Page last updated: 2024-10-29

ketamine and Arrhythmias, Cardiac

ketamine has been researched along with Arrhythmias, Cardiac in 40 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"To investigate the influence of thiopental (85 mg/kg, intraperitoneally (ip)), and ketamine+xylazine (ketamine 75 mg/kg and xylazine 8 mg/kg, ip) anesthesia on the incidence and duration of ischemia/reperfusion-induced arrhythmias."7.81Comparison of thiopental and ketamine+xylazine anesthesia in ischemia/reperfusion-induced arrhythmias in rats. ( Gonca, E, 2015)
" The present study presents a new model system in which the higher cerebral centers are blocked chemically (ketamine inhibition of N-methyl-D-aspartate receptors) and the system is perturbed over a longer 15-min interval by continuous hemorrhage."7.70Nonlinear dynamics of heart rate variability during experimental hemorrhage in ketamine-anesthetized rats. ( Dalsey, WC; Nester, BA; Skinner, JE, 2000)
"The purpose of this study was to examine the effects of pharmacologic alterations of adrenergic terminating mechanisms by cocaine, tropolone, aminophylline, and ketamine on the ability of epinephrine to induce arrhythmias during halothane-nitrous oxide anesthesia in dogs."7.65Effects of pharmacologic alterations of adrenergic mechanisms by cocaine, tropolone, aminophylline, and ketamine on epinephrine-induced arrhythmias during halothane-nitrous oxide anesthesia. ( Koehntop, DE; Liao, JC; Van Bergen, FH, 1977)
"Ketamine was cardiovascular depressant at high concentration, and this effect could account in part for the antiarrhythmic action of ketamine in this condition."5.28[The effect of ketamine on epinephrine-induced arrhythmias in dogs anesthetized with halothane-nitrous oxide]. ( Niiya, S, 1990)
"To investigate the influence of thiopental (85 mg/kg, intraperitoneally (ip)), and ketamine+xylazine (ketamine 75 mg/kg and xylazine 8 mg/kg, ip) anesthesia on the incidence and duration of ischemia/reperfusion-induced arrhythmias."3.81Comparison of thiopental and ketamine+xylazine anesthesia in ischemia/reperfusion-induced arrhythmias in rats. ( Gonca, E, 2015)
"We have investigated the effects of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrogen maleate (MK801), a non-competitive N-methyl-D-aspartate (NMDA) ionotropic excitatory amino acid receptor antagonist, and 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), a non-NMDA ionotropic excitatory amino acid receptor antagonist, ketamine and memantine, NMDA receptor channel blockers, on ventricular arrhythmias induced by myocardial ischaemia and myocardial ischaemia-reperfusion."3.70Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists. ( D'Amico, M; Di Filippo, C; Rossi, F, 1999)
" The present study presents a new model system in which the higher cerebral centers are blocked chemically (ketamine inhibition of N-methyl-D-aspartate receptors) and the system is perturbed over a longer 15-min interval by continuous hemorrhage."3.70Nonlinear dynamics of heart rate variability during experimental hemorrhage in ketamine-anesthetized rats. ( Dalsey, WC; Nester, BA; Skinner, JE, 2000)
"8 g/kg), and a contribution of diazepam with ketamine hydrochloride (D+K, 10 + 100 mg/kg) anesthesia on the incidence of ischemia/ reperfusion-induced arrhythmias in rats."3.69Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats. ( Baczkó, I; Leprán, I; Papp, JG, 1997)
"The induction of halothane anesthesia following intravenous administration of aminophylline may cause ventricular arrhythmias."3.66Cardiovascular effects of ketamine following administration of aminophylline in dogs. ( Berger, JM; Ricker, SM; Roe, SD; Stirt, JA; Sullivan, SF, 1982)
"The purpose of this study was to examine the effects of pharmacologic alterations of adrenergic terminating mechanisms by cocaine, tropolone, aminophylline, and ketamine on the ability of epinephrine to induce arrhythmias during halothane-nitrous oxide anesthesia in dogs."3.65Effects of pharmacologic alterations of adrenergic mechanisms by cocaine, tropolone, aminophylline, and ketamine on epinephrine-induced arrhythmias during halothane-nitrous oxide anesthesia. ( Koehntop, DE; Liao, JC; Van Bergen, FH, 1977)
"The regulation of intraocular pressure is important for successful ophthalmic surgery and can be greatly affected by the anesthetic procedure."2.36Anesthesia in ophthalmic surgery. ( Brunson, DB, 1980)
"Cardiac arrhythmias were observed in 21 (53·8%) dogs."1.40Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012). ( Monteiro-Steagall, BP; Ramos, RV; Steagall, PV, 2014)
"Convulsive seizures triggered by maximal electroshock (MES) induce profound abnormalities in neural regulation of cardiac rhythm that are manifested by a period of marked cardiac arrhythmia in the immediate postictal state."1.32Effects of seizure severity and seizure repetition on postictal cardiac arrhythmia following maximal electroshock. ( Casebeer, D; Darbin, O; Naritoku, DK, 2003)
"Finally, no arrhythmia could be induced regardless of the ketamine concentration."1.30Effects of ketamine on ventricular conduction, refractoriness, and wavelength: potential antiarrhythmic effects: a high-resolution epicardial mapping in rabbit hearts. ( Aya, AG; Bruelle, P; de La Coussaye, JE; Eledjam, JJ; Juan, JM; Lefrant, JY; Peray, P; Robert, E, 1997)
"Ketamine was cardiovascular depressant at high concentration, and this effect could account in part for the antiarrhythmic action of ketamine in this condition."1.28[The effect of ketamine on epinephrine-induced arrhythmias in dogs anesthetized with halothane-nitrous oxide]. ( Niiya, S, 1990)
"Epinephrine-induced arrhythmias were studied in 4 cats (group A), using a 4 X 4 Latin square design."1.27Ketamine and the arrhythmogenic dose of epinephrine in cats anesthetized with halothane and isoflurane. ( Bednarski, RM; Majors, LJ, 1986)
"Ketamine, ketamine-xylazine, and ketamine-diazepam were evaluated clinically in 15 ferrets, and safe dosage was determined for each."1.27Evaluation of ketamine, ketamine-xylazine and ketamine-diazepam anesthesia in the ferret. ( Glaser, C; Moreland, AF, 1985)
"Malignant hyperthermia is an autosomal dominant disorder occurring mainly with the administration of halogenated fluoroethane and depolarizing muscle relaxants."1.25Current trends in ophthalmic anesthesia. The Second Walter S. Atkinson Lecture. ( Newell, FW, 1975)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199019 (47.50)18.7374
1990's9 (22.50)18.2507
2000's4 (10.00)29.6817
2010's8 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wiemer, HM1
Butler, MB1
Froese, PC1
Lapierre, A1
Carriere, C1
Etsell, GR1
Farina, D1
Jones, J1
Murray, J1
Campbell, SG1
Ramos, RV1
Monteiro-Steagall, BP1
Steagall, PV1
Espahbodi, E1
Sanatkar, M1
Sadrossadat, H1
Darabi Vafsi, ME1
Azarshahin, M1
Shoroughi, M1
Shekarforoush, S1
Fatahi, Z1
Safari, F1
Altunkaynak, HO1
Tecder-Unal, M1
Gonca, E1
Chatzidaki, R1
Koraki, E1
Vasiliadis, K1
Aslanidis, T1
Vasilakos, D1
Mikesell, CE1
Atkinson, DE1
Rachman, BR1
Wu, J1
Zhang, Y1
Zhang, X1
Cheng, L1
Lammers, WJ1
Grace, AA1
Fraser, JA1
Zhang, H1
Huang, CL1
Lei, M1
Darbin, O1
Casebeer, D1
Naritoku, DK1
Arican, FO1
Okan, T1
Badak, O1
Guneri, S1
Brunson, DB1
Stirt, JA1
Berger, JM1
Roe, SD1
Ricker, SM1
Sullivan, SF1
Barrigon, S1
De Miguel, B1
Tamargo, J1
Tejerina, T1
Topkins, MJ1
Filippelli, A1
Cuparencu, B1
Falciani, M1
de Novellis, V1
Safta, L1
Arustei, V1
Rossi, F3
Krissel, J1
Dick, WF1
Leyser, KH1
Gervais, H1
Brockerhoff, P1
Schranz, D1
Crambes, A1
Monassier, L1
Chapleau, D1
Roegel, JC1
Feldman, J1
Bousquet, P1
Baczkó, I1
Leprán, I1
Papp, JG1
Aya, AG1
Robert, E1
Bruelle, P1
Lefrant, JY1
Juan, JM1
Peray, P1
Eledjam, JJ1
de La Coussaye, JE1
D'Amico, M1
Di Filippo, C1
Lychakov, AV1
Petrov, AN1
Shevchuk, MK1
Skinner, JE1
Nester, BA1
Dalsey, WC1
Koehntop, DE1
Liao, JC1
Van Bergen, FH1
Reves, JG1
Lell, WA1
McCracken, LE1
Kravetz, RA1
Prough, DS1
ApIvor, D1
Ravi, PK1
Little, L1
Beltrami, M1
Canevazzi, P1
Frassinetti, E1
Newell, FW1
Schumann, R1
Niiya, S1
Sears, DH1
Abdul-Rasool, IH1
Katz, RL1
Bednarski, RM2
Sams, RA1
Majors, LJ2
Ashcraft, S1
Faithfull, NS1
Poelman, C1
Dhasmana, KM1
Erdmann, W1
Moreland, AF1
Glaser, C1
Kilmore, MA1
Clark, JP1
Holmes, JA1
Merifield, DO1
Sussman, DR1
Lyons, SM1
Clarke, RS1
Dundee, JW1
Weisman, H1

Reviews

3 reviews available for ketamine and Arrhythmias, Cardiac

ArticleYear
Prolonged QT syndrome and sedation: a case report and a review of the literature.
    Pediatric emergency care, 2011, Volume: 27, Issue:2

    Topics: Arrhythmias, Cardiac; Atenolol; Child, Preschool; Conscious Sedation; Electrocardiography; Emergency

2011
Anesthesia in ophthalmic surgery.
    The Veterinary clinics of North America. Small animal practice, 1980, Volume: 10, Issue:2

    Topics: Analgesics, Opioid; Anesthesia; Anesthesia, Inhalation; Animals; Antipsychotic Agents; Arrhythmias,

1980
Anesthesiology 1970.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 96, Issue:3

    Topics: Adult; Anesthesia, Endotracheal; Anesthesia, General; Anesthesiology; Anesthetics; Arrhythmias, Card

1972

Trials

3 trials available for ketamine and Arrhythmias, Cardiac

ArticleYear
Ketamine or atropine: which one better prevents oculocardiac reflex during eye surgery? A prospective randomized clinical trial.
    Acta medica Iranica, 2015, Volume: 53, Issue:3

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Bradycardia; Child; Child, Preschool; Humans; K

2015
Thiopentone, thiopentone/ketamine, and ketamine for induction of anaesthesia in caesarean section.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apgar Score; Arrhythmias, Cardiac; Awarenes

1994
Comparison of morphine and ketamine anesthetic technics for coronary surgery: a randomized study.
    Southern medical journal, 1978, Volume: 71, Issue:1

    Topics: Adult; Aged; Anesthetics; Arrhythmias, Cardiac; Diazepam; Hemodynamics; Humans; Hypertension; Ketami

1978

Other Studies

34 other studies available for ketamine and Arrhythmias, Cardiac

ArticleYear
Procedural sedation by advanced care paramedics for emergency gastrointestinal endoscopy.
    CJEM, 2019, Volume: 21, Issue:2

    Topics: Allied Health Personnel; Analgesics; Arrhythmias, Cardiac; Datasets as Topic; Emergency Service, Hos

2019
Management and complications of anaesthesia during balloon valvuloplasty for pulmonic stenosis in dogs: 39 cases (2000 to 2012).
    The Journal of small animal practice, 2014, Volume: 55, Issue:4

    Topics: Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Arrhythmias, Card

2014
The effects of pentobarbital, ketamine-pentobarbital and ketamine-xylazine anesthesia in a rat myocardial ischemic reperfusion injury model.
    Laboratory animals, 2016, Volume: 50, Issue:3

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Hemodynamics; Ketamine; Male; Myocardial Reperfusion Inj

2016
The role of mitochondrial ATP-sensitive potassium channels on cardiovascular effects of thiopental and ketamine in rats.
    Bratislavske lekarske listy, 2015, Volume: 116, Issue:9

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Arterial Pressur

2015
Comparison of thiopental and ketamine+xylazine anesthesia in ischemia/reperfusion-induced arrhythmias in rats.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:6

    Topics: Anesthetics, Combined; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Blood Pressure; Hear

2015
Appendectomy for an adult with cyanotic congenital heart disease.
    Minerva anestesiologica, 2009, Volume: 75, Issue:4

    Topics: Androstanols; Anesthesia, Intravenous; Appendectomy; Appendicitis; Arrhythmias, Cardiac; Contraindic

2009
Altered sinoatrial node function and intra-atrial conduction in murine gain-of-function Scn5a+/ΔKPQ hearts suggest an overlap syndrome.
    American journal of physiology. Heart and circulatory physiology, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Algorithms; Anesthesia; Anesthetics, Dissociative; Animals; Arrhythmias, Cardiac; Atrioventricular N

2012
Effects of seizure severity and seizure repetition on postictal cardiac arrhythmia following maximal electroshock.
    Experimental neurology, 2003, Volume: 181, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Disease Progression; Electrocardiography; Electrodes, Implanted; Elec

2003
An unusual presentation from xylazine-ketamine.
    Veterinary and human toxicology, 2004, Volume: 46, Issue:6

    Topics: Adult; Anesthetics; Arrhythmias, Cardiac; Diagnosis, Differential; Electrocardiography; Humans; Keta

2004
Cardiovascular effects of ketamine following administration of aminophylline in dogs.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:8

    Topics: Aminophylline; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Dogs; Drug Interaction

1982
The mechanism of the positive inotropic action of ketamine on isolated atria of the rat.
    British journal of pharmacology, 1982, Volume: 76, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Drug Interactions; Heart Rate; In Vitro Techniques; Ketamine

1982
Anesthetic management of cardiac catheterization.
    International anesthesiology clinics, 1980,Spring, Volume: 18, Issue:1

    Topics: Adolescent; Anesthesia; Arrhythmias, Cardiac; Cardiac Catheterization; Child; Child, Preschool; Huma

1980
Effects of the intracerebroventricular administration of ketamine on centrogenic arrhythmias in anesthetized rats.
    Research communications in chemical pathology and pharmacology, 1994, Volume: 84, Issue:3

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Aspartic Acid; Cerebral Ventricles; Desipramine; Electroc

1994
GABAergic and glutaminergic modulation of centrally evoked arrhythmias in rats.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Baclofen; Brain; Cardiovascular System; Electric Stimulation; GABA Ag

1996
Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:2

    Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Death, Sudden; Diazepam; Hemodynamics; Ketamine; Male; M

1997
Effects of ketamine on ventricular conduction, refractoriness, and wavelength: potential antiarrhythmic effects: a high-resolution epicardial mapping in rabbit hearts.
    Anesthesiology, 1997, Volume: 87, Issue:6

    Topics: Anesthetics, Dissociative; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Rela

1997
Arrhythmias induced by myocardial ischaemia-reperfusion are sensitive to ionotropic excitatory amino acid receptor antagonists.
    European journal of pharmacology, 1999, Feb-05, Volume: 366, Issue:2-3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arrhythmias, Cardiac; Blood Pressure; Dizocilpine Mal

1999
[Effects of arginyl-vasopressin on various heart arrhythmias].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:3

    Topics: Aconitine; Amphetamine; Animals; Anti-Arrhythmia Agents; Arginine Vasopressin; Arrhythmias, Cardiac;

1999
Nonlinear dynamics of heart rate variability during experimental hemorrhage in ketamine-anesthetized rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Anesthesia; Anesthetics, Dissociative; Animals; Arrhythmias, Cardiac; Electrocardiography; Forecasti

2000
Effects of pharmacologic alterations of adrenergic mechanisms by cocaine, tropolone, aminophylline, and ketamine on epinephrine-induced arrhythmias during halothane-nitrous oxide anesthesia.
    Anesthesiology, 1977, Volume: 46, Issue:2

    Topics: Aminophylline; Anesthesia, Endotracheal; Animals; Arrhythmias, Cardiac; Blood Pressure; Cocaine; Cyc

1977
Cardiac effects of intravenous atropine. Electrocardiographic studies during ketamine anaesthesia.
    Anaesthesia, 1978, Volume: 33, Issue:6

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Electrocardiography; H

1978
[Effect of ketamine on cardiac excitation and conduction].
    Minerva anestesiologica, 1978, Volume: 44, Issue:11

    Topics: Aged; Arrhythmias, Cardiac; Female; Heart Conduction System; Humans; Ketamine; Male; Neuroleptanalge

1978
Current trends in ophthalmic anesthesia. The Second Walter S. Atkinson Lecture.
    Ophthalmic surgery, 1975,Summer, Volume: 6, Issue:2

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Evaluation Studies as Topic; Humans; Ketamine; Malignant

1975
Xylazine is known to cause arrhythmias in several species.
    Laboratory animal science, 1992, Volume: 42, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Ketamine; Xylazine

1992
[The effect of ketamine on epinephrine-induced arrhythmias in dogs anesthetized with halothane-nitrous oxide].
    Masui. The Japanese journal of anesthesiology, 1990, Volume: 39, Issue:12

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Drug Synergism; Epinephrine; Halothane;

1990
The effect of a second dose of succinylcholine on cardiac rate and rhythm following induction of anesthesia with ketamine.
    Anesthesiology, 1988, Volume: 68, Issue:4

    Topics: Adult; Anesthesia; Arrhythmias, Cardiac; Humans; Ketamine; Middle Aged; Succinylcholine

1988
Reduction of the ventricular arrhythmogenic dose of epinephrine by ketamine administration in halothane-anesthetized cats.
    American journal of veterinary research, 1988, Volume: 49, Issue:3

    Topics: Analysis of Variance; Anesthesia; Animals; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure;

1988
Ketamine-induced dysrhythmia and its antagonism: a case report.
    European journal of anaesthesiology, 1987, Volume: 4, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Ketamine; Mitral Valve Prolapse

1987
Ketamine and the arrhythmogenic dose of epinephrine in cats anesthetized with halothane and isoflurane.
    American journal of veterinary research, 1986, Volume: 47, Issue:10

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Cats; Dose-Response Relationship, Drug; Epinephrine; Halo

1986
Evaluation of ketamine, ketamine-xylazine and ketamine-diazepam anesthesia in the ferret.
    Laboratory animal science, 1985, Volume: 35, Issue:3

    Topics: Anesthesia, General; Animals; Animals, Laboratory; Arrhythmias, Cardiac; Carnivora; Diazepam; Electr

1985
Effect of ketamine on myocardial irritability.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardi

1974
A comparative evaluation of ketamine anesthesia in children and adults.
    Anesthesiology, 1974, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Age Factors; Airway Obstruction; Analgesia; Anesthesia, General; Anesthesia, Intr

1974
Some cardiovascular and respiratory effects of four non-barbiturate anaesthetic induction agents.
    European journal of clinical pharmacology, 1974, Jul-26, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pr

1974
Anesthesia for pediatric ophthalmology.
    Annals of ophthalmology, 1971, Volume: 3, Issue:3

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Dissociative; Arrhythmias, Cardiac; Barbit

1971