 |
Ketamine: a misunderstood analgesic?
Topics: Administration, Oral; Analgesics; Anesthetics, Dissociative; Drug Approval; Humans; Ketamine; Substa | 2006 |
A case of ketamine dependence with discontinuation symptoms.
Topics: Adult; Humans; Ketamine; Male; Motivation; Psychotherapy; Substance Withdrawal Syndrome; Substance-R | 2006 |
First injection of ketamine among young injection drug users (IDUs) in three U.S. cities.
Topics: Adolescent; Adult; Analgesics; Ethnicity; Female; Humans; Injections, Intramuscular; Injections, Int | 2007 |
5-Year trends in use of hallucinogens and other adjunct drugs among UK dance drug users.
Topics: Adult; Cross-Sectional Studies; Female; Hallucinogens; Humans; Incidence; Ketamine; Lysergic Acid Di | 2007 |
Polysubstance use and its correlates in adolescent ecstasy users in Taiwan.
Topics: Adolescent; Affect; Age Factors; Alcohol Drinking; Analgesics; Areca; Cross-Sectional Studies; Educa | 2007 |
Substance use and related problems: a study on the abuse of recreational and not recreational drugs in Northern Italy.
Topics: Accidents, Traffic; Adult; Alcoholism; Amphetamines; Anxiety; Crack Cocaine; Depression; Female; Hal | 2006 |
WHO Expert Committee on Drug Dependence.
Topics: 4-Butyrolactone; Advisory Committees; Azabicyclo Compounds; Buprenorphine; Butorphanol; Catha; Drona | 2006 |
Characteristics and behaviors of ketamine users in France in 2003.
Topics: Adult; Affect; Behavior, Addictive; Consciousness; Data Collection; Demography; Drug Administration | 2007 |
Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later.
Topics: Adolescent; Adult; Amnesia; Delusions; Depersonalization; Dissociative Disorders; Excitatory Amino A | 2007 |
'Street ketamine'-associated bladder dysfunction: a report of ten cases.
Topics: Adult; Female; Humans; Ketamine; Male; Substance-Related Disorders; Urinary Bladder, Neurogenic | 2007 |
High-risk behaviors and hospitalizations among gamma hydroxybutyrate (GHB) users.
Topics: Adult; Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Analgesics; Automobile Driving; Comor | 2007 |
Ketamine for the treatment of depression: what about the addictive potential?
Topics: Anesthetics, Dissociative; Depressive Disorder, Major; Humans; Infusions, Intravenous; Ketamine; Rec | 2007 |
The epidemiology of GHB and ketamine use in an Australian household survey.
Topics: Adolescent; Adult; Age Factors; Australia; Data Collection; Female; Humans; Illicit Drugs; Ketamine; | 2008 |
Attentional bias to incentive stimuli in frequent ketamine users.
Topics: Adult; Alcohol Drinking; Amphetamine; Attention; Cocaine; Educational Status; Female; Humans; Ketami | 2008 |
Trapped in the "K-hole": overview of deaths associated with ketamine misuse in the UK (1993-2006).
Topics: Adult; Anesthetics, Dissociative; Behavior, Addictive; Delusions; Female; Hallucinations; Humans; Ke | 2008 |
Impulsivity in Hong Kong-Chinese club-drug users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Asian People; Cross-Cultural Comparison; Cross-Sec | 2008 |
Journey through the K-hole: phenomenological aspects of ketamine use.
Topics: Adult; Attitude; Female; Health Status; Humans; Illicit Drugs; Ketamine; Male; Mental Disorders; Sub | 2008 |
"Research chemicals": tryptamine and phenethylamine use among high-risk youth.
Topics: Adolescent; Adult; California; Catchment Area, Health; Confusion; Cross-Sectional Studies; Diarrhea; | 2008 |
The psychotomimetic states inventory (PSI): measuring psychotic-type experiences from ketamine and cannabis.
Topics: Adolescent; Adult; Affective Symptoms; Anesthetics, Dissociative; Bipolar Disorder; Cognition Disord | 2008 |
The hallucinogens and the inhalants.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dronabinol; Halluc | 1984 |
Phencyclidine-analogue self-injection by the baboon.
Topics: Animals; Behavior, Animal; Cocaine; Humans; Injections, Intravenous; Ketamine; Male; Papio; Phencycl | 1984 |
Oral d-amphetamine and ketamine self-administration by rhesus monkeys: effects of food deprivation.
Topics: Animals; Dextroamphetamine; Food Deprivation; Humans; Ketamine; Macaca mulatta; Male; Phencyclidine; | 1983 |
Dystonic reaction after ketamine abuse.
Topics: Acute Disease; Adult; Central Nervous System Depressants; Chemical Phenomena; Chemistry; Dystonia; H | 1982 |
Long-term dangers of ketamine anaesthesia.
Topics: Anesthesia, Intravenous; Humans; Ketamine; Substance-Related Disorders; Time Factors | 1981 |
A non-invasive method of qualitative and quantitative measurement of drugs.
Topics: Alcoholic Intoxication; Cocaine; Diazepam; Electronystagmography; Ethanol; Humans; Illicit Drugs; Ke | 1981 |
Abuse of ketamine.
Topics: Adult; Humans; Ketamine; Male; Substance-Related Disorders | 1980 |
[Short term narcosis with ketamine as a substitute drug - forensic judgment of responsibility].
Topics: Adult; Forensic Medicine; Hallucinations; Humans; Ketamine; Male; Social Responsibility; Substance-R | 1980 |
A case of ketamine dependence.
Topics: Adult; Health Personnel; Humans; Ketamine; Male; Substance-Related Disorders | 1994 |
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ket | 1993 |
Non-medical use of ketamine.
Topics: Dissociative Disorders; Humans; Ketamine; Social Environment; Substance-Related Disorders | 1993 |
Non-medical use of ketamine.
Topics: Humans; Ketamine; Respiratory System; Substance-Related Disorders | 1993 |
Ecstasy and neurodegeneration. ...such as ketamine.
Topics: 3,4-Methylenedioxyamphetamine; Designer Drugs; Drug Contamination; Ephedrine; Hallucinogens; Humans; | 1996 |
Evidence of polydrug use using hair analysis: a fatal case involving heroin, cocaine, cannabis, chloroform, thiopental and ketamine.
Topics: Adult; Cannabinoids; Chloroform; Chromatography, High Pressure Liquid; Cocaine; Fatal Outcome; Femal | 1998 |
Ketamine abusers presenting to the emergency department: a case series.
Topics: Akathisia, Drug-Induced; Anesthetics, Dissociative; Anxiety; Chest Pain; Connecticut; Diagnosis, Dif | 2000 |
Cognitive, dissociative and psychotogenic effects of ketamine in recreational users on the night of drug use and 3 days later.
Topics: Adolescent; Adult; Cognition Disorders; Dissociative Disorders; Excitatory Amino Acid Antagonists; F | 2000 |
[Ketamine--a trendy doping agent in the mass media?].
Topics: Analgesics; Hallucinogens; Humans; Ketamine; Mass Media; Substance-Related Disorders | 2000 |
Ketamine in non-hospital and hospital deaths in New York City.
Topics: Adolescent; Adult; Anesthetics, Dissociative; Cause of Death; Female; Forensic Medicine; Hospital Mo | 2000 |
Raves: a review of the culture, the drugs and the prevention of harm.
Topics: Adolescent; Adult; Hallucinogens; Humans; Ketamine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Po | 2000 |
New drugs of abuse.
Topics: Age Factors; Anesthetics; Emergencies; Hallucinogens; History, 20th Century; Humans; Ketamine; N-Met | 2000 |
In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users.
Topics: Adult; Affective Symptoms; Analysis of Variance; Cognition Disorders; Educational Status; Excitatory | 2001 |
Drugs, drink'n and smok'n. Part II.
Topics: Cocaine; HIV Infections; Humans; Ketamine; Phytotherapy; Sodium Oxybate; Substance-Related Disorders | 2001 |
[New drugs at "rave parties": ketamine and prolintane].
Topics: Adolescent; Adolescent Behavior; Anesthetics, Dissociative; Central Nervous System Stimulants; Costs | 2002 |
Ketamine dependence.
Topics: Adult; Anesthetics, Dissociative; Follow-Up Studies; Humans; Ketamine; Male; Risk Assessment; Substa | 2002 |
Phencyclidine and ketamine intoxication: a study of four populations of recreational users.
Topics: Hallucinations; Humans; Ketamine; Phencyclidine; Psychoses, Substance-Induced; Substance-Related Dis | 1978 |
Progress report from the NIDA Addiction Research Center.
Topics: Animals; Decerebrate State; Disease Models, Animal; Dogs; Humans; Ketamine; Mice; Phencyclidine; Rec | 1979 |
[Cyclohexylamines: a new group of drugs threatens us].
Topics: Cyclohexylamines; Humans; Illicit Drugs; Ketamine; Phencyclidine; Substance-Related Disorders | 1979 |
Phencyclidine: angel dust.
Topics: Adolescent; Adult; Chemical Phenomena; Chemistry; Child; Gastric Lavage; Half-Life; Humans; Illicit | 1979 |
Ketamine abuse.
Topics: Adolescent; Adult; Humans; Ketamine; Substance-Related Disorders | 1979 |
Misuse of ketamine.
Topics: Humans; Ketamine; Substance-Related Disorders; Veterinary Medicine | 1992 |
Ketamine--can chronic use impair memory?
Topics: Attention; Dose-Response Relationship, Drug; Humans; Injections, Intramuscular; Injections, Intraven | 1990 |
Differences in results from in vivo and in vitro studies on the use-dependency of N-methylaspartate antagonism by MK-801 and other phencyclidine receptor ligands.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniq | 1988 |
Behavioral dependence upon phencyclidine and ketamine in the rat.
Topics: Animals; Behavior, Animal; Ketamine; Male; Phencyclidine; Rats; Rats, Inbred Strains; Substance With | 1987 |
Animal models of intravenous phencyclinoid self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Female; Infusions, Intravenous; Ket | 1987 |
Ketamine addiction.
Topics: Adult; Humans; Ketamine; Male; Substance-Related Disorders | 1987 |
Letter: Ketamine.
Topics: Adult; Female; Humans; Ketamine; Male; Nystagmus, Pathologic; Substance-Related Disorders | 1974 |
Letter: Ketamine or phencyclidine.
Topics: Humans; Ketamine; Phencyclidine; Substance-Related Disorders | 1974 |
Epilepsy or anesthesia with ketamine.
Topics: Anesthesia; Anesthetics; Animals; Cataplexy; Cats; Central Nervous System; Cyclohexanes; Depression; | 1972 |
Ketamine--"dissociative agent" or hallucinogen?
Topics: Analgesics; Cyclohexanes; Humans; Ketamine; Lysergic Acid Diethylamide; Substance-Related Disorders | 1971 |