ketamine has been researched along with Asystole in 18 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the study was to investigate effects of pre-treatment with Morphine or Ketamine on hemodynamic, acid-base status, early survival, and biochemical markers of brain damage in a rat model of asphyxial cardiac arrest (ACA)." | 7.91 | The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest. ( Akhatov, N; Baigenzhin, A; Barlow, N; Dahl, V; Karibekov, T; Kondratiev, T; Konkayev, A; Konkayeva, M; Kuklin, V; Tveita, T, 2019) |
| " Of the nine patients who received ketamine, two had documented cardiac events; one remained clinically stable and the other developed multiple arrhythmias, including recurrent episodes of asystole." | 7.88 | Ketamine infusion for refractory status epilepticus: A case report of cardiac arrest. ( Farrokh, S; Geocadin, R; Koffman, L; Lewin, J; Yan Yiu, H; Ziai, W, 2018) |
| "Ketamine appears to be a safe anesthetic option for children with PAH." | 5.36 | Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010) |
| " There was no demonstrable difference in post-induction hypotension between ketamine-based and midazolam-based PHEA." | 4.12 | Cardiovascular complications of prehospital emergency anaesthesia in patients with return of spontaneous circulation following medical cardiac arrest: a retrospective comparison of ketamine-based and midazolam-based induction protocols. ( Keeliher, C; Khan-Cheema, H; King, C; Lewinsohn, A; McLachlan, S; Sherren, P; Sherrin, J, 2022) |
| " The aim of the study was to investigate effects of pre-treatment with Morphine or Ketamine on hemodynamic, acid-base status, early survival, and biochemical markers of brain damage in a rat model of asphyxial cardiac arrest (ACA)." | 3.91 | The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest. ( Akhatov, N; Baigenzhin, A; Barlow, N; Dahl, V; Karibekov, T; Kondratiev, T; Konkayev, A; Konkayeva, M; Kuklin, V; Tveita, T, 2019) |
| " Of the nine patients who received ketamine, two had documented cardiac events; one remained clinically stable and the other developed multiple arrhythmias, including recurrent episodes of asystole." | 3.88 | Ketamine infusion for refractory status epilepticus: A case report of cardiac arrest. ( Farrokh, S; Geocadin, R; Koffman, L; Lewin, J; Yan Yiu, H; Ziai, W, 2018) |
| "Cardiac arrest is a leading cause of death and disability worldwide." | 1.46 | General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish. ( Du, JL; Wang, B; Wang, YW; Xu, DJ; Zhao, X; Zheng, Y, 2017) |
| "Three patients experienced cardiac arrest without death, all associated with laryngospasm." | 1.43 | Procedural Sedation Outside of the Operating Room Using Ketamine in 22,645 Children: A Report From the Pediatric Sedation Research Consortium. ( Chumpitazi, CE; Grunwell, JR; Kamat, PP; McCracken, CE; Roback, MG; Scherrer, PD; Stockwell, JA; Stormorken, AG; Travers, C, 2016) |
| "Asystolic cardiac arrest for 8 minutes was induced in 73 rats with a mixture of potassium chloride and esmolol." | 1.42 | Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? ( Bendel, S; Grandgirard, D; Haenggi, M; Jakob, SM; Leib, SL; Pereira, A; Putzu, A; Schlickeiser, J; Springe, D; Takala, J, 2015) |
| "Two patients (10%) experienced a cardiac arrest, and both required unplanned admission to the authors' pediatric intensive care unit (PICU) postoperatively." | 1.37 | General anesthesia for children with severe heart failure. ( Haynes, SR; Murphy, TW; Ranger, MR; Smith, JH, 2011) |
| "Ketamine appears to be a safe anesthetic option for children with PAH." | 1.36 | Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. ( Bair, E; Bratton, SL; Feinstein, JA; Hammer, GB; Kamra, K; Kuan, CC; Maan, H; Ramamoorthy, C; Williams, GD, 2010) |
| "midazolam was 43." | 1.31 | Intravenous midazolam significantly enhances the lethal effect of thiopental but not that of ketamine in mice. ( Ben-Shlomo, I; Hadash, O; Katz, Y; Rosenbaum, A, 2001) |
| "Asphyxial cardiopulmonary arrest was induced and, after and 8 min cardiac arrest nonintervention interval, a standardized protocol of manual CPR with mechanical ventilation was performed." | 1.30 | Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. ( Ginn, A; Jasani, MS; Nadkarni, VM; Salzman, SK; Tice, LL, 1997) |
| "Unexpected cardiac arrest occurred in two horses during routine surgical anaesthesia." | 1.27 | Cardiac arrest during anaesthesia in two horses. ( Kellagher, RE; Watney, GC, 1986) |
| " A dosage of 30 to 40 mg of ketamine HCl/kg of body weight and 1." | 1.26 | Intravenously administered ketamine HCl and diazepam for anesthesia of raptors. ( Duke, GE; Redig, PT, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 8 (44.44) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| King, C | 1 |
| Lewinsohn, A | 1 |
| Keeliher, C | 1 |
| McLachlan, S | 1 |
| Sherrin, J | 1 |
| Khan-Cheema, H | 1 |
| Sherren, P | 1 |
| Ornowska, M | 1 |
| Wormsbecker, A | 1 |
| Andolfatto, G | 1 |
| Leung, TS | 1 |
| Khan, I | 1 |
| Medvedev, G | 1 |
| Kuklin, V | 1 |
| Akhatov, N | 1 |
| Kondratiev, T | 1 |
| Konkayev, A | 1 |
| Baigenzhin, A | 1 |
| Konkayeva, M | 1 |
| Karibekov, T | 1 |
| Barlow, N | 1 |
| Tveita, T | 1 |
| Dahl, V | 1 |
| Xu, DJ | 1 |
| Wang, B | 1 |
| Zhao, X | 1 |
| Zheng, Y | 1 |
| Du, JL | 1 |
| Wang, YW | 1 |
| Koffman, L | 1 |
| Yan Yiu, H | 1 |
| Farrokh, S | 1 |
| Lewin, J | 1 |
| Geocadin, R | 1 |
| Ziai, W | 1 |
| Bendel, S | 1 |
| Springe, D | 1 |
| Pereira, A | 1 |
| Grandgirard, D | 1 |
| Leib, SL | 1 |
| Putzu, A | 1 |
| Schlickeiser, J | 1 |
| Jakob, SM | 1 |
| Takala, J | 1 |
| Haenggi, M | 1 |
| Grunwell, JR | 1 |
| Travers, C | 1 |
| McCracken, CE | 1 |
| Scherrer, PD | 1 |
| Stormorken, AG | 1 |
| Chumpitazi, CE | 1 |
| Roback, MG | 1 |
| Stockwell, JA | 1 |
| Kamat, PP | 1 |
| Burmon, C | 1 |
| Adamakos, F | 1 |
| Filardo, M | 1 |
| Motov, S | 1 |
| Williams, GD | 1 |
| Maan, H | 1 |
| Ramamoorthy, C | 1 |
| Kamra, K | 1 |
| Bratton, SL | 1 |
| Bair, E | 1 |
| Kuan, CC | 1 |
| Hammer, GB | 1 |
| Feinstein, JA | 1 |
| Murphy, TW | 1 |
| Smith, JH | 1 |
| Ranger, MR | 1 |
| Haynes, SR | 1 |
| Ferrera, R | 1 |
| Michel, P | 1 |
| Reid, KH | 1 |
| Paskitti, M | 1 |
| Guo, SZ | 1 |
| Schmelzer, T | 1 |
| Iyer, V | 1 |
| Schöning, B | 1 |
| Sommer, K | 1 |
| Koch, H | 1 |
| Busund, R | 1 |
| Balteskard, L | 1 |
| Rønning, G | 1 |
| Høgåsen, K | 1 |
| Revhaug, A | 1 |
| Jasani, MS | 1 |
| Salzman, SK | 1 |
| Tice, LL | 1 |
| Ginn, A | 1 |
| Nadkarni, VM | 1 |
| Ben-Shlomo, I | 1 |
| Rosenbaum, A | 1 |
| Hadash, O | 1 |
| Katz, Y | 1 |
| Redig, PT | 1 |
| Duke, GE | 1 |
| Kellagher, RE | 1 |
| Watney, GC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Triple-blind Placebo Controlled Trial of Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival and Neurological Outcome[NCT04009759] | Phase 1 | 240 participants (Anticipated) | Interventional | 2021-10-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ketamine and Asystole
| Article | Year |
|---|---|
The use of ketamine as a neuroprotective agent following cardiac arrest: A scoping review of current literature.
Topics: Brain Injuries, Traumatic; Heart Arrest; Humans; Ketamine; Neuroprotection; Neuroprotective Agents | 2023 |
1 trial available for ketamine and Asystole
| Article | Year |
|---|---|
[Heart arrest during dextran infusion despite hapten blockade].
Topics: Aged; Anaphylaxis; Bronchial Spasm; Dextrans; Epinephrine; Heart Arrest; Humans; Infusions, Parenter | 1984 |
16 other studies available for ketamine and Asystole
| Article | Year |
|---|---|
Cardiovascular complications of prehospital emergency anaesthesia in patients with return of spontaneous circulation following medical cardiac arrest: a retrospective comparison of ketamine-based and midazolam-based induction protocols.
Topics: Aged; Anesthesia; Emergency Medical Services; Heart Arrest; Humans; Hypotension; Ketamine; Midazolam | 2022 |
The influences of morphine or ketamine pre-treatment on hemodynamic, acid-base status, biochemical markers of brain damage and early survival in rats after asphyxial cardiac arrest.
Topics: Analgesics, Opioid; Animals; Asphyxia; Blood Gas Analysis; Brain Injuries; Cardiopulmonary Resuscita | 2019 |
General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish.
Topics: Anesthetics, General; Animals; Apoptosis; Brain; Brain Injuries; Calcium Signaling; Heart Arrest; Ke | 2017 |
Ketamine infusion for refractory status epilepticus: A case report of cardiac arrest.
Topics: Aged; Anticonvulsants; Female; Heart Arrest; Humans; Ketamine; Status Epilepticus | 2018 |
Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model?
Topics: Anesthetics; Animals; Apoptosis; Fentanyl; Heart Arrest; Hippocampus; Ketamine; Male; Medetomidine; | 2015 |
Procedural Sedation Outside of the Operating Room Using Ketamine in 22,645 Children: A Report From the Pediatric Sedation Research Consortium.
Topics: Adolescent; Child; Child, Preschool; Emergency Service, Hospital; Female; Heart Arrest; Hospitals, G | 2016 |
Acute pulmonary edema associated with ketamine-induced hypertension during procedural sedation in the ED.
Topics: Acute Disease; Anesthetics, Dissociative; Anti-Bacterial Agents; Arthralgia; Arthrocentesis; Cardiop | 2017 |
Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine.
Topics: Adolescent; Anesthesia, General; Anesthetics, Dissociative; Blood Pressure; Cardiac Surgical Procedu | 2010 |
General anesthesia for children with severe heart failure.
Topics: Adolescent; Anesthesia, General; Anesthetics, Dissociative; Child; Child, Preschool; Female; Health | 2011 |
Protection of the ischemic heart during reperfusion: role of the low flow to avoid calcium overload into the myocardium in a pig model.
Topics: Animals; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Heart Arrest; Ketamine; | 2002 |
Experience with ketamine and sodium pentobarbital as anesthetics in a rat model of cardiac arrest and resuscitation.
Topics: Anesthetics, Dissociative; Animals; Brain; Cardiopulmonary Resuscitation; Disease Models, Animal; He | 2003 |
Fatal myocardial depression and circulatory collapse associated with complement activation induced by plasma infusion in severe porcine sepsis.
Topics: Albumins; Anesthesia, Inhalation; Animals; Blood Pressure; Blood Transfusion; Calcium; Cardiac Outpu | 1995 |
Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Combined; Anesthetics, Dissociative; Anesth | 1997 |
Intravenous midazolam significantly enhances the lethal effect of thiopental but not that of ketamine in mice.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug | 2001 |
Intravenously administered ketamine HCl and diazepam for anesthesia of raptors.
Topics: Anesthesia, General; Animals; Bird Diseases; Birds; Diazepam; Heart Arrest; Injections, Intravenous; | 1976 |
Cardiac arrest during anaesthesia in two horses.
Topics: Anesthesia; Animals; Electrocardiography; Heart Arrest; Heart Block; Heart Rate; Horse Diseases; Hor | 1986 |