ketamine has been researched along with Asthma in 47 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We determine whether a continuous infusion of ketamine can decrease the severity of a moderately severe acute asthma exacerbation by a clinically significant 2 points using a 15-point Pulmonary Index scoring scale." | 9.11 | The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma. ( Allen, JY; Macias, CG, 2005) |
| "IV ketamine at a dose low enough to avoid dysphoric reactions demonstrated no increased bronchodilatory effect compared with standard therapy in treating exacerbations of asthma in the ED." | 9.08 | Randomized, double-blind, placebo-controlled trial of intravenous ketamine in acute asthma. ( Duffy, S; Howton, JC; Levitt, MA; Rose, J; Zoltanski, T, 1996) |
| "The single study on non-intubated children with severe acute asthma did not show significant benefit and does not support the case studies and observational reports showing benefits of ketamine in both non-ventilated and ventilated children." | 8.88 | Ketamine for management of acute exacerbations of asthma in children. ( Chawla, D; Jat, KR, 2012) |
| "To evaluate the role of ketamine in management of severe exacerbation of asthma in adults." | 8.81 | Does ketamine have a role in managing severe exacerbation of asthma in adults? ( Lau, TT; Zed, PJ, 2001) |
| "We present the case of a young female with a history of allergies to medicines, specifically to benzodiazepines, who presented bronchospasm and oxygen saturation drop after receiving a dose of midazolam into her eye while she was working." | 8.12 | [Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report]. ( Ávila-García, JE; Calleja-Alarcón, S; Guerrero-Escobar, JC; Romero-Gutiérrez, L; Sánchez-Hurtado, LA, 2022) |
| "The study concluded that ketamine reduced oxidative stress and attenuated asthmatic symptoms (neutrophilic airway inflammation) by activating the Nrf2-Keap1 pathway, with 75 mg/kg ketamine showing the best results." | 8.12 | Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model. ( Wang, Q; Xiao, S; Yang, D; Zhou, Y, 2022) |
| "In this study, ketamine use was not associated with improvement in ventilatory variables associated with bronchospasm." | 7.96 | Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020) |
| "This case suggests that intravenous ketamine given in a dissociative dose may be an effective temporizing measure to avoid mechanical ventilation in adult patients with severe asthma exacerbations." | 7.77 | Intravenous ketamine in a dissociating dose as a temporizing measure to avoid mechanical ventilation in adult patient with severe asthma exacerbation. ( Hawthorne, T; Shlamovitz, GZ, 2011) |
| "A 75-year-old male diagnosed to be a case of intractable asthma resistant to all conventional therapies requiring ventilatory support, was successfully weaned off the ventilator after treatment with subanaesthetic dose of intravenous ketamine." | 7.77 | Subanaesthetic dose of ketamine in intractable asthma. ( Garg, D; Kaistha, S; Sood, D, 2011) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 7.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| "Both inhalation and systemic administration of ketamine attenuate inflammatory the lung injury and airway hyperreactivity of the OVA-induced asthma model." | 7.74 | [Protective effects of ketamine on allergen-induced airway inflammatory injure and high airway reactivity in asthma: experiment with rats]. ( Ding, ZN; Fu, CZ; Qian, YN; Rong, HB; Xu, YM; Zhu, MM; Zhu, W, 2007) |
| " Anesthesia was induced with propofol and ketamine under the Sellick maneuver." | 7.70 | [Bronchospasm during crush induction with propofol under the Sellick maneuver in a patient for emergency laparotomy]. ( Doi, K; Saito, Y; Sato, K; Yamada, Y; Yamamori, Y, 1999) |
| "Two patients with acute severe asthma, who failed to respond to conventional therapy, were given intravenous ketamine in sub-anaesthetic doses with good results." | 7.68 | Use of ketamine in acute severe asthma. ( Sarma, VJ, 1992) |
| "In vitro preparations of trachea isolated from normal and asthmatic guinea pigs were used to measure their maximum contractile response to histamine challenge and to determine spontaneous relaxation of smooth muscle of the airway." | 7.66 | Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs. ( Aldrete, JA; Cabanas, A; Souhrada, JF, 1980) |
| " We found a large heterogeneity regarding sample size, age and gender distribution, inclusion criteria (different severity scores, if any) and ketamine dosing (bolus and/or continuous infusion)." | 6.82 | Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies. ( Astuto, M; Brancati, S; Crimi, C; Cuttone, G; Dezio, V; Falcone, M; La Via, L; Sanfilippo, F, 2022) |
| "Ketamine was introduced into clinical anaesthesia in 1965." | 6.38 | [Ketamine as a broncholytic agent in status asthmaticus and as an anesthetic for patients with bronchial asthma]. ( Jørgensen, BG, 1992) |
| "Ketamine appears to increase catecholamine levels and directly relax bronchial smooth muscle." | 5.27 | Use of ketamine in asthmatic children to treat respiratory failure refractory to conventional therapy. ( L'Hommedieu, CS; Reyes de la Rocha, S; Rock, MJ; Truemper, E, 1986) |
| "Ketamine is a useful drug in the intensive treatment of status asthmaticus and should be tried before a decision is taken to start mechanical ventilation." | 5.27 | Ketamine by continuous infusion in status asthmaticus. ( Hallam, PL; Strube, PJ, 1986) |
| "Ketamine was given IV with a rapid fall in pCO2." | 5.27 | The use of ketamine for the emergency intubation of patients with status asthmaticus. ( Arens, JJ; L'Hommedieu, CS, 1987) |
| "We determine whether a continuous infusion of ketamine can decrease the severity of a moderately severe acute asthma exacerbation by a clinically significant 2 points using a 15-point Pulmonary Index scoring scale." | 5.11 | The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma. ( Allen, JY; Macias, CG, 2005) |
| "IV ketamine at a dose low enough to avoid dysphoric reactions demonstrated no increased bronchodilatory effect compared with standard therapy in treating exacerbations of asthma in the ED." | 5.08 | Randomized, double-blind, placebo-controlled trial of intravenous ketamine in acute asthma. ( Duffy, S; Howton, JC; Levitt, MA; Rose, J; Zoltanski, T, 1996) |
| "The single study on non-intubated children with severe acute asthma did not show significant benefit and does not support the case studies and observational reports showing benefits of ketamine in both non-ventilated and ventilated children." | 4.88 | Ketamine for management of acute exacerbations of asthma in children. ( Chawla, D; Jat, KR, 2012) |
| "To evaluate the role of ketamine in management of severe exacerbation of asthma in adults." | 4.81 | Does ketamine have a role in managing severe exacerbation of asthma in adults? ( Lau, TT; Zed, PJ, 2001) |
| "The study concluded that ketamine reduced oxidative stress and attenuated asthmatic symptoms (neutrophilic airway inflammation) by activating the Nrf2-Keap1 pathway, with 75 mg/kg ketamine showing the best results." | 4.12 | Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model. ( Wang, Q; Xiao, S; Yang, D; Zhou, Y, 2022) |
| "We present the case of a young female with a history of allergies to medicines, specifically to benzodiazepines, who presented bronchospasm and oxygen saturation drop after receiving a dose of midazolam into her eye while she was working." | 4.12 | [Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report]. ( Ávila-García, JE; Calleja-Alarcón, S; Guerrero-Escobar, JC; Romero-Gutiérrez, L; Sánchez-Hurtado, LA, 2022) |
| "In this study, ketamine use was not associated with improvement in ventilatory variables associated with bronchospasm." | 3.96 | Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020) |
| "A 75-year-old male diagnosed to be a case of intractable asthma resistant to all conventional therapies requiring ventilatory support, was successfully weaned off the ventilator after treatment with subanaesthetic dose of intravenous ketamine." | 3.77 | Subanaesthetic dose of ketamine in intractable asthma. ( Garg, D; Kaistha, S; Sood, D, 2011) |
| "This case suggests that intravenous ketamine given in a dissociative dose may be an effective temporizing measure to avoid mechanical ventilation in adult patients with severe asthma exacerbations." | 3.77 | Intravenous ketamine in a dissociating dose as a temporizing measure to avoid mechanical ventilation in adult patient with severe asthma exacerbation. ( Hawthorne, T; Shlamovitz, GZ, 2011) |
| " In the present results, ayanin did not affect xylazine/ketamine-induced anesthesia, suggesting that ayanin has few or no adverse effects, such as nausea, vomiting, and gastric hypersecretion." | 3.76 | Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia. ( Chen, CM; Ko, WC; Lee, FP; Shen, HY; Shih, CM, 2010) |
| "Both inhalation and systemic administration of ketamine attenuate inflammatory the lung injury and airway hyperreactivity of the OVA-induced asthma model." | 3.74 | [Protective effects of ketamine on allergen-induced airway inflammatory injure and high airway reactivity in asthma: experiment with rats]. ( Ding, ZN; Fu, CZ; Qian, YN; Rong, HB; Xu, YM; Zhu, MM; Zhu, W, 2007) |
| " Anesthesia was induced with propofol and ketamine under the Sellick maneuver." | 3.70 | [Bronchospasm during crush induction with propofol under the Sellick maneuver in a patient for emergency laparotomy]. ( Doi, K; Saito, Y; Sato, K; Yamada, Y; Yamamori, Y, 1999) |
| "This paper presents preliminary estimation of clinical usefulness of isoflurane for treatment of severe cases of status asthmaticus in children and application of it as monoanesthesia in children with bronchial asthma, operated upon sudden indications." | 3.69 | [Use of inhalation anesthetics in treatment of severe status asthmaticus and for anesthesia in children suffering from bronchial asthma. Preliminary report]. ( Bujok, G; Kudła, M; Sada-Cieślar, M, 1995) |
| "Two patients with acute severe asthma, who failed to respond to conventional therapy, were given intravenous ketamine in sub-anaesthetic doses with good results." | 3.68 | Use of ketamine in acute severe asthma. ( Sarma, VJ, 1992) |
| "In vitro preparations of trachea isolated from normal and asthmatic guinea pigs were used to measure their maximum contractile response to histamine challenge and to determine spontaneous relaxation of smooth muscle of the airway." | 3.66 | Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs. ( Aldrete, JA; Cabanas, A; Souhrada, JF, 1980) |
| " We found a large heterogeneity regarding sample size, age and gender distribution, inclusion criteria (different severity scores, if any) and ketamine dosing (bolus and/or continuous infusion)." | 2.82 | Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies. ( Astuto, M; Brancati, S; Crimi, C; Cuttone, G; Dezio, V; Falcone, M; La Via, L; Sanfilippo, F, 2022) |
| " After long-term use as a dissociative anesthetic, it has re-emerged as a useful agent for ameliorating pain, asthmaticus, and depression." | 2.50 | Ketamine-an update on its clinical uses and abuses. ( Lei, H; Xu, J, 2014) |
| "Ketamine was introduced into clinical anaesthesia in 1965." | 2.38 | [Ketamine as a broncholytic agent in status asthmaticus and as an anesthetic for patients with bronchial asthma]. ( Jørgensen, BG, 1992) |
| "Ketamine was given IV with a rapid fall in pCO2." | 1.27 | The use of ketamine for the emergency intubation of patients with status asthmaticus. ( Arens, JJ; L'Hommedieu, CS, 1987) |
| "Ketamine appears to increase catecholamine levels and directly relax bronchial smooth muscle." | 1.27 | Use of ketamine in asthmatic children to treat respiratory failure refractory to conventional therapy. ( L'Hommedieu, CS; Reyes de la Rocha, S; Rock, MJ; Truemper, E, 1986) |
| "Ketamine is a useful drug in the intensive treatment of status asthmaticus and should be tried before a decision is taken to start mechanical ventilation." | 1.27 | Ketamine by continuous infusion in status asthmaticus. ( Hallam, PL; Strube, PJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (23.40) | 18.7374 |
| 1990's | 12 (25.53) | 18.2507 |
| 2000's | 7 (14.89) | 29.6817 |
| 2010's | 12 (25.53) | 24.3611 |
| 2020's | 5 (10.64) | 2.80 |
| Authors | Studies |
|---|---|
| Garner, O | 1 |
| Ramey, JS | 1 |
| Hanania, NA | 1 |
| Calleja-Alarcón, S | 1 |
| Sánchez-Hurtado, LA | 1 |
| Romero-Gutiérrez, L | 1 |
| Guerrero-Escobar, JC | 1 |
| Ávila-García, JE | 1 |
| La Via, L | 1 |
| Sanfilippo, F | 1 |
| Cuttone, G | 1 |
| Dezio, V | 1 |
| Falcone, M | 1 |
| Brancati, S | 1 |
| Crimi, C | 1 |
| Astuto, M | 1 |
| Xiao, S | 1 |
| Zhou, Y | 4 |
| Wang, Q | 3 |
| Yang, D | 2 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 3 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 2 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 5 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 6 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 1 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Efficacy for Acute Severe Bronchospasm in Mechanically Ventilated-critically Ill Patients: a Randomized Controlled Trial[NCT03000413] | Phase 2/Phase 3 | 90 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | ||
| Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study)[NCT04427605] | 57 participants (Actual) | Observational | 2019-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for ketamine and Asthma
| Article | Year |
|---|---|
Management of Life-Threatening Asthma: Severe Asthma Series.
Topics: Adrenal Cortex Hormones; Asthma; Humans; Ketamine; Magnesium Sulfate; Muscarinic Antagonists; Propof | 2022 |
Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies.
Topics: Adrenal Cortex Hormones; Adult; Aminophylline; Anti-Asthmatic Agents; Asthma; Child; Cholinergic Ant | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Management of acute asthma in the pediatric patient: an evidence-based review.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anesthetics, Dissociative; Asthma; Blood Gas Anal | 2013 |
Ketamine-an update on its clinical uses and abuses.
Topics: Analgesics; Animals; Asthma; Depressive Disorder, Major; Gastrointestinal Tract; Humans; Ketamine; P | 2014 |
Ketamine for management of acute exacerbations of asthma in children.
Topics: Acute Disease; Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Disease Progressi | 2012 |
Acute asthma in emergency room.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Adrenergic beta-Agonists; Aminophyl | 2003 |
Continuous ketamine infusion for the treatment of refractory asthma in a mechanically ventilated infant: case report and review of the pediatric literature.
Topics: Adolescent; Anesthetics, Dissociative; Asthma; Child; Child, Preschool; Combined Modality Therapy; H | 1996 |
[Applicability of intravenous anesthesia--special reference to propofol and ketamine].
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenou | 1999 |
Does ketamine have a role in managing severe exacerbation of asthma in adults?
Topics: Adult; Asthma; Excitatory Amino Acid Antagonists; Humans; Ketamine; Randomized Controlled Trials as | 2001 |
[Ketamine as a broncholytic agent in status asthmaticus and as an anesthetic for patients with bronchial asthma].
Topics: Animals; Asthma; Bronchodilator Agents; Humans; Ketamine; Lung; Status Asthmaticus | 1992 |
3 trials available for ketamine and Asthma
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma.
Topics: Adolescent; Anesthetics, Dissociative; Asthma; Bronchodilator Agents; Child; Child, Preschool; Doubl | 2005 |
The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma.
Topics: Adolescent; Anesthetics, Dissociative; Asthma; Bronchodilator Agents; Child; Child, Preschool; Doubl | 2005 |
The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma.
Topics: Adolescent; Anesthetics, Dissociative; Asthma; Bronchodilator Agents; Child; Child, Preschool; Doubl | 2005 |
The efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma.
Topics: Adolescent; Anesthetics, Dissociative; Asthma; Bronchodilator Agents; Child; Child, Preschool; Doubl | 2005 |
Randomized, double-blind, placebo-controlled trial of intravenous ketamine in acute asthma.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Dissociative; Asthma; Bronchodilator Age | 1996 |
34 other studies available for ketamine and Asthma
| Article | Year |
|---|---|
[Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report].
Topics: Anaphylaxis; Asthma; Bronchial Spasm; Female; Humans; Ketamine; Midazolam | 2022 |
Ketamine Attenuates Airway Inflammation via Inducing Inflammatory Cells Apoptosis and Activating Nrf2 Pathway in a Mixed-Granulocytic Murine Asthma Model.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation; Kelch-Like ECH- | 2022 |
Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial.
Topics: Aged; Airway Resistance; Analgesics, Opioid; Anesthetics, Dissociative; Asthma; Bronchial Spasm; Bro | 2020 |
Nebulized ketamine to avoid mechanical ventilation in a pediatric patient with severe asthma exacerbation.
Topics: Asthma; Bronchodilator Agents; Child, Preschool; Disease Progression; Emergency Service, Hospital; F | 2018 |
MTOR-Mediated Autophagy Is Involved in the Protective Effect of Ketamine on Allergic Airway Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Autophagy; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2019 |
Is ketamine effective for the management of acute asthma exacerbations in children?
Topics: Asthma; Bronchodilator Agents; Humans; Ketamine | 2014 |
Ketamine for status asthmaticus with respiratory failure.
Topics: Anesthetics, Dissociative; Asthma; Female; Humans; Ketamine | 2014 |
Ketamine Inhalation Ameliorates Ovalbumin-Induced Murine Asthma by Suppressing the Epithelial-Mesenchymal Transition.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epi | 2016 |
Intravenous ketamine in a dissociating dose as a temporizing measure to avoid mechanical ventilation in adult patient with severe asthma exacerbation.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Asthma; Disease Progression; Female; Huma | 2011 |
Ayanin, a non-selective phosphodiesterase 1-4 inhibitor, effectively suppresses ovalbumin-induced airway hyperresponsiveness without affecting xylazine/ketamine-induced anesthesia.
Topics: Anesthesia; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Female; Flavonoids; Hypersensi | 2010 |
Subanaesthetic dose of ketamine in intractable asthma.
Topics: Aged; Anesthetics, Dissociative; Asthma; Bronchial Spasm; Drug Repositioning; Drug Resistance, Multi | 2011 |
Airway management in acute respiratory distress secondary to tracheal stenosis following one time intubation.
Topics: Adolescent; Analgesics; Anesthesia, Inhalation; Anesthetics, Local; Asthma; Emergency Treatment; Fib | 2004 |
Regional variation in ICU care for pediatric patients with asthma.
Topics: Anti-Asthmatic Agents; Asthma; Child; Cohort Studies; Critical Care; Excitatory Amino Acid Antagonis | 2005 |
Ketamine to avoid mechanical ventilation in severe pediatric asthma.
Topics: Anesthetics, Dissociative; Asthma; Child; Child, Preschool; Humans; Infusions, Intravenous; Ketamine | 2006 |
[Protective effects of ketamine on allergen-induced airway inflammatory injure and high airway reactivity in asthma: experiment with rats].
Topics: Airway Resistance; Allergens; Animals; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchi | 2007 |
[Postoperative asthmaticus status controlled with ketamine (author's transl)].
Topics: Asthma; Humans; Ketamine; Male; Middle Aged; Postoperative Complications | 1981 |
Effects of ketamine and halothane on normal and asthmatic smooth muscle of the airway in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Halo | 1980 |
[Use of inhalation anesthetics in treatment of severe status asthmaticus and for anesthesia in children suffering from bronchial asthma. Preliminary report].
Topics: Administration, Inhalation; Adolescent; Anesthesia, Inhalation; Asthma; Bronchi; Child; Child, Presc | 1995 |
Exaggerated psychomotor response to intravenous bolus dose administration of ketamine.
Topics: Adult; Akathisia, Drug-Induced; Asthma; Female; Humans; Injections, Intravenous; Ketamine; Uterine H | 1994 |
Ketamine infusion for postoperative analgesia: a prospective cohort study in asthmatics.
Topics: Adult; Analgesia; Asthma; Cohort Studies; Diazepam; Female; Humans; Infusions, Intravenous; Ketamine | 1993 |
Ketamine infusion for postoperative analgesia in asthmatics: a comparison with intermittent meperidine.
Topics: Adult; Asthma; Bronchial Spasm; Female; Humans; Hysterectomy; Infusions, Intravenous; Ketamine; Mepe | 1993 |
Efficacy of ketamine infusion in refractory asthma complicated by acute myocardial infarction.
Topics: Asthma; Bronchial Spasm; Conscious Sedation; Female; Humans; Infusions, Intravenous; Ketamine; Midaz | 1993 |
[Ketanest in bronchial asthma].
Topics: Anesthetics, Dissociative; Asthma; Drug Therapy, Combination; Humans; Ketamine; Status Asthmaticus | 1998 |
[Bronchospasm during crush induction with propofol under the Sellick maneuver in a patient for emergency laparotomy].
Topics: Anesthesia; Asthma; Bronchial Spasm; Emergencies; Humans; Intestinal Obstruction; Intubation, Intrat | 1999 |
Ketamine block of bronchospasm in experimental canine asthma.
Topics: Airway Resistance; Anesthesia, Intravenous; Animals; Antigens; Ascaris; Asthma; Bronchial Spasm; Dis | 1979 |
[Physio-pathological considerations and clinical contribution on the use of ketamine-pancuronium combination in the anesthesia of an asthmatic patient].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Asthma; Child; Drug Synergism; Female; Humans; Ketamin | 1975 |
Use of ketamine in acute severe asthma.
Topics: Adult; Asthma; Bronchial Spasm; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Ket | 1992 |
Ketamine in acute asthma.
Topics: Acute Disease; Asthma; Humans; Ketamine | 1985 |
[Ketamine in the treatment of severe therapy-resistant status asthmaticus].
Topics: Asthma; Child; Female; Humans; Infant; Ketamine; Status Asthmaticus | 1988 |
[Status asthmaticus treated with ketamine].
Topics: Asthma; Humans; Ketamine; Male; Middle Aged; Status Asthmaticus | 1987 |
The use of ketamine for the emergency intubation of patients with status asthmaticus.
Topics: Asthma; Emergencies; Female; Hemodynamics; Humans; Infant; Intubation, Intratracheal; Ketamine; Kine | 1987 |
Use of ketamine in asthmatic children to treat respiratory failure refractory to conventional therapy.
Topics: Acute Disease; Adolescent; Asthma; Child; Child, Preschool; Combined Modality Therapy; Drug Therapy, | 1986 |
Ketamine by continuous infusion in status asthmaticus.
Topics: Adolescent; Asthma; Critical Care; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; | 1986 |
Ketamine: its effect on airway resistance in man.
Topics: Airway Resistance; Anesthesia, General; Asthma; Bronchial Spasm; Humans; Ketamine; Lung Compliance | 1972 |