Page last updated: 2024-10-29

ketamine and Cardiovascular Diseases

ketamine has been researched along with Cardiovascular Diseases in 12 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research Excerpts

ExcerptRelevanceReference
"Ketamine is an anaesthetic and analgesic agent that demonstrates the antidepressive effect in major depression."9.01Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety. ( Cubała, WJ; Szarmach, J; Wiglusz, MS; Włodarczyk, A, 2019)
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine."7.70Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999)
"Ketamine is an anaesthetic and analgesic agent that demonstrates the antidepressive effect in major depression."5.01Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety. ( Cubała, WJ; Szarmach, J; Wiglusz, MS; Włodarczyk, A, 2019)
" Patients receiving ketamine with or without midazolam experienced fewer respiratory adverse events but more vomiting than the commonly used combination of midazolam and fentanyl."3.73Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs. ( Bajaj, L; Bothner, JP; Roback, MG; Wathen, JE, 2005)
"Anesthesia was induced by intramuscular administration of ketamine and xylazine followed by infusion of lactated Ringer's solution also containing ketamine and xylazine."3.70Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits. ( Dangler, C; Harpster, NK; Li, X; Marini, RP, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Mielke, N1
Johnson, S1
Bahl, A1
Fadladdin, YAJ1
Xue, M1
Zhang, X7
Chen, J3
Liu, F1
Xu, J3
Xie, J1
Yang, Y4
Yu, W1
Qiu, H1
Xue, J2
Jiang, J3
Liu, Y9
Shallom, SJ1
Zelazny, AM1
Giri, AR1
Kaur, N1
Yarrarapu, SNS1
Rottman Pietrzak, KA1
Santos, C1
Lowman, PE1
Niaz, S1
Franco, PM1
Sanghavi, DK1
Zhu, D1
Liang, R1
Li, Z4
Cheng, L1
Ren, J1
Guo, Y2
Wang, M1
Chai, H1
Niu, Q1
Yang, S2
Bai, J2
Yu, H2
Zhang, H2
Qin, X1
Sahrakorpi, N1
Engberg, E1
Stach-Lempinen, B1
Tammelin, TH1
Kulmala, J1
Roine, RP1
Koivusalo, SB1
Cheng, W1
Pang, H1
Campen, MJ1
Zhang, J5
Li, Y5
Gao, J1
Ren, D1
Ji, X1
Rothman, N1
Lan, Q1
Zheng, Y2
Leng, S1
Hu, Z2
Tang, J4
Dong, Q2
Song, N1
Qin, N1
Chen, C1
Sun, X2
Easton, J1
Mulder, H1
Plyler, E1
Neale, G1
Walker, E1
Li, Q1
Ma, X2
Chen, X4
Huang, IC1
Yasui, Y1
Ness, KK1
Hudson, MM1
Robison, LL1
Wang, Z3
Subota, A1
Spotswood, N1
Roach, M1
Goodarzi, Z1
Holroyd-Leduc, J1
Park, EA1
Graves, SA1
Menda, Y1
Szarmach, J1
Cubała, WJ1
Włodarczyk, A1
Wiglusz, MS1
Halim, AA1
Alsayed, B1
Embarak, S1
Yaseen, T1
Dabbous, S1
Fontaine, O1
Dueluzeau, R1
Raibaud, P1
Chabanet, C1
Popoff, MR1
Badoual, J1
Gabilan, JC1
Andremont, A1
Gómez, L1
Andrés, S1
Sánchez, J1
Alonso, JM1
Rey, J1
López, F1
Jiménez, A1
Yan, Z1
Zhou, L1
Zhao, Y3
Wang, J6
Huang, L2
Hu, K1
Liu, H4
Wang, H3
Guo, Z1
Song, Y1
Huang, H4
Yang, R1
Owen, TW1
Al-Kaysi, RO1
Bardeen, CJ1
Cheng, Q1
Wu, S1
Cheng, T1
Zhou, X1
Wang, B4
Zhang, Q4
Wu, X2
Yao, Y3
Ochiai, T1
Ishiguro, H2
Nakano, R2
Kubota, Y2
Hara, M1
Sunada, K1
Hashimoto, K1
Kajioka, J1
Fujishima, A1
Jiao, J3
Gai, QY3
Wang, W2
Zang, YP2
Niu, LL2
Fu, YJ3
Wang, X4
Yao, LP1
Qin, QP1
Wang, ZY1
Liu, J4
Aleksic Sabo, V1
Knezevic, P1
Borges-Argáez, R1
Chan-Balan, R1
Cetina-Montejo, L1
Ayora-Talavera, G1
Sansores-Peraza, P1
Gómez-Carballo, J1
Cáceres-Farfán, M1
Jang, J1
Akin, D1
Bashir, R1
Yu, Z1
Zhu, J2
Jiang, H1
He, C2
Xiao, Z1
Sun, Q1
Han, D1
Lei, H1
Zhao, K2
Zhu, L1
Li, X5
Fu, H2
Wilson, BK1
Step, DL1
Maxwell, CL1
Gifford, CA1
Richards, CJ1
Krehbiel, CR1
Warner, JM1
Doerr, AJ1
Erickson, GE1
Guretzky, JA1
Rasby, RJ1
Watson, AK1
Klopfenstein, TJ1
Sun, Y4
Liu, Z3
Pham, TD1
Lee, BK1
Yang, FC1
Wu, KH1
Lin, WP1
Hu, MK1
Lin, L3
Shao, J1
Sun, M1
Xu, G1
Xu, N1
Wang, R1
Liu, S1
He, H1
Dong, X2
Yang, M2
Yang, Q1
Duan, S1
Yu, Y2
Han, J2
Zhang, C3
Chen, L2
Yang, X1
Li, W3
Wang, T2
Campbell, DA1
Gao, K1
Zager, RA1
Johnson, ACM1
Guillem, A1
Keyser, J1
Singh, B1
Steubl, D1
Schneider, MP1
Meiselbach, H1
Nadal, J1
Schmid, MC1
Saritas, T1
Krane, V1
Sommerer, C1
Baid-Agrawal, S1
Voelkl, J1
Kotsis, F1
Köttgen, A1
Eckardt, KU1
Scherberich, JE1
Li, H4
Yao, L2
Sun, L3
Zhu, Z1
Naren, N1
Zhang, XX2
Gentile, GL1
Rupert, AS1
Carrasco, LI1
Garcia, EM1
Kumar, NG1
Walsh, SW1
Jefferson, KK1
Guest, RL1
Samé Guerra, D1
Wissler, M1
Grimm, J1
Silhavy, TJ1
Lee, JH2
Yoo, JS1
Kim, Y1
Kim, JS2
Lee, EJ1
Roe, JH1
Delorme, M1
Bouchard, PA1
Simon, M1
Simard, S1
Lellouche, F1
D'Urzo, KA1
Mok, F1
D'Urzo, AD1
Koneru, B1
Lopez, G1
Farooqi, A1
Conkrite, KL1
Nguyen, TH1
Macha, SJ1
Modi, A1
Rokita, JL1
Urias, E1
Hindle, A1
Davidson, H1
Mccoy, K1
Nance, J1
Yazdani, V1
Irwin, MS1
Wheeler, DA1
Maris, JM1
Diskin, SJ1
Reynolds, CP1
Abhilash, L1
Kalliyil, A1
Sheeba, V1
Hartley, AM2
Meunier, B2
Pinotsis, N1
Maréchal, A2
Xu, JY1
Genko, N1
Haraux, F1
Rich, PR1
Kamalanathan, M1
Doyle, SM1
Xu, C1
Achberger, AM1
Wade, TL1
Schwehr, K1
Santschi, PH1
Sylvan, JB1
Quigg, A1
Leong, W1
Xu, W2
Gao, S1
Zhai, X1
Wang, C2
Gilson, E1
Ye, J1
Lu, Y1
Yan, R1
Zhang, Y6
You, Q1
Cai, Q1
Yang, D1
Gu, S1
Dai, H1
Zhao, X1
Gui, C1
Gui, J1
Wu, PK1
Hong, SK1
Starenki, D1
Oshima, K1
Shao, H1
Gestwicki, JE1
Tsai, S1
Park, JI1
Wang, Y7
Zhao, R1
Gu, Z1
Dong, C2
Guo, G1
Li, L4
Barrett, HE1
Meester, EJ1
van Gaalen, K1
van der Heiden, K1
Krenning, BJ1
Beekman, FJ1
de Blois, E1
de Swart, J1
Verhagen, HJ1
Maina, T1
Nock, BA1
Norenberg, JP1
de Jong, M1
Gijsen, FJH1
Bernsen, MR1
Martínez-Milla, J1
Galán-Arriola, C1
Carnero, M1
Cobiella, J1
Pérez-Camargo, D1
Bautista-Hernández, V1
Rigol, M1
Solanes, N1
Villena-Gutierrez, R1
Lobo, M1
Mateo, J1
Vilchez-Tschischke, JP1
Salinas, B1
Cussó, L1
López, GJ1
Fuster, V1
Desco, M1
Sanchez-González, J1
Ibanez, B1
van den Berg, P1
Schweitzer, DH1
van Haard, PMM1
Geusens, PP1
van den Bergh, JP1
Zhu, X1
Huang, X2
Xu, H2
Yang, G2
Lin, Z1
Salem, HF1
Nafady, MM1
Kharshoum, RM1
Abd El-Ghafar, OA1
Farouk, HO1
Domiciano, D1
Nery, FC1
de Carvalho, PA1
Prudente, DO1
de Souza, LB1
Chalfun-Júnior, A1
Paiva, R1
Marchiori, PER1
Lu, M2
An, Z1
Li, J7
Du, S1
Zhou, H1
Cui, J1
Wu, W1
Song, J1
Lian, Q1
Uddin Ahmad, Z1
Gang, DD1
Konggidinata, MI1
Gallo, AA1
Zappi, ME1
Yang, TWW1
Johari, Y1
Burton, PR1
Earnest, A1
Shaw, K1
Hare, JL1
Brown, WA1
Kim, GA1
Han, S1
Choi, GH1
Choi, J1
Lim, YS1
Gallo, A1
Cancelli, C1
Ceron, E1
Covino, M1
Capoluongo, E1
Pocino, K1
Ianiro, G1
Cammarota, G1
Gasbarrini, A1
Montalto, M1
Somasundar, Y1
Lu, IC1
Mills, MR1
Qian, LY1
Olivares, X1
Ryabov, AD1
Collins, TJ1
Zhao, L1
Doddipatla, S1
Thomas, AM1
Nikolayev, AA1
Galimova, GR1
Azyazov, VN1
Mebel, AM1
Kaiser, RI1
Guo, S1
Yang, P1
Yu, X2
Wu, Y2
Yu, B2
Han, B1
George, MW1
Moor, MB1
Bonny, O1
Langenberg, E1
Paik, H1
Smith, EH1
Nair, HP1
Hanke, I1
Ganschow, S1
Catalan, G1
Domingo, N1
Schlom, DG1
Assefa, MK1
Wu, G2
Hayton, TW1
Becker, B1
Enikeev, D1
Netsch, C1
Gross, AJ1
Laukhtina, E1
Glybochko, P1
Rapoport, L1
Herrmann, TRW1
Taratkin, M1
Dai, W1
Shi, J2
Carreno, J1
Kloner, RA1
Pickersgill, NA1
Vetter, JM1
Kim, EH1
Cope, SJ1
Du, K1
Venkatesh, R1
Giardina, JD1
Saad, NES1
Bhayani, SB1
Figenshau, RS1
Eriksson, J1
Landfeldt, E1
Ireland, S1
Jackson, C1
Wyatt, E1
Gaudig, M1
Stancill, JS1
Happ, JT1
Broniowska, KA1
Hogg, N1
Corbett, JA1
Tang, LF1
Bi, YL1
Fan, Y2
Sun, YB1
Wang, AL1
Xiao, BH1
Wang, LF1
Qiu, SW1
Guo, SW1
Wáng, YXJ1
Sun, J2
Chu, S1
Pan, Q1
Li, D2
Zheng, S2
Ma, L1
Wang, L3
Hu, T1
Wang, F1
Han, Z1
Yin, Z1
Ge, X1
Xie, K1
Lei, P1
Dias-Santagata, D1
Lennerz, JK1
Sadow, PM1
Frazier, RP1
Govinda Raju, S1
Henry, D1
Chung, T1
Kherani, J1
Rothenberg, SM1
Wirth, LJ1
Marti, CN1
Choi, NG1
Bae, SJ1
Ni, L1
Luo, X1
Dai, T1
Lee, R1
Fleischer, AS1
Wemhoff, AP1
Ford, CR1
Kleppinger, EL1
Helms, K1
Bush, AA1
Luna-Abanto, J1
García Ruiz, L1
Laura Martinez, J1
Álvarez Larraondo, M1
Villoslada Terrones, V1
Dukic, L1
Maric, N1
Simundic, AM1
Chogtu, B1
Ommurugan, B1
Thomson, SR1
Kalthur, SG1
Benidir, M1
El Massoudi, S1
El Ghadraoui, L1
Lazraq, A1
Benjelloun, M1
Errachidi, F1
Cassar, M1
Law, AD1
Chow, ES1
Giebultowicz, JM1
Kretzschmar, D1
Salonurmi, T1
Nabil, H1
Ronkainen, J1
Hyötyläinen, T1
Hautajärvi, H1
Savolainen, MJ1
Tolonen, A1
Orešič, M1
Känsäkoski, P1
Rysä, J1
Hakkola, J1
Hukkanen, J1
Zhu, N1
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Hao, P1
Cao, X1
Li, CX1
Zhao, S1
Luo, XM1
Feng, JX1
Gonzalez-Cotto, M1
Guo, L1
Karwan, M1
Sen, SK1
Barb, J1
Collado, CJ1
Elloumi, F1
Palmieri, EM1
Boelte, K1
Kolodgie, FD1
Finn, AV1
Biesecker, LG1
McVicar, DW1
Qu, F1
Deng, Z1
Xie, Y2
Chen, Z2
Luo, W1
Xiong, D1
Zhao, D1
Fang, J1
Zhou, Z1
Niu, PP1
Song, B1
Xu, YM1
Zhang, Z2
Qiu, N1
Yin, J1
Guo, W1
Liu, M2
Liu, T2
Chen, D5
Luo, K1
He, Z2
Zheng, G1
Xu, F1
Sun, W1
Yin, F1
van Hest, JCM1
Du, L2
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Kang, S1
Duan, W1
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Feng, J2
Qi, N1
Shen, G1
Ren, H1
Shang, Q1
Zhao, W2
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Jiang, X2
Alame, M1
Cornillot, E1
Cacheux, V1
Tosato, G1
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De Oliveira, L1
Gofflot, S1
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Turtoi, A1
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Billadeau, DD1
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Xue, Z1
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Kupiec-Weglinski, JW1
Ji, H1
Otano, I1
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Minute, L1
Ochoa, MC1
Migueliz, I1
Molina, C1
Azpilikueta, A1
de Andrea, CE1
Etxeberria, I1
Sanmamed, MF1
Teijeira, Á1
Berraondo, P1
Melero, I1
Zhong, Z1
Xie, X1
Yu, Q1
Zhou, C1
Liu, C2
Liu, W1
Chen, W1
Yin, Y1
Li, CW1
Hsu, JL1
Zhou, Q1
Hu, B1
Fu, P1
Atyah, M1
Ma, Q2
Xu, Y1
Hung, MC1
Ren, N1
Huang, P1
Liao, R1
Cao, Q1
Yuan, X1
Nie, W1
Yang, J2
Shao, B1
Bi, Z1
Liang, X1
Tie, Y1
Mo, F1
Xie, D1
Wei, Y1
Wei, X2
Dokla, EME1
Fang, CS1
Chu, PC1
Chang, CS1
Abouzid, KAM1
Chen, CS1
Blaszczyk, R1
Brzezinska, J1
Dymek, B1
Stanczak, PS1
Mazurkiewicz, M1
Olczak, J1
Nowicka, J1
Dzwonek, K1
Zagozdzon, A1
Golab, J1
Golebiowski, A1
Xin, Z1
Himmelbauer, MK1
Jones, JH1
Enyedy, I1
Gilfillan, R1
Hesson, T1
King, K1
Marcotte, DJ1
Murugan, P1
Santoro, JC1
Gonzalez-Lopez de Turiso, F1
Pedron, J1
Boudot, C1
Brossas, JY1
Pinault, E1
Bourgeade-Delmas, S1
Sournia-Saquet, A1
Boutet-Robinet, E1
Destere, A1
Tronnet, A1
Bergé, J1
Bonduelle, C1
Deraeve, C1
Pratviel, G1
Stigliani, JL1
Paris, L1
Mazier, D1
Corvaisier, S1
Since, M1
Malzert-Fréon, A1
Wyllie, S1
Milne, R1
Fairlamb, AH1
Valentin, A1
Courtioux, B1
Verhaeghe, P1
Fang, X1
Gao, M1
Gao, H1
Bi, W1
Tang, H1
Cui, Y1
Zhang, L3
Fan, H1
Mathison, CJN1
Chianelli, D1
Rucker, PV1
Nelson, J1
Roland, J1
Huang, Z2
Xie, YF1
Epple, R1
Bursulaya, B1
Lee, C1
Gao, MY1
Shaffer, J1
Briones, S1
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Galkin, A1
Li, N1
Li, C2
Hua, S1
Kasibhatla, S1
Kinyamu-Akunda, J1
Kikkawa, R1
Molteni, V1
Tellew, JE1
Jin, X1
Pang, B1
Liu, Q2
Liu, X3
Huang, Y2
Josephine Fauci, A1
Ma, Y1
Soo Lee, M1
Yuan, W1
Gao, R1
Qi, H1
Zheng, W1
Yang, F2
Chua, H1
Wang, K1
Ou, Y1
Huang, M1
Zhu, Y1
Yu, J1
Tian, J1
Zhao, M1
Hu, J1
Yao, C1
Zhang, B1
Usawachintachit, M1
Tzou, DT1
Washington, SL1
Hu, W1
Chi, T1
Sorensen, MD1
Bailey, MR1
Hsi, RS1
Cunitz, BW1
Simon, J1
Wang, YN1
Dunmire, BL1
Paun, M1
Starr, F1
Lu, W1
Evan, AP1
Harper, JD1
Han, G1
Rodrigues, AE1
Fouladvand, F1
Falahi, E1
Asbaghi, O1
Abbasnezhad, A1
Anigboro, AA1
Avwioroko, OJ1
Cholu, CO1
Sonei, A1
Fazelipour, S1
Kanaani, L1
Jahromy, MH1
Jo, K1
Hong, KB1
Suh, HJ1
Park, JH1
Shin, E1
Park, E1
Kouakou-Kouamé, CA1
N'guessan, FK1
Montet, D1
Djè, MK1
Kim, GD1
González-Fernández, D1
Pons, EDC1
Rueda, D1
Sinisterra, OT1
Murillo, E1
Scott, ME1
Koski, KG1
Shete, PB1
Gonzales, R1
Ackerman, S1
Cattamanchi, A1
Handley, MA1
Li, XX1
Xiao, SZ1
Gu, FF1
He, WP1
Ni, YX1
Han, LZ1
Heffernan, JK1
Valgepea, K1
de Souza Pinto Lemgruber, R1
Casini, I1
Plan, M1
Tappel, R1
Simpson, SD1
Köpke, M1
Nielsen, LK1
Marcellin, E1
Cen, YK1
Lin, JG1
Wang, YL1
Wang, JY1
Liu, ZQ1
Zheng, YG1
Spirk, D1
Noll, S1
Burnier, M1
Rimoldi, S1
Noll, G1
Sudano, I1
Penzhorn, BL1
Oosthuizen, MC1
Kobos, LM1
Alqatani, S1
Ferreira, CR1
Aryal, UK1
Hedrick, V1
Sobreira, TJP1
Shannahan, JH1
Gale, P1
Singhroy, DN1
MacLean, E1
Kohli, M1
Lessem, E1
Branigan, D1
England, K1
Suleiman, K1
Drain, PK1
Ruhwald, M1
Schumacher, S1
Denkinger, CM1
Waning, B1
Van Gemert, W1
Pai, M1
Myers, RK1
Bonsu, JM1
Carey, ME1
Yerys, BE1
Mollen, CJ1
Curry, AE1
Douglas, TA1
Alinezhadbalalami, N1
Balani, N1
Schmelz, EM1
Davalos, RV1
Kamaldinov, T1
Erndt-Marino, J1
Levin, M1
Kaplan, DL1
Hahn, MS1
Heidarimoghadam, R1
Farmany, A1
Lee, JJ1
Kang, J1
Park, S1
Cho, JH1
Oh, S1
Park, DJ1
Perez-Maldonado, R1
Cho, JY1
Park, IH1
Kim, HB1
Song, M1
Mfarrej, B1
Jofra, T1
Morsiani, C1
Gagliani, N1
Fousteri, G1
Battaglia, M1
Giuliano, C1
Levinger, I1
Vogrin, S1
Neil, CJ1
Allen, JD1
Lv, Y1
Yuan, R1
Cai, B1
Bahrami, B1
Chowdhury, AH1
Yang, C2
Qiao, Q1
Liu, SF1
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Mahalapbutr, P1
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Luo, J1
Ye, S1
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Nigam, K1
Srivastava, S1
Tyagi, A1
Dang, S1
Millar, JE1
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Passmore, MR1
Obonyo, NG1
Malfertheiner, MV1
von Bahr, V1
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Ki, KK1
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Boyle, AJ1
Baillie, JK1
Shekar, K1
Palpant, N1
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McAuley, DF1
Fraser, JF1
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Gerety, GF1
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Child, CJ1
Oh, BL1
Lee, JS1
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Lee, HY1
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Leslie, I1
Boos, LA1
Larkin, J1
Pickering, L1
Lima, HK1
Vogel, K1
Hampel, D1
Wagner-Gillespie, M1
Fogleman, AD1
Ferraz, SL1
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Mazzucchelli, TG1
Kajiyama, H1
Suzuki, S1
Shimbo, A1
Utsumi, F1
Yoshikawa, N1
Kikkawa, F1
Javvaji, PK1
Dhali, A1
Francis, JR1
Kolte, AP1
Roy, SC1
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Mech, A1
Sejian, V1
DeSilva, S1
Vaidya, SS1
Mao, C1
Akhatayeva, Z1
Cheng, H1
Zhang, G1
Jiang, F1
Meng, X1
Elnour, IE1
Lan, X1
Song, E1
Rohde, S1
Antonides, CFJ1
Muslem, R1
de Woestijne, PCV1
der Meulen, MHV1
Kraemer, US1
Dalinghaus, M1
Bogers, AJJC1
Pourmand, A1
Ghassemi, M1
Sumon, K1
Amini, SB1
Hood, C1
Sikka, N1
Duan, H1
Chen, WP1
Fan, M1
Wang, WP1
Yu, L1
Tan, SJ1
Xin, S1
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Guo, YG1
Tanda, S1
Gingl, K1
Ličbinský, R1
Hegrová, J1
Goessler, W1
Li, ZL1
Zhou, YL1
Yan, W1
Luo, L1
Su, ZZ1
Fan, MZ1
Wang, SR1
Zhao, WG1
Xu, D1
Hassan, HM1
Jiang, Z1
Bachmann, KF1
Haenggi, M1
Jakob, SM1
Takala, J1
Gattinoni, L1
Berger, D1
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Vecchiarelli, E1
Banks, L1
Gonçalves, PEO1
Thomas, SG1
Goodman, JM1
Mather, K1
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Panahi, S1
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Hu, BC1
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Chu, Q1
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Lu, X1
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Wang, HY1
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Shasha, Y1
Jincai, W1
Chunyan, L1
Mengya, Y1
Yongli, S1
Rasoanirina, BNV1
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Tang, SJ1
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Peng, M1
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Liao, CX1
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Cao, WH1
Lyu, J1
Yu, CQ1
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Pang, ZC1
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Dong, Z1
Wu, F1
Wu, XP1
Jiang, GH1
Wang, XJ1
Wang, BY1
Li, LM1
Pan, L1
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Shan, GL1
Weng, TT1
Yan, SQ1
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Tao, FB1
Shao, ZH1
Yao, T1
Dong, S1
Shi, S1
Feng, YL1
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Wang, SP1
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Operario, D1
Zhang, ZH1
Zhu, XF1
Zaller, N1
Gao, P1
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Lippmann, M1
Karnwal, A1
Julka, IS1
Roback, MG1
Wathen, JE1
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Gudushauri, ON1
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Lebanidze, NG1
Marini, RP1
Harpster, NK1
Dangler, C1
Navrátilová, A1
Varmuzková, J1
Cundrle, I1
Cook, DR1
Maneglia, R1
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Gallais, Y1
Cousin, MT1
Káldor, A1
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Somogyi, G1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation[NCT03255824]Phase 4144 participants (Actual)Interventional2018-03-20Completed
Comparison of Ketamine Versus Co-Administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department[NCT01387139]Phase 3183 participants (Actual)Interventional2011-01-31Completed
US Guided Interscalene Block Compared With Sedation for Shoulder Dislocation Reduction in the ER[NCT03041506]90 participants (Anticipated)Interventional2017-02-15Not yet recruiting
Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine[NCT04746079]180 participants (Anticipated)Interventional2021-02-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cooperation Scale

Surgeon satisfaction is measured by the Cooperation Scale. Minimum score of 0 and maximum of 9. Higher indicates a worse outcome (i.e., discomfort and movement) (NCT03255824)
Timeframe: 15 minutes following surgery

Interventionscore on a scale (Mean)
Propofol Group2.07
Dexmedetomidine Group1.47

Hemodynamic Stability - Blood Pressure

"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline by 20% or greater will be considered clinically significant)~a. Change in blood pressure (NIBP) (change ≥ 20%) Blood pressure is presented as mean arterial pressure" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes

Interventionmm Hg (Mean)
Propofol Group78
Dexmedetomidine Group88

Hemodynamic Stability - Heart Rate

"To compare the differences in hemodynamic stability using a D/M combination compared to the MFP combination. (In this study, a deviation from baseline of both the blood pressure and heart rate by 20% or greater will be considered clinically significant)~a. Change in heart rate (change ≥ 20 BPM)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes

Interventionbeats per minute (Mean)
Propofol Group77
Dexmedetomidine Group62

Patient Satisfaction

"Visual Analog Scale was used to measure overall satisfaction with the IV sedation and memory of the procedure.~The minimum score is 0 (not satisfied at all) to a maximum score of 100 (completely satisfied).~A higher score is a better outcome." (NCT03255824)
Timeframe: 30 minutes following surgery

Interventionscore on a scale (Mean)
Propofol Group93.5
Dexmedetomidine Group86.6

Postoperative Recovery Time - Ambulation

"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to ambulation (to recovery room) will be recorded" (NCT03255824)
Timeframe: After the procedure until ambulation, up to 20 minutes

Interventionminutes (Mean)
Propofol Group10.8
Dexmedetomidine Group11.6

Postoperative Recovery Time - Duration of Procedure

"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Duration of procedure will be recorded" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes

InterventionMINUTES (Mean)
Propofol Group24.2
Dexmedetomidine Group22.1

Postoperative Recovery Time - Time to Discharge

"To assess whether a D/M combination increases postoperative recovery time when compared the MFP combination.~a. Time to discharge or virtual discharge (comparative statistic) - Aldrete score of ≥ 9 or pre-procedure score is met The minimum score is 0 and the maximum score is 10. A higher score indicates wakefulness, hemodynamically stable, and able to ambulate.~ii. All subjects are required to stay a minimum of 30 minutes after the end of the procedure. Therefore, at least two postoperative vital sign readings will be obtained. If the subject meets discharge criteria prior to 30 minutes, this time will be the virtual discharge time" (NCT03255824)
Timeframe: After the procedure until discharge, up to 45 minutes

Interventionminutes (Mean)
Propofol Group26.5
Dexmedetomidine Group29.9

Reaction to Administration of Local Anesthesia

"To compare the groups regarding movement of the patient during the first injection of local anesthesia during the IVS at time of injection measured using the Behavioral Pain Scale - Non-Intubated patients.~The minimum value is 3 and the maximum value is 12. Higher scores mean a worse outcome (i.e., more pain and movement on injection)" (NCT03255824)
Timeframe: During the first injection of local anesthesia during surgery

Interventionscore on a scale (Mean)
Propofol Group3.9
Dexmedetomidine Group4.2

Respiratory Depression - Oxygen Saturation

"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in arterial oxygen saturation (as measured by pulse oximeter) i. number of events of ≤92%" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes

InterventionSaturation percent (Mean)
Propofol Group98.7
Dexmedetomidine Group98.9

Respiratory Depression - Respiratory Rate

"To assess whether a D/M combination leads to a significant change in respiratory depression compared to the MFP combination.~a. Change in respiratory rate (change ≥ 20%)" (NCT03255824)
Timeframe: During the procedure, up to 40 minutes

Interventionbreaths per minute (Mean)
Propofol Group18
Dexmedetomidine Group18

Respiratory Events Requiring Intervention

To compare the groups regarding the number of respiratory events requiring intervention, described as: Chin lift/jaw thrust, Tongue thrust, Yankauer suctioning, Positive pressure oxygen administration, Placement of an oral or nasal airway. (NCT03255824)
Timeframe: During surgery

InterventionParticipants (Count of Participants)
Propofol Group17
Dexmedetomidine Group2

Surgeon Satisfaction - Survey

"Surgeon satisfaction was measured by the surgeon grading the Operating Conditions scale.~The minimum value was 0 and the maximum was 3. 0=very poor, 1=poor, 2=fair, 3=good" (NCT03255824)
Timeframe: 15 minutes following surgery

Interventionscore on a scale (Mean)
Propofol Group2.8
Dexmedetomidine Group2.9

Efficacy of Sedation

"Efficacy is defined as:~The patient does not have unpleasant recall of the procedure.~The patient did not experience sedation-related adverse events resulting in abandonment of the procedure or a permanent complication or an unplanned admission to the hospital or prolonged emergency department (ED) observation~The patient did not actively resist or require physical restraint for completion of the procedure. The need for minimal redirection of movements should not be considered as active resistance or physical restraint.~The procedure was successful" (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionparticipants (Number)
Ketamine Alone97
Ketamine Co-Administered With Propofol81

Nurse Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (Median)
Ketamine Alone10
Ketamine Co-Administered With Propofol8

Parent Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (1-10) (Median)
Ketamine Alone10
Ketamine Co-Administered With Propofol10

Physician Performing Procedure Satisfaction

Measured on a 10-point scale (1= least satisfied, 10= most satisfied) (NCT01387139)
Timeframe: After procedure is completed, on average less than 1 hour

Interventionunits on a scale (Median)
Ketamine Alone9
Ketamine Co-Administered With Propofol8

Recovery Time

Time until the patient has a Vancouver Sedation Recovery Scale Score of 18 or greater. (NCT01387139)
Timeframe: Once Vancouver Sedation Recovery Scale Score reaches 18 or greater, on average less than 1 hour

Interventionminutes (Median)
Ketamine Alone44
Ketamine Co-Administered With Propofol43.5

Frequency of Adverse Events

We will record all adverse events during the sedation, and then perform a follow-up call to determine if any additional adverse events occured after discharge. (NCT01387139)
Timeframe: From enrollment through completion of follow-up, up to 7 days

,
Interventionparticipants (Number)
Respiratory depressionCardiovascular eventvomiting/retchingUnpleasant recovery reaction
Ketamine Alone121214
Ketamine Co-Administered With Propofol150182

Reviews

5 reviews available for ketamine and Cardiovascular Diseases

ArticleYear
    Lancet regional health. Americas, 2022, Volume: 8

    Topics: Adult; Aging; Aluminum; Alzheimer Disease; Animals; Anti-Bacterial Agents; Artemisia annua; Body Mas

2022
Short-term ketamine administration in treatment-resistant depression: focus on cardiovascular safety.
    Psychiatria Danubina, 2019, Volume: 31, Issue:Suppl 3

    Topics: Antidepressive Agents; Cardiovascular Diseases; Cardiovascular System; Depression; Depressive Disord

2019
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Beyond evidence-based treatment of bipolar disorder: Rational pragmatic approaches to management.
    Bipolar disorders, 2019, Volume: 21, Issue:7

    Topics: Ankyrins; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Bipolar Disord

2019
Newborn anaesthesia: pharmacological considerations.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2

    Topics: Aging; Anesthesia; Anesthesia, Inhalation; Cardiovascular Diseases; Dose-Response Relationship, Drug

1986

Trials

1 trial available for ketamine and Cardiovascular Diseases

ArticleYear
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016

Other Studies

7 other studies available for ketamine and Cardiovascular Diseases

ArticleYear
Cardiovascular effects of ketamine in sick patients: should physicians be concerned?
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:4

    Topics: Cardiovascular Diseases; Cardiovascular System; Humans; Ketamine; Physicians; Sickness Impact Profil

2010
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
Adverse events associated with procedural sedation and analgesia in a pediatric emergency department: a comparison of common parenteral drugs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics; Cardiovascular Diseases; Child; Child, Preschool; Cohort S

2005
[Effect of intravenous anesthesia using ketamine on respiratory and circulatory parameters].
    Vestnik khirurgii imeni I. I. Grekova, 1983, Volume: 131, Issue:8

    Topics: Anesthesia, Intravenous; Animals; Cardiovascular Diseases; Dogs; Hemodynamics; Ketamine; Respiration

1983
Cardiovascular pathology possibly associated with ketamine/xylazine anesthesia in Dutch belted rabbits.
    Laboratory animal science, 1999, Volume: 49, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Antibodies, Viral; Cardiovascular Diseases; Coronavirus; Echocardi

1999
[Intravenous anesthetics as an introduction of general anesthesia in patients with complicating disease of the respiratory and circulatory systems].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1979, Volume: 58, Issue:1

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Cardiovascular Diseases; Diazepam; Flunitraz

1979
[Hemodynamic changes induced by ketamine anesthesia in the very old patient].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1987, Volume: 28, Issue:8

    Topics: Aged; Aged, 80 and over; Anesthesia; Anesthesia, General; Cardiovascular Diseases; Hemodynamics; Hum

1987
Pharmacologic effect of a new aminoketone on the circulation.
    Therapia Hungarica (English edition), 1974, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Blood Circulation; Blood Pressure; Cardiac Output; Cardiovascular Diseases; Drug

1974