Page last updated: 2024-10-29

ketamine and Anoxia, Brain

ketamine has been researched along with Anoxia, Brain in 9 studies

Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.

Research Excerpts

ExcerptRelevanceReference
" Here, we focused on the basic physiological effects of ketamine as a recreational drug and its possible interactions with fentanyl-a highly potent opioid that induces strong respiratory depression and robust brain hypoxia."4.31Basic metabolic and vascular effects of ketamine and its interaction with fentanyl. ( Choi, S; Curay, CM; Irwin, MR; Kiyatkin, EA, 2023)
"Ketamine is said to increase intracranial pressure (ICP), cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) and hence to be unsuitable for neuroanaesthesia."2.39[Cerebral neuroprotection and ketamine]. ( Jantzen, JP, 1994)
"Ketamine pretreatment reduced both of these responses."1.43Ketamine decreases inflammatory and immune pathways after transient hypoxia in late gestation fetal cerebral cortex. ( Arndt, TJ; Chang, EI; Keller-Wood, M; Rabaglino, MB; Richards, EM; Wood, CE; Zárate, MA, 2016)
"Post-treatment with ketamine was associated with partial restoration of energy stores and amino acid content of the left cerebral hemisphere."1.30Effect of ketamine on hypoxic-ischemic brain damage in newborn rats. ( Avgovstides-Savvopoulou, P; Guiba-Tziampiri, O; Karkavelas, G; Loizidis, T; Soubasi, V; Spandou, E, 1999)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Irwin, MR1
Curay, CM1
Choi, S1
Kiyatkin, EA1
Sabharwal, V1
Ramsay, E1
Martinez, R1
Shumate, R1
Khan, F1
Dave, H1
Iwuchukwu, I1
McGrade, H1
Chang, EI1
Zárate, MA1
Rabaglino, MB1
Richards, EM1
Arndt, TJ1
Keller-Wood, M1
Wood, CE1
Shiu, GK1
Nemoto, EM1
Nemmer, J1
Jantzen, JP1
Spandou, E1
Karkavelas, G1
Soubasi, V1
Avgovstides-Savvopoulou, P1
Loizidis, T1
Guiba-Tziampiri, O1
Smith, AL1
Rothman, SM1
Thurston, JH1
Hauhart, RE1
Clark, GD1
Solomon, JS1
Hernándéz-Cáceres, J1
Macias-González, R1
Brozek, G1
Bures, J1

Reviews

2 reviews available for ketamine and Anoxia, Brain

ArticleYear
[Cerebral neuroprotection and ketamine].
    Der Anaesthesist, 1994, Volume: 43 Suppl 2

    Topics: Animals; Brain Diseases; Brain Injuries; Brain Ischemia; Humans; Hypoxia, Brain; Ketamine; Time Fact

1994
Effect of anesthetics and oxygen deprivation on brain blood flow and metabolism.
    The Surgical clinics of North America, 1975, Volume: 55, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics; Anesthetics, Local; Barbiturates; Blood Pressure; Brain; Carbon

1975

Other Studies

7 other studies available for ketamine and Anoxia, Brain

ArticleYear
Basic metabolic and vascular effects of ketamine and its interaction with fentanyl.
    Neuropharmacology, 2023, 05-01, Volume: 228

    Topics: Analgesics, Opioid; Animals; Fentanyl; Humans; Hypoxia; Hypoxia, Brain; Ketamine; Oxygen; Rats

2023
Propofol-ketamine combination therapy for effective control of super-refractory status epilepticus.
    Epilepsy & behavior : E&B, 2015, Volume: 52, Issue:Pt A

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Dissociative; Anesthetics, Intravenous; Chi

2015
Ketamine decreases inflammatory and immune pathways after transient hypoxia in late gestation fetal cerebral cortex.
    Physiological reports, 2016, Volume: 4, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cerebral Cortex; Disease Models, Animal; Female; Fetal Hypoxia; G

2016
Dose of thiopental, pentobarbital, and phenytoin for maximal therapeutic effects in cerebral ischemic anoxia.
    Critical care medicine, 1983, Volume: 11, Issue:6

    Topics: Animals; Brain Chemistry; Brain Ischemia; Fatty Acids, Nonesterified; Female; Hypoxia, Brain; Ketami

1983
Effect of ketamine on hypoxic-ischemic brain damage in newborn rats.
    Brain research, 1999, Feb-20, Volume: 819, Issue:1-2

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Animals, Newborn; Body Weight; Brain; Brain Ischemia;

1999
Ketamine protects hippocampal neurons from anoxia in vitro.
    Neuroscience, 1987, Volume: 21, Issue:3

    Topics: Anesthesia, General; Animals; Culture Techniques; Electrophysiology; Hippocampus; Hypoxia, Brain; Ke

1987
Systemic ketamine blocks cortical spreading depression but does not delay the onset of terminal anoxic depolarization in rats.
    Brain research, 1987, Dec-29, Volume: 437, Issue:2

    Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Hypoxia, Brain; Ketamine; Male; Membrane Po

1987