ketamine has been researched along with Brain Disorders in 19 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketamine is said to increase intracranial pressure (ICP), cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) and hence to be unsuitable for neuroanaesthesia." | 2.39 | [Cerebral neuroprotection and ketamine]. ( Jantzen, JP, 1994) |
| "Influenza-associated encephalopathy (IAE) is characterized by severe neurological complications during high-grade fever with high morbidity and mortality in children." | 1.36 | Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo. ( Cissé, Y; Inoue, I; Kido, H; Wang, S, 2010) |
| "Treatment with ketamine, a non-competitive glutamate N-methyl-d-aspartic acid (NMDA) receptor antagonist, is known to have paradoxical effects of neuroprotection and neurotoxicity." | 1.34 | The expression of Troponin T1 gene is induced by ketamine in adult mouse brain. ( Lowe, XR; Lu, X; Marchetti, F; Wyrobek, AJ, 2007) |
| "Ketamine and N(2)O were administered alone or in combination by various dosing regimens to adult female rats for a duration of 3 h and the severity of cerebrocortical neurotoxic changes was quantified histologically." | 1.31 | Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats. ( Benshoff, N; Jevtovic-Todorovic, V; Olney, JW, 2000) |
| "In flurothyl-treated rats, there were significant reductions in SNPR neuropathologic grade (P = 0." | 1.29 | Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats. ( Garman, RH; Graybeal, JM; Hawkins, RA; Housman, C; Kofke, WA; Towfighi, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, C | 1 |
| Liu, F | 1 |
| Patterson, TA | 1 |
| Paule, MG | 1 |
| Slikker, W | 1 |
| Zeiler, FA | 1 |
| Teitelbaum, J | 1 |
| West, M | 1 |
| Gillman, LM | 1 |
| Zhao, CH | 1 |
| Li, GH | 1 |
| Wang, Q | 1 |
| Zhao, B | 1 |
| Wang, ZB | 1 |
| Valentine, BA | 1 |
| Riebold, TW | 1 |
| Wolff, PL | 1 |
| Sanchez, AL | 1 |
| Cissé, Y | 1 |
| Wang, S | 1 |
| Inoue, I | 1 |
| Kido, H | 1 |
| Lowe, XR | 1 |
| Lu, X | 1 |
| Marchetti, F | 1 |
| Wyrobek, AJ | 1 |
| Burrows, FA | 1 |
| Seeman, RG | 1 |
| Jantzen, JP | 1 |
| Kofke, WA | 1 |
| Towfighi, J | 1 |
| Garman, RH | 1 |
| Graybeal, JM | 1 |
| Housman, C | 1 |
| Hawkins, RA | 1 |
| Jevtovic-Todorovic, V | 1 |
| Benshoff, N | 1 |
| Olney, JW | 1 |
| Kmiolek, W | 1 |
| Hausler, R | 1 |
| Cao, M | 1 |
| Magnin, C | 1 |
| Mulette, P | 1 |
| McDonald, JW | 1 |
| Roeser, NF | 1 |
| Silverstein, FS | 1 |
| Johnston, MV | 1 |
| Hunter, AR | 1 |
| Marcy, JH | 1 |
| Hiles, DA | 1 |
| Shaprio, HM | 1 |
| Wyte, SR | 1 |
| Harris, AB | 1 |
| Gibbs, JM | 1 |
| Janis, KM | 1 |
| Wright, W | 1 |
| Trãvnĩcek, V | 1 |
| Vladyka, V | 1 |
| Stejskal, L | 1 |
| Skrŭzny, J | 1 |
5 reviews available for ketamine and Brain Disorders
| Article | Year |
|---|---|
Preclinical assessment of ketamine.
Topics: Animals; Brain Diseases; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Ketamine; Neu | 2013 |
The ketamine effect on intracranial pressure in nontraumatic neurological illness.
Topics: Adult; Anesthetics, Dissociative; Brain Diseases; Child; Humans; Intracranial Pressure; Ketamine; Ma | 2014 |
[Cerebral neuroprotection and ketamine].
Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Humans; Hypoxia, Brain; Ketamine; Time Fact | 1994 |
Drugs for producing dissociative states.
Topics: Anesthesia, Dental; Anesthetics; Anesthetics, Dissociative; Brain Diseases; Cardiac Catheterization; | 1973 |
Anesthesia for pediatric ophthalmic operations.
Topics: Adolescent; Ambulatory Care; Anesthesiology; Atropine; Barbiturates; Brain Diseases; Child; Child, P | 1973 |
14 other studies available for ketamine and Brain Disorders
| Article | Year |
|---|---|
Mechanisms of propofol attenuation of ketamine-induced neonatal brain injury.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Brain Diseases; Cognition Disorders; Disease Models, A | 2016 |
Cerebral injury from intracarotid injection in an alpaca (Vicugna pacos).
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; | 2009 |
Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo.
Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Brain; Brain Diseases; Cerebral Corte | 2010 |
The expression of Troponin T1 gene is induced by ketamine in adult mouse brain.
Topics: Age Factors; Animals; Behavior, Animal; Brain; Brain Diseases; Disease Models, Animal; Excitatory Am | 2007 |
Ketamine and myoclonic encephalopathy of infants (Kinsbourne syndrome).
Topics: Anesthesia; Brain Diseases; Humans; Infant; Infant, Newborn; Ketamine; Male; Myoclonus; Syndrome; Th | 1982 |
Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats.
Topics: 3-Mercaptopropionic Acid; Administration, Inhalation; Anesthetics; Animals; Brain Diseases; Flurothy | 1993 |
Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats.
Topics: Anesthetics, Dissociative; Animals; Brain Diseases; Cerebral Cortex; Drug Synergism; Female; GABA Ag | 2000 |
[Reactions and complications following pneumoencephalography in children with central nervous system diseases depending on the type of pharmacological premedication and some clinical indices].
Topics: Adolescent; Age Factors; Brain Diseases; Child; Child, Preschool; Chloral Hydrate; Halothane; Humans | 1976 |
Low frequency hearing threshold determination in newborns, infants and mentally retarded children by middle latency responses.
Topics: Acoustic Stimulation; Audiometry, Evoked Response; Audiometry, Pure-Tone; Auditory Threshold; Brain | 1991 |
Quantitative assessment of neuroprotection against NMDA-induced brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dibenzo | 1989 |
Ketamine anaesthesia in patients with intracranial pathology.
Topics: Anesthesia, Intravenous; Blood Pressure; Brain Diseases; Child; Humans; Injections, Intravenous; Int | 1972 |
The effect of intravenous ketamine on cerebrospinal fluid pressure.
Topics: Anesthesia; Blood Pressure; Brain Diseases; Cerebrospinal Fluid; Humans; Injections, Intravenous; In | 1972 |
Failure to produce analgesia with ketamine in two patients with cortical disease.
Topics: Analgesia; Anesthetics; Brain; Brain Diseases; Cyclohexanes; Humans; Infant, Newborn; Infant, Newbor | 1972 |
[Ketalar in neurosurgical patients].
Topics: Adolescent; Adult; Anesthetics; Brain Diseases; Central Nervous System; Cyclohexanes; Electroencepha | 1972 |