Page last updated: 2024-10-29

ketamine and Arthritis, Degenerative

ketamine has been researched along with Arthritis, Degenerative in 4 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"The study evaluated the effect of intra-articular injections of ketamine and 25% dextrose with triamcinolone acetate (TA) and hyaluronic acid (HA) on joint pathology and pain behavior in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in experimental mice."7.85Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis. ( Brahma, S; Jalgaonkar, SV; Koli, PG; Kshirsagar, S; Patil, AE; Rege, NN; Salgaonkar, S; Shetty, YC; Teltumbde, PA, 2017)
"The aim of the present study was to investigate the efficacy of ketamine in attenuating osteoarthritis (OA) and modulating the expression of inflammatory mediators."7.83Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model. ( Lu, W; Wang, L; Wo, C; Yao, J, 2016)
" Osteoarthritis was induced in male adult control Wistar rats without any interventions and in Wisket rats after juvenile social isolation and ketamine treatment."3.96Distinct changes in chronic pain sensitivity and oxytocin receptor expression in a new rat model (Wisket) of schizophrenia. ( Banki, L; Büki, A; Horvath, G; Jancsó, G; Kekesi, G; Kis, G; Somogyvári, F; Tuboly, G; Varga, E; Vécsei, L, 2020)
"The study evaluated the effect of intra-articular injections of ketamine and 25% dextrose with triamcinolone acetate (TA) and hyaluronic acid (HA) on joint pathology and pain behavior in monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in experimental mice."3.85Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis. ( Brahma, S; Jalgaonkar, SV; Koli, PG; Kshirsagar, S; Patil, AE; Rege, NN; Salgaonkar, S; Shetty, YC; Teltumbde, PA, 2017)
"The aim of the present study was to investigate the efficacy of ketamine in attenuating osteoarthritis (OA) and modulating the expression of inflammatory mediators."3.83Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model. ( Lu, W; Wang, L; Wo, C; Yao, J, 2016)
"Our report describes for the first time the continuous long-term intrathecal application of S(+)-ketamine in a patient with chronic pain and morphine tolerance."3.71The long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance. ( Deusch, E; Kress, HG; Maier, P; Sator-Katzenschlager, S; Spacek, A, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Banki, L1
Büki, A1
Horvath, G1
Kekesi, G1
Kis, G1
Somogyvári, F1
Jancsó, G1
Vécsei, L1
Varga, E1
Tuboly, G1
Shetty, YC1
Patil, AE1
Jalgaonkar, SV1
Rege, NN1
Salgaonkar, S1
Teltumbde, PA1
Kshirsagar, S1
Koli, PG1
Brahma, S1
Lu, W1
Wang, L1
Wo, C1
Yao, J1
Sator-Katzenschlager, S1
Deusch, E1
Maier, P1
Spacek, A1
Kress, HG1

Other Studies

4 other studies available for ketamine and Arthritis, Degenerative

ArticleYear
Distinct changes in chronic pain sensitivity and oxytocin receptor expression in a new rat model (Wisket) of schizophrenia.
    Neuroscience letters, 2020, 01-01, Volume: 714

    Topics: Analgesics, Opioid; Animals; Ankle Joint; Brain; Brain Stem; Chronic Pain; Diencephalon; Disease Mod

2020
Intra-articular injections of ketamine and 25% dextrose improve clinical and pathological outcomes in the monosodium iodoacetate model of osteoarthritis.
    Journal of basic and clinical physiology and pharmacology, 2017, Nov-27, Volume: 28, Issue:6

    Topics: Animals; Arthritis, Experimental; Behavior, Animal; Drug Therapy, Combination; Glucose; Hyaluronic A

2017
Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model.
    Molecular medicine reports, 2016, Volume: 13, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent As

2016
The long-term antinociceptive effect of intrathecal S(+)-ketamine in a patient with established morphine tolerance.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:4

    Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Back Pain; Drug Tolerance; Female; Humans

2001