ketamine has been researched along with Central Nervous System Diseases in 9 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia." | 8.98 | Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018) |
| "To evaluate the efficacy and safety of perioperative intravenous ketamine in adult patients when used for the treatment or prevention of acute pain following general anaesthesia." | 4.98 | Perioperative intravenous ketamine for acute postoperative pain in adults. ( Bell, RF; Brinck, EC; Heesen, M; Kontinen, V; Moore, RA; Straube, S; Tiippana, E, 2018) |
| "Increasing perfusate [Ca2+] during anoxia from zero to 4 mM resulted in progressively less recovery." | 1.28 | The pathophysiology of anoxic injury in central nervous system white matter. ( Ransom, BR; Stys, PK; Waxman, SG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brinck, EC | 1 |
| Tiippana, E | 1 |
| Heesen, M | 1 |
| Bell, RF | 1 |
| Straube, S | 1 |
| Moore, RA | 1 |
| Kontinen, V | 1 |
| Lebedev, SV | 1 |
| Volodin, NN | 1 |
| Blinov, DV | 1 |
| Lazarenko, IP | 1 |
| Rogatkin, SO | 1 |
| Chekhonin, VP | 1 |
| Köhr, G | 1 |
| Bertoldi, G | 1 |
| Manno, E | 1 |
| Bruera, G | 1 |
| Gilli, M | 1 |
| Vighetti, S | 1 |
| Ahuja, BR | 1 |
| Wiedemann, M | 1 |
| Hanke, W | 1 |
| Ransom, BR | 2 |
| Waxman, SG | 2 |
| Davis, PK | 1 |
| Stys, PK | 1 |
| Botta, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Low-dose of S-ketamine Combined With Sufentanil for Postoperative Patient-controlled Intravenous Analgesia in Patients Following Cesarean Section[NCT05299866] | Phase 4 | 216 participants (Anticipated) | Interventional | 2022-04-12 | Recruiting | ||
| Analgesic Effects of Low-dose S-ketamine in Patients Undergoing Major Spine Fusion Surgery: A Double-blinded, Randomized Controlled Trial[NCT04964219] | Phase 4 | 164 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Patient-controlled Analgesia After Scoliosis Correction Surgery: a Randomized, Double-blind, Placebo-controlled Trial[NCT04791059] | Phase 4 | 200 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| Observational Study of the Efficacy of Ketamine for Rescue Analgesia in the Post Anesthesia Recovery Room[NCT04701008] | 143 participants (Actual) | Observational | 2020-09-01 | Completed | |||
| The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283] | Phase 4 | 1,544 participants (Anticipated) | Interventional | 2021-04-12 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketamine and Central Nervous System Diseases
| Article | Year |
|---|---|
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
Perioperative intravenous ketamine for acute postoperative pain in adults.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Central Nervous System Diseases; Humans; Hyperalg | 2018 |
8 other studies available for ketamine and Central Nervous System Diseases
| Article | Year |
|---|---|
Neurological deficit and disturbances in higher nervous activity during modeling of perinatal hypoxic-ischemic damage to the central nervous system in rat pups.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Central Nervous System; Central Nervous System Diseas | 2003 |
NMDA receptor antagonists: tools in neuroscience with promise for treating CNS pathologies.
Topics: Animals; Central Nervous System Diseases; Dextromethorphan; Dizocilpine Maleate; Excitatory Amino Ac | 2007 |
[Effect of etomidate, flunitrazepam and ketamine on the brainstem auditory evoked potentials of surgical patients without audiological or neurological changes].
Topics: Brain Stem; Central Nervous System Diseases; Etomidate; Evoked Potentials, Auditory; Flunitrazepam; | 1983 |
Analgesic effect of intrathecal ketamine in rats.
Topics: Analgesia; Animals; Central Nervous System Diseases; Female; Ganglia, Spinal; Injections, Spinal; Ke | 1983 |
The chicken retina as an experimental model for investigation of central nervous lesions.
Topics: Animals; Central Nervous System Diseases; Chickens; Disease Models, Animal; Electric Stimulation; Gl | 1997 |
Anoxic injury of CNS white matter: protective effect of ketamine.
Topics: Action Potentials; Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Hypoxia; Ket | 1990 |
The pathophysiology of anoxic injury in central nervous system white matter.
Topics: Action Potentials; Animals; Calcium; Calcium Channel Blockers; Central Nervous System Diseases; Hypo | 1990 |
Anesthetic considerations for the patient with central nervous system dysfunction.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Central Nervous S | 1973 |