Page last updated: 2024-10-29

ketamine and Attention Deficit Disorder with Hyperactivity

ketamine has been researched along with Attention Deficit Disorder with Hyperactivity in 5 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)

Research Excerpts

ExcerptRelevanceReference
" The authors set out to investigate the neurotoxicity of S-ketamine, which possesses anesthetic and antidepressant effects and may cause attention deficit hyperactivity disorder (ADHD)- and depression-like behaviors in offspring mice."8.12S-ketamine administration in pregnant mice induces ADHD- and depression-like behaviors in offspring mice. ( Bai, Y; Bi, XY; Cao, L; Liu, NN; Xin, Y; Xing, BH; Zhang, DX; Zhang, LM; Zhang, W; Zheng, WC, 2022)
" The authors set out to investigate the neurotoxicity of S-ketamine, which possesses anesthetic and antidepressant effects and may cause attention deficit hyperactivity disorder (ADHD)- and depression-like behaviors in offspring mice."4.12S-ketamine administration in pregnant mice induces ADHD- and depression-like behaviors in offspring mice. ( Bai, Y; Bi, XY; Cao, L; Liu, NN; Xin, Y; Xing, BH; Zhang, DX; Zhang, LM; Zhang, W; Zheng, WC, 2022)
"We report difficulty with conscious sedation of a child taking methylphenidate for attention deficit disorder and possible delayed adverse interaction of ketamine and methylphenidate resulting in severe nausea, vomiting and dehydration."3.69Unexpected interaction of methylphenidate (Ritalin) with anaesthetic agents. ( Fox, L; Ririe, DG; Ririe, KL; Sethna, NF, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zhang, LM1
Liu, NN1
Cao, L1
Xin, Y1
Zhang, DX1
Bai, Y1
Zheng, WC1
Bi, XY1
Xing, BH1
Zhang, W1
Phillips, AG1
Geyer, MA1
Robbins, TW1
Nakako, T1
Murai, T1
Ikejiri, M1
Hashimoto, T1
Kotani, M1
Matsumoto, K1
Manabe, S1
Ogi, Y1
Konoike, N1
Nakamura, K1
Ikeda, K1
Fredriksson, A1
Archer, T1
Ririe, DG1
Ririe, KL1
Sethna, NF1
Fox, L1

Reviews

1 review available for ketamine and Attention Deficit Disorder with Hyperactivity

ArticleYear
Effective Use of Animal Models for Therapeutic Development in Psychiatric and Substance Use Disorders.
    Biological psychiatry, 2018, 06-01, Volume: 83, Issue:11

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Attention D

2018

Other Studies

4 other studies available for ketamine and Attention Deficit Disorder with Hyperactivity

ArticleYear
S-ketamine administration in pregnant mice induces ADHD- and depression-like behaviors in offspring mice.
    Behavioural brain research, 2022, 09-05, Volume: 433

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Depression; Female; Humans

2022
Effects of lurasidone on ketamine-induced joint visual attention dysfunction as a possible disease model of autism spectrum disorders in common marmosets.
    Behavioural brain research, 2014, Nov-01, Volume: 274

    Topics: Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Callithrix; Child Deve

2014
Neurobehavioural deficits associated with apoptotic neurodegeneration and vulnerability for ADHD.
    Neurotoxicity research, 2004, Volume: 6, Issue:6

    Topics: Animals; Animals, Newborn; Apoptosis; Attention Deficit Disorder with Hyperactivity; Central Nervous

2004
Unexpected interaction of methylphenidate (Ritalin) with anaesthetic agents.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:1

    Topics: Anesthetics, Dissociative; Attention Deficit Disorder with Hyperactivity; Central Nervous System Sti

1997