ketamine has been researched along with Carcinoma, Epidermoid in 6 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hakim, RC | 1 |
| Edmonds, KP | 1 |
| Atayee, RS | 1 |
| Slatkin, NE | 1 |
| Rhiner, M | 1 |
| Bley, CR | 1 |
| Roos, M | 1 |
| Price, J | 1 |
| Ruess-Melzer, K | 1 |
| Buchholz, J | 1 |
| Poirier, V | 1 |
| Kaser-Hotz, B | 1 |
| Clark, JL | 1 |
| Kalan, GE | 1 |
| Urano, M | 1 |
| Chen, Y | 1 |
| Humm, J | 1 |
| Koutcher, JA | 1 |
| Zanzonico, P | 1 |
| Ling, C | 1 |
| Bryant, WM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash[NCT01566448] | Phase 2 | 30 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| Study of the Efficiency of the Ketamine With Low Analgesic Doses, in Association With High Opioids, in the Treatment of the Rebels Pains, in Palliative Phase of the Cancerous Disease[NCT01326325] | Phase 3 | 24 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417] | Phase 2 | 120 participants (Anticipated) | Interventional | 2022-05-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in pain score as reported at baseline and after the use of ketamine mouthwash on a numeric scale from 0 to 10, with 0 representing no pain and 10 representing the worst pain. (NCT01566448)
Timeframe: 1 hour after baseline
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 2 |
Sleep quality, as reported by the subject on a numeric scale (1-10) will be used as a surrogate marker of quality of life with 0 indicating no sleep and 10 indicating the best sleep you have had. (NCT01566448)
Timeframe: Day 1 after start of ketamine mouthwashes
| Intervention | score on a scale (Median) |
|---|---|
| Ketamine | 1 |
Change of topical lidocaine uses in 24 hour period (NCT01566448)
Timeframe: Days 1 after start of ketamine mouthwashes
| Intervention | lidocaine doses per day (Median) |
|---|---|
| Ketamine | 1 |
Change in IV morphine equivalents of opioid requirements (NCT01566448)
Timeframe: Days 1 after start of ketamine mouthwashes
| Intervention | IV morphine equivalents (Median) |
|---|---|
| Ketamine | 12 |
6 other studies available for ketamine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Case Report: Utility of Ketamine, Lidocaine, and Mexiletine as Nonopioid Adjuvants in Complex Cancer-Associated Pain.
Topics: Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Carcinoma, Squamous Cell; Fe | 2018 |
Topical ketamine in the treatment of mucositis pain.
Topics: Adult; Analgesics; Carcinoma, Squamous Cell; Excitatory Amino Acid Antagonists; Female; Humans; Keta | 2003 |
Clinical assessment of repeated propofol-associated anesthesia in cats.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Pressure; Carcinoma, Squamous Cell | 2007 |
Effective treatment of severe cancer pain of the head using low-dose ketamine in an opioid-tolerant patient.
Topics: Adult; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Ketamine; | 1995 |
Effective treatment of severe cancer pain of the head using low-dose ketamine in an opioid-tolerant patient.
Topics: Adult; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Ketamine; | 1995 |
Effective treatment of severe cancer pain of the head using low-dose ketamine in an opioid-tolerant patient.
Topics: Adult; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Ketamine; | 1995 |
Effective treatment of severe cancer pain of the head using low-dose ketamine in an opioid-tolerant patient.
Topics: Adult; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Ketamine; | 1995 |
Measurements of tumor tissue oxygen tension using a time-resolved luminescence-based optical oxylite probe: comparison with a paired survival assay.
Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Survival; Fibrosarcoma; Humans; Ketamine; Mice | 2002 |
Ketamine anesthesia and intranasal or intraoral operations. A potentially dangerous combination.
Topics: Adolescent; Adult; Aged; Airway Obstruction; Anesthesia, Intravenous; Carcinoma, Squamous Cell; Coug | 1973 |