Page last updated: 2024-10-29

ketamine and Cardiomyopathies

ketamine has been researched along with Cardiomyopathies in 8 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).

Research Excerpts

ExcerptRelevanceReference
"Report a case of central diabetes insipidus (DI) associated with ketamine infusion."7.80Transient central diabetes insipidus induced by ketamine infusion. ( Felner, EI; Hatab, SZ; Kamat, P; Singh, A, 2014)
"Report a case of central diabetes insipidus (DI) associated with ketamine infusion."3.80Transient central diabetes insipidus induced by ketamine infusion. ( Felner, EI; Hatab, SZ; Kamat, P; Singh, A, 2014)
" Although its toxicity on the central nervous system (CNS) and urinary system had been reported, its potential adverse effects on the heart is still not addressed."1.37Cardiotoxicity induced in mice by long term ketamine and ketamine plus alcohol treatment. ( Chan, WM; Hung, AS; Liang, Y; Wai, MS; Yew, DT, 2011)
" Therefore, we tested the dose-response direct cardiac effects of clinically available induction agents in an isolated septic rat heart model."1.35Cardiac effects of induction agents in the septic rat heart. ( Busse, H; Graf, BM; Lunz, D; Sinner, B; Zausig, YA; Zink, W, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hatab, SZ1
Singh, A1
Felner, EI1
Kamat, P1
Zausig, YA1
Busse, H1
Lunz, D1
Sinner, B1
Zink, W1
Graf, BM1
Acar, HV1
Cuvaş, O1
Ceyhan, A1
Yücel, F1
Dikmen, B1
Chan, WM1
Liang, Y1
Wai, MS1
Hung, AS1
Yew, DT1
Akkerdaas, LC1
Mioch, P1
Sap, R1
Hellebrekers, LJ1
Glisson, SN1
Gutzke, GE1
Pifarre, R1
Rao, TL1
Riou, B1
Viars, P1
Lecarpentier, Y1
Brockmüller, KD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Prevention of Post Operative Cognitive Dysfunction by Ketamine: a Prospective Multicenter Randomized Blinded Placebo-controlled Trial in Elderly Patients Undergoing Elective Orthopaedic Surgery[NCT02892916]Phase 3307 participants (Actual)Interventional2017-03-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ketamine and Cardiomyopathies

ArticleYear
Cardiopulmonary effects of three different anaesthesia protocols in cats.
    The veterinary quarterly, 2001, Volume: 23, Issue:4

    Topics: Acepromazine; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthe

2001

Other Studies

7 other studies available for ketamine and Cardiomyopathies

ArticleYear
Transient central diabetes insipidus induced by ketamine infusion.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Anesthetics; Cardiomyopathies; Cardiomyopathy, Hypertrophic; Child

2014
Cardiac effects of induction agents in the septic rat heart.
    Critical care (London, England), 2009, Volume: 13, Issue:5

    Topics: Analgesics; Anesthetics, Intravenous; Animals; Cardiomyopathies; Dose-Response Relationship, Drug; G

2009
Ketamine-midazolam anesthesia for an infant with arthrogryposis multiplex congenita: a case with decreased myocardial contractility.
    Journal of anesthesia, 2011, Volume: 25, Issue:5

    Topics: Anesthesia, General; Arthrogryposis; Cardiomyopathies; Female; Humans; Infant; Ketamine; Midazolam

2011
Cardiotoxicity induced in mice by long term ketamine and ketamine plus alcohol treatment.
    Toxicology letters, 2011, Nov-30, Volume: 207, Issue:2

    Topics: Animals; Cardiomyopathies; Cardiotoxins; Drug Synergism; Electrocardiography; Ethanol; Heart; Ketami

2011
Atrial natriuretic peptide responses during anaesthesia in patients with refractory cardiomyopathies.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:5

    Topics: Adult; Anesthesia, Intravenous; Anesthetics; Atrial Function, Right; Atrial Natriuretic Factor; Bloo

1991
Effects of ketamine on the cardiac papillary muscle of normal hamsters and those with cardiomyopathy.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Animals; Biomechanical Phenomena; Cardiomyopathies; Cricetinae; In Vitro Techniques; Ketamine; Mesoc

1990
[Anesthesia with ketamines in surgery of the mouth, the jaw and the face].
    Deutsche zahnarztliche Zeitschrift, 1971, Volume: 26, Issue:10

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Anesthetics; Blood Pressure; Cardiac Out

1971