ketamine has been researched along with Cardiovascular Diseases in 12 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Excerpt | Relevance | Reference |
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"Ketamine is an anaesthetic and analgesic agent that demonstrates the antidepressive effect in major depression." | 9.01 | Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety. ( Cubała, WJ; Szarmach, J; Wiglusz, MS; Włodarczyk, A, 2019) |
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine." | 7.70 | Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999) |
"Ketamine is an anaesthetic and analgesic agent that demonstrates the antidepressive effect in major depression." | 5.01 | Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety. ( Cubała, WJ; Szarmach, J; Wiglusz, MS; Włodarczyk, A, 2019) |
" Patients receiving ketamine with or without midazolam experienced fewer respiratory adverse events but more vomiting than the commonly used combination of midazolam and fentanyl." | 3.73 | Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs. ( Bajaj, L; Bothner, JP; Roback, MG; Wathen, JE, 2005) |
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine." | 3.70 | Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (41.67) | 18.7374 |
1990's | 1 (8.33) | 18.2507 |
2000's | 1 (8.33) | 29.6817 |
2010's | 4 (33.33) | 24.3611 |
2020's | 1 (8.33) | 2.80 |
Authors | Studies |
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Mielke, N | 1 |
Johnson, S | 1 |
Bahl, A | 1 |
Fadladdin, YAJ | 1 |
Xue, M | 1 |
Zhang, X | 7 |
Chen, J | 3 |
Liu, F | 1 |
Xu, J | 3 |
Xie, J | 1 |
Yang, Y | 4 |
Yu, W | 1 |
Qiu, H | 1 |
Xue, J | 2 |
Jiang, J | 3 |
Liu, Y | 9 |
Shallom, SJ | 1 |
Zelazny, AM | 1 |
Giri, AR | 1 |
Kaur, N | 1 |
Yarrarapu, SNS | 1 |
Rottman Pietrzak, KA | 1 |
Santos, C | 1 |
Lowman, PE | 1 |
Niaz, S | 1 |
Franco, PM | 1 |
Sanghavi, DK | 1 |
Zhu, D | 1 |
Liang, R | 1 |
Li, Z | 4 |
Cheng, L | 1 |
Ren, J | 1 |
Guo, Y | 2 |
Wang, M | 1 |
Chai, H | 1 |
Niu, Q | 1 |
Yang, S | 2 |
Bai, J | 2 |
Yu, H | 2 |
Zhang, H | 2 |
Qin, X | 1 |
Sahrakorpi, N | 1 |
Engberg, E | 1 |
Stach-Lempinen, B | 1 |
Tammelin, TH | 1 |
Kulmala, J | 1 |
Roine, RP | 1 |
Koivusalo, SB | 1 |
Cheng, W | 1 |
Pang, H | 1 |
Campen, MJ | 1 |
Zhang, J | 5 |
Li, Y | 5 |
Gao, J | 1 |
Ren, D | 1 |
Ji, X | 1 |
Rothman, N | 1 |
Lan, Q | 1 |
Zheng, Y | 2 |
Leng, S | 1 |
Hu, Z | 2 |
Tang, J | 4 |
Dong, Q | 2 |
Song, N | 1 |
Qin, N | 1 |
Chen, C | 1 |
Sun, X | 2 |
Easton, J | 1 |
Mulder, H | 1 |
Plyler, E | 1 |
Neale, G | 1 |
Walker, E | 1 |
Li, Q | 1 |
Ma, X | 2 |
Chen, X | 4 |
Huang, IC | 1 |
Yasui, Y | 1 |
Ness, KK | 1 |
Hudson, MM | 1 |
Robison, LL | 1 |
Wang, Z | 3 |
Subota, A | 1 |
Spotswood, N | 1 |
Roach, M | 1 |
Goodarzi, Z | 1 |
Holroyd-Leduc, J | 1 |
Park, EA | 1 |
Graves, SA | 1 |
Menda, Y | 1 |
Szarmach, J | 1 |
Cubała, WJ | 1 |
Włodarczyk, A | 1 |
Wiglusz, MS | 1 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 1 |
Zhao, Y | 3 |
Wang, J | 6 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 4 |
Wang, H | 3 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 4 |
Yang, R | 1 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Zhang, Q | 4 |
Wu, X | 2 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 2 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 4 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 4 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Sun, Q | 1 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 5 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 3 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Xu, N | 1 |
Wang, R | 1 |
Liu, S | 1 |
He, H | 1 |
Dong, X | 2 |
Yang, M | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 2 |
Han, J | 2 |
Zhang, C | 3 |
Chen, L | 2 |
Yang, X | 1 |
Li, W | 3 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 4 |
Yao, L | 2 |
Sun, L | 3 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 1 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 6 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 1 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 7 |
Zhao, R | 1 |
Gu, Z | 1 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 4 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
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Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 1 |
Huang, X | 2 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Li, J | 7 |
Du, S | 1 |
Zhou, H | 1 |
Cui, J | 1 |
Wu, W | 1 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 1 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 1 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Wu, Y | 2 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 2 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
Kim, EH | 1 |
Cope, SJ | 1 |
Du, K | 1 |
Venkatesh, R | 1 |
Giardina, JD | 1 |
Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
Landfeldt, E | 1 |
Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
Gaudig, M | 1 |
Stancill, JS | 1 |
Happ, JT | 1 |
Broniowska, KA | 1 |
Hogg, N | 1 |
Corbett, JA | 1 |
Tang, LF | 1 |
Bi, YL | 1 |
Fan, Y | 2 |
Sun, YB | 1 |
Wang, AL | 1 |
Xiao, BH | 1 |
Wang, LF | 1 |
Qiu, SW | 1 |
Guo, SW | 1 |
Wáng, YXJ | 1 |
Sun, J | 2 |
Chu, S | 1 |
Pan, Q | 1 |
Li, D | 2 |
Zheng, S | 2 |
Ma, L | 1 |
Wang, L | 3 |
Hu, T | 1 |
Wang, F | 1 |
Han, Z | 1 |
Yin, Z | 1 |
Ge, X | 1 |
Xie, K | 1 |
Lei, P | 1 |
Dias-Santagata, D | 1 |
Lennerz, JK | 1 |
Sadow, PM | 1 |
Frazier, RP | 1 |
Govinda Raju, S | 1 |
Henry, D | 1 |
Chung, T | 1 |
Kherani, J | 1 |
Rothenberg, SM | 1 |
Wirth, LJ | 1 |
Marti, CN | 1 |
Choi, NG | 1 |
Bae, SJ | 1 |
Ni, L | 1 |
Luo, X | 1 |
Dai, T | 1 |
Lee, R | 1 |
Fleischer, AS | 1 |
Wemhoff, AP | 1 |
Ford, CR | 1 |
Kleppinger, EL | 1 |
Helms, K | 1 |
Bush, AA | 1 |
Luna-Abanto, J | 1 |
García Ruiz, L | 1 |
Laura Martinez, J | 1 |
Álvarez Larraondo, M | 1 |
Villoslada Terrones, V | 1 |
Dukic, L | 1 |
Maric, N | 1 |
Simundic, AM | 1 |
Chogtu, B | 1 |
Ommurugan, B | 1 |
Thomson, SR | 1 |
Kalthur, SG | 1 |
Benidir, M | 1 |
El Massoudi, S | 1 |
El Ghadraoui, L | 1 |
Lazraq, A | 1 |
Benjelloun, M | 1 |
Errachidi, F | 1 |
Cassar, M | 1 |
Law, AD | 1 |
Chow, ES | 1 |
Giebultowicz, JM | 1 |
Kretzschmar, D | 1 |
Salonurmi, T | 1 |
Nabil, H | 1 |
Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
Savolainen, MJ | 1 |
Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
Zhu, N | 1 |
Du, Q | 1 |
Hao, P | 1 |
Cao, X | 1 |
Li, CX | 1 |
Zhao, S | 1 |
Luo, XM | 1 |
Feng, JX | 1 |
Gonzalez-Cotto, M | 1 |
Guo, L | 1 |
Karwan, M | 1 |
Sen, SK | 1 |
Barb, J | 1 |
Collado, CJ | 1 |
Elloumi, F | 1 |
Palmieri, EM | 1 |
Boelte, K | 1 |
Kolodgie, FD | 1 |
Finn, AV | 1 |
Biesecker, LG | 1 |
McVicar, DW | 1 |
Qu, F | 1 |
Deng, Z | 1 |
Xie, Y | 2 |
Chen, Z | 2 |
Luo, W | 1 |
Xiong, D | 1 |
Zhao, D | 1 |
Fang, J | 1 |
Zhou, Z | 1 |
Niu, PP | 1 |
Song, B | 1 |
Xu, YM | 1 |
Zhang, Z | 2 |
Qiu, N | 1 |
Yin, J | 1 |
Guo, W | 1 |
Liu, M | 2 |
Liu, T | 2 |
Chen, D | 5 |
Luo, K | 1 |
He, Z | 2 |
Zheng, G | 1 |
Xu, F | 1 |
Sun, W | 1 |
Yin, F | 1 |
van Hest, JCM | 1 |
Du, L | 2 |
Shi, X | 1 |
Kang, S | 1 |
Duan, W | 1 |
Zhang, S | 2 |
Feng, J | 2 |
Qi, N | 1 |
Shen, G | 1 |
Ren, H | 1 |
Shang, Q | 1 |
Zhao, W | 2 |
Yang, Z | 2 |
Jiang, X | 2 |
Alame, M | 1 |
Cornillot, E | 1 |
Cacheux, V | 1 |
Tosato, G | 1 |
Four, M | 1 |
De Oliveira, L | 1 |
Gofflot, S | 1 |
Delvenne, P | 1 |
Turtoi, E | 1 |
Cabello-Aguilar, S | 1 |
Nishiyama, M | 1 |
Turtoi, A | 1 |
Costes-Martineau, V | 1 |
Colinge, J | 1 |
Guo, Q | 1 |
Quan, M | 1 |
Dong, J | 1 |
Han, R | 1 |
Cai, Y | 1 |
Lv, YQ | 1 |
Chen, Q | 1 |
Lyu, HD | 1 |
Deng, L | 1 |
Zhou, D | 1 |
Xiao, X | 1 |
De Langhe, S | 1 |
Billadeau, DD | 1 |
Lou, Z | 1 |
Zhang, JS | 1 |
Xue, Z | 1 |
Shen, XD | 1 |
Gao, F | 1 |
Busuttil, RW | 1 |
Kupiec-Weglinski, JW | 1 |
Ji, H | 1 |
Otano, I | 1 |
Alvarez, M | 1 |
Minute, L | 1 |
Ochoa, MC | 1 |
Migueliz, I | 1 |
Molina, C | 1 |
Azpilikueta, A | 1 |
de Andrea, CE | 1 |
Etxeberria, I | 1 |
Sanmamed, MF | 1 |
Teijeira, Á | 1 |
Berraondo, P | 1 |
Melero, I | 1 |
Zhong, Z | 1 |
Xie, X | 1 |
Yu, Q | 1 |
Zhou, C | 1 |
Liu, C | 2 |
Liu, W | 1 |
Chen, W | 1 |
Yin, Y | 1 |
Li, CW | 1 |
Hsu, JL | 1 |
Zhou, Q | 1 |
Hu, B | 1 |
Fu, P | 1 |
Atyah, M | 1 |
Ma, Q | 2 |
Xu, Y | 1 |
Hung, MC | 1 |
Ren, N | 1 |
Huang, P | 1 |
Liao, R | 1 |
Cao, Q | 1 |
Yuan, X | 1 |
Nie, W | 1 |
Yang, J | 2 |
Shao, B | 1 |
Bi, Z | 1 |
Liang, X | 1 |
Tie, Y | 1 |
Mo, F | 1 |
Xie, D | 1 |
Wei, Y | 1 |
Wei, X | 2 |
Dokla, EME | 1 |
Fang, CS | 1 |
Chu, PC | 1 |
Chang, CS | 1 |
Abouzid, KAM | 1 |
Chen, CS | 1 |
Blaszczyk, R | 1 |
Brzezinska, J | 1 |
Dymek, B | 1 |
Stanczak, PS | 1 |
Mazurkiewicz, M | 1 |
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Nowicka, J | 1 |
Dzwonek, K | 1 |
Zagozdzon, A | 1 |
Golab, J | 1 |
Golebiowski, A | 1 |
Xin, Z | 1 |
Himmelbauer, MK | 1 |
Jones, JH | 1 |
Enyedy, I | 1 |
Gilfillan, R | 1 |
Hesson, T | 1 |
King, K | 1 |
Marcotte, DJ | 1 |
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Santoro, JC | 1 |
Gonzalez-Lopez de Turiso, F | 1 |
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Sournia-Saquet, A | 1 |
Boutet-Robinet, E | 1 |
Destere, A | 1 |
Tronnet, A | 1 |
Bergé, J | 1 |
Bonduelle, C | 1 |
Deraeve, C | 1 |
Pratviel, G | 1 |
Stigliani, JL | 1 |
Paris, L | 1 |
Mazier, D | 1 |
Corvaisier, S | 1 |
Since, M | 1 |
Malzert-Fréon, A | 1 |
Wyllie, S | 1 |
Milne, R | 1 |
Fairlamb, AH | 1 |
Valentin, A | 1 |
Courtioux, B | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation[NCT03255824] | Phase 4 | 144 participants (Actual) | Interventional | 2018-03-20 | Completed | ||
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139] | Phase 3 | 183 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
US Guided Interscalene Block Compared With Sedation for Shoulder Dislocation Reduction in the ER[NCT03041506] | 90 participants (Anticipated) | Interventional | 2017-02-15 | Not yet recruiting | |||
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine[NCT04746079] | 180 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Surgeon satisfaction is measured by the Cooperation Scale. Minimum score of 0 and maximum of 9. Higher indicates a worse outcome (i.e., discomfort and movement) (NCT03255824)
Timeframe: 15 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 2.07 |
Dexmedetomidine Group | 1.47 |
"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline by 20% or greater will be considered clinically significant)~a. Change in blood pressure (NIBP) (change ≥ 20%) Blood pressure is presented as mean arterial pressure" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | mm Hg (Mean) |
---|---|
Propofol Group | 78 |
Dexmedetomidine Group | 88 |
"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline of both the blood pressure and heart rate by 20% or greater will be considered clinically significant)~a. Change in heart rate (change ≥ 20 BPM)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | beats per minute (Mean) |
---|---|
Propofol Group | 77 |
Dexmedetomidine Group | 62 |
"Visual Analog Scale was used to measure overall satisfaction with the IV sedation and memory of the procedure.~The minimum score is 0 (not satisfied at all) to a maximum score of 100 (completely satisfied).~A higher score is a better outcome." (NCT03255824)
Timeframe: 30 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 93.5 |
Dexmedetomidine Group | 86.6 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to ambulation (to recovery room) will be recorded" (NCT03255824)
Timeframe: After the procedure until ambulation, up to 20 minutes
Intervention | minutes (Mean) |
---|---|
Propofol Group | 10.8 |
Dexmedetomidine Group | 11.6 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Duration of procedure will be recorded" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | MINUTES (Mean) |
---|---|
Propofol Group | 24.2 |
Dexmedetomidine Group | 22.1 |
"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to discharge or virtual discharge (comparative statistic) - Aldrete score of ≥ 9 or pre-procedure score is met The minimum score is 0 and the maximum score is 10. A higher score indicates wakefulness, hemodynamically stable, and able to ambulate.~ii. All subjects are required to stay a minimum of 30 minutes after the end of the procedure. Therefore, at least two postoperative vital sign readings will be obtained. If the subject meets discharge criteria prior to 30 minutes, this time will be the virtual discharge time" (NCT03255824)
Timeframe: After the procedure until discharge, up to 45 minutes
Intervention | minutes (Mean) |
---|---|
Propofol Group | 26.5 |
Dexmedetomidine Group | 29.9 |
"To compare the groups regarding movement of the patient during the first injection of local anesthesia during the IVS at time of injection measured using the Behavioral Pain Scale - Non-Intubated patients.~The minimum value is 3 and the maximum value is 12. Higher scores mean a worse outcome (i.e., more pain and movement on injection)" (NCT03255824)
Timeframe: During the first injection of local anesthesia during surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 3.9 |
Dexmedetomidine Group | 4.2 |
"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in arterial oxygen saturation (as measured by pulse oximeter) i. number of events of ≤92%" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | Saturation percent (Mean) |
---|---|
Propofol Group | 98.7 |
Dexmedetomidine Group | 98.9 |
"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in respiratory rate (change ≥ 20%)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes
Intervention | breaths per minute (Mean) |
---|---|
Propofol Group | 18 |
Dexmedetomidine Group | 18 |
To compare the groups regarding the number of respiratory events requiring intervention, described as: Chin lift/jaw thrust, Tongue thrust, Yankauer suctioning, Positive pressure oxygen administration, Placement of an oral or nasal airway. (NCT03255824)
Timeframe: During surgery
Intervention | Participants (Count of Participants) |
---|---|
Propofol Group | 17 |
Dexmedetomidine Group | 2 |
"Surgeon satisfaction was measured by the surgeon grading the Operating Conditions scale.~The minimum value was 0 and the maximum was 3. 0=very poor, 1=poor, 2=fair, 3=good" (NCT03255824)
Timeframe: 15 minutes following surgery
Intervention | score on a scale (Mean) |
---|---|
Propofol Group | 2.8 |
Dexmedetomidine Group | 2.9 |
"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | participants (Number) |
---|---|
Ketamine Alone | 97 |
Ketamine Co-Administered With Propofol | 81 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 8 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (1-10) (Median) |
---|---|
Ketamine Alone | 10 |
Ketamine Co-Administered With Propofol | 10 |
Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour
Intervention | units on a scale (Median) |
---|---|
Ketamine Alone | 9 |
Ketamine Co-Administered With Propofol | 8 |
Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour
Intervention | minutes (Median) |
---|---|
Ketamine Alone | 44 |
Ketamine Co-Administered With Propofol | 43.5 |
We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days
Intervention | participants (Number) | |||
---|---|---|---|---|
Respiratory depression | Cardiovascular event | vomiting/retching | Unpleasant recovery reaction | |
Ketamine Alone | 12 | 1 | 21 | 4 |
Ketamine Co-Administered With Propofol | 15 | 0 | 18 | 2 |
5 reviews available for ketamine and Cardiovascular Diseases
Article | Year |
---|---|
Topics: Adult; Aging; Aluminum; Alzheimer Disease; Animals; Anti-Bacterial Agents; Artemisia annua; Body Mas | 2022 |
Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety.
Topics: Antidepressive Agents; Cardiovascular Diseases; Cardiovascular System; Depression; Depressive Disord | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Beyond evidence-based treatment of bipolar disorder: Rational pragmatic approaches to management.
Topics: Ankyrins; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disord | 2019 |
Newborn anaesthesia: pharmacological considerations.
Topics: Aging; Anesthesia; Anesthesia, Inhalation; Cardiovascular Diseases; Dose-Response Relationship, Drug | 1986 |
1 trial available for ketamine and Cardiovascular Diseases
7 other studies available for ketamine and Cardiovascular Diseases
Article | Year |
---|---|
Cardiovascular effects of ketamine in sick patients: should physicians be concerned?
Topics: Cardiovascular Diseases; Cardiovascular System; Humans; Ketamine; Physicians; Sickness Impact Profil | 2010 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S | 2005 |
[Effect of intravenous anesthesia using ketamine on respiratory and circulatory parameters].
Topics: Anesthesia, Intravenous; Animals; Cardiovascular Diseases; Dogs; Hemodynamics; Ketamine; Respiration | 1983 |
Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits.
Topics: Anesthesia; Anesthetics; Animals; Antibodies, Viral; Cardiovascular Diseases; Coronavirus; Echocardi | 1999 |
[Intravenous anesthetics as an introduction of general anesthesia in patients with complicating disease of the respiratory and circulatory systems].
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Cardiovascular Diseases; Diazepam; Flunitraz | 1979 |
[Hemodynamic changes induced by ketamine anesthesia in the very old patient].
Topics: Aged; Aged, 80 and over; Anesthesia; Anesthesia, General; Cardiovascular Diseases; Hemodynamics; Hum | 1987 |
Pharmacologic effect of a new aminoketone on the circulation.
Topics: Adolescent; Adult; Blood Circulation; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Drug | 1974 |