Page last updated: 2024-10-29

ketamine and Brain Inflammation

ketamine has been researched along with Brain Inflammation in 7 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
" Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)."5.17Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013)
" Surprisingly, the effects of ketamine in the context of stressor exposure, as well as the consequences of its chronic use are unclear."1.46Ketamine modulates hippocampal neurogenesis and pro-inflammatory cytokines but not stressor induced neurochemical changes. ( Anisman, H; Clarke, M; Dwyer, Z; Hayley, S; Litteljohn, D; Pentz, R; Prowse, N; Razmjou, S, 2017)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Ioku, T1
Inoue, T1
Kuki, I1
Imai, K1
Yamamoto, A1
Cho, M1
Ibrahim, WW1
Sayed, RH1
Kandil, EA1
Wadie, W1
Réus, GZ2
Simões, LR1
Colpo, GD1
Scaini, G1
Oses, JP1
Generoso, JS1
Prossin, AR1
Kaddurah-Daouk, R1
Quevedo, J2
Barichello, T1
Caputo, D1
Iorio, R1
Vigevano, F1
Fusco, L1
Clarke, M1
Razmjou, S1
Prowse, N1
Dwyer, Z1
Litteljohn, D1
Pentz, R1
Anisman, H1
Hayley, S1
Abelaira, HM1
Ignácio, ZM1
Dos Santos, MAB1
de Moura, AB1
Matos, D1
Demo, JP1
da Silva, JBI1
Danielski, LG1
Petronilho, F1
Carvalho, AF1
Bleilevens, C1
Roehl, AB1
Goetzenich, A1
Zoremba, N1
Kipp, M1
Dang, J1
Tolba, R1
Rossaint, R1
Hein, M1

Trials

1 trial available for ketamine and Brain Inflammation

ArticleYear
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
    Experimental brain research, 2013, Volume: 224, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction;

2013

Other Studies

6 other studies available for ketamine and Brain Inflammation

ArticleYear
[A case of febrile infection-related epilepsy syndrome requiring prolonged intensive care management: a trial of intravenous ketamine and intrathecal dexamethasone therapy].
    Rinsho shinkeigaku = Clinical neurology, 2022, Feb-19, Volume: 62, Issue:2

    Topics: Adolescent; Critical Care; Dexamethasone; Drug Resistant Epilepsy; Encephalitis; Epileptic Syndromes

2022
Niacin mitigates blood-brain barrier tight junctional proteins dysregulation and cerebral inflammation in ketamine rat model of psychosis: Role of GPR109A receptor.
    Progress in neuro-psychopharmacology & biological psychiatry, 2022, 12-20, Volume: 119

    Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Encephalitis; Hypolipidemic Agents; Ketamine;

2022
Ketamine potentiates oxidative stress and influences behavior and inflammation in response to lipolysaccharide (LPS) exposure in early life.
    Neuroscience, 2017, 06-14, Volume: 353

    Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Corpus Striatum; Cytokines; Disease Models, Anim

2017
Febrile infection-related epilepsy syndrome (FIRES) with super-refractory status epilepticus revealing autoimmune encephalitis due to GABA
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2018, Volume: 22, Issue:1

    Topics: Adolescent; Anticonvulsants; Autoantibodies; Drug Resistant Epilepsy; Encephalitis; Epileptic Syndro

2018
Ketamine modulates hippocampal neurogenesis and pro-inflammatory cytokines but not stressor induced neurochemical changes.
    Neuropharmacology, 2017, Volume: 112, Issue:Pt A

    Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Corticosterone; Cytokines; Encephalitis; Hippoc

2017
Ketamine Exhibits Different Neuroanatomical Profile After Mammalian Target of Rapamycin Inhibition in the Prefrontal Cortex: the Role of Inflammation and Oxidative Stress.
    Molecular neurobiology, 2017, Volume: 54, Issue:7

    Topics: Amygdala; Animals; Antidepressive Agents; Antioxidants; Encephalitis; Ketamine; Male; Oxidative Stre

2017