ketamine has been researched along with Blood Poisoning in 31 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etomidate is used less frequently in sepsis patients than nonsepsis patients, with ketamine being the most frequently used alternative." | 7.96 | Etomidate Use Is Associated With Less Hypotension Than Ketamine for Emergency Department Sepsis Intubations: A NEAR Cohort Study. ( Brown, CA; Kaji, AH; Mohr, NM; Pape, SG; Runde, D; Walls, RM, 2020) |
| "Ketamine was associated with a lower incidence of clinical hypotension within the 24 hour period following endotracheal intubation in septic patients." | 7.85 | Increased incidence of clinical hypotension with etomidate compared to ketamine for intubation in septic patients: A propensity matched analysis. ( Ali, NA; Cape, KM; Doepker, BA; Exline, MC; Phillips, G; Ryder, LP; Van Berkel, MA, 2017) |
| "This study aimed to evaluate the effect of sepsis on behavioral changes on the ketamine-induced animal model of schizophrenia." | 7.81 | Effect of sepsis on behavioral changes on the ketamine-induced animal model of schizophrenia. ( Barichello, T; Bittencourt, MO; Cassol, OJ; Comim, CM; Dal-Pizzol, F; Mendonça, BP; Palmas, D; Patrício, JJ; Quevedo, J; Silva, NC; Zugno, AI, 2015) |
| "C57BL/6 mice received ketamine or sevoflurane anesthesia during laparotomy, which was followed by an E." | 7.76 | The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010) |
| "Ketamine improved 12h survival and delayed mortality after hemorrhage+sepsis without significantly altering IL-6, and did not alter survival or IL-6 after hemorrhage alone." | 7.75 | Ketamine delays mortality in an experimental model of hemorrhagic shock and subsequent sepsis. ( Artru, A; Czeiger, D; Douvdevani, A; Grinberg, G; Shaked, G; Shapira, Y; Sufaro, Y, 2009) |
| "This study was designed to investigate the effects of ketamine on levels of inflammatory cytokines, nuclear factor-kappa B (NF-kappaB) and Toll-like receptors (TLRs) in rat intestine during polymicrobial sepsis, induced by cecal ligation and puncture (CLP)." | 7.74 | Effects of ketamine on levels of cytokines, NF-kappaB and TLRs in rat intestine during CLP-induced sepsis. ( Liu, J; Shao, D; Xu, J; Yu, M; Zhang, Z; Zhu, J, 2007) |
| "After the induction of sepsis or sham-operation, animals were treated with ketamine (0." | 7.74 | Effects of ketamine on pulmonary inflammatory responses and survival in rats exposed to polymicrobial sepsis. ( Feng, X; Shao, D; Xu, J; Yang, R; Yu, M; Zhu, S, 2007) |
| "Ketamine was reported to decrease cytokine production and improve survival after Escherichia coli-induced sepsis." | 7.73 | Ketamine improves survival in burn injury followed by sepsis in rats. ( Artru, AA; Czeiger, D; Douvdevani, A; Gurfinkel, R; Mazar, J; Shaked, G; Shapira, Y; Sufaro, Y, 2006) |
| "To explore the effects of ketamine on hemo-dynamics, plasma proinflammatory cytokine (TNF-alpha and IL-6) levels and nuclear factor kappa B (NF-kappaB) activation during polymicrobial sepsis." | 7.73 | Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats. ( Du, ZH; Jia, BH; Ke, JJ; Li, JG; Song, XM; Wang, YL; Zhou, Q, 2006) |
| "Ketamine is an analgesic/anesthetic drug, which, in combination with other drugs, has been used as anesthetic for over 40 years." | 5.38 | Improved methods for thermal rearrangement of alicyclic α-hydroxyimines to α-aminoketones: synthesis of ketamine analogues as antisepsis candidates. ( Byk, G; Douvdevani, A; Eini, H; Elhawi, H, 2012) |
| "Sevoflurane was used as the sole anaesthetic agent." | 5.31 | Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001) |
| " In this study, we examined whether (R)-ketamine could prevent against lethal sepsis-induced systemic inflammation and inflammatory organ injury." | 4.02 | (R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture. ( Hashimoto, K; Hashimoto, Y; Ma, L; Qu, Y; Shan, J; Wan, X; Zhang, J, 2021) |
| "Etomidate is used less frequently in sepsis patients than nonsepsis patients, with ketamine being the most frequently used alternative." | 3.96 | Etomidate Use Is Associated With Less Hypotension Than Ketamine for Emergency Department Sepsis Intubations: A NEAR Cohort Study. ( Brown, CA; Kaji, AH; Mohr, NM; Pape, SG; Runde, D; Walls, RM, 2020) |
| "Ketamine was associated with a lower incidence of clinical hypotension within the 24 hour period following endotracheal intubation in septic patients." | 3.85 | Increased incidence of clinical hypotension with etomidate compared to ketamine for intubation in septic patients: A propensity matched analysis. ( Ali, NA; Cape, KM; Doepker, BA; Exline, MC; Phillips, G; Ryder, LP; Van Berkel, MA, 2017) |
| "This study aimed to evaluate the effect of sepsis on behavioral changes on the ketamine-induced animal model of schizophrenia." | 3.81 | Effect of sepsis on behavioral changes on the ketamine-induced animal model of schizophrenia. ( Barichello, T; Bittencourt, MO; Cassol, OJ; Comim, CM; Dal-Pizzol, F; Mendonça, BP; Palmas, D; Patrício, JJ; Quevedo, J; Silva, NC; Zugno, AI, 2015) |
| "C57BL/6 mice received ketamine or sevoflurane anesthesia during laparotomy, which was followed by an E." | 3.76 | The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia. ( Habu, Y; Kazama, T; Kinoshita, M; Ogura, T; Seki, S; Shono, S; Takahashi, T, 2010) |
| "Ketamine improved 12h survival and delayed mortality after hemorrhage+sepsis without significantly altering IL-6, and did not alter survival or IL-6 after hemorrhage alone." | 3.75 | Ketamine delays mortality in an experimental model of hemorrhagic shock and subsequent sepsis. ( Artru, A; Czeiger, D; Douvdevani, A; Grinberg, G; Shaked, G; Shapira, Y; Sufaro, Y, 2009) |
| "This study was designed to investigate the effects of ketamine on levels of inflammatory cytokines, nuclear factor-kappa B (NF-kappaB) and Toll-like receptors (TLRs) in rat intestine during polymicrobial sepsis, induced by cecal ligation and puncture (CLP)." | 3.74 | Effects of ketamine on levels of cytokines, NF-kappaB and TLRs in rat intestine during CLP-induced sepsis. ( Liu, J; Shao, D; Xu, J; Yu, M; Zhang, Z; Zhu, J, 2007) |
| "After the induction of sepsis or sham-operation, animals were treated with ketamine (0." | 3.74 | Effects of ketamine on pulmonary inflammatory responses and survival in rats exposed to polymicrobial sepsis. ( Feng, X; Shao, D; Xu, J; Yang, R; Yu, M; Zhu, S, 2007) |
| "Ketamine, only at a supra-anesthetic dosage, could inhibit endotoxin-induced pulmonary inflammation in vivo." | 3.73 | Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats. ( Duan, M; Li, W; Lin, N; Sun, J; Wang, Z; Xu, J; Yang, J; Zhou, Z, 2005) |
| "The current data suggest that the sepsis-protective antiinflammatory effects of ketamine are mediated by the release of adenosine acting through the A2A receptor." | 3.73 | Involvement of adenosine in the antiinflammatory action of ketamine. ( Byk, G; Chaimovitz, C; Czeiger, D; Douvdevani, A; Mazar, J; Mukmenev, I; Rogachev, B; Shaked, G; Ziv, NY; Zlotnik, M, 2005) |
| "Ketamine was reported to decrease cytokine production and improve survival after Escherichia coli-induced sepsis." | 3.73 | Ketamine improves survival in burn injury followed by sepsis in rats. ( Artru, AA; Czeiger, D; Douvdevani, A; Gurfinkel, R; Mazar, J; Shaked, G; Shapira, Y; Sufaro, Y, 2006) |
| "To explore the effects of ketamine on hemo-dynamics, plasma proinflammatory cytokine (TNF-alpha and IL-6) levels and nuclear factor kappa B (NF-kappaB) activation during polymicrobial sepsis." | 3.73 | Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats. ( Du, ZH; Jia, BH; Ke, JJ; Li, JG; Song, XM; Wang, YL; Zhou, Q, 2006) |
| "Ketamine has been shown to reduce sepsis-induced pathological complications." | 1.40 | Ketamine inhibits LPS-induced HGMB1 release in vitro and in vivo. ( Wu, H; Zhang, L; Zhang, Z; Zhou, C, 2014) |
| "Ketamine is an analgesic/anesthetic drug, which, in combination with other drugs, has been used as anesthetic for over 40 years." | 1.38 | Improved methods for thermal rearrangement of alicyclic α-hydroxyimines to α-aminoketones: synthesis of ketamine analogues as antisepsis candidates. ( Byk, G; Douvdevani, A; Eini, H; Elhawi, H, 2012) |
| " Therefore, we tested the dose-response direct cardiac effects of clinically available induction agents in an isolated septic rat heart model." | 1.35 | Cardiac effects of induction agents in the septic rat heart. ( Busse, H; Graf, BM; Lunz, D; Sinner, B; Zausig, YA; Zink, W, 2009) |
| "Ketamine has hepatoprotective effects against LPS-induced liver injury that appear to be mediated, at least in part, by differential modulation of the oxidative stress proteins iNOS and HO-1." | 1.33 | Differential effects of anesthetics on endotoxin-induced liver injury. ( Gonzalez, EA; Helmer, KS; Kennison, SD; Mercer, DW; Suliburk, JW, 2005) |
| "Sevoflurane was used as the sole anaesthetic agent." | 1.31 | Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model. ( Allaouchiche, B; Chassard, D; Debon, R; Duflo, F; Tournadre, JP, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 12 (38.71) | 24.3611 |
| 2020's | 5 (16.13) | 2.80 |
| Authors | Studies |
|---|---|
| Mohr, NM | 2 |
| Faine, B | 1 |
| Srivilaithon, W | 1 |
| Bumrungphanithaworn, A | 1 |
| Daorattanachai, K | 1 |
| Limjindaporn, C | 1 |
| Amnuaypattanapon, K | 1 |
| Imsuwan, I | 1 |
| Diskumpon, N | 1 |
| Dasanadeba, I | 1 |
| Siripakarn, Y | 1 |
| Ueamsaranworakul, T | 1 |
| Pornpanit, C | 1 |
| Pornpachara, V | 1 |
| Pape, SG | 1 |
| Runde, D | 1 |
| Kaji, AH | 1 |
| Walls, RM | 1 |
| Brown, CA | 1 |
| Wang, M | 1 |
| Cai, XF | 1 |
| Zhang, SM | 1 |
| Xia, SY | 1 |
| Du, WH | 1 |
| Ma, YL | 1 |
| Zhang, J | 1 |
| Ma, L | 1 |
| Hashimoto, Y | 1 |
| Wan, X | 1 |
| Shan, J | 1 |
| Qu, Y | 1 |
| Hashimoto, K | 1 |
| Sihra, N | 1 |
| Ockrim, J | 1 |
| Wood, D | 1 |
| Zhang, Z | 2 |
| Zhang, L | 1 |
| Zhou, C | 1 |
| Wu, H | 1 |
| Wang, F | 1 |
| Meng, Y | 1 |
| Zhang, Y | 1 |
| Zhao, G | 1 |
| Zheng, X | 1 |
| Xiao, Q | 1 |
| Yu, Y | 1 |
| Comim, CM | 1 |
| Silva, NC | 1 |
| Patrício, JJ | 1 |
| Palmas, D | 1 |
| Mendonça, BP | 1 |
| Bittencourt, MO | 1 |
| Cassol, OJ | 1 |
| Barichello, T | 1 |
| Zugno, AI | 1 |
| Quevedo, J | 1 |
| Dal-Pizzol, F | 1 |
| Li, K | 1 |
| Yang, J | 2 |
| Han, X | 1 |
| Van Berkel, MA | 1 |
| Exline, MC | 1 |
| Cape, KM | 1 |
| Ryder, LP | 1 |
| Phillips, G | 1 |
| Ali, NA | 1 |
| Doepker, BA | 1 |
| Burmon, C | 1 |
| Adamakos, F | 1 |
| Filardo, M | 1 |
| Motov, S | 1 |
| Shaked, G | 4 |
| Grinberg, G | 1 |
| Sufaro, Y | 2 |
| Douvdevani, A | 5 |
| Shapira, Y | 3 |
| Artru, A | 1 |
| Czeiger, D | 4 |
| Zausig, YA | 1 |
| Busse, H | 1 |
| Lunz, D | 1 |
| Sinner, B | 1 |
| Zink, W | 1 |
| Graf, BM | 1 |
| Wittebole, X | 1 |
| Castanares-Zapatero, D | 1 |
| Laterre, PF | 1 |
| Medhi, B | 1 |
| Kaur, S | 1 |
| Sarangi, SC | 1 |
| Takahashi, T | 1 |
| Kinoshita, M | 1 |
| Shono, S | 1 |
| Habu, Y | 1 |
| Ogura, T | 1 |
| Seki, S | 1 |
| Kazama, T | 1 |
| Elhawi, H | 1 |
| Eini, H | 1 |
| Byk, G | 2 |
| Tsao, CM | 1 |
| Wu, CC | 1 |
| Dukhno, O | 1 |
| Levy, I | 1 |
| Artru, AA | 2 |
| Suliburk, JW | 1 |
| Gonzalez, EA | 1 |
| Kennison, SD | 1 |
| Helmer, KS | 1 |
| Mercer, DW | 1 |
| Li, W | 1 |
| Duan, M | 1 |
| Zhou, Z | 1 |
| Lin, N | 1 |
| Wang, Z | 1 |
| Sun, J | 1 |
| Xu, J | 3 |
| Westphal, M | 2 |
| Traber, DL | 1 |
| Mazar, J | 2 |
| Rogachev, B | 1 |
| Ziv, NY | 1 |
| Chaimovitz, C | 1 |
| Zlotnik, M | 1 |
| Mukmenev, I | 1 |
| Lange, M | 1 |
| Bröking, K | 1 |
| van Aken, H | 1 |
| Hucklenbruch, C | 1 |
| Bone, HG | 1 |
| Gurfinkel, R | 1 |
| Song, XM | 1 |
| Li, JG | 1 |
| Wang, YL | 1 |
| Zhou, Q | 1 |
| Du, ZH | 1 |
| Jia, BH | 1 |
| Ke, JJ | 1 |
| Yu, M | 2 |
| Shao, D | 2 |
| Liu, J | 1 |
| Zhu, J | 1 |
| Yang, R | 1 |
| Feng, X | 1 |
| Zhu, S | 1 |
| Allaouchiche, B | 1 |
| Duflo, F | 1 |
| Tournadre, JP | 1 |
| Debon, R | 1 |
| Chassard, D | 1 |
| Levin, JM | 1 |
| Bornstein, LA | 1 |
2 reviews available for ketamine and Blood Poisoning
| Article | Year |
|---|---|
Toll-like receptor 4 modulation as a strategy to treat sepsis.
Topics: Analgesics; Analgesics, Opioid; Animals; Antibodies; Antirheumatic Agents; Chloroquine; Cholecalcife | 2010 |
[Role of ketamine in sepsis and systemic inflammatory response syndrome].
Topics: Adenosine Triphosphate; Anesthetics, Dissociative; Anti-Inflammatory Agents, Non-Steroidal; Blood Pr | 2006 |
1 trial available for ketamine and Blood Poisoning
| Article | Year |
|---|---|
Clinical outcomes after a single induction dose of etomidate versus ketamine for emergency department sepsis intubation: a randomized controlled trial.
Topics: Adolescent; Adult; Anesthetics, Intravenous; Emergency Service, Hospital; Etomidate; Humans; Intubat | 2023 |
28 other studies available for ketamine and Blood Poisoning
| Article | Year |
|---|---|
Etomidate for endotracheal intubation in sepsis.
Topics: Anesthetics, Intravenous; Etomidate; Humans; Intubation, Intratracheal; Ketamine; Sepsis | 2023 |
Etomidate Use Is Associated With Less Hypotension Than Ketamine for Emergency Department Sepsis Intubations: A NEAR Cohort Study.
Topics: Cohort Studies; Emergency Service, Hospital; Etomidate; Humans; Hypotension; Intubation, Intratrache | 2020 |
Alprostadil alleviates liver injury in septic rats via TLR4/NF-κB pathway.
Topics: Alprostadil; Animals; Ketamine; Liver; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Sepsi | 2021 |
(R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture.
Topics: Animals; Biomarkers; Cecum; Cytokines; Disease Models, Animal; Inflammation; Inflammation Mediators; | 2021 |
The effects of recreational ketamine cystitis on urinary tract reconstruction - a surgical challenge.
Topics: Acute Kidney Injury; Adult; Anastomotic Leak; Anesthetics, Dissociative; Cystitis; Female; Humans; I | 2018 |
Ketamine inhibits LPS-induced HGMB1 release in vitro and in vivo.
Topics: Animals; Cecum; Cell Line; Disease Models, Animal; HMGB1 Protein; Humans; Imidazoles; Ketamine; Lipo | 2014 |
RETRACTED: Ketamine reduces lipopolysaccharide-induced high-mobility group box-1 through heme oxygenase-1 and nuclear factor erythroid 2-related factor 2/ p38 mitogen-activated protein kinase.
Topics: Acute Lung Injury; Anesthetics, Dissociative; Animals; Cell Line; Cell Survival; Disease Models, Ani | 2015 |
Effect of sepsis on behavioral changes on the ketamine-induced animal model of schizophrenia.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Interpersonal Relations; Ketamine | 2015 |
Ketamine attenuates sepsis-induced acute lung injury via regulation of HMGB1-RAGE pathways.
Topics: Acute Lung Injury; Animals; Animals, Genetically Modified; Antibodies, Blocking; Extracellular Signa | 2016 |
Increased incidence of clinical hypotension with etomidate compared to ketamine for intubation in septic patients: A propensity matched analysis.
Topics: Anesthetics, Intravenous; Cohort Studies; Critical Care; Critical Illness; Etomidate; Female; Humans | 2017 |
Acute pulmonary edema associated with ketamine-induced hypertension during procedural sedation in the ED.
Topics: Acute Disease; Anesthetics, Dissociative; Anti-Bacterial Agents; Arthralgia; Arthrocentesis; Cardiop | 2017 |
Ketamine delays mortality in an experimental model of hemorrhagic shock and subsequent sepsis.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Exc | 2009 |
Cardiac effects of induction agents in the septic rat heart.
Topics: Analgesics; Anesthetics, Intravenous; Animals; Cardiomyopathies; Dose-Response Relationship, Drug; G | 2009 |
Effect of low dose of ketamine in sepsis with gastrointestinal complication.
Topics: Anesthetics, Dissociative; Animals; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Ketam | 2010 |
The effect of ketamine anesthesia on the immune function of mice with postoperative septicemia.
Topics: Anesthesia; Animals; Cytokines; Escherichia coli; Escherichia coli Infections; Ketamine; Laparotomy; | 2010 |
Improved methods for thermal rearrangement of alicyclic α-hydroxyimines to α-aminoketones: synthesis of ketamine analogues as antisepsis candidates.
Topics: Animals; Anti-Infective Agents, Local; Disease Models, Animal; Female; Imines; Interleukin-6; Ketami | 2012 |
Modulating effects of ketamine on inflammatory response in sepsis.
Topics: Apoptosis; Humans; Inflammation; Ketamine; Sepsis | 2012 |
Ketamine improves survival and suppresses IL-6 and TNFalpha production in a model of Gram-negative bacterial sepsis in rats.
Topics: Anesthetics, Dissociative; Animals; Escherichia coli Infections; Interleukin-6; Ketamine; Male; Rats | 2004 |
Differential effects of anesthetics on endotoxin-induced liver injury.
Topics: Anesthetics; Animals; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Isoflurane; Ketamine; | 2005 |
Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats.
Topics: Animals; Cell Nucleus; Disease Progression; Dose-Response Relationship, Drug; Edema; Endotoxins; Enz | 2005 |
Ketamine in critical illness: another no-NO agent?
Topics: Analgesics; Apoptosis; Blood Pressure; Humans; Ketamine; Microcirculation; Muscle, Smooth, Vascular; | 2005 |
Involvement of adenosine in the antiinflammatory action of ketamine.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Femal | 2005 |
Ketamine improves survival in burn injury followed by sepsis in rats.
Topics: Animals; Burns; Dose-Response Relationship, Drug; Interleukin-6; Ketamine; Male; Rats; Rats, Sprague | 2006 |
Effects of ketamine on proinflammatory cytokines and nuclear factor kappaB in polymicrobial sepsis rats.
Topics: Animals; Bacterial Infections; Cecum; Cytokines; Heart Rate; Hemodynamics; Hypotension; Inflammation | 2006 |
Effects of ketamine on levels of cytokines, NF-kappaB and TLRs in rat intestine during CLP-induced sepsis.
Topics: Animals; Cecum; Cytokines; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; E | 2007 |
Effects of ketamine on pulmonary inflammatory responses and survival in rats exposed to polymicrobial sepsis.
Topics: Animals; Cytokines; Ketamine; Male; Pneumonia; Rats; Rats, Sprague-Dawley; Sepsis; Survival Rate | 2007 |
Influence of sepsis on sevoflurane minimum alveolar concentration in a porcine model.
Topics: Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Ketamine; Methyl Ethers; Mod | 2001 |
The treatment of burns in the recent Middle East conflict.
Topics: Acute Kidney Injury; Adolescent; Adult; Anesthesia, Inhalation; Animals; Burns; Debridement; Facial | 1974 |