Page last updated: 2024-10-29

ketamine and Anterior Choroidal Artery Infarction

ketamine has been researched along with Anterior Choroidal Artery Infarction in 6 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
"Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption."5.46Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017)
" Transient MCAO was induced during either isoflurane or ketamine/xylazine (ket/xyl) anesthesia with simultaneously measurement of cerebral blood flow (CBF) in 60 male Wistar rats (380-420 g)."5.17Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model. ( Bleilevens, C; Dang, J; Goetzenich, A; Hein, M; Kipp, M; Roehl, AB; Rossaint, R; Tolba, R; Zoremba, N, 2013)
"Ketamine has neuroprotective characteristics as well as beneficial cardiocirculatory properties and may thus reduce vasopressor consumption."1.46Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia. ( Lemcke, J; Meier, U; Rot, S; Sanft, C; Seifert, M; Tittel, A; Von der Brelie, C, 2017)
"The presence of cerebral hemorrhage after reperfusion was checked macroscopically and infarct volume with 2,3,5-triphenyltetrazolium staining."1.30Hyperglycemia and the vascular effects of cerebral ischemia. ( Betz, AL; Kawai, N; Keep, RF, 1997)
"Ketamine was administered as a 50 mg/kg i."1.28Effects of ketamine on outcome from temporary middle cerebral artery occlusion in the spontaneously hypertensive rat. ( Baker, MT; Ridenour, TR; Todd, MM; Warner, DS, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Von der Brelie, C1
Seifert, M1
Rot, S1
Tittel, A1
Sanft, C1
Meier, U1
Lemcke, J1
Bleilevens, C1
Roehl, AB1
Goetzenich, A1
Zoremba, N1
Kipp, M1
Dang, J1
Tolba, R1
Rossaint, R1
Hein, M1
Lin, SZ1
Chiou, AL1
Wang, Y1
Kawai, N1
Keep, RF1
Betz, AL1
Chang, ML1
Yang, J1
Kem, S1
Klaidman, L1
Sugawara, T1
Chan, PH1
Adams, JD1
Ridenour, TR1
Warner, DS1
Todd, MM1
Baker, MT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Ketamine Sedation Initiated Early After Aneurysmal Subarachnoid Hemorrhage: Effect on Vasospasm, Delayed Cerebral Ischemia, and Functional Outcomes[NCT05032118]Phase 2/Phase 30 participants (Actual)Interventional2023-04-27Withdrawn (stopped due to Institution change, no IRB approval)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ketamine and Anterior Choroidal Artery Infarction

ArticleYear
Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model.
    Experimental brain research, 2013, Volume: 224, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Brain Edema; Brain Injuries; Cerebral Infarction;

2013

Other Studies

5 other studies available for ketamine and Anterior Choroidal Artery Infarction

ArticleYear
Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia.
    World neurosurgery, 2017, Volume: 97

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Analgesics; Cerebral Infarction; Comorbidity; Female;

2017
Ketamine antagonizes nitric oxide release from cerebral cortex after middle cerebral artery ligation in rats.
    Stroke, 1996, Volume: 27, Issue:4

    Topics: Animals; Arginine; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Dizocilpine Maleate; Enz

1996
Hyperglycemia and the vascular effects of cerebral ischemia.
    Stroke, 1997, Volume: 28, Issue:1

    Topics: Anesthetics; Animals; Blood Glucose; Body Temperature; Cerebral Arteries; Cerebral Hemorrhage; Cereb

1997
Nicotinamide and ketamine reduce infarct volume and DNA fragmentation in rats after brain ischemia and reperfusion.
    Neuroscience letters, 2002, Apr-12, Volume: 322, Issue:3

    Topics: Animals; Brain Ischemia; Cerebral Infarction; DNA Fragmentation; Excitatory Amino Acid Antagonists;

2002
Effects of ketamine on outcome from temporary middle cerebral artery occlusion in the spontaneously hypertensive rat.
    Brain research, 1991, Nov-22, Volume: 565, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries;

1991