Page last updated: 2024-10-29

ketamine and Anxiety, Separation

ketamine has been researched along with Anxiety, Separation in 9 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Anxiety, Separation: Anxiety experienced by an individual upon separation from a person or object of particular significance to the individual.

Research Excerpts

ExcerptRelevanceReference
" However, various dosing regimens when used alone or in combination have variable efficacy and side effect profile."2.71Comparative evaluation of midazolam and ketamine with midazolam alone as oral premedication. ( Chari, P; Ghai, B; Grandhe, RP; Kumar, A, 2005)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdel-Ghaffar, HS1
Kamal, SM1
El Sherif, FA1
Mohamed, SA1
Damle, SG1
Gandhi, M1
Laheri, V1
Wang, X1
Zhou, ZJ1
Zhang, XF1
Zheng, S1
Ghai, B1
Grandhe, RP1
Kumar, A1
Chari, P1
Horiuchi, T1
Kawaguchi, M1
Kurehara, K1
Kawaraguchi, Y1
Sasaoka, N1
Furuya, H1
Bhatt, S1
Neupane, B1
Diaz, JH1
Beebe, DS1
Belani, KG1
Chang, PN1
Hesse, PS1
Schuh, JS1
Liao, JC1
Palahniuk, RJ1
Gutstein, HB1
Johnson, KL1
Heard, MB1
Gregory, GA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Premedication With Different Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children[NCT02935959]Phase 1/Phase 290 participants (Actual)Interventional2016-10-31Completed
Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural Sedation: a Randomized Controlled Trial[NCT04822064]70 participants (Anticipated)Interventional2022-09-22Recruiting
Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children: a Randomized Controlled Trial[NCT04820205]136 participants (Anticipated)Interventional2021-09-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

8 trials available for ketamine and Anxiety, Separation

ArticleYear
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of nebulised dexmedetomidine, ketamine, or midazolam for premedication in preschool children undergoing bone marrow biopsy.
    British journal of anaesthesia, 2018, Volume: 121, Issue:2

    Topics: Administration, Inhalation; Anesthesia Recovery Period; Anxiety, Separation; Bone Marrow Examination

2018
Comparison of oral ketamine and oral midazolam as sedative agents in pediatric dentistry.
    Journal of the Indian Society of Pedodontics and Preventive Dentistry, 2008, Volume: 26, Issue:3

    Topics: Administration, Oral; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anxiety,

2008
A comparison of two different doses of rectal ketamine added to 0.5 mg x kg(-1) midazolam and 0.02 mg x kg(-1) atropine in infants and young children.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:5

    Topics: Administration, Rectal; Anesthetics, Dissociative; Anxiety, Separation; Atropine; Catheterization, C

2010
Comparative evaluation of midazolam and ketamine with midazolam alone as oral premedication.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:7

    Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia Recovery Period; Anesthetics, Dissociative;

2005
Evaluation of relatively low dose of oral transmucosal ketamine premedication in children: a comparison with oral midazolam.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:8

    Topics: Administration, Buccal; Anesthesia, Inhalation; Anesthetics, Dissociative; Anxiety, Separation; Chil

2005
Intranasal ketamine preinduction of paediatric outpatients.
    Paediatric anaesthesia, 1997, Volume: 7, Issue:4

    Topics: Administration, Intranasal; Age Factors; Ambulatory Surgical Procedures; Anesthesia Recovery Period;

1997
Effectiveness of preoperative sedation with rectal midazolam, ketamine, or their combination in young children.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:6

    Topics: Administration, Rectal; Anxiety, Separation; Atropine; Catheterization, Central Venous; Child; Child

1992
Oral ketamine preanesthetic medication in children.
    Anesthesiology, 1992, Volume: 76, Issue:1

    Topics: Administration, Oral; Anxiety, Separation; Child; Child Behavior; Child, Preschool; Double-Blind Met

1992

Other Studies

1 other study available for ketamine and Anxiety, Separation

ArticleYear
Intramuscular ketamine pre-medication to separate children from their parents.
    Nepal Medical College journal : NMCJ, 2005, Volume: 7, Issue:2

    Topics: Anxiety, Separation; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Infant; Injec

2005