ketamine has been researched along with Brain Swelling in 13 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of ketamine pretreatment on cerebral edema following brain ischemia reperfusion injury in rats and assess the involvement of Aquaporin 4 (AQP4) expression." | 7.76 | [The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats]. ( Cai, SN; Zhu, SM, 2010) |
| " Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)." | 5.17 | Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013) |
| "To investigate the effects of ketamine pretreatment on cerebral edema following brain ischemia reperfusion injury in rats and assess the involvement of Aquaporin 4 (AQP4) expression." | 3.76 | [The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats]. ( Cai, SN; Zhu, SM, 2010) |
| "TBI caused cerebral edema and increased concentrations of cerebral IL-1α, IL-1β, IL-6, IL-10, and tumor necrosis factor-α." | 1.37 | Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat. ( Cox, CS; Harting, MT; Mercer, DW; Ward, JL, 2011) |
| "In the other 15 cats, cytotoxic brain edema (CBE) was created by an acute reduction in blood osmolality." | 1.30 | The effects of intravenous anesthetics on intracranial pressure and cerebral perfusion pressure in two feline models of brain edema. ( Nimkoff, L; Quinn, C; Sagy, M; Silver, P, 1997) |
| "Cerebral edema was assessed 0." | 1.28 | Influence of thermal stress and various agents on the brain edema formation in rats following a cryogenic brain lesion. ( Chiu, WT; Lin, LS; Lin, MT; Shih, CJ, 1989) |
| "Focal cerebral ischemia initiates multiple detrimental effects in the brain." | 1.27 | Indomethacin-mediated improvement following middle cerebral artery occlusion in cats. Effects of anesthesia. ( Dempsey, RJ; Donaldson, DL; Meyer, KL; Roy, MW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Villelli, N | 1 |
| Hauser, N | 1 |
| Gianaris, T | 1 |
| Froberg, BA | 1 |
| Fulkerson, DH | 1 |
| Cai, SN | 1 |
| Zhu, SM | 1 |
| Ward, JL | 1 |
| Harting, MT | 1 |
| Cox, CS | 1 |
| Mercer, DW | 1 |
| Bleilevens, C | 1 |
| Roehl, AB | 1 |
| Goetzenich, A | 1 |
| Zoremba, N | 1 |
| Kipp, M | 1 |
| Dang, J | 1 |
| Tolba, R | 1 |
| Rossaint, R | 1 |
| Hein, M | 1 |
| Shapira, Y | 1 |
| Lam, AM | 1 |
| Eng, CC | 1 |
| Laohaprasit, V | 1 |
| Michel, M | 1 |
| Nimkoff, L | 1 |
| Quinn, C | 1 |
| Silver, P | 1 |
| Sagy, M | 1 |
| Mills, CD | 1 |
| Robertson, CS | 1 |
| Contant, CF | 1 |
| Henley, CM | 1 |
| Siegal, T | 2 |
| Shohami, E | 1 |
| Lossos, F | 1 |
| Gaab, MR | 1 |
| Poch, B | 1 |
| Heller, V | 1 |
| Lin, LS | 1 |
| Chiu, WT | 1 |
| Shih, CJ | 1 |
| Lin, MT | 1 |
| Dempsey, RJ | 1 |
| Roy, MW | 1 |
| Meyer, KL | 1 |
| Donaldson, DL | 1 |
| Pichlmayr, I | 1 |
| Brophy, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketamine and Brain Swelling
| Article | Year |
|---|---|
[Basis and new aspects of the effect of anaesthetics on cerebral function].
Topics: Anesthetics; Barbiturates; Brain; Brain Edema; Brain Neoplasms; Cerebrovascular Circulation; Chlorof | 1973 |
1 trial available for ketamine and Brain Swelling
| Article | Year |
|---|---|
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction; | 2013 |
11 other studies available for ketamine and Brain Swelling
| Article | Year |
|---|---|
Severe bilateral cerebellar edema from ingestion of ketamine: case report.
Topics: Analgesics; Brain Edema; Cerebellum; Female; Humans; Infant; Ketamine; Magnetic Resonance Imaging | 2017 |
[The effects of ketamine pretreated on cerebral edema and AQP4 expression after transient focal cerebral ischemia/reperfusion in rats].
Topics: Animals; Aquaporin 4; Brain; Brain Edema; Brain Ischemia; Ischemic Preconditioning; Ketamine; Male; | 2010 |
Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Injuries; Cytokines; Endotoxemia; Endotoxins; Keta | 2011 |
Therapeutic time window and dose response of the beneficial effects of ketamine in experimental head injury.
Topics: Analysis of Variance; Animals; Brain; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Dose-Respons | 1994 |
The effects of intravenous anesthetics on intracranial pressure and cerebral perfusion pressure in two feline models of brain edema.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Blood Pressure; Brain Edema; Cats; Cerebrov | 1997 |
Effects of anesthesia on polyamine metabolism and water content in the rat brain.
Topics: Anesthesia, General; Anesthetics, General; Animals; Biogenic Polyamines; Body Water; Brain Chemistry | 1997 |
Experimental neoplastic spinal cord compression: effect of ketamine and MK-801 on edema and prostaglandins.
Topics: Analysis of Variance; Animals; Brain Edema; Dibenzocycloheptenes; Dizocilpine Maleate; Edema; Histio | 1990 |
Oxygen tension, oxygen metabolism, and microcirculation in vasogenic brain edema.
Topics: Animals; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Cold Temperature; Ketamine; Male; | 1990 |
Influence of thermal stress and various agents on the brain edema formation in rats following a cryogenic brain lesion.
Topics: Animals; Body Water; Brain Edema; Brain Injuries; Cold Temperature; Glycerol; Hot Temperature; Ketam | 1989 |
Indomethacin-mediated improvement following middle cerebral artery occlusion in cats. Effects of anesthesia.
Topics: Animals; Brain Edema; Brain Ischemia; Cats; Cerebral Arteries; Cerebrovascular Circulation; Evoked P | 1985 |
Paediatric neurosurgical and neuroradiological anaesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics; Blood-Brain Barrier; Brain Edema; Carbon D | 1973 |