ketamine has been researched along with Anterior Choroidal Artery Infarction in 6 studies
Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.
Excerpt | Relevance | Reference |
---|---|---|
"Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption." | 5.46 | Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017) |
" Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)." | 5.17 | Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013) |
"Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption." | 1.46 | Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017) |
"The presence of cerebral hemorrhage after reperfusion was checked macroscopically and infarct volume with 2,3,5-triphenyltetrazolium staining." | 1.30 | Hyperglycemia and the vascular effects of cerebral ischemia. ( Betz, AL; Kawai, N; Keep, RF, 1997) |
"Ketamine was administered as a 50 mg/kg i." | 1.28 | Effects of ketamine on outcome from temporary middle cerebral artery occlusion in the spontaneously hypertensive rat. ( Baker, MT; Ridenour, TR; Todd, MM; Warner, DS, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (50.00) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Von der Brelie, C | 1 |
Seifert, M | 1 |
Rot, S | 1 |
Tittel, A | 1 |
Sanft, C | 1 |
Meier, U | 1 |
Lemcke, J | 1 |
Bleilevens, C | 1 |
Roehl, AB | 1 |
Goetzenich, A | 1 |
Zoremba, N | 1 |
Kipp, M | 1 |
Dang, J | 1 |
Tolba, R | 1 |
Rossaint, R | 1 |
Hein, M | 1 |
Lin, SZ | 1 |
Chiou, AL | 1 |
Wang, Y | 1 |
Kawai, N | 1 |
Keep, RF | 1 |
Betz, AL | 1 |
Chang, ML | 1 |
Yang, J | 1 |
Kem, S | 1 |
Klaidman, L | 1 |
Sugawara, T | 1 |
Chan, PH | 1 |
Adams, JD | 1 |
Ridenour, TR | 1 |
Warner, DS | 1 |
Todd, MM | 1 |
Baker, MT | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Pilot Study of Ketamine Sedation Initiated Early After Aneurysmal Subarachnoid Hemorrhage: Effect on Vasospasm, Delayed Cerebral Ischemia, and Functional Outcomes[NCT05032118] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2023-04-27 | Withdrawn (stopped due to Institution change, no IRB approval) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for ketamine and Anterior Choroidal Artery Infarction
Article | Year |
---|---|
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction; | 2013 |
5 other studies available for ketamine and Anterior Choroidal Artery Infarction
Article | Year |
---|---|
Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics; Cerebral Infarction; Comorbidity; Female; | 2017 |
Ketamine antagonizes nitric oxide release from cerebral cortex after middle cerebral artery ligation in rats.
Topics: Animals; Arginine; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Dizocilpine Maleate; Enz | 1996 |
Hyperglycemia and the vascular effects of cerebral ischemia.
Topics: Anesthetics; Animals; Blood Glucose; Body Temperature; Cerebral Arteries; Cerebral Hemorrhage; Cereb | 1997 |
Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cerebral Infarction; DNA Fragmentation; Excitatory Amino Acid Antagonists; | 2002 |
Effects of ketamine on outcome from temporary middle cerebral artery occlusion in the spontaneously hypertensive rat.
Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; | 1991 |