ketamine has been researched along with Atrophy in 6 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 44-year-old man with treated neurosyphilis presented with subclinical status epilepticus (SE) refractory to intravenous high-dose lorazepam, phenytoin, and valproic acid over 4 days." | 7.72 | Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity. ( Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA, 2003) |
| "A 44-year-old man with treated neurosyphilis presented with subclinical status epilepticus (SE) refractory to intravenous high-dose lorazepam, phenytoin, and valproic acid over 4 days." | 3.72 | Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity. ( Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA, 2003) |
| " In the present study the accuracy of long-term and short-term spatial memory for rats that had been treated with 100 mg/kg of ketamine immediately after the induction of seizures by lithium and pilocarpine did not differ from normal rats despite the conspicuous multifocal neuronal loss." | 3.71 | Normalization of spatial learning despite brain damage in rats receiving ketamine after seizure-induction: evidence for the neuromatrix. ( Persinger, MA; Vaillancourt, LN, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niciu, MJ | 1 |
| Iadarola, ND | 1 |
| Banerjee, D | 1 |
| Luckenbaugh, DA | 1 |
| Park, M | 1 |
| Lener, M | 1 |
| Park, L | 1 |
| Ionescu, DF | 1 |
| Ballard, ED | 1 |
| Brutsche, NE | 1 |
| Akula, N | 1 |
| McMahon, FJ | 1 |
| Machado-Vieira, R | 1 |
| Nugent, AC | 1 |
| Zarate, CA | 1 |
| Schobel, SA | 1 |
| Chaudhury, NH | 1 |
| Khan, UA | 1 |
| Paniagua, B | 1 |
| Styner, MA | 1 |
| Asllani, I | 1 |
| Inbar, BP | 1 |
| Corcoran, CM | 1 |
| Lieberman, JA | 1 |
| Moore, H | 1 |
| Small, SA | 1 |
| Liao, Y | 1 |
| Tang, J | 1 |
| Corlett, PR | 1 |
| Wang, X | 1 |
| Yang, M | 1 |
| Chen, H | 1 |
| Liu, T | 1 |
| Chen, X | 1 |
| Hao, W | 1 |
| Fletcher, PC | 1 |
| Ubogu, EE | 1 |
| Sagar, SM | 1 |
| Lerner, AJ | 1 |
| Maddux, BN | 1 |
| Suarez, JI | 1 |
| Werz, MA | 1 |
| Vutskits, L | 1 |
| Gascon, E | 1 |
| Potter, G | 1 |
| Tassonyi, E | 1 |
| Kiss, JZ | 1 |
| Vaillancourt, LN | 1 |
| Persinger, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Assess the Efficacy of Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy[NCT05019885] | Phase 2 | 6 participants (Anticipated) | Interventional | 2022-08-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ketamine and Atrophy
| Article | Year |
|---|---|
The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.
Topics: Adolescent; Adult; Aged; Amygdala; Antidepressive Agents; Atrophy; Brain-Derived Neurotrophic Factor | 2017 |
5 other studies available for ketamine and Atrophy
| Article | Year |
|---|---|
Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver.
Topics: Amino Acids; Animals; Atrophy; Brain Mapping; Bridged Bicyclo Compounds, Heterocyclic; Disease Model | 2013 |
Reduced dorsal prefrontal gray matter after chronic ketamine use.
Topics: Adult; Anesthetics, Dissociative; Atrophy; Brain Mapping; Female; Humans; Ketamine; Magnetic Resonan | 2011 |
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.
Topics: Adult; Anticonvulsants; Atrophy; Brain; Electroencephalography; Excitatory Amino Acid Antagonists; H | 2003 |
Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture.
Topics: Animals; Animals, Newborn; Atrophy; Cell Count; Cell Survival; Cells, Cultured; Dendrites; Dizocilpi | 2007 |
Normalization of spatial learning despite brain damage in rats receiving ketamine after seizure-induction: evidence for the neuromatrix.
Topics: Analgesics; Animals; Atrophy; Behavior, Animal; Brain; Electromagnetic Phenomena; Ketamine; Male; Ma | 2001 |