ketamine has been researched along with Cerebral Palsy in 8 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate how effective a combination of rectally administered midazolam and racemic ketamine was for reducing pain in paediatric cerebral palsy patients receiving intramuscular injections of botulinum neurotoxin A." | 9.24 | A rectally administered combination of midazolam and ketamine was easy, effective and feasible for procedural pain in children with cerebral palsy. ( Askljung, B; Brunsson, I; Himmelmann, K; Nilsson, S; Påhlman, M, 2017) |
| "To investigate the safety and efficacy of a propofol and ketamine based sedation protocol in pediatric patients with cerebral palsy requiring BoNT-A injections." | 7.91 | Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections. ( Abu-Sultaneh, S; Abulebda, K; Louer, R; Lutfi, R; McKinney, RC, 2019) |
| " This study describes our institution's experience with ketamine-based PSA in terms of safety and efficacy in children with cerebral palsy receiving BoNT-A injections." | 7.83 | Ketamine-based procedural sedation and analgesia for botulinum toxin A injections in children with cerebral palsy. ( Choong, CT; Chow, C, 2016) |
| "The aim of this study was to investigate how effective a combination of rectally administered midazolam and racemic ketamine was for reducing pain in paediatric cerebral palsy patients receiving intramuscular injections of botulinum neurotoxin A." | 5.24 | A rectally administered combination of midazolam and ketamine was easy, effective and feasible for procedural pain in children with cerebral palsy. ( Askljung, B; Brunsson, I; Himmelmann, K; Nilsson, S; Påhlman, M, 2017) |
| "To investigate the safety and efficacy of a propofol and ketamine based sedation protocol in pediatric patients with cerebral palsy requiring BoNT-A injections." | 3.91 | Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections. ( Abu-Sultaneh, S; Abulebda, K; Louer, R; Lutfi, R; McKinney, RC, 2019) |
| " This study describes our institution's experience with ketamine-based PSA in terms of safety and efficacy in children with cerebral palsy receiving BoNT-A injections." | 3.83 | Ketamine-based procedural sedation and analgesia for botulinum toxin A injections in children with cerebral palsy. ( Choong, CT; Chow, C, 2016) |
| " Administration and dosage of ketamine preceding the stimulation of dorsal roots was determined from the anesthetic record." | 1.35 | Does ketamine affect intraoperative electrophysiological monitoring in children undergoing selective posterior rhizotomy? ( Brown, K; Farmer, JP; Frigon, C; Poulin, C; Sedeek, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Louer, R | 1 |
| McKinney, RC | 1 |
| Abu-Sultaneh, S | 1 |
| Lutfi, R | 1 |
| Abulebda, K | 1 |
| Chow, C | 1 |
| Choong, CT | 1 |
| Marta, CJ | 1 |
| Yudofsky, LM | 1 |
| Enenbach, MJ | 1 |
| Nilsson, S | 1 |
| Brunsson, I | 1 |
| Askljung, B | 1 |
| Påhlman, M | 1 |
| Himmelmann, K | 1 |
| Frigon, C | 1 |
| Sedeek, K | 1 |
| Poulin, C | 1 |
| Brown, K | 1 |
| Farmer, JP | 1 |
| Preciso, G | 1 |
| Gallo, F | 1 |
| Matarazzo, E | 1 |
| Novello, A | 1 |
| Rashiq, S | 1 |
| Guenther, C | 1 |
| Schöning, B | 1 |
| von Bazan, UB | 1 |
| Koch, H | 1 |
2 trials available for ketamine and Cerebral Palsy
| Article | Year |
|---|---|
A rectally administered combination of midazolam and ketamine was easy, effective and feasible for procedural pain in children with cerebral palsy.
Topics: Administration, Rectal; Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschoo | 2017 |
[Ketamine and diazepam for anaesthesia in infantile cerebral palsy (author's transl)].
Topics: Adolescent; Anesthesia, Intravenous; Anesthetics, Dissociative; Cerebral Palsy; Child; Child, Presch | 1974 |
6 other studies available for ketamine and Cerebral Palsy
| Article | Year |
|---|---|
Safety and Efficacy of a Propofol and Ketamine Based Procedural Sedation Protocol in Children with Cerebral Palsy Undergoing Botulinum Toxin A Injections.
Topics: Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Conscious Sedation; Female; Hospi | 2019 |
Ketamine-based procedural sedation and analgesia for botulinum toxin A injections in children with cerebral palsy.
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Conscious Sedation; F | 2016 |
Probable Ketamine-Induced Hypomanic-Like Episode in a Child With Cerebral Palsy.
Topics: Anesthetics, Dissociative; Bipolar Disorder; Cerebral Palsy; Child; Humans; Infusions, Intravenous; | 2016 |
Does ketamine affect intraoperative electrophysiological monitoring in children undergoing selective posterior rhizotomy?
Topics: Anesthetics, Intravenous; Cerebral Palsy; Child; Cohort Studies; Double-Blind Method; Electric Stimu | 2008 |
[Anesthesia problems in the orthopedic surgical treatment of children with infantile cerebral palsy].
Topics: Anesthesia, General; Arthrodesis; Cerebral Palsy; Child; Child, Preschool; Female; Humans; Infant; K | 1982 |
Dental restoration using oral ketamine.
Topics: Administration, Oral; Adult; Anesthesia, Dental; Anesthesia, General; Anesthesia, Inhalation; Anesth | 1993 |